夫以脏腑禀赋不同，亦有将理失宜，遂致偏冷偏热，故方论中，有痼冷积热之说，痼冷
者，中寒也。多因真气既微，胃气不实，复啖生冷冰雪之属，致肠胃虚寒，阴既停凝，阳
不能正，大便洞泄，小便频并，鼻多清涕，呕吐涎沫，水谷不化，洒洒淅淅，皆阳虚阴盛之
所为也。积热者，脏腑燥也。多因精血既衰，三焦烦壅，复饵丹石酒炙之属，致肠胃蕴毒
，阳既炽盛，阴不能制，大便秘涩，小便赤淋，口苦咽干，涎稠眵泪，饮食无度，
，皆阴虚阳盛之所为也。治各有方。
固真气，暖丹田，坚筋骨，壮阳道，除久寒痼冷，补劳伤虚损。治男子腰肾久
冷，心腹积聚，胁下冷癖，腹中诸虫，失精遗溺，形羸力弱，脚膝疼痛，冷风顽痹，上气
衄血，咳逆寒热，霍乱转筋，虚滑下利。又治痔 湿 生疮，下血不止；及妇人血结
寒热，阴蚀疽等。
硫黄（十斤，先飞炼，去砂石秤，研为末，用瓷合盛，以水和赤石脂封口，盐泥固济，晒
干，地内先埋一小罐子，盛水令满，安合子在上，用泥固济讫，慢火养七日七夜，候足加顿
火一 。候冷取出)
上研为细末，每一两用炊饼一两，汤浸握去水脉为丸，如梧子大。每服三十丸，多至百
丸，温米饮下，空心服之。又治伤寒阴证，身冷脉微，手足厥逆，或吐或利，自汗不止，或
小便不禁，不拘丸数。并服，得身热脉出为度。
由于脏腑的先天禀赋存在差异，加之调理不当，容易导致身体出现偏寒或偏热的状况。因此，在方剂论述中，有“痼冷”和“积热”的说法。“痼冷”，就是中寒证。多因人体真气已经微弱，胃气不充实，又食用生冷冰雪之类的食物，导致肠胃虚寒。阴气停滞凝结，阳气不能正常运化，出现大便洞泄（如水样腹泻）、小便频数、鼻流清涕、呕吐涎沫、水谷不消化、身体战栗怕冷等症状，这些都是阳虚阴盛所致。“积热”，就是脏腑燥热。多因精血已经衰退，三焦烦闷壅滞，又服用丹石及酒炙烧烤之类的食物，导致肠胃蕴藏毒热。阳气炽盛，阴气不能制约，出现大便秘结涩滞、小便赤红淋痛、口苦咽干、唾液稠厚眼屎多、饮食无节制等症状，这些都是阴虚阳盛所致。针对这两种情况，各有相应的治疗方剂。
（金液丹的功效：）固护真气，温暖丹田，坚固筋骨，壮强阳道，祛除久治不愈的寒冷痼疾，补益劳伤虚损。治疗男子腰部肾脏长期寒冷，心腹部的积聚痞块，胁下的冷性癖块，腹中的各种寄生虫，遗精滑精，小便失禁，形体消瘦体力衰弱，脚膝疼痛，风寒引起的顽固性痹症，气逆上冲，鼻出血，咳嗽气逆伴寒热往来，霍乱转筋，虚寒性的滑脱腹泻。又治疗痔疮湿疮生疮，便血不止；以及妇人因寒热导致的血结，阴部蚀烂疽疮等病症。
硫黄（十斤，先经过飞炼处理，去除砂石后称重，研磨成粉末，用瓷盒盛装。用水调和赤石脂封口，用盐泥加固密封，晒干。在地里预先埋入一个小罐子，装满水，将装有硫黄的盒子放在小罐子上面，用泥封固密封后，用慢火煨养七天七夜。时间到了之后，稍微增加火力加热一下。待冷却后取出。）
将上述药物研磨成细末，每两药粉配一两炊饼（发酵面食），用热水浸泡后挤去水分，制成丸药，大小如梧桐子。每次服用三十丸，最多至一百丸，用温米汤送服，空腹服用。又治疗伤寒阴证，身体冰冷，脉搏微弱，手足厥冷，或者呕吐或者腹泻，自汗不止，或者小便失禁，不拘泥于丸药的数量，一并服用，以身体回暖、脉搏显现为度。
Due to differences in the innate constitution of the Zang-Fu organs, and improper regulation, the body may tend towards either cold or heat. Therefore, in discussions on prescriptions, there is the concept of "Stubborn Cold" (Gu Leng) and "Accumulated Heat" (Ji Re). "Stubborn Cold" refers to Cold Strike (Zhong Han). It often occurs when the True Qi (Zhen Qi) is already weak and the Stomach Qi (Wei Qi) is not solid, compounded by consuming raw, cold, or icy foods. This leads to deficiency-cold in the intestines and stomach. Yin stagnates and coagulates, while Yang cannot function normally, resulting in watery diarrhea, frequent urination, clear nasal discharge, vomiting of saliva and froth, undigested food in stool, and shivering chills. These are all manifestations of Yang deficiency and Yin excess. "Accumulated Heat" refers to dryness-heat in the Zang-Fu organs. It often arises from depletion of Essence and Blood, with vexation and obstruction in the San Jiao (Triple Burner), compounded by taking mineral elixirs (Dan Shi) or wine-fried/roasted foods. This causes toxic heat accumulation in the intestines and stomach. Yang becomes blazingly excessive, unable to be controlled by Yin, leading to constipation with difficulty, dark and painful urination, bitter taste in the mouth, dry throat, thick saliva, excessive eye discharge, and uncontrolled eating habits. These are all manifestations of Yin deficiency and Yang excess. Each condition has its specific treatment formula.
(Efficacy of Jin Ye Dan): Consolidates True Qi, warms the Dantian, strengthens bones and sinews, boosts Yang energy, eliminates chronic stubborn cold, and tonifies劳伤 (labor injury) and deficiency. It treats chronic coldness of the kidneys and lower back in men, accumulations and masses in the heart and abdomen, cold masses under the hypochondrium, various intestinal parasites, spermatorrhea and enuresis, emaciation and weakness, pain in the feet and knees, stubborn bi-syndrome caused by cold wind, rebellious Qi, epistaxis, cough with asthma alternating with aversion to cold and fever, cholera with muscle cramps, and deficiency-type loose stools. It also treats hemorrhoids, wet sores, continuous bleeding from the anus; as well as blood stasis with alternating cold and fever in women, and erosive ulcers of the vagina.
Sulfur (Shi Huang) (Ten jin [approx. 5kg], first refined and smelted, sand and gravel removed, weighed, ground into powder, stored in a porcelain jar. Seal the lid with a paste made of water and Chishizhi [Red Stone Lip]. Reinforce the seal with salt mud, dry it. Bury a small pot filled with water in the ground. Place the sealed sulfur jar on top of the buried pot. Seal tightly with mud. Roast slowly over low fire for seven days and nights. After the time is up, slightly increase the heat. Remove after cooling.)
Grind the above into a fine powder. For every liang [approx. 30g] of powder, use one liang of cooked dough (Chui Bing). Soak the dough in hot water, squeeze out excess moisture, and mix with the powder to form pills the size of a Chinese quince seed (Wu Zi Da). Take thirty pills per dose, up to one hundred pills, swallowed with warm rice broth, taken on an empty stomach. It also treats Yin syndrome of Shang Han (Cold Damage), characterized by cold body, faint pulse, cold limbs, vomiting or diarrhea, incessant spontaneous sweating, or urinary incontinence. The number of pills is not restricted; take them together until the body becomes warm and the pulse becomes palpable.