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Regarding diseases affecting conception, in men it lies in the Jing (Essence), and in women it lies in the Blood; both are essentially due to deficiency. In men, deficiencies may manifest as seminal emission (slippage of essence), clear semen, or cold semen, or hardness failure during intercourse, or flow without ejaculation, or frequent nocturnal emissions, or turbid urine with dribbling and dysuria, or excessive lust for women leading to Yin Deficiency, which causes soreness and fatigue in the lower back and kidneys; or preference for male homosexuality leading to Extreme Yang, where Hyperactivity results in exhaustion and death. If Yin is excessively strong and solid, it leads to disharmony between victory and defeat; or if one suffers from Yin Hernia (Yin Han) chronically, it causes a separation between the Liver and Kidney. Additionally, some suffer from Yang Decline, resulting in excessive cold; others suffer from Yin Deficiency, resulting in excessive heat. These are all diseases of men and cannot be entirely blamed on women. If the root cause is identified and treated, success is assured.

In women, treatment focuses on the Blood, as the Blood combines with Essence to form the fetus. To observe her pathology, one must look at the Menstrual Cycle (Jing Hou); to treat it, one must regulate the Yin aspect. The Menses are Blood, and Blood is Yin. Yin corresponds to the moon, hence the regular monthly arrival, which is the norm. When pathological, menstruation may occur early or late, twice a month, once every two months, cease completely, or continue incessantly; it may involve pain before flow or pain after flow; the color may be pale, purple, or black; clots may form strips or pieces; insufficient Jing and Blood may transform into leukorrhea and turbidity; sinking of Yuan Qi may transform into metrorrhagia and metrostaxis (Beng Lou); uterine deficiency-cold may prevent the transformation and generation by Yang Qi; latent heat in the Blood may prevent the condensation of Yin Qi; blood and qi masses (Jia) may cause the uterus to fail to contract and menstruation to stop. All these are diseases of True Yin (the main treatment methods are detailed in the volumes on Regulating the Menses). Once True Yin is diseased, those with insufficient Yin Blood cannot nourish the fetus, and those with insufficient Yin Qi cannot grasp the fetus. The authority over grasping and nourishing lies entirely in the Mingmen (Gate of Life), as Mingmen is the Sea of Blood for the Chong and Ren vessels. The fetus is primarily sustained by Blood, but Blood cannot generate itself and relies on Qi as its master; this is referred to as True Yin. Therefore, tonifying Mingmen, whether by Qi or Blood, can be called tonifying Yin. The method of tonifying Yin is the way of nurturing the root and consolidating the foundation. This is indispensable from youth to old age for everyone, let alone as the foundation of congenital and acquired constitution; without exerting effort here, there is no way to succeed. Thus, the methods of regulating the menses and promoting conception focus mainly on filling Mingmen and cherishing Yang Qi. However, the hub of Jing and Blood is in Mingmen, while the source of Jing and Blood lies between the Heart and Spleen (referred to as "Er Yang" in the text, contextually implying the heart-spleen axis for blood/qi generation). The Heart governs Blood; nourishing the Heart nourishes the Blood. The Spleen and Stomach govern digestion; strengthening them allows Qi to distribute. When both are harmonious, Qi flows smoothly and Blood circulates. Emotional state and diet should be planned for prior to addressing menstrual blood, all aiming to supplement the source of Yin. If one does not understand the root and branch, priority and sequence, and treats blindly, how can one speak of the methods for regulating the menses and promoting conception?