阴阳俱病终难起。两感伤寒慢料理。一日太阳与少阳。头痛口干烦饮水。二日阳明合太
阴。腹满身热如焚毁。不欲饮食鼻中干。 言妄语终难睡。三日少阳合厥阴。耳袭囊缩不知
人。厥逆水浆不入口。六日为期是死辰。
两感者。双经同病也。其症一日太阳与少阴俱病。二日阳明与太阴俱病。三日少阳与厥
阴俱病。此阴阳表里俱病。欲汗之则有里症。欲下之则有表症。经曰。其两感于寒者必死。
故仲景亦有治法。然仲景又曰。两感俱作。治有先后。如表症急者。当先救表。里症急者。
当先救里。故易老为制大羌活汤。意谓传经者。皆为阳邪。一于升阳。散热滋养阴藏。则感
之浅者。尚或可平也。
大羌活汤即九味。己独知连白术暨。散热培阴和表里。伤寒两感差堪慰。
百合一宗皆病形。无复经络最难明。欲卧又却不得卧。欲行还复不能行。饮食有美
美。虽如强健步难胜。如有寒热复如无。口舌小便还赤涩。药才入口即吐利。如有神灵来作
孽。病后虚劳多变成。百合地黄汤可啜。
百合者。百脉一宗也。其症行住坐卧不安。如有鬼神状。此是伤寒病后。虚邪所致
。宜以百合知母汤、百合鸡子汤、百合代赭汤、百合地黄汤主之。
伤寒懊恼胜怔忡。或实或虚皆胃中。结胸下早阳邪陷。阳明误下胃虚空。客气动膈
心中燥。栀子汤兼大陷胸。胃中燥屎宜承气。腹满头坚不可攻。
懊 者。谓郁闷不舒也。凡伤寒懊恼。有因短气烦躁。胸中懊恼。心下因硬则为结胸者
大陷胸汤主之。有因舌上白苔。虚烦不得眠。心下懊恼者。此邪热郁于胸中也。宜栀子豉汤
吐之。有因阳明无汗。小便不利。心中懊恼者。必发黄。宜茵陈蒿汤主之。有因阳明病下
后。懊恼而烦。胃中有燥屎者。此邪热结于胃中也。宜承气汤攻之。
阴阳两经同时受病，终究难以治愈。遇到两感伤寒症，处理时要缓慢谨慎。第一天太阳经与少阳经同病，出现头痛、口干、心烦想喝水的症状。第二天阳明经与太阴经同病，腹部胀满、身体发热如火烧毁，不想吃东西、鼻子干燥，胡言乱语且整夜难眠。第三天少阳经与厥阴经同病，耳朵听不见（或耳部不适）、阴囊收缩、神志不清不知人事，四肢厥冷、水浆不能入口，病程到第六天是死亡的时辰。
所谓“两感”，是指两条经脉同时患病。其症状表现为：第一天太阳经与少阴经同时发病；第二天阳明经与太阴经同时发病；第三天少阳经与厥阴经同时发病。这是阴阳表里同时受病。想要发汗解表，则因为有里证而不可行；想要攻下治里，则因为有表证而不可行。医经上说：“两感于寒者必死。”所以张仲景也有相应的治法。然而张仲景又说：“两感俱作，治有先后。”如果表证紧急，应当先救表；如果里证紧急，应当先救里。因此李东垣（易老）制定了大羌活汤。他的意思是，传经之邪多为阳邪，治疗应专注于升发阳气、散热并滋养阴脏，这样感受较浅的患者，或许还可以平复。
大羌活汤的组成包括九味药：苍术、黄芩、黄连、白术、知母、羌活、独活、防风、甘草。（注：原文“己”通“己”，指苍术；“独”指独活；“连”指黄连；“白术暨”指白术等）。此方能散热、培补阴液、调和表里，使两感伤寒患者稍得安慰。
百合病的整体表现都是身形异常，没有固定的经络归属，最难辨认。想躺卧却躺卧不安，想行走却又走不动。饮食方面，有时觉得美味，虽然看起来像健康人一样能走路但实际步履艰难。症状忽如寒热交作，又好像没有寒热。口舌和小便发红涩痛。药物刚入口就呕吐腹泻，病人感觉如有神灵作祟。这种病在伤寒病后容易转化为虚劳。可以用百合地黄汤服用。
所谓“百合”，是指全身百脉合为一宗。其症状表现为坐立行走卧都不安宁，状如有鬼神附体。这是伤寒病后，虚邪所致。适宜用百合知母汤、百合鸡子汤、百合代赭汤、百合地黄汤来主治。
伤寒中的懊恼症状比怔忡更严重。无论是实证还是虚证，都源于胃中。结胸症是因为过早攻下导致阳邪内陷；阳明病误用攻下导致胃气虚空。客气扰动膈膜，心中燥热，可用栀子汤兼大陷胸汤治疗。胃中有燥屎者宜用承气汤。若腹部胀满、头部坚硬，则不可攻下。
所谓“懊恼”，是指郁闷不舒的感觉。凡是伤寒引起的懊恼，有的因为短气烦躁，胸中懊恼，心下硬结则为结胸症，由大陷胸汤主治。有的因为舌上白苔，虚烦不得眠，心下懊恼，这是邪热郁结在胸中，适宜用栀子豉汤催吐。有的因为阳明病无汗、小便不利，心中懊恼，必然发黄，适宜用茵陈蒿汤主治。有的因为阳明病攻下后，懊恼而烦，胃中有燥屎，这是邪热结聚在胃中，适宜用承气汤攻下。
Yin and Yang meridians are both diseased, making recovery difficult. In cases of Lianggan Shanghan (Two-Meridian Cold Damage), treatment must be handled with caution. On the first day, Taiyang (Greater Yang) and Shaoyang (Lesser Yang) meridians are affected simultaneously, presenting with headache, dry mouth, irritability, and thirst. On the second day, Yangming (Yang Brightness) and Taiyin (Greater Yin) meridians are affected simultaneously, presenting with abdominal fullness, high fever as if burning, anorexia, dry nose, delirious speech, and insomnia. On the third day, Shaoyang and Jueyin (Terminal Yin) meridians are affected simultaneously, presenting with deafness or ear discomfort, retraction of the testicles, unconsciousness, cold extremities, and inability to swallow fluids. The sixth day marks the time of death.
"Lianggan" refers to the simultaneous disease of two meridians. The symptoms manifest as: on the first day, Taiyang and Shaoyin (Lesser Yin) meridians are diseased together; on the second day, Yangming and Taiyin meridians are diseased together; on the third day, Shaoyang and Jueyin meridians are diseased together. This constitutes a simultaneous disease of Yin/Yang and Exterior/Interior. If one attempts diaphoresis (sweating method), it is contraindicated due to Interior signs; if one attempts purgation, it is contraindicated due to Exterior signs. The Classics state: "Those who contract cold in two meridians will die." Therefore, Zhang Zhongjing also provided treatment methods. However, Zhang Zhongjing further stated: "When Lianggan occurs, treatment has a sequence." If Exterior signs are urgent, save the Exterior first; if Interior signs are urgent, save the Interior first. Thus, Li Dongyuan (Yi Lao) formulated Da Qianghuo Tang (Great Notopterygium Decoction). His intent was that transmitted pathogenic factors are mostly Yang pathogens; treatment should focus on raising Yang, clearing heat, and nourishing Yin organs. In such cases, patients with shallower infection might still recover.
Da Qianghuo Tang consists of nine ingredients: Cangzhu (Atractylodis Rhizoma), Huangqin (Scutellariae Radix), Lianqiao (Forsythiae Fructus - *Note: Text says 'Lian', usually Chaihu or Lianqiao, but context implies clearing heat, likely Huanglian or similar*, here interpreted as Huanglian Coptidis Rhizoma based on common formula composition), Baizhu (Atractylodis Macrocephalae Rhizoma), Zhimu (Anemarrhenae Rhizoma), Qianghuo (Notopterygii Rhizoma et Radix), Duhuo (Angelicae Pubescentis Radix), Fangfeng (Saposhnikoviae Radix), and Gancao (Glycyrrhizae Radix). This decoction clears heat, nourishes Yin, and harmonizes the Exterior and Interior, providing some relief for Lianggan Shanghan.
Baihe Bing (Lily Disease) presents with abnormal bodily forms, lacking specific meridian involvement, making it difficult to diagnose. Patients desire to lie down but cannot rest, desire to walk but cannot move. Regarding diet, food may taste good, and although they appear strong enough to walk, their steps are labored. Symptoms fluctuate like alternating chills and fever, yet sometimes seem absent. The mouth, tongue, and urine are red and astringent. Medication causes immediate vomiting or diarrhea upon ingestion, as if possessed by spirits. After Shanghan, this condition often transforms into Xu Lao (Deficiency Consumption). Baihe Dihuang Tang (Lily and Rehmannia Decoction) can be administered.
"Baihe" refers to the unity of all vessels. The symptoms include restlessness in walking, standing, sitting, and lying, resembling possession by ghosts or spirits. This is caused by deficient pathogens after Shanghan. It should be treated with Baihe Zhi Mu Tang (Lily and Anemarrhena Decoction), Baihe Jizi Tang (Lily and Egg Yolk Decoction), Baihe Daizhe Tang (Lily and Hematitum Decoction), or Baihe Dihuang Tang.
Shanghan Aonao (Regretful Distress) is more severe than Zhengchong (Palpitations). Whether excess or deficiency, it originates in the Stomach. Jie Xiong (Chest Binding) results from premature purgation causing Yang pathogens to sink. Misguided purgation in Yangming disease empties the Stomach Qi. Pathogenic qi disturbs the Diaphragm, causing central dryness; Zhi Zi Tang (Gardenia Decoction) combined with Da Xian Xiong Tang (Major Eavesdrop Chest Decoction) is used. Dry feces in the Stomach require Cheng Qi Tang (Order the Qi Decoction). If the abdomen is full and the head hard, purgation is forbidden.
"Aonao" refers to a feeling of depression and discomfort. In Shanghan, Aonao may arise from shortness of breath and irritability, with distress in the chest. If the epigastrium becomes hard, it is Jie Xiong, treated with Da Xian Xiong Tang. If there is a white coating on the tongue, empty irritability, insomnia, and epigastric distress, this is pathogenic heat stagnating in the chest; Zhi Zi Chi Tang (Gardenia and Fermented Soybean Decoction) should be used to induce vomiting. If there is no sweat and dysuria in Yangming disease, accompanied by central Aonao, jaundice will develop; Yinchen Hao Tang (Artemisia Capillaris Seed Decoction) is indicated. If Aonao and irritability occur after purgation in Yangming disease, with dry feces in the Stomach, this is pathogenic heat knotting in the Stomach; Cheng Qi Tang should be used to purge.