〔《灵》〕黄帝曰∶夫百病者，多以旦慧、昼安、夕加、夜甚，何也？岐伯曰∶朝则人气
始生，病气衰，故旦慧。日中人气长，长则胜邪，故安。夕则人气始衰，邪气始生，故加。
夜半人气入脏，邪独居于身，故甚也。黄帝曰∶其时有反者，何也？岐伯曰∶是不应四时之
气，脏独主其病者，是必以脏气之所不胜时者，甚；以其所胜时者，起也。（《一日分为四
时篇》）
〔《素》〕肝主春，足厥阴少阳主治，其日甲乙。病在肝，愈于夏。夏不愈，甚于秋。秋
不死，持于冬。起于春，禁当风。肝病者，愈在丙丁。丙丁不愈，加于庚辛。庚辛不死，持
于壬癸，起于甲乙。肝病者，平旦慧，下晡甚，夜半静。心主夏，手少阴太阳主治，其日丙
丁。病在心，愈在长夏。长夏不愈，甚于冬。冬不死，持于春。起于夏，禁温食热衣。心病
者，愈在戊己。戊己不愈，加于壬癸。壬癸不死，持于甲乙，起于丙丁。心病者，日中慧，
夜半甚，平旦静。脾主长夏，足太阴、阳明主治，其日戊己。病在脾，愈在秋。秋不愈，甚
于春。春不死，持于夏。起于长夏，禁温食、饱食、湿地、濡衣。脾病者，愈在庚辛。庚辛
不愈，加于甲乙。甲乙不死，持于丙丁，起于戊己。脾病者，日 慧，日出甚，下晡静
。肺主秋，手太阴、阳明主治，其日庚辛。病在肺，愈在冬。冬不愈，甚于夏。夏不死，持
于长夏，起于秋，禁寒饮食寒衣。肺病者，愈在壬癸。壬癸不愈，加于丙丁。丙丁不死，持
于戊己，起于庚辛。肺病者，下晡慧，日中甚，夜半静。肾主冬，足少阴、太阳主治，其日
壬癸。病在肾，愈在春。春不愈，甚于长夏。长夏不死，持于秋。起于冬，禁犯 HT
热食，温炙衣。肾病者，愈在甲乙。甲乙不愈，甚于戊己。戊己不死，持于庚辛，起于壬
癸。肾病者，夜半慧，四季甚，不晡静。夫邪气之客于身也，以胜相加，至其所生而愈，至
其所不胜而甚，至其所生而持，自得其位而起，必先定五脏之脉，乃可言间甚之时，死生之
期也。（《脏气法时论》）
上以五脏时日占病愈甚极准，钱仲阳深得此理，学人究心而又扩充之。
〔《灵》〕病在脏，沉而大者，其病易已，小为逆。病在腑，浮而大者，其病易已。脉口
滑小紧以沉者，病益甚，在中。人迎气大紧以浮者，其病益甚，在外。脉口滑以沉者，病日
进，在内。人迎脉滑盛以浮者，病日进，在外。脉口浮滑者，病日进。人迎沉而滑者，病日
损。（《五色篇》）
【《灵枢》】黄帝说：各种疾病，大多表现为早晨神志清爽、白天安宁、傍晚加重、夜间剧烈，这是为什么呢？岐伯说：早晨人气开始生发，病气衰退，所以早晨神志清爽。中午人气旺盛，旺盛就能战胜邪气，所以病情安宁。傍晚人气开始衰退，邪气开始亢盛，所以病情加重。半夜人气内入于脏，邪气独自居于体内，所以病情剧烈。黄帝说：如果有与上述规律相反的情况，是什么原因呢？岐伯说：这是因为不符合四时之气的影响，而是由脏腑自身主导病变，必定是在被该脏气所不胜的时辰病情加重；在被该脏气所胜的时辰病情好转。（出自《一日分为四时篇》）
【《素问》】肝主春季，足厥阴肝经和足少阳胆经主治，对应的日子是甲日和乙日。肝病在夏季痊愈。如果夏季不愈，则在秋季加重。如果秋季不死，则在冬季维持稳定。到春季会起色，治疗时应避免受风。肝病患者，痊愈的日子多在丙日和丁日。如果丙丁日不愈，则在庚日和辛日加重。如果庚辛日不死，则在壬日和癸日维持稳定，到甲乙日起色。肝病患者，早晨神志清爽，傍晚加重，半夜安静。心主夏季，手少阴心经和手太阳小肠经主治，对应的日子是丙日和丁日。心病在长夏（夏秋之交）痊愈。如果长夏不愈，则在冬季加重。如果冬季不死，则在春季维持稳定。到夏季会起色，治疗时应禁止吃温热的食物和穿厚热的衣服。心病患者，痊愈的日子多在戊日和己日。如果戊己日不愈，则在壬日和癸日加重。如果壬癸日不死，则在甲乙日维持稳定，到丙丁日起色。心病患者，中午神志清爽，半夜加重，早晨安静。脾主长夏，足太阴脾经和足阳明胃经主治，对应的日子是戊日和己日。脾病在秋季痊愈。如果秋季不愈，则在春季加重。如果春季不死，则在夏季维持稳定。到长夏会起色，治疗时应禁止吃温热食物、过饱、居住在潮湿之地或穿湿衣。脾病患者，痊愈的日子多在庚日和辛日。如果庚辛日不愈，则在甲日和乙日加重。如果甲乙日不死，则在丙丁日维持稳定，到戊己日起色。脾病患者，白天神志清爽，日出时加重，傍晚安静。肺主秋季，手太阴肺经和手阳明大肠经主治，对应的日子是庚日和辛日。肺病在冬季痊愈。如果冬季不愈，则在夏季加重。如果夏季不死，则在长夏维持稳定，到秋季会起色，治疗时应禁止吃寒冷饮食和穿寒冷衣物。肺病患者，痊愈的日子多在壬日和癸日。如果壬癸日不愈，则在丙日和丁日加重。如果丙丁日不死，则在戊己日维持稳定，到庚辛日起色。肺病患者，傍晚神志清爽，中午加重，半夜安静。肾主冬季，足少阴肾经和足太阳膀胱经主治，对应的日子是壬日和癸日。肾病在春季痊愈。如果春季不愈，则在长夏加重。如果长夏不死，则在秋季维持稳定，到冬季会起色，治疗时应禁止吃热食和用火烤热的衣服。肾病患者，痊愈的日子多在甲日和乙日。如果甲乙日不愈，则在戊日和己日加重。如果戊己日不死，则在庚辛日维持稳定，到壬癸日起色。肾病患者，半夜神志清爽，四季之末（辰、戌、丑、未月或日）加重，傍晚安静。大凡邪气侵犯人体，是按照五行相克的规律相加侵害的，到了相生之时则痊愈，到了被克之时则加重，到了相生之时则维持稳定，到了本气当令之时则起色。必须先确定五脏的脉象，才能谈论病情缓解与加重的时间以及生死期限。（出自《脏气法时论》）
以上关于根据五脏与时日关系来占断疾病痊愈与加重的理论非常准确，钱乙（钱仲阳）深得此理，后学者应深入研究并加以扩充发挥。
【《灵枢》】病位在脏，脉象沉而大的，其病容易治愈，脉小则为逆证。病位在腑，脉象浮而大的，其病容易治愈。寸口脉滑小紧以沉的，病情日益加重，病在内。人迎脉大紧以浮的，病情日益加重，病在外。寸口脉滑而以沉的，病情日益进展，病在内。人迎脉滑盛以浮的，病情日益进展，病在外。寸口脉浮滑的，病情日益进展。人迎脉沉而滑的，病情日益减轻。（出自《五色篇》）
[From *Ling Shu*] The Yellow Emperor said: Among various diseases, most manifest as lucidity in the morning, tranquility during the day, exacerbation in the evening, and severity at night. Why is this? Qibo replied: In the morning, the *Zhen Qi* (Upright Qi) begins to generate, and the pathogenic qi declines; therefore, there is lucidity in the morning. At noon, the *Zhen Qi* grows strong; when strong, it overcomes the evil; therefore, there is tranquility. In the evening, the *Zhen Qi* begins to decline, and the pathogenic qi begins to arise; therefore, there is exacerbation. At midnight, the *Zhen Qi* enters the Zang organs, leaving the pathogenic qi alone in the body; therefore, there is severity. The Yellow Emperor asked: What if there are cases contrary to this pattern? Qibo replied: This occurs when the condition does not follow the Qi of the Four Seasons, but is solely governed by the Zang organs. In such cases, the disease becomes severe during the time element that the Zang organ cannot overcome (Sheng); it improves during the time element that the Zang organ can overcome (Ke). (From "Chapter on Dividing One Day into Four Times")
[From *Su Wen*] The Liver governs Spring, with the Foot Jueyin (Liver) and Foot Shaoyang (Gallbladder) meridians taking charge, corresponding to the Jia and Yi days. When disease is in the Liver, it heals in Summer. If it does not heal in Summer, it exacerbates in Autumn. If it does not lead to death in Autumn, it stabilizes in Winter. It rises/recovers in Spring; wind exposure should be avoided. For Liver disease, recovery occurs on Bing and Ding days. If not recovered on Bing and Ding days, it exacerbates on Geng and Xin days. If it does not lead to death on Geng and Xin days, it stabilizes on Ren and Gui days, and rises/recovers on Jia and Yi days. Patients with Liver disease feel lucid at dawn, severe in the late afternoon, and quiet at midnight. The Heart governs Summer, with the Hand Shaoyin (Heart) and Hand Taiyang (Small Intestine) meridians taking charge, corresponding to the Bing and Ding days. When disease is in the Heart, it heals in Late Summer. If it does not heal in Late Summer, it exacerbates in Winter. If it does not lead to death in Winter, it stabilizes in Spring. It rises/recovers in Summer; warm food and hot clothing should be prohibited. For Heart disease, recovery occurs on Wu and Ji days. If not recovered on Wu and Ji days, it exacerbates on Ren and Gui days. If it does not lead to death on Ren and Gui days, it stabilizes on Jia and Yi days, and rises/recovers on Bing and Ding days. Patients with Heart disease feel lucid at noon, severe at midnight, and quiet at dawn. The Spleen governs Late Summer, with the Foot Taiyin (Spleen) and Foot Yangming (Stomach) meridians taking charge, corresponding to the Wu and Ji days. When disease is in the Spleen, it heals in Autumn. If it does not heal in Autumn, it exacerbates in Spring. If it does not lead to death in Spring, it stabilizes in Summer. It rises/recovers in Late Summer; warm food, overeating, damp places, and wet clothing should be prohibited. For Spleen disease, recovery occurs on Geng and Xin days. If not recovered on Geng and Xin days, it exacerbates on Jia and Yi days. If it does not lead to death on Jia and Yi days, it stabilizes on Bing and Ding days, and rises/recovers on Wu and Ji days. Patients with Spleen disease feel lucid during the day, severe at sunrise, and quiet in the late afternoon. The Lung governs Autumn, with the Hand Taiyin (Lung) and Hand Yangming (Large Intestine) meridians taking charge, corresponding to the Geng and Xin days. When disease is in the Lung, it heals in Winter. If it does not heal in Winter, it exacerbates in Summer. If it does not lead to death in Summer, it stabilizes in Late Summer, and rises/recovers in Autumn; cold food and cold clothing should be prohibited. For Lung disease, recovery occurs on Ren and Gui days. If not recovered on Ren and Gui days, it exacerbates on Bing and Ding days. If it does not lead to death on Bing and Ding days, it stabilizes on Wu and Ji days, and rises/recovers on Geng and Xin days. Patients with Lung disease feel lucid in the late afternoon, severe at noon, and quiet at midnight. The Kidney governs Winter, with the Foot Shaoyin (Kidney) and Foot Taiyang (Bladder) meridians taking charge, corresponding to the Ren and Gui days. When disease is in the Kidney, it heals in Spring. If it does not heal in Spring, it exacerbates in Late Summer. If it does not lead to death in Late Summer, it stabilizes in Autumn. It rises/recovers in Winter; hot food and clothes heated by moxibustion/fire should be avoided. For Kidney disease, recovery occurs on Jia and Yi days. If not recovered on Jia and Yi days, it exacerbates on Wu and Ji days. If it does not lead to death on Wu and Ji days, it stabilizes on Geng and Xin days, and rises/recovers on Ren and Gui days. Patients with Kidney disease feel lucid at midnight, severe at the end of each season (Chen, Xu, Chou, Wei), and quiet in the late afternoon. Generally, when pathogenic Qi invades the body, it acts according to the cycle of overcoming (Ke). It heals when reaching the generating (Sheng) phase, becomes severe when reaching the overcoming phase, stabilizes when reaching the generating phase again, and recovers when returning to its own position. One must first determine the pulse of the Five Zang organs to discuss the times of remission and exacerbation, as well as the periods of life and death. (From "Chapter on the Methods and Times of Zang Organs")
The above methods for predicting disease recovery and exacerbation based on the Five Zang organs and time/day are extremely accurate. Qian Zhongyang (Qian Yi) deeply understood this principle. Students of medicine should study it carefully and expand upon it.
[From *Ling Shu*] When the disease is in the Zang organs, a pulse that is deep and large indicates the disease will easily heal; a small pulse is adverse. When the disease is in the Fu organs, a pulse that is floating and large indicates the disease will easily heal. A Cun Kou (Radial artery) pulse that is slippery, small, tight, and deep indicates the disease is worsening, located internally. a Ren Ying (Carotid artery) pulse that is large, tight, and floating indicates the disease is worsening, located externally. A Cun Kou pulse that is slippery and deep indicates the disease is progressing daily, located internally. A Ren Ying pulse that is slippery, vigorous, and floating indicates the disease is progressing daily, located externally. A Cun Kou pulse that is floating and slippery indicates the disease is progressing daily. A Ren Ying pulse that is deep and slippery indicates the disease is diminishing daily. (From "Chapter on Five Colors")