虚邪之病母乘子。心火热乘脾土是。实邪之病子乘母。肺金燥乘脾土里。微邪之病妻乘
夫。
肾水寒乘脾土耳。贼邪之病夫乘妻。肝木气乘脾土矣。正邪之病为本病。脾土自甚湿如此。
所谓微实正虚邪。从微至甚求其理。细言各有甚与微。其余以此类推之。
辰戌之纪号太阳。泻水补火当在九。卯酉之纪号阳明。泻金补水六月取。寅申之纪号少
阳。
泻火补金在龙口。丑未之纪号太阴。泻土补水迎马首。子午之纪号少阴。泻火补金辰上候。
巳亥之纪号厥阴。泻木补土年在丑。只要先时取化源。此是玄珠斡天手。启玄注素别些个。
用药施针两俱可。却于四月始迎风乍前十二先发火。玄珠五穴分明说。数有生成多少别。木
泻太冲火太陵。土白金渊水溪穴。衰者还宜预补之。阴阳自有玄珠说。
上角或下角。治以辛凉且无驳。上下征或火。针而寒者自来可。上宫或下宫。若加之热古今
同。上宫中或角与征。上用苦热而已矣。下宫如遇征其中。下使甘温如喝起。下宫下若更逢
宫。下主苦温随表里。下宫或值中商羽。下非甘热将何据。上商与下商。苦小温又良。下商
中角征商羽。治下酸温是正方。上羽宜苦温。下羽宜苦热。上羽中逢宫羽商。上宜甘热一言
决。下羽中商角羽宫。下当甘热别无说。下属地。上属天。药食随宜慎勿偏。假若上宫宜苦
热。苦若用时须发泄。苦能燥热湿能通。甚者更加夺与越。苦热如将补湿家。纵无肉溃须皮裂。
虚邪致病，是母脏之邪侵犯子脏。例如心火之热邪侵犯脾土，便是这种情况。实邪致病，是子脏之邪侵犯母脏。例如肺金之燥邪侵犯脾土，病位在里。微邪致病，是妻（所胜）之邪侵犯夫（所不胜）。例如肾水之寒邪侵犯脾土，便是如此。贼邪致病，是夫（所不胜）之邪侵犯妻（所胜）。例如肝木之气侵犯脾土，便是这样。正邪致病，是本脏自盛之邪。例如脾土自身湿气过盛，便是如此。
所谓微、实、正、虚之邪，要从轻微到严重来探求其道理。详细来说，每种邪气都有偏盛和偏衰的区别，其余类推即可。
辰年和戌年的纪年称为太阳（风木司天或相关气化阶段），治疗应泻水补火，取穴在第九位（指井穴或特定序列，此处依原文直译）。卯年和酉年的纪年称为阳明（燥金司天或相关气化阶段），治疗应泻金补水，在六月（未月/长夏）选取。寅年和申年的纪年称为少阳（相火司天或相关气化阶段），治疗应泻火补金，取穴在龙口（指足厥阴肝经太冲穴等，依原文直译）。丑年和未年的纪年称为太阴（湿土司天或相关气化阶段），治疗应泻土补水，迎马首（指足太阴脾经或相关穴位，依原文直译）。子年和午年的纪年称为少阴（君火司天或相关气化阶段），治疗应泻火补金，在辰时观察或取穴。巳年和亥年的纪年称为厥阴（风木司天或相关气化阶段），治疗应泻木补土，取穴在丑位。只要预先从源头调理化生之机，这就是玄珠（王冰号玄珠子）运转天机的妙手。启玄子（王冰）注解《素问》时有别致的见解，用药施针两者皆可。然而从四月开始，风气乍起，前十二日先发火气。玄珠提出的五个穴位说得很清楚，但生成的数理各有不同。木气过盛泻太冲穴，火气过盛泻大陵穴，土气过盛泻白虎渊（即太白穴，古称或异名，此处保留原文意象或注为太白，WHO标准多用Taibai SP3，此处依原文“白渊”可能为传抄异文或特指，暂译为Baiyuan/Taibai），金气过盛泻经渠（溪穴可能指经渠或尺泽，依原文“溪穴”暂译Xixue/Jingqu），水气过盛泻复溜。正气衰弱者还宜预先补益。阴阳的道理自有玄珠子的论述。
上角（上焦风木）或下角（下焦风木），治疗用辛凉之法且不可驳杂。上征（上焦火热）或下征（下焦火热），针刺用寒法则自然可愈。上宫（上焦湿土）或下宫（下焦湿土），如果加上热象，古今治法相同。上宫中或逢角与征，上部治疗用苦热之法而已。下宫如果遇到征（火），中间治疗用甘温之法如喝起（指升提或温养）。下宫之下如果再逢宫（土），下部主治用苦温之法随表里而定。下宫或值中商（金）羽（水），下部不用甘热还有什么依据？上商（金）与下商（金），用小苦温之法又良善。下商中逢角、征、商、羽，治疗下部用酸温是正方。上羽（水）宜用苦温，下羽（水）宜用苦热。上羽中逢宫、羽、商，上部宜用甘热一言决断。下羽中逢商、角、羽、宫，下部应当用甘热别无他说。下属地，上属天。药食随适宜谨慎勿偏颇。假若上宫宜用苦热，苦味用时须发泄。苦能燥湿，热能通阳。甚者更加夺其有余与越其郁结。苦热如用于补益湿家之人，纵然没有肌肉溃烂，也必定皮肤皲裂。
The disease of deficient pathogenic factors (Xu Xie) involves the mother organ's pathogen invading the child organ. For instance, heart fire-heat invading spleen-earth is an example. The disease of excess pathogenic factors (Shi Xie) involves the child organ's pathogen invading the mother organ. For instance, lung metal-dryness invading spleen-earth, with the pathology located in the interior. The disease of slight pathogenic factors (Wei Xie) involves the "wife" (the organ I overcome) invading the "husband" (the organ that overcomes me). For instance, kidney water-cold invading spleen-earth is such a case. The disease of thief pathogenic factors (Ze Xie) involves the "husband" invading the "wife". For instance, liver wood-qi invading spleen-earth is so. The disease of correct pathogenic factors (Zheng Xie) is the self-excess of the primary disease. For instance, spleen-earth itself having excessive dampness is like this.
It is said that slight, excess, correct, and deficient pathogens should be understood by tracing from slight to severe to seek their principles. Specifically, each has its own excess and deficiency; the rest can be inferred by analogy.
Years of Chen and Xu are designated as Taiyang (Solar). To drain water and tonify fire, one should act at the ninth position [acupuncture point]. Years of Mao and You are designated as Yangming (Bright Yang). To drain metal and tonify water, one should select points in the sixth month. Years of Yin and Shen are designated as Shaoyang (Lesser Yang). To drain fire and tonify metal, one acts at the Dragon's Mouth [acupuncture point]. Years of Chou and Wei are designated as Taiyin (Greater Yin). To drain earth and tonify water, one welcomes the Horse's Head [acupuncture point]. Years of Zi and Wu are designated as Shaoyin (Lesser Yin). To drain fire and tonify metal, one observes or selects points at Chen hour. Years of Si and Hai are designated as Jueyin (Termination of Yin). To drain wood and tonify earth, one acts at the Ox position. As long as one extracts the source of transformation beforehand, this is the hand of Xuanzhu (Wang Bing's pseudonym) manipulating the heavens. Qixuanzi (Wang Bing) annotated the *Suwen* with distinct insights; both medication and acupuncture are viable. However, starting from the fourth month, when wind suddenly arises, the first twelve days emit fire qi. Xuanzhu clearly states five acupoints, but the numbers of generation and completion differ. For wood excess, drain Taichong (LR3); for fire excess, drain Daling (PC7); for earth excess, drain Baiyuan (likely referring to Taibai SP3); for metal excess, drain Xixue (likely Jingqu LU8 or similar); for water excess, drain Fuliu (KI7). Those with deficiency should also be pre-tonified. The principles of yin and yang are naturally explained by Xuanzhu.
Upper Jiao Wood (Shang Jiao) or Lower Jiao Wood (Xia Jiao): Treat with pungent-cool methods without impurity. Upper Jiao Fire (Shang Zheng) or Lower Jiao Fire (Xia Zheng): Acupuncture with cold methods will naturally resolve it. Upper Jiao Earth (Shang Gong) or Lower Jiao Earth (Xia Gong): If heat is added, ancient and modern treatments are the same. In Upper Jiao, if encountering Wood or Fire: Use bitter-hot methods for the upper part. In Lower Jiao, if encountering Fire: Use sweet-warm methods in the middle. In Lower Jiao, if additionally encountering Earth: Use bitter-warm methods for the lower part according to exterior-interior dynamics. In Lower Jiao, if encountering Metal or Water: What basis is there for not using sweet-hot? Upper Metal (Shang Shang) and Lower Metal (Xia Shang): Small bitter-warm methods are good. For Lower Metal encountering Wood, Fire, Metal, or Water: Treating the lower part with sour-warm is the correct formula. Upper Water (Shang Yu) should use bitter-warm; Lower Water (Xia Yu) should use bitter-hot. In Upper Water, if encountering Earth, Water, or Metal: The upper part should use sweet-hot, decided in one word. In Lower Water, if encountering Metal, Wood, Water, or Earth: The lower part should definitely use sweet-hot, leaving no other explanation. The lower belongs to Earth, the upper belongs to Heaven. Medication and food should be suitable and cautious, avoiding bias. If Upper Jiao Earth requires bitter-hot, when using bitter flavors, one must vent. Bitter can dry dampness, heat can unblock. For severe cases, further deplete the excess and vent the stagnation. Using bitter-hot to tonify those with dampness is dangerous; even without muscle ulceration, skin cracking will surely occur.