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Wei Qi (Defensive Qi) converges at the Fengfu point (GV16) once every day and night. At this time, the Cou Li (skin texture and pores) open; when the Cou Li open, pathogenic factors enter, and upon entry, the disease manifests. At that moment, Yin and Yang Qi contend with each other, shifting according to their respective strengths, thus generating alternating chills and fever. Consequently, the onset of symptoms varies in timing. If the Zang-Fu organs are invaded by pathogens, internal and external defenses fail, and pathogenic factors act recklessly, resulting in irregular intervals between symptom episodes.

Malaria is caused by damage from summerheat and wind. During periods of intense heat, excessive sweating, vomiting, or purging can lead to emptiness in the Zang-Fu organs and damage to Ying Qi (Nutritive Qi) and Wei Qi (Defensive Qi). Pathogenic factors then lie dormant, causing the illness to persist for a long time without recovery, yet still recurring periodically. Malaria may recur annually; if it persists for three years with frequent attacks lasting months, and a mass forms under the hypochondrium, treatment should not directly attack the mass but rather deplete the body fluids. Induce sweating before the onset of an attack. After taking the decoction, if the patient initially feels slightly cold, they should cover themselves with clothing to warm up and induce sweating, allowing urination to flow freely.

Patients with Jaundice suffer from generalized body pain, fever, and a deep yellow complexion. After seven or eight days, intense heat accumulates internally, and there is a method to purge blood stasis, resembling liver pathology. The patient experiences urgency and tightness in the lower abdomen.
If the patient has sore, gritty eyes, pain in the nasal bone, stiffness in both arms and the neck, and tightness in the waist and back, they are suffering from Jaundice. Stool is often dry and difficult to pass; ensuring smooth urination prevents death. Frequent bowel movements are not necessary; excessive frequency leads to abdominal distension and fullness. This condition arises from cold-dampness lingering on the exterior, causing heat to accumulate in the Spleen and Stomach. With the Cou Li closed, stagnant heat combats retained food, causing vexation and stagnation that cannot be resolved, leading to obstruction of both stool and urine. Thus, the body and face turn yellow.
In all cases of Jaundice, if the Cun Kou pulse (radial artery near the wrist crease) is imperceptible near the palm, and cold air emanates from the mouth and nose, the condition is incurable.

Heat in the Spleen and Stomach causes grain qi to stagnate and steam. Combined with the addition of toxic heat, sudden jaundice occurs, accompanied by chest fullness and panting, with life hanging in the balance; hence it is called Ji Huang (Acute Jaundice). Some patients develop immediate yellowing of the body and face upon falling ill, while others do not realize they have Jaundice until after death. A symptom pattern characterized solely by fever and mental tremors indicates Acute Jaundice.

The disease known as Huang Han (Yellow Sweat) presents with severe edema of the body, fever, sweating without thirst, and symptoms resembling Feng Shui (Wind-Water edema). The sweat stains clothes yellow, resembling cypress sap, and the pulse is deep. This results from heat in the Spleen and Stomach combined with bathing in water while sweating; if water enters through the pores, Yellow Sweat is formed.