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Zhu Danxi stated: The *Neijing* (Classic of Internal Medicine) asserts that all types of Wei syndrome (flaccidity syndrome) originate from Lung heat, and further states that in treating Wei syndrome, one should exclusively focus on the Yangming meridians. This is because the Lung belongs to Metal, has a dry nature, governs Qi, and fears Fire; the Spleen belongs to Earth, has a damp nature, governs the four limbs, and fears Wood. If desires are unrestrained, Kidney Water loses its nourishment, causing Fire to lack restraint and overact upon its controlled element (Metal), leading to Heat in the Lung due to Fire pathogen invasion. When the Lung is heated, Metal loses nourishment, causing Wood to lack restraint and overact upon its controlled element (Earth), injuring the Spleen due to Wood pathogen invasion. Lung Heat prevents the regulation of the whole body, and Spleen injury renders the four limbs unusable, thus giving rise to various Wei syndromes. By draining the South (Heart/Fire), Lung Metal becomes clear, and East Liver/Wood does not become excessive; how could the Spleen be injured? By tonifying the North (Kidney/Water), Heart Fire descends, and West Lung/Metal does not become deficient; how could Lung Heat exist? Therefore, when the Yangming channels are full, the Zongjin (major tendons) are moistened, enabling them to bind the bones and facilitate joint movement.

Naturally produced foods tend to be Yang in nature, and rich flavors generate Heat. For those suffering from Wei syndrome, diet must be bland. In cases where food intake is low, muscles are emaciated, or diarrhea occurs, even if there is internal Heat, priority must be given to restoring Stomach Qi using aromatic and sweet-warm herbs. Once appetite improves, the flaccidity will naturally strengthen. If one rigidly adheres to cold-cooling remedies, Grain Qi will further decline, and the extremities will become increasingly withered.

In Damp-Heat Wei syndrome, rain-dampness invades, pathogens steam and damage the Spleen, flowing into the four limbs. Patients feel counter-flowing Qi rising from the calves, or experience soreness, softness, swelling, and pain in the four limbs, or numbness and stubborn itching in the toes. Urine is red and scanty, and the pulse is deep, soggy, and rapid. These are all caused by Damp-Heat in the lower jiao. As it is said: "If Damp-Heat is not dispelled, the large sinews shorten, and the small sinews elongate." Shortening of large sinews leads to contracture, while elongation of small sinews leads to flaccidity. The appropriate treatment is to raise Yang and dry Dampness; filling and cloying agents should be strictly avoided.

In Damp-Phlegm Wei syndrome, this condition is common in obese individuals where Damp-Phlegm stagnates internally, lodging in the meridians, causing numbness in the waist and knees, and flaccidity in the four limbs. The pulse is deep and slippery. This results from rich food and alcohol-dampness. The appropriate treatment is to dry the Spleen and resolve Phlegm.

In Qi-deficiency Wei syndrome, it arises from hunger and fatigue, causing the entire body's sinews and joints to lose nourishment. Thus, the Zongjin becomes lax, and bone joints feel empty. All cases of post-illness flaccidity in hands and feet belong to Qi deficiency. This refers to the concept that "when the Spleen is diseased, it cannot transport fluids for the Stomach, and the four limbs do not receive water and grain Qi, rendering them useless." The appropriate treatment is Bu Zhong Yi Qi Tang (Tonify the Middle and Augment the Qi Decoction). "Treating Wei syndrome by exclusively focusing on Yangming" establishes the principle for Qi-deficiency cases.

In Yin-deficiency Wei syndrome, it results from excessive drinking and sexual indulgence, causing Fire in the Lower Jiao (Liver and Kidneys) to scorch the sinews and bones. Patients feel extreme heat in both feet rushing upward to the legs, with soreness, weakness, and flaccidity in the knees, making walking difficult. The pulse is choppy and weak, or the left pulse may appear large but feels powerless upon pressure. The appropriate treatment is to nourish the Liver and Kidneys.

In Blood-deficiency Wei syndrome, it commonly occurs after childbirth or blood loss, presenting with sallow complexion, weakness in hands and feet, and inability to move. The appropriate treatment is to nourish Ying-Blood. Often, Wei syndrome persists despite the use of Blood-nourishing herbs because the Spleen is too deficient to generate Blood.

In Blood-stasis Wei syndrome, symptoms include pain in the four limbs preventing movement, resulting in a choppy and hollow pulse. The appropriate treatment is to nourish Blood and move stasis.

In Food-stagnation Wei syndrome, it is caused by excessive eating, disrupting ascending and descending functions, so Spleen Qi cannot transport nutrients to the four limbs. Symptoms include weakness in hands and feet, abdominal distension and pain, nausea, and belching. The appropriate treatment is to guide out food stagnation, followed by tonifying the Spleen.

After dysentery, if there is leg weakness, calf pain, or knee swelling, it is caused by excessive downward purging leading to Yin exhaustion. The appropriate treatment is to tonify the Spleen combined with lifting agents. Occasionally, if astringents were used too early during dysentery, causing retained accumulation and stasis to flow down into the collaterals and form Wei syndrome, the treatment should involve moving Qi and expelling stasis, which is completely different from the previous conditions.