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Yudu poison (Fish-belly Poison) arises on the calf muscle, belonging to the Foot Shaoyin and Foot Taiyang meridians. In the initial stage, it presents with aversion to cold accompanied by high fever (Zenghan Zhuangre), irritability, and localized induration, swelling, and pain. This is caused by a pre-existing deficiency of the Kidney meridian and the downward pouring of damp-heat from the Bladder meridian. It is appropriate to administer formulas that clear and drain damp-heat, cool the blood, and harmonize the Ying (Nutritive) level. Once suppuration occurs, it should be punctured immediately to prevent the spread of toxic heat, which would otherwise lead to prolonged non-healing of the wound; if the patient is deficient, tonifying agents should be used to expel the toxin.

If the calf exhibits diffuse swelling, hardness, sinking depression, purple-dark discoloration, and pain, it is named Feiju (Calf Carbuncle). After ulceration, the discharge of thick pus mixed with blood indicates a favorable prognosis (Shun), whereas the discharge of clear water indicates an unfavorable prognosis (Xiong). In the initial stage, Xianfang Huoming Yin (Immortal Life Elixir) or Bixie Huadu Tang (Dioscorea Hypoglauca Decoction for Resolving Toxins) may be taken; after ulceration, Bazhen Tang (Eight-Treasure Decoction) or Shiquan Dabu Tang (Ten Complete Great Tonification Decoction) are suitable to tonify Qi and Blood.

Huiqiu Yong (Yellow Eel Abscess) arises on the medial side of the calf, also known as Jingyin Ju (Tibia-Yin Carbuncle), resulting from the coagulation of damp-heat in the Liver and Spleen meridians. The area is slightly red and swollen, hard as stone, approximately 3–4 cun in size, with unbearable pain. If it ulcerates as scheduled and discharges thick pus, it is auspicious; if it discharges foul water resembling spoiled sauce, it is ominous. The treatment is the same as for general abscesses and carbuncles.

Fuyin Ju (Foot-Yin Carbuncle) arises three cun above the medial malleolus. Initially, small blisters appear, with pain increasing daily. The area becomes hard, red, and swollen, gradually enlarging to the size of a chicken egg, and upon rupture, bleeds bloody fluid. This is caused by the accumulation of damp-heat at the intersection of the Three Yin meridians. The treatment is the same as for general abscesses and carbuncles. However, Sanyinjiao (SP6) is a point of pure Yin nature, where convergence is slow; therefore, regulation must be handled with caution.

Jiegu Fa (Bone-Fusing Nodule) arises below the calf, at the junction of the tibia and the calcaneus, hence its name. This results from the coagulation of damp-heat in the Bladder meridian. Initially, it resembles a walnut, being hard and diffusely swollen, with red coloration, acute distension, and slight pain. Suppuration should occur rapidly; if delayed, the pus and toxins will damage the sinews. Once the sinews are injured, the leg loses the ability to walk using the heel. "Heel-walking" refers to the inability to place the entire sole flat on the ground, relying solely on the toes for weight-bearing. The treatment is the same as for general abscesses and carbuncles.

(Attachment: Chuangui Tan, Luyan Du)

Waihui Ju (Lateral Malleolus Carbuncle), also known as Jiaogai Du, commonly called Chuangui Du, belongs to the collaterals of the Foot Yangming, Foot Taiyang, and Foot Shaoyang meridians. It is caused by the downward pouring of damp-heat, leading to blood stasis and Qi stagnation. In the initial stage, there is swelling of the lateral malleolus, pain penetrating to the bone, difficulty in movement, and alternating chills and fever. If there is a red halo, Jingfang Baidu San (Aucklandia and Saposhnikovia Powder to Defeat Toxins) with added Niuxi (Achyranthes Root) is appropriate. Once the pus is ripe, it should be punctured, followed by the application of supportive and tonifying methods. If the skin color remains unchanged with diffuse swelling and no head, this is named Chuangui Tan (Lateral Malleolus Phlegm), caused by the deficiency of the Three Yin meridians and the accumulation of cold-dampness obstructing the collaterals; it occurs in young children due to congenital and acquired insufficiency. In the initial stage, warming and unblocking methods are indicated; after ulceration, supportive and tonifying methods are used. However, since this condition is deficient in nature, rapid efficacy is often difficult to achieve.

Neihui Ju (Medial Malleolus Carbuncle) arises near the ankle joint on the medial side of both feet, belonging to the collaterals of the Foot Three Yin meridians. Some cases result from the downward pouring of damp-heat, while others result from the coagulation of cold-dampness. The clinical presentation is similar to the aforementioned conditions, and the treatment methods can be generally applied. In cases where swelling is severe and spreads to the lateral malleolus, followed by ulceration and rotting like sores, with surrounding purple-black discoloration, frequent discharge of toxic fluid, or oozing of foul-smelling pus, it is named Luyan Du (Donkey-Eye Poison), commonly known as Jiagun Chuang (Clamping Stick Sore). This is caused by the flow and stagnation of damp-toxin from the Spleen meridian. It may also arise from traumatic injury or bites from poisonous mosquitoes, midges, or fleas, making it difficult to heal. External application of Zhenzhu San (Pearl Powder) and Bayu Gao (White Jade Ointment) is recommended, along with internal administration of Bixie Huadu Tang (Dioscorea Hypoglauca Decoction for Resolving Toxins), Wuling San (Five-Ingredient Powder with Poria), or Simiao Wan (Four Marvels Pill).