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Wu stated: Qi and blood move freely when exposed to fragrance, but become reversed when exposed to foul odors. Generally speaking, sores and ulcers often arise because Ying (Nutritive) Qi fails to follow its proper course, reversing within the muscle tissue, thus stagnating and accumulating into pus. Upon receiving aromatic dispersing medicines, Qi circulation is restored; therefore, one should take Wuxiang Liaoqiao Tang (Five-Aromatic Liaoqiao Decoction), Wanjin San (Myriad-Gold Powder), and Qingxin Neigu Jinfen San (Clear-Heart Inner-Solidifying Gold-Dust Powder) frequently. Any sore that inherently has a fishy or foul odor will worsen if exposed to further foul smells, as turbidity increases. If toxic vapors enter the stomach, it leads to coughing and rebellious Qi. The ancients' use of this principle was reasonable; furthermore, adjusting diet to be fragrant and delicious benefits Spleen Earth and nourishes True Yuan, ensuring safety.

Lizhai stated: Nowadays, patients with sores and ulcers do not examine whether their Yuan Qi (Primal Qi) is deficient or excess, nor whether the disease is in the exterior or interior. Patients often prefer internal resolution, and physicians immediately prescribe Shixuan San (Ten-Exterior Dispelling Powder), Baidu San (Resolving-Toxicity Powder), or Liqi Yin (Qi-Circulating Decoction). Little do they know that although Shixuan San contains Renshen (Ginseng Radix et Rhizoma), Fangfeng (Saposhnikoviae Radix), Baizhi (Angelicae Dahuricae Radix), Houpo (Magnoliae Officinalis Cortex), and Jiegeng (Platycodonis Radix) are all capable of depleting Qi. Moreover, using them indiscriminately without considering meridians, seasons, and the varying amounts of Qi and blood is inappropriate. Baidu San is an exterior-releasing formula; even if there are exterior signs, it should only be taken once or twice. Excessive use damages Yuan Qi, causing toxicity to flourish; even with Renshen, recovery is difficult, especially when no exterior syndrome exists. Liqi Yin is a blood-depleting agent; even for Qi stagnation with chest fullness, it should only be taken two or three times. Overuse injures Qi and blood. Blood and Qi stagnation usually result from weak Ying and Wei (Defensive) Qi failing to circulate properly; how can Liqi Yin be used to exacerbate deficiency? Furthermore, since Qi and blood vary among meridians, Liqi Yin's action across the Twelve Meridians damages all of them, leading to deteriorating conditions. Even with Chuanxiong (Ligustici Chuanxiong Rhizoma) and Danggui (Angelicae Sinensis Radix), reliance is futile. Excessive intake causes Qi deficiency and blood depletion, preventing pus formation. Without investigating the cause and indiscriminately administering attacking agents, danger is inevitable. It is clear that these three formulas should not be used lightly. Hejian stated: Sores confined to one meridian, or involving two, should be treated by addressing that specific meridian, without disturbing others.

Huaihua (Sophorae Flavescentis Flos) is most effective and rapid in clearing damp-heat and reducing fever. Generally, for swelling and toxicity, if Suanjio (Garlic Moxibustion) and Huaihua Jiu (Sophora Flower Wine) are not used first to subdue the pathogenic force, even with Toli (Supporting-the-Interior) herbs, efficacy may not be swift. Only those with Stomach Cold should avoid excessive use.

Yu Shiyu of Chuzhou suffered severe pain from toxicity in his thigh and scapula. After taking detoxifying herbs without reduction in severity, one dose of Huaihua Jiu caused the condition to recede significantly. Subsequent treatment with Toli detoxifying herbs led to recovery.

Wang Tongfu suffered from Fabei (Back Carbuncle) for over ten days, with critical condition and a large pulse. Two doses of Huaihua Jiu subdued the toxicity. This was followed by two doses of Baidu San, then several doses of Toli herbs until gradual suppuration occurred. Sangchai moxibustion (Moxibustion with Mulberry Wood) was applied to the affected area for long periods daily, along with plaster application. After several sessions, pus drained and necrotic tissue detached. Toli herbs were supplemented with Baizhu (Atractylodis Macrocephalae Rhizoma) and Chenpi (Citri Reticulatae Pericarpium), resulting in recovery after more than a month.

Liu Dayin suffered from Fabei for six or seven days, with widespread back swelling and pain, indicating critical severity. He received 100 moxa cones via Ge Suan Jiu (Garlic-Separated Moxibustion) and drank two bowls of Huaihua Jiu, waking up refreshed. Toli detoxifying herbs reduced the pathology by five or six parts. Sangzhi moxibustion (Moxibustion with Mulberry Twig) was applied to induce suppuration, leading to recovery within days.

A Shangshe (Imperial Student) suffered from Ju (Carbuncle) on the shoulder with a rapid pulse. One dose of Huaihua Jiu caused immediate recession of toxicity. Subsequently, Yinhua (Lonicerae Japonicae Flos), Huangqi (Astragali Radix), and Gancao (Glycyrrhizae Radix et Rhizoma) were administered for over ten doses, leading to resolution. (Commentary by Xue Ji)