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Patients generally tend to be irritable, which is a common occurrence. However, the anger caused by plague (wen yi) differs from the irritability seen in ordinary diseases. The symptoms manifest as follows: sometimes, due to slight verbal discord or minor accidental disharmony, situations that would normally be met with laughter and playfulness now provoke immediate, unresolvable rage upon hearing them. The patient harbors secret annoyance incessantly; when consciousness becomes clouded, they may involuntarily vocalize the objects of their anger through delirious speech (chan yu). Alternatively, without any external provocation, merely recalling past annoyances can trigger frequent outbursts of anger, causing a sensation of depression, distension, and blockage in the chest and abdomen. This resembles "ao nao" (a state of profound restlessness and frustration) but is fundamentally different. In medical formularies, "ao nao" is described as a feeling of depression and discomfort, accompanied by a sense of helplessness, being more severe than mere vexation. It typically arises after purgative treatment and occurs spontaneously without external triggers. In contrast, this condition of "excessive anger" (shan nu) persists daily regardless of whether diaphoresis or purgation has been employed. There are even cases where the plague has resolved, yet this symptom remains, ceasing only when the patient regains the ability to rise and move about as usual. One might argue that this symptom does not originate from the Liver and Gallbladder meridians, yet these meridians govern anger. Conversely, if the anger stems entirely from the Liver and Gallbladder, why do they not bear the blame? The reason is that even after the pathogenic factors of plague in the Liver and Gallbladder have subsided, the anger persists. Only by administering qi-regulating formulas can the depression be slightly alleviated; however, even if alleviated, the condition may recur upon any triggering stimulus. This presentation resembles "Yang Jue" (Yang Reversal) but is not identical. Texts state that Yang Jue manifests as anger and madness due to the sudden obstruction and difficulty in resolving Yang Qi, hence the name. Because Yang Qi is suddenly obstructed, it leads to stagnation and excessive anger. Treatment involves Tieluo Yin (Iron Falling Decoction) with a small amount of Zhensha (Cinnabar), based on the principle that Metal generates Water. Iron is heavy in nature and excels at descending heat and resolving knots. True Yang Jue must present with cold limbs (jue ni) to warrant the name "Jue." Furthermore, "anger leading to madness" implies mania rather than mere anger. In this case, there is no limb reversal nor madness; rather, there is internal secret annoyance that is involuntary, hence the name "Shan Nu" (Excessive Anger). Although the chest and abdomen feel severely constrained, fatalities from this specific symptom alone are rare. The primary approach is to treat the plague directly; once the plague resolves, the anger will naturally cease. Alternatively, Tieluo Yin may be administered, modified according to accompanying symptoms, to achieve efficacy.