严用和云素问谓疟生于风又夏伤于暑此四时之气也或乘凉饮冷当风卧湿饥饱失时致脾胃
不和痰积中脘遂成此疾所谓无痰不成疟一日一发易治间日一发难愈三日一发者尤其难愈
按此谓胃气不和痰积中脘而成疟则自内而生病于外也与素问风暑外伤虽异然外既受伤则
内气
必郁亦生痰此自外而生病于内也疟而挟痰诚有之矣其引以无痰不成疟之一句则失之偏也其用
药治法亦且未详
病机机要云经曰夏伤于暑秋必 疟伤之浅者近而暴伤之重者远而为 者久疟也是知夏
伤暑气
闭而不能发泄于外邪气内行至秋而为疟也有中三阳者有中三阴者其证各殊同伤寒也在太阳经
谓之寒疟治多汗之在阳明经谓之热疟治多下之在少阳经谓之风疟治多和之此三阳受病谓之暴
疟发在夏至后处暑前此乃伤之浅者近而暴也在阴经则不分三经总谓之湿疟当从太阴经论之发
在处暑后冬至前此乃伤之重者远而为 者老也居西方宜毒药疗之
按此分风暑所伤有阴阳浅深之异发前人所未论也
详见后论中
子和云内经既以夏伤于暑而为疟何世医皆以脾寒治之用姜附硫黄之类甚者归之祟怪良可
笑耶
又或因夏月饮食生冷之类指为食疟此又非也岂知内经之论则不然皆夏伤于暑遇秋风寒而后作
也邪热浅则连日邪热深则间日并入于里则寒并入于表则热若此论则了不相干于脾也治平之时
其
民夷静虽用砒石辰砂有毒之药以热治热亦能取效扰攘之时其民劳苦内火与外火俱动以热攻热
转为吐血泻血疮疡呕吐之疾岂与夷静之人同治哉余尝用张长沙汗吐下三法愈疟病极多大忌错
作脾寒治之
按此云无脾寒及鬼疟皆是得之于暑又谓平治与扰攘之时治疟不同皆确论也然食疟则世亦
有之
者然观其用药以白虎加人参汤小柴胡五苓桂苓甘露之类则调之也甚者脏用承气大紫胡下之更
不愈以常山散吐之悉是寒药降火之剂盖以疟从火之化也又有谓治刍荛贫贱之人与富贵膏粱不
同之论固是然仍用温脾散辰砂丹劫药贫贱之人岂与治平时人同欤贫贱者脾胃虚寒其可用劫剂
欤此恐非出于子和之笔也学人试思之
或问俗以疟为脾寒何也曰此亦有理天地之间惟吴楚闽广人患此至多为阳气之所盛处其地
卑湿
长夏之时人多患 疟霍乱泻痢伤湿热也本暑盛阳极人伏阴在内脾困体倦腠理开发或因纳凉于
水间木阴及泉水澡浴而微寒客于肌肉之间经所谓遇夏气凄怆之小寒迫之是也或劳役饥饱内伤
而即病作故指肌肉属脾发则多恶寒战栗乃谓之脾寒尔实由风寒湿 之邪郁于腠理夏时毛窍疏
通而不为病至秋气敛之际表邪不能发越故进退不已往来寒热病势如凌疟人之状所以名疟即
四时之伤寒故十二经皆能为病古方治法多兼于理内伤取效脾胃和而精气疏通阴阳和解诸邪悉
散此实非脾病也但病气随经升降其发早暮日次不等内经具病例已详专世以发表解肌温经散寒
等法亦未尝执于燥脾劫剂也又曰既疟本夏伤于暑为病世有不服药饵或人与符咒厌之亦止何也
曰此夏时天地气交百物生发湿热熏蒸禽虫吐毒之际人因暑热汗出神气虚耗感得时间乖戾之气
为病故与厌之亦止若移精变气之谓也然古人称疟不得为脾寒者正恐人专于温脾之说不明造化
之源而失病机气宜之要故也
Yan Yonghe stated: The *Suwen* (Basic Questions) mentions that malaria arises from wind pathogens, and also states that it results from summer heat injury. These are influences of the qi of the four seasons. Some people cool themselves, drink cold substances, lie in the wind, dwell in dampness, or suffer from irregular eating habits, leading to disharmony of the spleen and stomach and accumulation of phlegm-dampness in the middle jiao (middle burner), thus forming this disease. This is what is meant by "no phlegm, no malaria." Malaria occurring once a day is easy to treat; occurring every other day is difficult to cure; occurring every three days is even more difficult to cure.
Commentary: Here, it is said that malaria is formed due to disharmony of stomach qi and accumulation of phlegm in the middle jiao, meaning illness originates internally and manifests externally. Although different from the *Suwen*'s description of wind and summer heat invading from the exterior, once the exterior is injured, internal qi must become stagnant, which also generates phlegm; this means illness originates externally and affects internally. It is true that malaria can be complicated by phlegm, but citing the phrase "no phalkm, no malaria" is biased. The medication and treatment methods are not detailed.
*Bingji Jiyao* (Essentials of Pathogenesis) states: The classic says, "Summer injury by summer heat leads to malaria in autumn." If the injury is shallow, onset is near and sudden; if severe, onset is distant and prolonged. Thus, it is known that summer heat qi becomes closed and cannot vent outward; the pathogen moves inward, and upon reaching autumn, malaria erupts. There are cases involving the Three Yang meridians and those involving the Three Yin meridians, with distinct syndromes, similar to Cold Damage (Shanghan). Involvement of the Taiyang meridian is called Cold Malaria, treated mostly with sweating methods; involvement of the Yangming meridian is called Heat Malaria, treated mostly with purgation methods; involvement of the Shaoyang meridian is called Wind Malaria, treated mostly with harmonizing methods. Illness in these Three Yang meridians is called Sudden Malaria, occurring between Summer Solstice and End of Heat, representing shallow injury with near and sudden onset. Involvement of the Yin meridians, regardless of the specific meridian, is collectively called Damp Malaria, discussed primarily through the perspective of the Taiyin meridian. Occurring between End of Heat and Winter Solstice, this represents severe injury with distant and prolonged onset. Those residing in the West are suitable for treatment with toxic drugs.
Commentary: This distinguishes the differences in yin/yang, depth/shallowness, and severity of wind and summer heat injuries, expounding on points not previously discussed. See further discussion below.
Zi He (Zhang Congzheng) said: Since the *Neijing* (Inner Canon) attributes malaria to summer heat injury in summer, why do later physicians all treat it as Spleen Cold? Using herbs such as Ganjiang (Dried Ginger), Fuzi (Prepared Aconite Root), and Liuhuang (Sulfur), and in severe cases attributing it to demonic influence, is truly laughable!
Furthermore, some attribute it to Food Malaria because of consuming raw and cold foods in summer, which is also incorrect. Does one not know that the *Neijing* does not say this? All cases involve summer heat injury followed by onset upon encountering autumn wind-cold. If pathogenic heat is shallow, it occurs daily; if deep, it occurs every other day. Entering interior causes chills; entering exterior causes fever. Such explanations have nothing to do with the Spleen. In times of peace, when people are tranquil, even using toxic drugs like Pishi (Realgar) and Chensha (Cinnabar) to treat heat with heat can yield results. However, in times of turmoil, when people are laborious and suffering, internal fire and external fire move together; treating heat with heat may turn into hematemesis, hematochezia, sores, ulcers, and vomiting. How can they be treated the same as tranquil people? I once used Zhang Zhongjing's sweating, vomiting, and purging methods to cure many malaria patients. It is strictly forbidden to mistakenly treat it as Spleen Cold.
Commentary: This states there is no Spleen Cold or Ghost Malaria, but rather acquisition from summer heat, and that treatment differs between peaceful and turbulent times; these are accurate discussions. However, Food Malaria does exist in the world. Observing his medications, such as Baihu Jia Renshen Tang (White Tiger Plus Ginseng Decoction), Xiaochaihu Tang (Minor Bupleurum Decoction), Wuling San (Five-Ling Powder), Guiling Ganlu Yin (Cassia Twig and Poria Sweet Dew Drink), these are regulating agents. For severe cases, Chengqi Tang (Chengqi Decoction) or Dachaihu Tang (Major Bupleurum Decoction) are used for purging; if still uncured, Changsan San (Changshan Powder) is used to induce vomiting. All are cold-natured drugs that descend fire, likely because malaria transforms from fire. There is also a theory that treating poor/commoners differs from treating wealthy/nourished individuals. While correct, using Wenspi San (Warm Spleen Powder) and Chensha Dan (Cinnabar Pill), which are coercive drugs, on poor people—can they be treated the same as ordinary people? Poor people have deficient-cold spleen and stomach; how can coercive drugs be used? This is likely not written by Zi He; students should ponder this.
A question was asked: Why do common people consider malaria to be Spleen Cold? The answer is: There is reason for this. Among all regions under heaven, only Wu, Chu, Min, and Guang regions have the highest incidence, because these are places where yang qi is abundant, terrain is low and damp. During late summer, people often suffer from malaria, cholera, and dysentery, damaging them with damp-heat. At this time, summer heat is extreme; extreme yang implies hidden yin within, causing spleen stagnation and fatigue, and opening of the cou li (pores). Some cool off by water, rest in tree shade, or bathe in springs, allowing slight cold to lodge in the muscles. This is what the Classic calls "encountering the chilling small cold of summer air pressing upon one." Or, illness arises immediately due to internal injury from labor or irregular diet. Therefore, muscles are attributed to the Spleen; during attacks, there is often aversion to cold and shivering, hence called Spleen Cold. Actually, it is caused by wind-cold-damp pathogens stagnating in the cou li. In summer, pores are open and no disease occurs; when autumn qi converges, exterior pathogens cannot vent, so they advance and retreat endlessly, causing alternating chills and fever. The condition feels like the person is being tormented, hence named Malaria, which is essentially Cold Damage of the four seasons; thus, all twelve meridians can be affected. Ancient formulas often combine regulation of internal injury. Efficacy lies in harmonizing the spleen and stomach, unblocking essence and qi, reconciling yin and yang, and dispersing all pathogens. This is truly not a disease of the Spleen itself. Only the pathogenic qi ascends and descends along the meridians, with varying onset times. The *Neijing* details these cases thoroughly. People generally use only exterior-releasing, muscle-relaxing, meridian-warming, and cold-dispersing methods, without adhering strictly to drying-spleen coercive agents. Another question: Since malaria is fundamentally caused by summer heat injury in summer, why do some stop the disease without medicine, or by having others chant spells to suppress it? The answer is: This is because in summer, heaven and earth qi interact, all things grow, damp-heat steams, and birds/insects release toxins. Due to summer heat and sweating, spirit and qi are depleted; one contracts erratic qi from the environment. Thus, suppression methods can also stop it, which is referred to as "shifting spirit and changing qi." However, ancients stated malaria should not be considered Spleen Cold precisely to prevent people from exclusively focusing on warming the spleen, failing to understand the source of creation, and missing the essentials of pathogenesis and qi suitability.