《素问》云∶ 疟皆生于风,其蓄作有时,何气使然?夫阴阳上下交争,虚实相移也。
阳并于阴,阴实阳虚,寒栗鼓颔。此皆夏伤于暑,热气藏于皮肤之内,肠胃之外。腠理开,
得秋气,汗出遇风,得之与卫气并。卫气昼行阳,夜行阴,气得阳外出,得阴内薄,外内
相薄,是以日作也。其有间日者,气深,内薄于阴,阳气独发,阴邪内着,阴与阳争不得出,
是以间日作也。其作晏与早者,邪气客于风府,循膂而下,卫气一日一夜大会于风府,其日
下一节,先
客于脊背,每至风府则腠理开,腠理开则邪气入,则病作晏也。
夫寒者阴气也,热者阳气也,先伤寒而后伤风,故先寒而后热,名曰寒疟。先伤于风,后
伤寒,故先热而后寒,名曰温疟。其但热而不寒者,阴气先绝,阳气独胜,少气烦冤,手足
热,欲呕,名曰痹疟。
有余则泻,不足补。热为有余,寒为不足。寒已得火不能温,热已冰水不能凉。阴胜并
于阳,阳胜并于阴,阴胜则寒,阳胜则热。故疟者,阴阳风寒虚实邪气不常之所作也。
辟邪丹 治岚瘴鬼疟食疟并月频日者。
绿豆 雄黑豆(各四十九粒) 信砒(半钱,别研) 黄丹(一钱,为衣) 朱砂(二钱)
上为末,同入乳钵内,滴水为丸,分作三十粒,每服一粒,已用东南桃心,取七枝,研
汁,将井花水早辰日出不出,向日吞之,醋汤亦得。已发日服。
斩邪丹 治诸般疟疾无时不止者。
绿豆 小豆(各三十粒,口退皮再入) 朱砂 信砒(各一钱)
上为末,同研细,滴水和丸,匀分作十丸,每服一丸,已早辰服,夜间于北斗下香水献
至早晨,用新倒流水
送下。
断魔如圣丹 治疟疾,不问久新。
信砒(一钱) 蜘蛛(大者三个) 雄黑豆(四十九粒)
上为末,滴水和丸,如豌豆大,如来日发,于今晚夜北斗下献于早晨,已纸裹,于耳内扎一丸。
立见愈,神圣!一粒可医三人。
辰砂丸 治一切脾胃虚,疟邪热毒者。
信砒 甘草(各一钱) 朱砂(三钱) 大豆(四十九粒)
上为末,滴水和丸,匀分作四十丸服,发日早晨日欲出,煎桃心汤下。忌热物。
疟神丹 治诸般疟疾。
信砒(一两) 雄黄(一钱)
上以于五月重五日,用棕子尖拌匀,研三千下,日未出,不令鸡、犬、妇人见,丸如
桐子大,未发前一日面东冷水下一丸。
趁鬼丹 治一切疟疾。神效!
信砒(一钱) 大豆(七钱) 雄黄 轻粉 荷叶(各半钱) 甘草(一寸)
上为末,滴水为丸,如小豆大,重午日未出,不见鸡、犬、妇人修合,每服一丸,无根
水下,平日夜视北斗,来日服。忌热物。
The *Suwen* states: All malaria arises from wind pathogens. Why do they have specific times for accumulation and cessation? It is due to the mutual contention of Yin and Yang above and below, and the shifting between deficiency and excess.
When Yang merges into Yin, Yin becomes full and Yang becomes deficient, resulting in chills and trembling of the jaw (Guhan). This occurs because summer heat injury causes heat qi to hide within the skin but outside the stomach and intestines. When the couli (pores) are open, autumn qi arrives; sweat is produced and wind is encountered. The pathogen combines with the Wei Qi (Defensive Qi). Wei Qi travels through the Yang meridians during the day and the Yin meridians at night. When the pathogen follows Wei Qi outward to the Yang level or inward to the Yin level, the external and internal levels contend with each other, causing daily attacks.
In cases where attacks occur every other day, the pathogen is deep, pressing inward on the Yin level. Yang Qi alone flares outward, while Yin pathogens remain fixed internally. Yin and Yang contend but cannot exit, hence the every-other-day attacks.
Regarding late or early onset: The pathogen lodges in the Fengfu point (GV16), moving down along the Du Meridian. Wei Qi convenes at Fengfu once a day and night, moving down one vertebral segment each day. The pathogen first lodges in the back. Whenever it reaches Fengfu, the couli open. When the couli open, the pathogen enters deeply, causing the disease to manifest later.
Cold belongs to Yin Qi, and heat belongs to Yang Qi. If cold is injured first and then wind, there is initial cold followed by heat, named Cold Malaria (Han Nue). If wind is injured first and then cold, there is initial heat followed by cold, named Warm Malaria (Wen Nue). If there is only heat without cold, it is because Yin Qi has exhausted first, leaving Yang Qi in sole dominance. Symptoms include shortness of breath, vexation, heat in the hands and feet, and nausea, named Bi Malaria.
Excess conditions require purging; deficiency conditions require tonifying. Heat is excess; cold is deficiency. Cold cannot be warmed even by fire; heat cannot be cooled even by ice. When Yin overcomes and merges into Yang, or Yang overcomes and merges into Yin, Yin excess manifests as cold, and Yang excess manifests as heat. Thus, malaria is caused by the irregular actions of Yin-Yang, Wind-Cold, and Deficiency-Excess pathogens.
Pixie Dan (Expel Evil Pill): Treats Lan-zhang ghost malaria, food-induced malaria, and frequent monthly attacks.
Mung Bean, Black Soybean (49 grains each), Realgar Arsenic (Xin Pi, 0.5 qian, ground separately), Red Lead (Huang Dan, 1 qian, used as coating), Cinnabar (Zhu Sha, 2 qian).
Grind all into powder, mix in a mortar, add drops of water to form pills, divide into 30 pills. Take one pill per dose. First, take seven heartwood pieces from a peach tree growing in the southeast direction, grind them to extract juice. Swallow the pill facing the sun in the early morning before sunrise, or use vinegar water. Take on the day of the attack.
Zhanxie Dan (Sever Evil Pill): Treats various types of malaria that do not cease.
Mung Bean, Adzuki Bean (30 grains each, peeled and returned to mixture), Cinnabar, Realgar Arsenic (1 qian each).
Grind into fine powder, mix thoroughly, add water to form pills, divide evenly into 10 pills. Take one pill in the morning. At night, offer incense to the Big Dipper until morning, then swallow with fresh running water.
Duanmo Rusheng Dan (Demon-Breaking Holy Pill): Treats malaria, regardless of duration.
Realgar Arsenic (1 qian), Large Spiders (3), Black Soybean (49 grains).
Grind into powder, add water to form pills the size of pea seeds. If an attack is expected tomorrow, perform offerings to the Big Dipper tonight until morning. Wrap one pill in paper and insert it into the ear. Cure will be seen immediately; this is divine! One pill can treat three people.
Chensha Wan (Cinnabar Pill): Treats all cases of Spleen-Stomach deficiency with malaria pathogen heat toxicity.
Realgar Arsenic, Licorice Root (Gan Cao, 1 qian each), Cinnabar (3 qian), Soybean (49 grains).
Grind into powder, add water to form pills, divide evenly into 40 pills. On the morning of the attack, when the sun is about to rise, swallow with decoction of peach heartwood. Avoid hot foods.
Mashen Dan (Malaria God Pill): Treats all types of malaria.
Realgar Arsenic (1 liang), Realgar (Xiong Huang, 1 qian).
On the fifth day of the fifth lunar month, mix with the tip of a zongzi leaf, grind 3,000 times. Prepare before sunrise; ensure no chickens, dogs, or women see the process. Form pills the size of paulownia seeds. The day before the attack, face east and swallow one pill with cold water.
Chengui Dan (Chase Ghost Pill): Treats all types of malaria. Extremely effective!
Realgar Arsenic (1 qian), Soybean (7 qian), Realgar, Calomel (Qing Fen), Lotus Leaf (He Ye, 0.5 qian each), Licorice Root (1 cun length).
Grind into powder, add water to form pills the size of adzuki beans. Prepare on the fifth day of the fifth lunar month before sunrise; ensure no chickens, dogs, or women witness the preparation. Take one pill per dose with unrooted water (rain/dew). Observe the Big Dipper at night daily, and take the next dose the following day. Avoid hot foods.