黄连（一两） 吴茱萸（酒浸，逗炒） 山羊肝（一具炙干 蜜丸）
肝者，将军之官。双睛，其外阃也。自衰贼盛，皆能乱其谋虑，故肝病目亦病焉。世人至死而光不灭者，邪
未害其空窍，所谓病一不病二也。然既曰肝病，奈何用黄连苦以泻心？盖心，肝子也。子食母气，火泄木元而肝
弗实矣。且木实，金当平之，心火退则金无所畏，自足以平肝。故曰抑青。用羊肝者，羊啖百草，清净无毒，取
其同类，导引黄连之性入肝。火从寒化，热郁顿解。古人制方曲尽匠心，兹可见其大概。一法以羊胆和蜜熬膏，
且点且服，理亦同。
人参 黄芩 黄连 白僵蚕 鼠粘子 柴胡 连翘 升麻 橘红 板蓝根 元参 桔梗 甘草梢 马屁勃
薄荷
泰和二年，民多疫疠。初觉憎寒体重，次壮热头面肿盛，目不能开，喉舌干渴而喘。俗云大头伤寒。染之多
不救，亲戚不相访问。东垣曰∶身半以上，天之气也。身半以
下，地之气也。此天元气薄，客邪乘之，上攻头目而为病。乃立是方，为细末，姜汤调，时时呷之。余用蜜丸，
中夜噙化，人活甚众。盖连翘、薄荷、元参、板蓝根、鼠、马、蚕、橘，皆清喉利膈之物，虽多无碍。升麻主降
浊，甘草缓之。柴胡主升清，桔梗载之，使气味浮而不沉，自可徐徐宣力。再有人参辅主，芩连逐容，则热邪不
得复居其位，活人宜矣。倘血热便秘，加桃仁、大黄以下血。渴肉 ，加防风、芎、归而行。肿势甚者，须按穴
砭刺，此尽肿胀之治。目如蚌合，如杯覆者，皆可类推。
诗曰∶普济黄连桔薄荷，翘芩元草板蓝和，升柴马勃鼠粘橘，加入蚕参疫奈何。
[Formula: Yi Qing Wan (Suppressing Cyan Pill)]
Coptidis Rhizoma (30 g)
Evodiae Fructus (soaked in wine, lightly stir-fried)
Caprae Hircus Hepatis Siccata (one liver, roasted dry, prepared as honeyed pills)
The Liver is the official of the General. The two eyes are its external gateways. When righteous Qi declines and pathogenic factors flourish, they can all disrupt its strategic planning; therefore, when the Liver is diseased, the eyes also become diseased. Those among the people whose gaze remains bright until death have not had their pathogenic factors invade their hollow orifices; this is referred to as "disease affecting one part but not another." Since it is stated as a Liver disease, why use Coptidis Rhizoma (Huanglian), which is bitter and drains Heart Fire? This is because the Heart is the child organ of the Liver. The child consumes the mother's Qi; draining Heart Fire allows the Wood element (Liver) to be solidified and no longer hyperactive. Furthermore, when Wood is excessive, Metal should regulate it. When Heart Fire recedes, Metal has nothing to fear and is naturally sufficient to level the Liver Wood. Hence, it is called "Yi Qing" (Suppressing Cyan/Liver). Sheep liver is used because sheep graze on various herbs, possessing a pure and non-toxic nature. By taking the principle of similar species attracting each other, it guides the properties of Coptidis Rhizoma into the Liver. Fire transforms through cold, and stagnant heat is suddenly resolved. The ingenuity of ancient physicians in formulating prescriptions can be seen generally here. Another method involves using Gallbladder of Caprae Hircus mixed with honey to make a paste, applied topically to the eyes and taken orally; the rationale is the same.
[Formula: Pu Ji Xiao Du Yin (Universal Benefit Decoction for Eliminating Toxins)]
Ginseng Radix et Rhizoma
Scutellariae Radix
Coptidis Rhizoma
Bombyx Batryticatus
Arctii Fructus
Bupleuri Radix
Forsythiae Fructum
Bupleuri Radix (Note: Text lists Chai Hu and Sheng Ma separately, usually Bupleuri is Chai Hu) -> Correction: Shengma Rhizoma
Citri Reticulatae Pericarpium
Isatidis Radix
Scrophulariae Radix
Platycodonis Radix
Glycyrrhizae Radix et Rhizoma (tip portion)
Lasiosphaeria (Ma Bo)
Menthae Haplocalycis Herba
In the second year of Taihe (1202 AD), an epidemic plagued the populace. Initially, patients felt aversion to cold and heaviness of the body, followed by high fever, severe swelling of the head and face, inability to open the eyes, dryness and thirst of the throat and tongue, and wheezing. Colloquially known as "Big Head Cold Syndrome" (Da Tou Shang Han). Most infected individuals could not be saved, and relatives dared not visit each other. Li Dongyuan said: The upper half of the body is governed by Heaven's Qi; the lower half is governed by Earth's Qi. Here, the primordial Qi of Heaven was weak, allowing exogenous pathogens to take advantage and attack upwards, causing disease in the head and eyes. Thus, he established this formula, ground into fine powder, adjusted with ginger decoction, and sipped frequently. I prepared it as honeyed pills, held in the mouth to dissolve at midnight, saving many lives. Forsythiae Fructum, Menthae Haplocalycis Herba, Scrophulariae Radix, Isatidis Radix, Arctii Fructus, Lasiosphaeria, Bombyx Batryticatus, and Citri Reticulatae Pericarpium are all substances that clear the throat and benefit the diaphragm; even in large doses, they cause no harm. Shengma Rhizoma primarily descends turbidity, while Glycyrrhizae Radix et Rhizoma moderates the action. Bupleuri Radix primarily ascends clarity, and Platycodonis Radix carries the medicinal qi, ensuring the flavors float rather than sink, thus gradually exerting their dispersing power. Additionally, Ginseng Radix et Rhizoma assists the principal agents, while Scutellariae Radix and Coptidis Rhizoma drive out residual heat, so that pathogenic heat cannot reoccupy its position, making recovery likely. If there is blood-heat with constipation, add Persicae Semen and Rhei Radix et Rhizoma to purge blood stasis. If there is muscle rot/ulceration, add Saposhnikoviae Radix, Ligustici Chuanxiong Rhizoma, and Angelicae Sinensis Radix to promote circulation. If swelling is severe, needle-pricking according to acupoints is required; this covers the treatment of swelling. Conditions where the eyes are closed like a clam shell or covered like an inverted cup can be inferred analogously.
Poem states: Pu Ji Xiao Du Yin contains Huanglian, Jiegeng, Bohe, Qiaoxin, Yuancao, Banlangen harmonized together; Shengchai, Mabo, Niuzao, Ju, plus Can and Renshen, addressing epidemics helplessly (implying efficacy against such dire conditions).