论曰诸黄胆酒疸女劳疸久不已，皆变为黑疸。其状小腹满。身体尽黄，额上反黑。足下
热。大便黑是也。黄本脾病。脾者土也，脾病不已。传其所胜。肾斯受之，肾为水脏。其经
足少阴，其色黑。病在肾故小腹满色黑。大便黑足下热，是皆足少阴经受病之证。
治诸疸久不瘥。变成黑疸。当归汤方
当归（三两） 桂（去粗皮六两） 麦门冬（去心一两半） 大黄（锉炒一两） 茵陈
蒿黄芩
（碎） 人参 甘草
上一十四味。锉如麻豆。每服三钱匕。水一盏。入大枣两枚劈破。煎取七分。去滓温服。
日三。一方无黄 。
治黄胆变成黑疸。医所不能疗。土瓜饮方
土瓜根
上一味。每日空心服半盏，其病随小便出即愈，然须量病患强壮者。可半盏。羸人一合。
如无生者，即锉干者一两，水一盏半。煎取七分，去滓顿服。羸人量减。
治黑疸，身体及大便并黑，及黄胆久不瘥。瓜蒂散方
瓜蒂（一分） 雄黄（醋煮研一钱） 甘草（炙锉一两） 女萎（二两）
上四味，捣罗为细散，每服一字匕。用赤小豆二十粒，茯苓一分。水一盏。煎至六分。
去滓调服。须臾当吐。吐止即愈。
治黑疸，身体黯黑。小便涩。茵陈蒿丸方
茵陈蒿 赤茯苓（去黑皮） 葶苈子（微炒各一两） 枳壳（去瓤麸炒） 白术（各一
两一分）
蜀椒（去闭口及目炒令出汗） 当归（切焙） 干姜（炮过各半两） 甘遂（炮一分）
上一十二味，捣罗为末，炼蜜和捣三五百杵。丸如绿豆大，每服空心米饮下一十丸，日
三。
论述说：各种黄疸、酒疸、女劳疸如果长期不愈，都会转变为黑疸。其症状表现为小腹部胀满，全身皮肤发黄，但额头反而发黑，脚底发热，大便颜色发黑。
黄疸本属于脾脏的疾病。脾在五行中属土，脾病如果不治愈，会传变给其所克制的脏腑（即肾）。肾脏因此受邪，肾为水脏，其经脉为足少阴经，其色为黑。因为病位在肾，所以出现小腹胀满、面色发黑、大便发黑、脚底发热等症状，这些都是足少阴经受病的证候。
治疗各种黄疸日久不愈，转变为黑疸的当归汤方：
当归（三两）、桂枝（去除粗皮六两）、麦门冬（去心一两半）、大黄（切碎炒制一两）、茵陈蒿、黄芩（捣碎）、人参、甘草。
以上十四味药，切碎如麻豆大小。每次服用三钱匕，加水一盏，放入两枚劈破的大枣，煎取七分药液，去渣后温服。每日三次。另一版本方中没有黄芩。
治疗黄疸转变为黑疸，医生难以治疗的土瓜饮方：
土瓜根。
以上一味药。每天空腹服用半盏，病情随小便排出即可痊愈，但必须根据患者体质强弱来决定剂量。强壮者可服半盏，虚弱者服一合。如果没有鲜品，可将干品切碎一两，加水一盏半，煎取七分药液，去渣后一次性服用。虚弱者酌情减量。
治疗黑疸，身体及大便均发黑，以及黄疸日久不愈的瓜蒂散方：
瓜蒂（一分）、雄黄（用醋煮后研细一钱）、甘草（炙烤后切碎一两）、女萎（二两）。
以上四味药，捣筛成细粉。每次服用一字匕。用赤小豆二十粒、茯苓一分，加水一盏，煎至六分。去渣后调服药粉。不久应当呕吐，吐止则病愈。
治疗黑疸，身体黯黑，小便涩滞的茵陈蒿丸方：
茵陈蒿、赤茯苓（去除黑皮）、葶苈子（微炒各一两）、枳壳（去除瓤麸炒）、白术（各一两一分）、蜀椒（去除闭口及目，炒令出汗）、当归（切片焙干）、干姜（炮制过各半两）、甘遂（炮制一分）。
以上十二味药，捣筛成末，用炼蜜调和并捣三五百下。制成如绿豆大小的丸剂。每次空腹用米饮送服十丸，每日三次。
Commentary states: Various types of jaundice, including wine jaundice (Jiu Dan) and labor-induced jaundice from sexual excess (Nü Lao Dan), if left untreated for a long time, will all transform into black jaundice (Hei Dan). The manifestations include fullness in the lower abdomen, yellowing of the entire body, yet the forehead appears dark/black, heat under the soles of the feet, and black stools.
Jaundice originates as a disease of the Spleen. The Spleen corresponds to Earth in the Five Phases. If Spleen disease persists, it transmits to the organ it overcomes, which is the Kidney. Thus, the Kidney becomes affected. The Kidney is the Water organ; its meridian is the Foot-Shaoyin (Lesser Yin of the Foot), and its associated color is Black. Since the pathology resides in the Kidney, symptoms such as lower abdominal fullness, dark complexion, black stools, and heat under the soles occur. These are all signs of disease affecting the Foot-Shaoyin meridian.
Dang Gui Tang (Angelica Decoction) for treating various jaundices that have persisted for a long time and transformed into black jaundice:
Dang Gui (Radix Angelicae Sinensis, 3 liang), Guizhi (Ramulus Cinnamomi, removed coarse bark, 6 liang), Maimendong (Radix Ophiopogonis, core removed, 1.5 liang), Dahuang (Radix et Rhizoma Rhei, crushed and stir-fried, 1 liang), Yinchenshao (Herba Artemisiae Scopariae), Huangqin (Radix Scutellariae, crushed), Ren Shen (Radix Ginseng), Gancao (Radix Glycyrrhizae).
The above fourteen ingredients are crushed like hemp seeds. For each dose, take three qianbi (approx. 9-10g), add one zhan (approx. 200ml) of water, insert two cracked large dates (Zao Ren), decoct until seven-tenths remains, remove dregs, and take warm. Three times daily. Another version excludes Huangqin.
Tugua Yin (Trichosanthes Root Drink) for treating jaundice transformed into black jaundice, refractory to medical treatment:
Tugua Gen (Radix Trichosanthis Kirilowii).
The above single ingredient. Take half a zhan on an empty stomach daily. The disease will resolve as it exits via urination. However, dosage must be adjusted according to the patient's constitution. Robust patients may take half a zhan; frail patients should take one he (approx. 20ml). If fresh root is unavailable, crush one liang of dried root, add one and a half zhan of water, decoct until seven-tenths remains, remove dregs, and take in one dose. Frail patients should reduce the dose accordingly.
Gua Di San (Melon Seed Powder) for treating black jaundice with darkening of the body and stools, and persistent jaundice:
Gua Di (Fructus Momordicae), Xionghuang (Realgar, boiled in vinegar and ground, 1 qian), Gancao (Radix Glycyrrhizae, roasted and crushed, 1 liang), Nüwei (Caulis Polygoni Multiflori, 2 liang).
The above four ingredients are pounded and sifted into a fine powder. Each dose takes one zi bi (approx. 1-2g). Use twenty grains of Chi Xiaodou (Seed Vigna Angularis) and one fen of Fuling (Poria) with one zhan of water, decoct until six-tenths remains. Remove dregs and mix with the powder. Vomiting should occur shortly after administration; once vomiting stops, the illness resolves.
Yin Chen Hao Wan (Artemisia Scoparia Pill) for treating black jaundice with darkened body and obstructed urine:
Yinchenhao (Herba Artemisiae Scopariae), Chi Fuling (Poria with red skin, outer black skin removed), Tinglizi (Semen Lepidii seu Descurainiae, lightly stir-fried, 1 liang each), Zhike (Fructus Aurantii, pith removed, bran-roasted), Baizhu (Rhizoma Atractylodis Macrocephalae, 1 liang 1 fen each), Shujiao (Pericarpium Zanthoxyli, remove closed-mouth and eyes, stir-fry until sweat appears), Danggui (Radix Angelicae Sinensis, sliced and baked), Ganjiang (Rhizoma Zingiberis, processed, 0.5 liang each), Gansui (Radix Euphorbiae Kansui, processed, 1 fen).
The above twelve ingredients are pounded into powder, mixed with refined honey, and pounded 300-500 times. Form pills the size of mung beans. Each dose takes ten pills on an empty stomach with rice water, three times daily.