蒺藜不以多少，炒至赤黑色。臼内外木棒舂去刺，拣，簸净。每蒺藜三两，以酸枣仁一
两炒令香，同杵为粗末，马尾罗筛。每三钱，水一盏，煎至七分，去滓温服，下前丸子药
主脏器不调，大便难。通荣卫、利九窍、进饮食方。
大黄（斗米下蒸，切，焙） 枳壳（去穣，麸炒） 白芍药 葶苈（炒香，别研） 牛
脂（去筋膜，熬成油，与葶苈、杏仁杵） 肉苁蓉（酒浸软，温水洗，切，焙，各一两） 桃
仁（百枚） 杏仁（四十枚，并去皮尖，麸炒黄，别杵）
上除有油药，并为末，炼蜜丸。入牛脂、桃杏仁、葶苈，杵数千下，丸如梧桐子大。
米饮下三丸，日三服。腹稍空时服，未知稍增，以知为度。
安康郡大苦风秘，余为处只可二仁丸。
杏仁（去皮尖，麸炒黄） 麻仁（别研） 枳壳（去穣，麸炒赤） 诃子（慢火炒，捶
去核）
上二物各一两为细末，同二仁杵，炼蜜和杵，丸如梧桐子大。温水下二、三十丸。未知
稍增。
潞公在北门，日盛夏间苦大腹不调。公随行医官李琬，本衢州市户，公不独终始涵容之
，又教以医事。公病泄利，琬以言动摇之，又求速效。即以赤石脂、龙骨、干姜等药馈公，
公服之，不大便者累日，其势甚苦。余方自共城来见公。未坐定，语及此事，公又不喜服大
黄药。余告曰∶此燥粪在直肠，药所不及，请以蜜兑导之，公为然。时七月中苦热，余 汗
为公作蜜兑，是夕三用药，下结粪四、五十枚，大如胡桃，色黑如橡栗。公二、三日间，饮
食已如故。世有一种虚人，不可服利药，今载其法。
蜜兑法 好蜜四、五两，银石器内慢火熬，不住手以匙搅，候可丸；见风硬即以蛤粉涂
手，掐作人指状，长三寸许，坐厕上纳之，以手掩定，候大便通即放手。未快再作。（以上
四方，出初虞世）
Tribulus terrestris (Jili) is not limited in quantity; it is stir-fried until red-black. It is pounded inside and outside a mortar with a wooden pestle to remove the spines, picked clean, and winnowed. For every three taels of Tribulus terrestris, one tael of Ziziphi Spinosae Semen (Suanzaoren) is stir-fried until fragrant, then both are pounded together into a coarse powder and sifted through a horse-hair sieve. Take three qian each time, add one cup of water, decoct until reduced to seven-tenths, strain, and take warm. Follow this by taking the previously mentioned pill medicine.
It mainly treats dysfunction of the zang-fu organs and difficult defecation. This formula regulates Ying and Wei (nutritive and defensive qi), unblocks the nine orifices, and promotes appetite.
Rhei Radix et Rhizoma (Dahuang) is steamed with a dou of rice, sliced, and dried. Aurantii Fructus (Zhike) has its pith removed and is bran-fried. Paeoniae Radix Alba (Baishao). Lepidii Semen (Tinglizi) is stir-fried until fragrant and separately ground. Bovis Medulla (Niuzhi) has tendons and fascia removed, is rendered into oil, and pounded with Tinglizi and Pruni Semen (Xingren). Cistanches Herba (Roucongrong) is soaked in wine until soft, washed with warm water, sliced, and dried (each one tael). Persicae Semen (Taoren) consists of one hundred seeds. Armeniacae Semen Amarum (Xingren) consists of forty seeds, all with skins and tips removed, bran-fried until yellow, and separately pounded.
Except for the oily medicines, all others are made into powder. Add refined honey, then incorporate Niuzhi, Taoren, Xingren, and Tinglizi, pounding for thousands of strokes, and form pills the size of sophora seeds. Take three pills with rice water, three times a day. Take when the abdomen is slightly empty. If ineffective, gradually increase the dose until effective.
A person in Ankang Commandery suffered from severe wind-constipation. I prescribed only Er Ren Wan (Two Kernel Pill) for him.
Armeniacae Semen Amarum (Xingren) has skins and tips removed and is bran-fried until yellow. Cannabis Fructus (Haren) is separately ground. Aurantii Fructus (Zhike) has its pith removed and is bran-fried until red. Chebulae Fructus (Hezi) is slow-fire fried, crushed, and de-seeded.
Each of the above two herbs is taken in one tael amount, made into fine powder, pounded together with the two kernels, mixed with refined honey, pounded evenly, and formed into pills the size of sophora seeds. Take twenty to thirty pills with warm water. Increase the dose slightly if ineffective.
When Duke Lu was stationed at Beimen, during midsummer, he suffered severely from abdominal dysfunction. His attending physician, Li Wan, originally from Quzhou city, was tolerated by the Duke throughout his service and even taught medical skills. When the Duke suffered from diarrhea, Li Wan unsettled him with words and sought quick results. He presented the Duke with drugs such as Halloysit Rubrum (Chishizhi), Longgu (Fossilized Bones), and Zingiberis Rhizoma (Ganjiang). After taking them, the Duke had no bowel movement for several days, suffering greatly. I had just arrived from Gongcheng to see the Duke. Before sitting down, we discussed this matter; the Duke also disliked taking Dahuang-based medicines. I told him: "This is dry fecal impaction in the rectum, inaccessible to oral medication. Please allow me to use honey enema for guidance." The Duke agreed. It was mid-July, extremely hot. I sweated while preparing the honey suppository for the Duke. That evening, after three applications, he passed forty to fifty hard fecal pellets, as large as walnuts, black like acorns. Within two or three days, the Duke's diet returned to normal. There are some deficient patients in the world who cannot tolerate purgatives. Here is the method recorded.
Honey Suppository Method: Take four to five taels of good honey, slowly boil in a silver or earthenware vessel, stirring constantly with a spoon until it can be molded. If it hardens upon exposure to air, coat hands with clam powder, pinch into finger-like shapes about three inches long, sit on the toilet, insert into the anus, hold firmly with hand, and release once defecation occurs. Make another if not fully relieved. (The above four formulas are from Chu Yushi.)