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Treats severe conditions where Yin-toxic pathogenic factors attack upward, causing abdominal pain and cold extremities (limb reversal).
Take Chuanwu Tou (Aconiti Radix Preparata), remove the skin and navel, soak in cold water for seven days, slice thinly, dry in the sun, and store in a paper bag. When treating a patient, take one qian (approx. 3-5g) of the fine powder, one small qian of salt, add one and a half lamps of water, decoct until reduced to seven-tenths, and administer orally in one dose. This suppresses the Yin-toxin; after defecation, the stool resembles pig's blood. If symptoms persist, administer again after a while.

Treats Yin-toxin presenting with a bluish complexion, cold extremities, mental restlessness, and abdominal pain.
Take Shihuang (Sulfur), prepared as a fine powder.
Mix two qian with fresh well water, wait for a while, or observe if chills or fever arise, then check the pulse for tightness or slackness; recovery occurs when sweating ensues.

A person suffered from Shanghan (Cold Damage) for six or seven days, experiencing mental irritability, drowsiness, frequent vomiting, white urine, and spontaneous sweating. Upon diagnosis, both the Cun (inch) and Chi (cubit) positions of the pulse were tight. I stated: "This is Cold invading the Shaoyin meridian, hence the tight pulse." Zhang Zhongjing said: "When a patient has a tight pulse and sweats, it indicates the loss of Yang Qi (Wangyang)." This belongs to Shaoyin disease; according to the method, it should present with sore throat and diarrhea, which refers to this case. Someone asked: "The tight pulse usually belongs to the 'Seven Superficial Pulses' (Yang pulses), but Zhang Zhongjing associates the tight pulse with Shaoyin. Does the tight pulse belong to Yang pathogens or Yin pathogens?" I replied: "Zhang Zhongjing states that when both Cun and Kou positions are tight, clear pathogens attack the Upper Jiao, and turbid pathogens attack the Lower Jiao. He also said: 'When both Yin and Yang pulses are tight,' symptoms include warm breath from the mouth, dry lips and tongue, fatigue and desire to lie down, cold feet, nasal discharge, and a slippery coating on the tongue; do not treat rashly. He further said: 'Tightness indicates Cold.' And: 'All tight pulses indicate Cold.' Or someone might ask: 'Where does the tight pulse come from?' The Master said: 'If sweating or vomiting has already occurred, due to Cold in the Lung interior, the pulse becomes tight; if coughing occurs because cold water was drunk, the pulse becomes tight; if diarrhea occurs due to Stomach deficiency, the pulse becomes tight.' He also said: 'If the Cun pulse is faint, the Chi pulse is faint, and the Chi pulse is tight, the person suffers from deficiency and excessive sweating.' From this, we see that this is caused by Cold pathogenic qi entering the meridians and collaterals, representing a typical deficiency-cold pulse. If located in Yang meridians, the pulse is floating and tight; if in Yin meridians, the pulse is deep and tight. Thus, Zhang Zhongjing said: 'Floating and tight is named Shanghan.' He also said: 'If the Yangming pulse is floating and tight, tidal fever must occur.' This is the case in Yang, i.e., floating and tight. In Yin, it is deep and tight, so Zhang Zhongjing said: 'If the Cun pulse is faint, the Chi pulse is tight, and after seven or eight days spontaneous diarrhea occurs, the pulse suddenly becomes faint, hands and feet become warm, and the tightness disappears, this indicates the disease is resolving.' This is the case in Yin, i.e., deep and tight. Zhang Zhongjing said: 'Floating indicates exterior, deep indicates interior; rapid indicates Fu organs, slow indicates Zang organs.' To determine interior/exterior and Zang/Fu, first establish based on floating, deep, rapid, and slow, then differentiate Yin and Yang by combining with other pulse characteristics. Therefore, when discussing Shanghan, one must take Zhang Zhongjing's pulse methodology as the standard. Studying Shanghan must be based on Zhang Zhongjing, just as military strategy must be based on Sun Wu and Wu Qi. To abandon this for others is like abandoning compasses and squares to seek perfect shapes, or abandoning musical pitches to tune the five tones; is this acceptable?
The Dansha Wan (Cinnabar Pill) in Huoren (The Living Manual) discusses the mutual entrapment of Yin and Yang toxins. Breaking the Yin toxin merely reveals the Yang pulse hidden within; Yin-hidden-Yang presents as a pulse that appears and disappears deeply (Xi Yan Chen).