(俱徐灵胎着。灵胎名大椿。江苏吴江人也。)
方药离合论
方之与药。似合而实离也。得天地之气。成一物之性。各有功能。可以变易血气。以除
疾病。此药之力也。然草木之性。与人殊体。入人肠胃。何以能如人之所欲以致其效。圣人
为之制方以调剂之。或用以专攻。或用以兼治。或相辅者。或相反者。或相用者。或相制者。
故
夫按病用药。药虽切
有一二味与病不相关者。谓之有方无药。譬之作书之法。用笔已工而配合颠倒。与夫字形俱
备而点画不成者。皆不得谓之能书。故善医者。分观之而无药弗切于病情。合观之而无方不
本于古法。然后用而弗
则亦同于杀人而已矣。至于方之大小奇偶之法。则内经详言之。兹不复赘云。
古方加减论
古人制方之义。微妙精详。不可思议。盖其审察病情。辨别经络。参考药性。斟酌轻重。
其于所治之病不爽毫发。故不必有奇品异术。而沉痼艰险之疾。投之辄有神效。此汉以前之
方也。但生民之疾病不可胜穷。若必每病制一方。是曷有尽期乎。故古人即有加减之法。其
病大端相同。而所现之症或不同。则不必更立一方。即于是方之内。因其现症之异。而为
加减。如伤寒论中治太阳病用桂枝汤。若见项背强者。则用桂枝加葛根汤。喘者。则用桂枝
加浓朴杏仁汤。下后脉促胸满者。桂枝去白芍汤。更恶寒者。去白芍加附子汤。此犹以药为
加减者也。若桂枝麻黄各半汤。则以两方为加减矣。若发奔豚者。用桂枝为加桂枝汤。则又
以药之轻重为加减矣。然一二味加减。虽不易本方之名。而必明着其加减之药。若桂枝汤倍
用芍药而加饴糖。则又不名桂枝加饴糖汤而为建中汤。其药虽同而义已别。则立名亦异。古
法之严如此。后之医者不识此义。而又欲托名用古。取古方中一二味。则即以某方目之。如
用柴胡则即曰小柴胡汤。不知小柴胡之力全在人参也。用猪苓、泽泻即曰五苓散。不知五苓
之妙专在桂枝也。去其要药。杂以他药。而仍以某方目之。用而不效。不知自咎。或则归咎
于病。或则归咎于药。以为古方不可治今病。嗟乎。即使果识其病。而用古方支离零乱。岂
有效乎。遂相戒以为古方难用。不知全失古方之精义。故与病毫无益而反有害也。然则当何
如。曰。能识病情与古方合者。则全用之。有别症。则据古法加减之。如不尽合。则根据古方
之法。将古方所用之药而去。取损益之。必使无一药之不对症。自然不倍于古人之法。而所
投必有神效矣。
方剂古今论
后世之方。已不知几亿万矣。此皆不足以名方者也。昔者圣人之制方也。推药理之本原。
识药性之专能。察气味之从逆。审脏腑之好恶。合君臣之配偶。而又探索病源。推求经络。
其思远。其义精。味不过三四。而其用变化无穷。圣人之智。真与天地同体。非人之心思所
能及也。上古至今。千圣相传。无敢失坠。至张仲景先生。复申明用法。设为问难。注明主
治之症。其伤寒论、金匮要略。集千圣之大成以承先而启后。万世不能出其范围。此之谓古
方。与内经并垂不朽者。其前后名家如仓公、扁鹊、华佗、孙思邈诸人。各有师承。而渊源
又与仲景微别。然犹自成一家。但不能与灵、素、本草一线相传。为宗支正脉耳。既而积习
相仍。每着一书。必自撰方千百。唐时诸公。用药虽博。已乏化机。至于宋人。并不知药。
其方亦板实肤浅。元时号称极盛。各立门庭。徒骋私见。迨乎前明。蹈袭元人绪余而已。
今之医者。动云古方。不知古方之称。其指不一。若谓上古之方。则自仲景先生流传以外。
无几也。如谓宋元所制之方。则其可法可传者绝少。不合法而荒谬者甚多。岂可奉为典章。
若谓自明人以前皆称古方。则其方不下数百万。夫常用之药不过数百品。而为方数百万。随
拈几味。皆已成方。何必定云某方也。嗟嗟。古之方何其严。今之方何其易。其间亦有奇巧
之法。用药之妙。未必不能补古人之所未及可备参考者。然其大经大法。则万不能及。其中
更有违经背法之方。反足贻害。安得有学之士。为之择而存之。集其大成。删其无当。实千
古之盛举。余盖有志而未遑矣。
古今方剂大小论
今之论古方者。皆以古方分两太重为疑。以为古人气体浓。故用药宜重。不知此乃不考
古而为此无稽之谈也。古时升斗权衡。历代各有异同。而三代至汉。较之今日。仅十之二。
(余亲见汉时有六升铜量。容今之一升二合。)如桂枝汤乃伤寒大剂也。桂枝三两。芍药三
两。甘草二两。共八两。二八不过一两六钱为一剂。分作三服。则一服药不过今之五钱三分
零。他方间有药品多而加重者。亦不过倍之而已。今人用药。必十数品。各一二钱。或三四
钱。则反用三两外矣。更有无知妄人。用四五两作一剂。近人更有用熟地八两为一剂者。尤
属不伦。用丸散亦然。如古方乌梅丸。每服如桐子大二十丸。今不过四五分。若今人之服丸
药。则用三四钱至七八钱不等矣。末药只用方寸匕。不过今之六七分。今亦服三四钱矣。古
人之用药分两。未尝重于今日。(周礼遗人。凡万民之食食者人四釜。注。六斗四升曰釜。
四釜共二石五斗六升。为人一月之食。则每日食八升有余矣。)而谬说相传。方剂日重。
此一端。而荒唐若此。况其深微者乎。盖既不能思考古。又无名师传授。无怪乎每举
谈也。
煎药法论
煎药之法。最宜深讲。药之效不效。全在乎此。夫烹饪禽鱼羊豕。失其调度。尚能损人。
况
然后加余药同煎。此主药当先煎之法也。而桂枝汤又不必先煎桂枝。服药后须啜热粥以助药
力。又一法也。如茯苓桂枝甘草大枣汤则以甘澜水先煎茯苓。如五苓散则以白饮和服。服后
又当多饮暖水。小建中汤则先煎五味去渣而后纳饴糖。大柴胡汤则煎减半去渣再煎。柴胡加
龙骨
二十沸。煎药之法。不可胜数。皆各有意义。大都发散之药及芳香之药不宜多煎。取其生而
疏泄。补益滋腻之药宜多煎。取其熟而停蓄。此其总诀也。故方药虽中病。而煎法失度。其
药
难愈也。若今之医者。亦不能知之矣。况病家乎。
服药法论
病之愈不愈。不但方必中病。方虽中病而服之不得其法。则非特无功。而反有害。此不
可不知也。如发散之剂。欲驱风寒出之于外。必热服而暖覆其体。令药气行于营卫。热气周
遍。挟风寒而从汗解。若半温而饮之。仍当风坐立。或仅寂然安卧。则药留肠胃。不能得汗。
风寒无暗消之理。而营气反为风药所伤矣。通利之药。欲其化积滞而达之于下也。必空腹顿
服。使药性鼓动。推其垢浊从大便解。若与饮食杂投。则新旧混杂。而药气与食物相乱。则
气性不专而食积愈顽矣。故伤寒论等书服药之法。宜热。宜温。宜凉。宜冷。宜缓。宜急。
宜多。宜少。宜早。宜晚。宜饱。宜饥。更有宜汤不宜散。宜散不宜丸。宜膏不宜丸。其轻
重大小上下表里。治法各有所当。此皆一定之至理。深思其义。必有得于心也。
(All from the works of Xu Lingtai. Xu Lingtai, whose given name was Dachun, was a native of Wujiang, Jiangsu.)
On the Combination and Separation of Formulas and Herbs
Formulas (Fangji) and herbs (Yaowu) appear combined but are essentially distinct. Herbs absorb the Qi of Heaven and Earth, forming their unique natures, each possessing specific functions capable of altering the flow of Blood and Qi in the body to eliminate disease. This is the power of herbs. However, the nature of herbs differs from the human constitution. Upon entering the stomach and intestines, how can they act according to one's will to achieve efficacy? The Sages formulated formulas to regulate them. Some formulas are used for targeted attack, some for concurrent treatment of multiple conditions, some with herbs that assist each other, some that constrain each other, some that utilize each other, and some that suppress each other. Therefore, when prescribing based on the condition, even if the herbs are appropriate, if one or two herbs in the formula are irrelevant to the pathology, it is called "having a formula without proper herbs." This is like calligraphy: even if the brushwork is skilled, if the structure is inverted, or if the character forms are complete but the strokes are malformed, it cannot be called proficient writing. Thus, a skilled physician, viewing individual herbs, ensures none deviate from the pathology; viewing the whole formula, ensures no formula departs from ancient methods. Only then can they be applied; otherwise, it amounts to killing people. As for the methods regarding the size and odd/even combinations of formulas, these are detailed in the *Huangdi Neijing* (Yellow Emperor's Inner Canon), so there is no need to repeat them here.
On the Addition and Subtraction of Ancient Formulas
The intent behind the ancients' formulation of prescriptions was subtle, profound, and inconceivable. They carefully examined the pathology, differentiated the meridians, referenced herb properties, and weighed the dosages. Their accuracy regarding the treated diseases was impeccable. Thus, they did not need rare items or exotic techniques, yet stubborn and dangerous diseases often responded miraculously to these treatments. These were the formulas before the Han Dynasty. However, the diseases of the people are infinite. If a separate formula were created for every disease, when would it end? Therefore, the ancients employed the method of addition and subtraction. If the general nature of the disease is the same but the manifested symptoms differ, there is no need to establish a new formula. Instead, within the existing formula, adjustments are made based on the differing symptoms. For example, in the *Shanghan Lun* (Treatise on Cold Damage), Guizhi Tang (Cinnamon Twig Decoction) is used for Taiyang disease. If neck and back stiffness appears, Guizhi Jia Gegen Tang (Cinnamon Twig Decoction plus Pueraria Decoction) is used. If wheezing occurs, Guizhi Jia Houpo Xingren Tang (Cinnamon Twig Decoction plus Magnolia Bark and Apricot Kernel Decoction) is used. After purgative therapy, if rapid pulse and chest fullness appear, Guizhi Qu Shaoyao Tang (Cinnamon Twig Decoction minus Peony Root Decoction) is used. If aversion to cold worsens, Shaoyao is removed and Fuzi Tang (Aconite Decoction) is added. This is still adding or subtracting single herbs. If Guizhi Mahuang Ban Ge Tang (Half-and-Half Cinnamon Twig and Ephedra Decoction) is used, it involves combining two formulas. If treating Ben Tun (Running Piglet syndrome), using Guizhi Tang with increased dosage of Guizhi (Cinnamon Twig) represents adjustment by weight. However, adding or subtracting one or two herbs usually retains the original formula's name but must explicitly state the added or subtracted herbs. If Shaoyao (Peony Root) is doubled in Guizhi Tang and Yi Tang (Maltose) is added, it is no longer called Guizhi Jia Yitang Tang but Jianzhong Tang (Middle-Building Decoction). Although the herbs are similar, the meaning has changed, so the name differs. The rigor of ancient methods was such. Later physicians, failing to understand this principle yet wishing to borrow the prestige of ancient formulas, would take one or two herbs from an ancient formula and label it as that formula. For instance, using Chaihu (Bupleurum Root) and calling it Xiao Chaihu Tang (Minor Bupleurum Decoction), unaware that the efficacy of Xiao Chaihu Tang lies entirely in Renshen (Ginseng Root); using Zhuling (Polyporus) and Zexie (Alisma Rhizome) and calling it Wuling San (Five-Ingredient Powder with Poria), unaware that the subtlety of Wuling San lies entirely in Guizhi (Cinnamon Twig). Removing key herbs, mixing in others, yet still labeling it as a specific formula, results in inefficacy. Not blaming themselves, they blame the disease or the herbs, claiming ancient formulas cannot treat modern diseases. Alas! Even if the disease is correctly identified, using fragmented and disjointed ancient formulas cannot yield efficacy. Consequently, people warn that ancient formulas are difficult to use, completely missing the essence of ancient formulas, thus being not only useless but harmful. So, what should be done? One should say: If the pathology matches an ancient formula, use it entirely. If there are additional symptoms, apply additions and subtractions according to ancient methods. If it does not fully match, follow the principles of ancient formulas: remove inappropriate herbs from the ancient formula, retain beneficial ones, and discard harmful ones, ensuring every herb corresponds to the symptoms. Naturally, this will not violate ancient methods, and the prescription will yield miraculous effects.
On Ancient and Modern Formulas
Modern formulas number in the hundreds of millions, yet few deserve the title of true formulas. In antiquity, the Sages formulated prescriptions by exploring the origins of pharmacology, recognizing specific herb properties, investigating the compliance or opposition of flavors and aromas, assessing the preferences and aversions of Zang-Fu organs, coordinating the relationships between Sovereign, Minister, Assistant, and Envoy herbs, exploring disease sources, and tracing meridians. Their thinking was far-reaching, and their meanings profound. With merely three or four ingredients, their applications were infinite. The wisdom of the Sages was truly on par with Heaven and Earth, beyond the reach of ordinary human thought. From antiquity to the present, passed down through thousands of sages, never lost or abandoned. It was Mr. Zhang Zhongjing who clarified usage, posed questions and difficulties, and noted indicated symptoms. His *Shanghan Lun* (Treatise on Cold Damage) and *Jingui Yaolue* (Essential Prescriptions of the Golden Cabinet) gathered the achievements of thousands of sages to inherit the past and initiate the future. Ten thousand generations could not exceed its scope. These are called ancient formulas, immortal alongside the *Neijing*. Famous experts before and after him, such as Cang Gong, Bian Que, Hua Tuo, and Sun Simiao, each had their own lineages, slightly different from Zhongjing's, yet still forming their own schools. However, they could not claim direct lineage from the *Lingshu*, *Suwen*, and *Shennong Bencao Jing* as the orthodox branch. Gradually, habits persisted; every book written involved creating hundreds of new formulas. In the Tang Dynasty, although doctors used a wide variety of herbs, they lacked spiritual transformation. By the Song Dynasty, doctors barely understood herbs; their formulas were rigid, solid, and superficial. The Yuan Dynasty boasted great prosperity, with various sects displaying personal views. The Ming Dynasty merely followed Yuan remnants. Today's physicians constantly speak of ancient formulas, not realizing that "ancient formula" refers to different things. If referring to pre-Qin formulas, few exist outside those transmitted by Zhang Zhongjing. If referring to Song and Yuan formulas, very few are worthy of emulation, while many are irregular and absurd; how can they be regarded as canonical? If referring to all formulas before the Ming Dynasty, there are millions. With only hundreds of commonly used herbs, millions of formulas have been created by randomly picking a few ingredients. Why insist on naming them specific formulas? Alas! How rigorous were ancient formulas, and how casual are modern ones. Among them, there are ingenious methods and subtle herb uses that may supplement the ancients' omissions and serve as references. However, their fundamental laws cannot compare to the ancients. Moreover, some formulas violate classics and laws, causing harm. Where are the learned scholars to select and preserve the best, compile the greatest collection, delete the inappropriate, and accomplish this great task for millennia? I have the ambition but lack the time.
On the Size of Ancient and Modern Formulas
Those discussing ancient formulas today suspect that ancient dosages were too heavy, arguing that ancients had robust constitutions and thus required heavier medication. This is baseless talk born of ignoring historical evidence. Measures of volume and weight varied across dynasties. From the Three Dynasties to the Han Dynasty, compared to today, they were only about one-tenth to one-fifth the size. (I have personally seen a Han Dynasty bronze measure of six Sheng, which holds the equivalent of today's 1.2 Sheng.) For example, Guizhi Tang is a large dose for Shanghan. It contains Guizhi (Cinnamon Twig) 3 Liang, Shaoyao (Peony Root) 3 Liang, and Gancao (Licorice Root) 2 Liang, totaling 8 Liang. Eight times eight equals sixty-four, converting to 1.6 Qian as one dose, divided into three servings. Thus, one serving is only about 0.53 Qian in modern terms. Other formulas with more ingredients might double the weight, but rarely exceed this significantly. Modern doctors use over ten herbs, each 1-2 Qian or 3-4 Qian, totaling over 3 Liang per dose. Ignorant fools use 4-5 Liang per dose. Recent practitioners even use 8 Liang of Shudi (Rehmannia Root Preparata) per dose, which is utterly improper. The same applies to pills and powders. For instance, ancient Wumei Wan (Mume Pill) prescribed twenty pills the size of paulownia seeds per dose, whereas today's equivalent is only 4-5 Fen. Modern pill doses range from 3-4 Qian to 7-8 Qian. Powder doses using a square-inch scoop (Fangcunbi) were only 6-7 Fen today, but now people take 3-4 Qian. Ancient dosages were never heavier than today's. (According to *Zhouli*, the food allowance for the people was four Fu per person per month. A Fu is 6.4 Dou. Four Fu total 2.5 Dou 6 Sheng, meaning daily intake was over 8 Sheng.) Yet rumors spread that dosages have increased over time. This absurdity alone suffices; imagine the depth of the error. Lacking the ability to think historically and without master teachers, it is no wonder discussions are so frivolous.
On the Method of Decocting Herbs
The method of decocting herbs deserves deep study. Efficacy depends entirely on this. Improper cooking of poultry, fish, or meat can harm humans, let alone medicinal herbs... [Text gap inferred] ...then add remaining herbs to decoct together. This is the method where sovereign herbs are decocted first. However, Guizhi Tang does not require pre-decocting Guizhi; drinking hot porridge after administration to boost efficacy is another method. For Fuling Guizhi Gancao Dazao Tang (Poria, Cinnamon Twig, Licorice, and Jujube Decoction), Ganlan Shui (Agitated Water) is used to pre-decoct Fuling. For Wuling San, it is taken with rice water, followed by drinking warm water. Xiaojianzhong Tang requires decocting five herbs first, straining, then adding Yitang (Maltose). Dahuang Chaihu Tang is decocted until reduced by half, strained, and then re-decocted. Chaihu Jia Longgu Muli Tang is boiled for twenty boils. There are countless decoction methods, each with specific meanings. Generally, dispersing and aromatic herbs should not be decocted long to preserve their raw, dispersing qualities. Tonifying and cloying herbs should be decocted longer to achieve cooked, accumulating properties. This is the general rule. Thus, even if the formula is correct, improper decoction makes the medicine ineffective in curing the disease. Modern physicians often do not know this, let alone patients.
On the Method of Taking Medicine
Whether a disease is cured depends not only on the formula matching the pathology but also on the method of administration. Even if the formula is correct, improper administration yields no benefit and may cause harm. This must be known. For dispersing agents intended to expel wind-cold externally, they must be taken hot and covered warmly to allow the medicinal Qi to circulate in Ying and Wei, spreading heat to induce sweating and expel wind-cold. If taken lukewarm, sitting in drafts, or lying quietly, the medicine remains in the stomach and intestines, failing to induce sweat. Wind-cold will not dissipate secretly, and Ying Qi will be damaged by the wind-dispersing herbs. For purgative agents intended to resolve stagnation and guide it downward, they must be taken on an empty stomach in one dose to stimulate the medicinal action and push turbidity out via stool. If taken with food, old and new contents mix, medicinal Qi conflicts with food, Qi becomes unfocused, and food stagnation worsens. Therefore, texts like *Shanghan Lun* specify various administration methods: hot, warm, cool, cold, slow, fast, large amount, small amount, early, late, full stomach, empty stomach. Some suit decoctions better than powders, powders better than pills, pastes better than pills. Regarding light/heavy, large/small, upper/lower, exterior/interior, each treatment has its appropriate method. These are fixed truths. Deep contemplation of their meaning will yield understanding.