黄 （蜜水炙） 胡黄连 地骨皮 柴胡（各等分）
上为末，炼蜜丸，如芡实大。隔宿酒浸，露一宿，次日澄去酒，薄荷汤浸服之。
钱氏橘连丸 治疳瘦，久服消食、和气、长肌肉。
橘皮（一两） 黄连（米泔浸一宿，一两半）
上为细末，另研入麝香五分，用猪胆七个，分药入胆内，浆水煮，候临熟，以
针微刺破，以熟为度，煮粟米粥和丸，如绿豆大。每服十丸至二三十丸，米饮下，
量儿加减，无时。（海藏云∶黄连苦燥，可以泻脾火，长肌肉。）
二圣丸 治小儿脏腑或好或泻，久不愈，羸瘦，宜常服。
黄连（去须） 黄柏（去粗皮。各一两）
上为细末，入猪胆内重汤煮熟，丸如绿豆大。每服二三十丸，米饮下，量儿加减，频服无妨。
〔张涣〕金粟丹（方见内疳条。）
香蟾丹 治肌瘦面黄，胸高脚细。
干蟾（五枚，水浸，去骨，用瓦藏瓶一枚，顶头上取开，入蟾瓶内，盐泥固济，木炭火烧，留一窍子，以烟息为度，
取出，地上放一宿出火毒） 胡黄连（二两） 蛇蜕皮（一两，烧灰） 地龙（半两，微炒） 天竺黄 蝉壳
（各一分。以上并为细末，次入） 朱砂（半两，细研） 麝香（一分，细研）
上件，都一处研匀，糯米饭和如黍米大。每服十粒，米饮下，不拘时候，量儿大小加减。
《万全方》雷丸丹 治小儿一切疳，肚胀腹满，手脚枯细，眼目口鼻生疮，身体壮
热，痢下泔淀，日渐羸瘦，面无光泽。
雷丸（生） 鹤虱（生） 使君子（去壳，生） 胡黄连（微炒） 芦荟（研。各半两） 麝香（半钱，研入） 蟾
（一枚，酒浸一宿，慢火炙熟，去皮足骨焙） 木香 肉豆蔻（各一分） 芜荑（一两，去皮微炒，研入） 朱砂（二
钱，研，留少许为衣）
上件药捣，罗为末，研合令匀，用 猪胆四个取汁，倾入瓷盏中，外以重汤煮
过，和杵为丸如黍米大。每服五丸至七丸，麦门冬熟水下，早晨日午空心临卧服。
〔孔氏〕神圣丸 肥、小儿疳药，常服永无肠脏之疾。
胡黄连（去皮） 宣连（去毛） 白芜荑（去皮） 木香 芦荟（各一钱） 使君子（二十枚）
上，除芦荟一味，外五味银器内用猪胆汁熬成膏，后入芦荟同丸如绿豆大。每
服五七粒，空心日午临卧米汤下，神效。
猪肚丸 治小儿疳热而瘦。
柴胡 黄连 秦艽（各一两，净） 芜荑（二两，用瓦上爆干，去壳取肉，别为末，临时入用）
上，用猪肚一个，中庸者，破开净洗，入前药三味末于内，以酒半瓶、童子小
便一升，煮干，舂令得所，放芜荑末，又舂匀，丸如桐子大。每服二十丸，饮下。
《王氏手集》治小儿疳瘦，大人五劳七伤方。
宣黄连（半斤，去须及芦头，为细末） 猪肚（一个，去脂膜，将黄连末穣在内，缝合，于三斗米内蒸，以米熟
软为度）
上件，取出烂研，丸如粟米大，风干。随儿大小加减，日三服，三岁儿每服五
七丸至十丸，大人服如桐子大，每服二十丸，空心米饮下。
〔赵氏〕斧捶丸 治小儿疳，久服肥白。
干虾蟆（一枚） 白矾 胆矾 绿矾（各半两，四味同入罐子内，炭火烧，矾枯为度） 京三棱 石三
棱鸡爪三棱 萆 鹤虱 雷丸 淡芜荑 黑狗脊 木香（各半两） 没石子（三枚）
使君子（十枚） 芦荟 熊胆（各一钱）
上为末，醋煮干枣取肉烂研，入少面糊和药极熟，丸如绿豆大。每服七丸，米饮下。
玉拄杖散 治小儿疳瘦。
黄 （二两） 白茯苓（半两） 人参 白术（各一两）
上为末。以水一盏，药一钱，煎七分，温服。
芦荟丸 治小儿诸疳羸瘦，不生肌肉。
芦荟 木香 红芍药 没石子（各半两） 使君子（去壳） 胡黄连（各二钱半） 肉豆蔻（二钱） 人参（一钱）
上为细末，入麝香半钱，别研令细，与药拌匀，蜜水打面糊为丸。每服十五丸，
米饮下，空心食前服。
〔吉氏〕益儿丸 治小儿一切疳瘦，夜多盗汗，肌肉热。
人参 白术 茯苓 柴胡（去苗） 甘草（炙） 陈皮（去白） 鳖甲（醋炙，去裙 ） 京三棱（湿纸裹，
煨香熟。各等分）
上细末，炼蜜丸，如鸡头实大。每服一丸，米饮化，食前，日三服。
《朱氏家传》肥儿丸
白芜荑（去壳秤） 黄连（去须） 神曲 麦 （各等分）
上为末，用 猪胆煮糊，丸如大麻子大。每服三十丸，食前，米饮下。《张氏家
传》《庄氏家传》方皆同，或治疳积，或治疳瘦。
六味肥儿丸 治疳多因缺乳，食肉太早，或患脏腑胃虚，疗诸般疳，化虫，治黄瘦
肚急，消疳退疳热可常服。
黄连（《局方》加肉豆蔻） 陈皮（去白，《局方》去此，用木香） 神曲（炒，《局方》有使君子） 麦 （炒。各
一两，《局方》加三棱、蓬术） 川楝肉（一两炒） 白芜荑（半两，《局方》去此，用槟榔）
上为末，神曲糊丸，麻子大。每服三十丸，空心、米饮吞下。
〔薛〕按∶前方，又治脾疳，饮食少思，肌肉消瘦，肚大颈细，发稀成穗，项
间结核，发热作渴，精神倦怠，大便酸臭，嗜食泥土，或口鼻头生疮，肚见青筋，
啮齿下利，便白五疳。用此丸加干蟾一两、芦荟五钱，尤妙。
秘方肥儿丸 消疳进食。
黄连（五钱） 木香（一钱） 神曲 麦 （各一两，并炒） 使君肉（煨） 肉豆蔻（面裹煨，各五钱） 槟榔
（一枚） 虾蟆（一个） 白术（一两）
上为末，面糊丸，如粟米大。空心米饮下，量儿加减。
《朱氏家传》治小儿脾疹疳瘦惊积方
上用黄栝蒌一个，去瓤，用黄连末填满，蒸烂取出，用朴硝末一钱、盖头，临
夜方取，然后露一宿，研烂为丸如小绿豆大。每服五丸，熟水下。
洁古云∶小儿疳病肌瘦，血气不足，同大人劳瘵之疾治之。
按∶以洁古此论详之，不拘冷热虚羸，皆用四君子、地黄丸与前药相兼服
为得也。然有胸膈积瘀，不受参术地黄之补者，先用清疳取积之药，然后补剂可
施，故备载诸方，以俟采择，诚以病之变态多端，非执一隅可以御百变，若看方
三年，无病不治者，鲜不以为繁杂矣。
Huang (processed with honey water) Hu Huang Lian (Coptidis Rhizoma) Di Gu Pi (Lycii Cortex) Chai Hu (Bupleuri Radix) (equal parts)
Grind the above ingredients into fine powder. Make pills with refined honey, sized like Euryale Seed (Qian Shi). Soak overnight in wine, expose to dew for one night, clarify and remove the wine the next day, and take with Mint Decoction (Bo He Tang).
Qian's Ju Lian Wan (Tangerine Peel and Coptis Pill): Treats malnutrition emaciation (Gan syndrome). Long-term use promotes digestion, harmonizes Qi and blood, and builds muscle.
Ju Pi (Tangerine Peel, 1 liang) Huang Lian (Coptidis Rhizoma, soaked in rice washing water overnight, 1.5 liang)
Grind the above ingredients into fine powder. Separately grind She Xiang (Musk, 0.5 qian). Take seven pig gallbladders, divide the powder into them, and boil in starch water. When nearly cooked, pierce slightly with a needle until fully cooked. Mix with millet porridge to form pills sized like mung beans. Take 10 to 20-30 pills per dose with rice drink, adjusting dosage according to age, at any time. (Zhang Yuansu stated: Huang Lian is bitter and drying, can clear Spleen fire, and build muscle.)
Er Sheng Wan (Two Sage Pills): Treats pediatric organ dysfunction, alternating constipation and diarrhea, chronic and unhealed, leading to emaciation. Suitable for regular use.
Huang Lian (Coptidis Rhizoma, remove stamens) Huang Bo (Phellodendri Cortex, remove rough bark) (each 1 liang)
Grind the above ingredients into fine powder, place inside a pig gallbladder, and cook thoroughly over boiling water. Form pills sized like mung beans. Take 20-30 pills per dose with rice drink, adjusting dosage according to age. Frequent administration is acceptable.
[Zhang Huan] Jin Su Dan (Golden Millet Pill) (Formula see "Internal Gan" section.)
Xiang Chan Dan (Toad Fragrance Pill): Treats muscular emaciation, sallow complexion, high chest, and thin legs.
Gan Chan (Dried Toad, 5 pieces, soak in water, remove bones. Use one clay jar, open from the top, insert toad into jar, seal tightly with salt mud, burn with charcoal leaving one small vent, stop when smoke ceases. Remove and place on ground overnight to eliminate fire toxicity) Hu Huang Lian (Coptidis Rhizoma, 2 liang) She Tui Pi (Ophichthys Skin, 1 liang, burnt to ash) Di Long (Pheretima, 0.5 liang, lightly stir-fried) Tian Zhu Huang (Calami Tuber) Chan Qiao (Cicada Slough) (each 1 fen. Grind all above into fine powder, then add) Zhu Sha (Cinnabar, 0.5 liang, finely ground) She Xiang (Musk, 1 fen, finely ground)
Mix all ingredients uniformly, combine with glutinous rice paste to form pills sized like millet seeds. Take 10 pills per dose with rice drink, at any time, adjusting dosage according to child's size.
Wan Quan Fang Lei Wan Dan (Lei Wan Pill from Wan Quan Formula): Treats all types of pediatric Gan syndrome, abdominal distension and fullness, withered and thin limbs, sores around eyes, mouth, and nose, high fever, dysentery resembling rice water, progressive emaciation, and lackluster complexion.
Lei Wan (Albiziae Semen, raw) Shi Ni (Chrysanthemi Indici Fructus, raw) Shi Jun Zi (Quisqualis Fructus, shelled, raw) Hu Huang Lian (Coptidis Rhizoma, lightly stir-fried) Lu Hui (Aloe, ground) (each 0.5 liang) She Xiang (Musk, 0.5 qian, ground and added) Chan (Toad, 1 piece, soaked in wine overnight, slow-roasted until cooked, skin and bones removed and baked) Mu Xiang (Aucklandiae Radix) Rou Dou Kou (Myristicae Semen, each 1 fen) Wu Yi (Terminaliae Chebulae Fructus, 1 liang, shelled, lightly stir-fried, ground and added) Zhu Sha (Cinnabar, 2 qian, ground, reserve some for coating)
Pound the above ingredients, sieve into powder, mix thoroughly. Extract juice from four pig gallbladders, pour into a porcelain cup, boil externally over water, mix with pestle to form pills sized like millet seeds. Take 5-7 pills per dose with熟水 (cooked water) prepared with Ophiopogonis Radix (Mai Men Dong), taken in the morning, at noon on an empty stomach, and before bed.
[Kong Shi] Shen Sheng Wan (Divine Holy Pill): For fattening children and treating pediatric Gan syndrome. Regular use prevents internal organ diseases.
Hu Huang Lian (Coptidis Rhizoma, peeled) Xuan Lian (Coptidis Rhizoma, de-haired) Bai Wu Yi (Terminaliae Chebulae Fructus, peeled) Mu Xiang (Aucklandiae Radix) Lu Hui (Aloe) (each 1 qian) Shi Jun Zi (Quisqualis Fructus, 20 pieces)
Except for Aloe, place the other five herbs in a silver vessel, simmer with pig bile to form a paste. Add Aloe and form pills sized like mung beans. Take 5-7 pills per dose with rice soup on an empty stomach, at noon, and before bed. Divine effect.
Zhu Du Wan (Pig Stomach Pill): Treats pediatric Gan heat and emaciation.
Chai Hu (Bupleuri Radix) Huang Lian (Coptidis Rhizoma) Qin Jiao (Gentianae Macrophyllae Radix) (each 1 liang, cleaned) Wu Yi (Terminaliae Chebulae Fructus, 2 liang, dried on tile, shelled, meat separated, ground into powder separately for late addition)
Take one medium-sized pig stomach, cut open and clean thoroughly. Insert the three powdered herbs into the stomach. Add half a bottle of wine and one sheng of urine from a young boy. Boil until dry. Pound to appropriate consistency. Add Wu Yi powder, pound again to mix evenly. Form pills sized like Sophora Seeds (Tong Zi). Take 20 pills per dose with water.
Wang Shi Shou Ji (Wang Family Hand Collection) Formula for Pediatric Gan Emaciation and Adult Five Exhaustions and Seven Injuries.
Xuan Huang Lian (Coptidis Rhizoma, 0.5 jin, remove stamens and rhizome head, grind to fine powder) Zhu Du (Pig Stomach, 1 piece, remove fat membrane, stuff with Huang Lian powder, sew shut, steam in three dou of rice until rice is soft and cooked)
Remove ingredients, pound and grind thoroughly. Form pills sized like millet seeds, air-dry. Adjust dosage according to child's size. Take three times daily. For a three-year-old, take 5-7 to 10 pills per dose. For adults, take pills sized like Sophora Seeds, 20 pills per dose, with rice drink on an empty stomach.
[Zhao Shi] Fu Chui Wan (Axe-Pounded Pill): Treats pediatric Gan syndrome. Long-term use leads to plumpness and fair skin.
Gan Xia Ma (Dired Toad, 1 piece) Bai Fan (Alumen) Dan Fan (Melanterite) Lv Fan (Chalcanthite) (each 0.5 liang, put together in a jar, burn with charcoal until salts are dry and brittle) Jing San Leng (Sparganii Rhizoma) Shi San Leng (Sparganii Rhizoma) Ji Zhua San Leng (Sparganii Rhizoma) Bi Xie (Dioscoreae Hypoglaucae Rhizoma) Shi Ni (Chrysanthemi Indici Fructus) Lei Wan (Albiziae Semen) Dan Wu Yi (Terminaliae Chebulae Fructus) Hei Gou Ji (Canis Spina Dorsalis) Mu Xiang (Aucklandiae Radix) (each 0.5 liang) Mei Shi Zi (Chebulae Terminaliae Fructus, 3 pieces) Shi Jun Zi (Quisqualis Fructus, 10 pieces) Lu Hui (Aloe) Xiong Dan (Ursi Bile) (each 1 qian)
Grind into powder. Boil dried dates in vinegar, take flesh and pound thoroughly. Add small amount of flour paste to mix well with medicine. Form pills sized like mung beans. Take 7 pills per dose with rice drink.
Yu Zhu Zhang San (Jade Crutch Powder): Treats pediatric Gan emaciation.
Huang Qi (Astragali Radix, 2 liang) Bai Fu Ling (Poria, 0.5 liang) Ren Shen (Ginseng Radix) Bai Zhu (Atractylodis Macrocephalae Rhizoma) (each 1 liang)
Grind into powder. Use one cup of water, one qian of medicine, decoct to 0.7 cup. Take warm.
Lu Hui Wan (Aloe Pill): Treats various pediatric Gan syndromes with emaciation and failure to build muscle.
Lu Hui (Aloe) Mu Xiang (Aucklandiae Radix) Hong Shao Yao (Paeoniae Radix Rubra) Mei Shi Zi (Chebulae Terminaliae Fructus) (each 0.5 liang) Shi Jun Zi (Quisqualis Fructus, shelled) Hu Huang Lian (Coptidis Rhizoma) (each 2.5 qian) Rou Dou Kou (Myristicae Semen, 2 qian) Ren Shen (Ginseng Radix, 1 qian)
Grind into fine powder. Add She Xiang (Musk, 0.5 qian), grind separately until fine, mix evenly with medicine. Make pills with honey-water flour paste. Take 15 pills per dose with rice drink, on an empty stomach before meals.
[Ji Shi] Yi Er Wan (Benefit Child Pill): Treats all pediatric Gan emaciation, night sweats, and hot muscles.
Ren Shen (Ginseng Radix) Bai Zhu (Atractylodis Macrocephalae Rhizoma) Fu Ling (Poria) Chai Hu (Bupleuri Radix, remove sprouts) Gan Cao (Licorice Root, roasted) Chen Pi (Citri Reticulatae Pericarpium, remove white pith) Bie Jia (Testudinis Carapax et Plastrum, vinegar-processed, remove skirt-like edges) Jing San Leng (Sparganii Rhizoma, wrapped in wet paper, baked until fragrant and cooked) (equal parts)
Grind into fine powder. Make pills with refined honey, sized like Euryale Seeds (Ji Tou Shi). Take one pill per dose, dissolve in rice drink, before meals, three times daily.
Zhu Family Tradition Fei Er Wan (Fattening Child Pill)
Bai Wu Yi (Terminaliae Chebulae Fructus, shelled and weighed) Huang Lian (Coptidis Rhizoma, remove stamens) Shen Qu (Massae Medicamentosa Fermentata) Mai Ya (Hordei Fructus Germinatus) (equal parts)
Grind into powder. Cook paste with pig bile. Form pills sized like hemp seeds. Take 30 pills per dose before meals with rice drink. The formulas from Zhang Family Tradition and Zhuang Family Tradition are identical, treating either Gan accumulation or Gan emaciation.
Liu Wei Fei Er Wan (Six-Ingredient Fattening Child Pill): Treats Gan syndrome often caused by milk deficiency, early introduction of meat, or Spleen/Stomach deficiency. Treats various Gan syndromes, expels parasites, treats yellow emaciation and urgent abdomen, reduces Gan heat. Can be taken regularly.
Huang Lian (Coptidis Rhizoma, [Ju Fang] adds Rou Dou Kou) Chen Pi (Citri Reticulatae Pericarpium, remove white pith, [Ju Fang] removes this, uses Mu Xiang) Shen Qu (Massae Medicamentosa Fermentata, stir-fried, [Ju Fang] has Shi Jun Zi) Mai Ya (Hordei Fructus Germinatus, stir-fried, each 1 liang, [Ju Fang] adds San Leng and Peng Ze) Chuan Lian Rou (Toosendan Fructus, 1 liang, stir-fried) Bai Wu Yi (Terminaliae Chebulae Fructus, 0.5 liang, [Ju Fang] removes this, uses Bing Lang)
Grind into powder. Make pills with Shen Qu paste, sized like sesame seeds. Take 30 pills per dose on an empty stomach with rice drink.
[Xue Ji] Commentary: The previous formula also treats Spleen Gan, characterized by poor appetite, emaciation, large abdomen and thin neck, sparse hair forming tufts, lymph node swelling in the neck, fever with thirst, mental fatigue, sour-smelling stool, pica (eating dirt), sores on face/nose/mouth, visible blue veins on abdomen, teeth grinding, diarrhea, and white worms in stool (Five Gan syndromes). Adding 1 liang of Gan Chan (Dried Toad) and 5 qian of Lu Hui (Aloe) to this pill yields excellent results.
Secret Recipe Fei Er Wan (Fattening Child Pill): Reduces Gan, promotes appetite.
Huang Lian (Coptidis Rhizoma, 5 qian) Mu Xiang (Aucklandiae Radix, 1 qian) Shen Qu (Massae Medicamentosa Fermentata) Mai Ya (Hordei Fructus Germinatus) (each 1 liang, stir-fried) Shi Jun Zi Ren (Quisqualis Fructus Kernel, baked) Rou Dou Kou (Myristicae Semen, wrapped in flour and baked) (each 5 qian) Bing Lang (Arecae Semen, 1 piece) Xia Ma (Toad, 1 piece) Bai Zhu (Atractylodis Macrocephalae Rhizoma, 1 liang)
Grind into powder. Make pills with flour paste, sized like millet seeds. Take with rice drink on an empty stomach, adjust dosage according to age.
Zhu Family Tradition Formula for Pediatric Spleen Rash, Gan Emaciation, and Accumulation with Startles.
Take one Huang Gua Lou (Trichosanthis Fructus), remove pulp, fill with Huang Lian powder. Steam until soft, remove. Cover with 1 qian of Xiao Ming Fan (Mirabilite powder). Take only at night. Expose to dew overnight. Grind thoroughly to form pills sized like small mung beans. Take 5 pills per dose with cooked water.
Jie Gu stated: Pediatric Gan syndrome involves muscular emaciation and insufficiency of Qi and Blood; treat it similarly to adult Lao Zhai (Consumption disease).
Commentary: Based on Jie Gu's discussion, regardless of cold/heat or deficiency/emaciation, combining Si Jun Zi Tang (Four Gentlemen Decoction), Di Huang Wan (Rehmannia Pill), and the aforementioned medicines is appropriate. However, if there is stagnation and blood stasis in the chest and diaphragm, preventing tolerance of tonics like Ren Shen, Bai Zhu, and Di Huang, first use drugs to clear Gan and remove accumulation, then apply tonification. Therefore, various formulas are recorded for selection. Indeed, disease manifestations are diverse; one cannot handle hundreds of changes by adhering to a single aspect. Those who study formulas for three years claiming no disease is incurable rarely fail to find them complex.