闻人氏云∶痘疮大便不通，小便如血，或结痈毒，身痘破裂，乃内火炽盛，失于解利，急用犀角地黄汤、小柴胡汤
加生地黄，四顺饮之类治之。窃谓前症若心脾热盛，用犀角地黄汤。心肝热盛，用小柴胡汤加生地黄。若大便不通，先
用四顺饮，次用犀角汤。若色赤 痛，二便不通，急用活命
饮加硝、黄。若色赤 痛，恶寒发热，用活命饮加麻黄。若因乳母怒火，用加味逍遥散、加味归脾汤。
一小儿痘根赤色，寒热作痛，此肝经有热也，先用加味小柴胡汤二剂，诸症渐退；又用加味逍遥散，三剂而贯脓，
末用八珍汤而愈。
一男子痘根赤痛，发热作渴，服紫草饮，痘裂出血，余谓心肝二经风火相搏，先用小柴胡汤加生地黄、犀角二剂，
用圣济犀角地黄汤而愈。
一小儿患前症，大便不利，小便赤涩，作渴饮冷，先君谓肠胃实热，先用凉膈散，一剂渐愈；又用犀角地黄汤、芹
菜汁而痊。
一小儿患此，诊乳母有郁火，用加味逍遥散、加味归脾汤而痊。同时患是痘而用杂药者，俱致不救。
凉膈散 治上焦实热，烦渴面赤，咽燥喉痛，便溺赤涩，狂言谵语，睡卧不安。
大黄 朴硝 甘草 连翘 山栀 黄芩 薄荷叶（各等分）
上为细末，每服少许，煎竹叶蜜汤调，乳母同服。
加味清胃饮（方见痘痈）
加味逍遥散（方见痘潮热）
犀角地黄汤（方见顶陷心烦）
加味小柴胡汤（即小柴胡汤加山栀、地黄，方见痘身疼）
八珍汤（方见顶陷灰白）
圣济归脾汤（方见痘痈）
闻人氏说：痘疮患者大便不通，小便带血，或者结成痈毒，身上痘疹破裂，这是由于体内火气炽盛，未能及时通过泻下或清解的方法治疗，应当紧急使用犀角地黄汤、小柴胡汤加生地黄，以及四顺饮等方剂进行治疗。我认为上述症状如果是因为心脾热盛，应使用犀角地黄汤；如果是心肝热盛，应使用小柴胡汤加生地黄；如果大便不通，先使用四顺饮，随后使用犀角汤；如果痘色红赤且疼痛，大小便都不通，应紧急使用活命饮加入芒硝、大黄；如果痘色红赤且疼痛，伴有恶寒发热，应使用活命饮加入麻黄；如果是由于乳母愤怒导致火气，应使用加味逍遥散、加味归脾汤。
有一个小孩痘根呈红色，寒热交替并疼痛，这是肝经有热，先用加味小柴胡汤两剂，各种症状逐渐消退；又用加味逍遥散，三剂后开始化脓；最后用八珍汤而痊愈。
有一个男子痘根红赤疼痛，发热口渴，服用紫草饮后，痘疹破裂出血，我认为这是心肝二经的风火相互搏结，先用小柴胡汤加生地黄、犀角两剂，再用圣济犀角地黄汤而痊愈。
有一个小孩患前述病症，大便不畅，小便红赤涩痛，口渴想喝冷水，我的父亲认为这是肠胃实热，先用凉膈散，一剂后逐渐好转；又用犀角地黄汤、芹菜汁而痊愈。
有一个小孩患此病，诊察发现其乳母有郁结之火，用加味逍遥散、加味归脾汤而痊愈。同时患有这种痘疹却使用杂乱药物的人，都导致无法救治。
凉膈散 治疗上焦实热，烦渴面赤，咽燥喉痛，大小便红赤涩痛，胡言乱语，睡眠不安。
大黄 朴硝 甘草 连翘 山栀 黄芩 薄荷叶（各等分）
以上药材研成细末，每次服用少许，用竹叶蜜汤煎调，乳母同服。
加味清胃饮（方剂见“痘痈”章节）
加味逍遥散（方剂见“痘潮热”章节）
犀角地黄汤（方剂见“顶陷心烦”章节）
加味小柴胡汤（即小柴胡汤加山栀、地黄，方剂见“痘身疼”章节）
八珍汤（方剂见“顶陷灰白”章节）
圣济归脾汤（方剂见“痘痈”章节）
Mr. Wenren stated: When a patient with smallpox (variolae) suffers from constipation, bloody urine, or the formation of carbuncles and toxic sores, along with the rupture of skin pustules, it is due to excessive internal fire that has failed to be resolved or purged in time. Urgent treatment should involve using Xijiao Dihuang Tang (Rhinoceros Horn and Rehmannia Decoction), Xiaochaihu Tang (Minor Bupleurum Decoction) added with Shengdihuang (Fresh Rehmannia Root), and similar formulas such as Sishun Yin. I opine that if the aforementioned symptoms are caused by excessive heat in the Heart and Spleen, Xijiao Dihuang Tang should be used; if caused by excessive heat in the Heart and Liver, Xiaochaihu Tang added with Shengdihuang should be used. If there is constipation, first use Sishun Yin, followed by Xijiao Tang. If the lesions are red and painful with obstruction of both bowel and bladder, urgently use Huoming Yin (Decoction for Saving Lives) added with Mangxiao (Mirabilite) and Dahuang (Rhubarb). If the lesions are red and painful accompanied by aversion to cold and fever, use Huoming Yin added with Mahuang (Ephedra). If the condition arises from the nursing mother's anger-induced fire, use Jiawei Xiaoyao San (Modified Free and Easy Wanderer Powder) and Jiawei Guipi Tang (Modified Restore the Spleen Decoction).
A child presented with red-based pustules, alternating chills and fever with pain, indicating heat in the Liver meridian. Initially, two doses of Jiawei Xiaochaihu Tang were administered, after which various symptoms gradually subsided. Subsequently, three doses of Jiawei Xiaoyao San were given, leading to suppuration. Finally, the child recovered after taking Bazhen Tang (Eight Treasures Decoction).
A man presented with red, painful pustule bases, fever, and thirst. After taking Zicao Yin (Arnebia Decoction), his pustules ruptured and bled. I attributed this to the struggle between wind and fire in the Heart and Liver meridians. He was first treated with two doses of Xiaochaihu Tang added with Shengdihuang and Xijiao (Rhinoceros Horn), and subsequently cured with Shengji Xijiao Dihuang Tang (Shengji Rhinoceros Horn and Rehmannia Decoction).
A child suffered from the aforementioned symptoms, presenting with difficult defecation, red and astringent urination, and thirst for cold drinks. My father diagnosed this as excess-heat in the Intestines and Stomach. He first prescribed Liangge San (Cooling the Chest Powder), after which the condition improved gradually with one dose. The child then recovered after taking Xijiao Dihuang Tang and Celery Juice.
Another child suffered from this condition. Upon examination, it was found that the nursing mother had stagnant fire. She was treated with Jiawei Xiaoyao San and Jiawei Guipi Tang, resulting in recovery. Those who contracted this type of smallpox simultaneously but used miscellaneous medications all died without hope of rescue.
Liangge San treats excess-heat in the Upper Jiao, characterized by irritability, thirst, flushed face, dry throat and sore throat, red and astringent urine and stool, delirious speech, and restless sleep.
Dahuang (Rhei Radix et Rhizoma), Puxiao (Natrii Sulfas), Gancao (Glycyrrhizae Radix et Rhizoma), Lianqiao (Forsythiae Fructus), Shanzhi (Gardeniae Fructus), Huangqin (Scutellariae Radix), Boheye (Menthae Haplocalycis Folium) (equal parts).
Grind the above into fine powder. Take a small amount each time, mixed with decoction of Bamboo Leaves and Honey. The nursing mother should take it concurrently.
Jiawei Qingwei Yin (Formula see "Carbuncle of Smallpox")
Jiawei Xiaoyao San (Formula see "Tidal Fever of Smallpox")
Xijiao Dihuang Tang (Formula see "Sunken Crown with Restless Heart")
Jiawei Xiaochaihu Tang (i.e., Xiaochaihu Tang added with Shanzhi and Dihuang, Formula see "Body Pain of Smallpox")
Bazhen Tang (Formula see "Sunken Crown with Ashy White Color")
Shengji Guipi Tang (Formula see "Carbuncle of Smallpox")