治伤寒一二日便成阳毒，或服药吐下之后变成阳毒，身重腰背痛，烦闷不安，狂言，或
走或见鬼，或吐血下痢，其脉浮大数，面赤斑斑如锦文，咽喉痛，唾脓血，五日可治，至七
日不可治宜服方。
升麻 甘草（各半两） 当归 蜀椒 雄黄 桂心（各六铢）
上六味 咀，以水五升煮取二升半，分三服，如人行五里进一服，温覆手足，毒出则
汗，汗出则解，不解重作，服之得吐亦佳。（仲景无桂心有鳖甲手大一片，《肘后》与《千
金》同《古今录验》有栀子六铢、鳖甲如手一片。）
治伤寒初起一二日便结成阴毒，或服药六七日以上至十日变成阴毒，身重背强，腹中
绞痛，咽喉不利，毒瓦斯攻心，心下坚强，短气不得息，呕逆唇青面黑，四肢厥冷，其脉沉细
紧数，仲景云此阴毒之候，身如被打，五六日可治，至七日不可治也方。
甘草 升麻（各半两） 当归 蜀椒（各六铢） 鳖甲（一两）
上五味 咀，以水五升煮取二升半，分三服，如人行五里顷更进一服，温覆发汗，毒
当从汗出，汗出则愈。若不汗则不除，重作服。（仲景方无蜀椒。）
治伤寒肢节疼痛，纳寒外热虚烦方。
芍药 甘草（各二两） 干姜 黄芩（各三两） 桂心（四两） 大枣（十五枚）
上六味 咀，以水一斗煮取五升，去滓，温服一升，日三夜二，覆令小汗。
治疗伤寒发病一两天就转化为阳毒，或者在服用催吐、泻下药物后转化为阳毒，症状表现为身体沉重、腰背疼痛，心中烦闷不安，胡言乱语，有的四处走动或产生幻觉看见鬼怪，有的吐血或下痢，脉象浮大且数，面色红赤并出现如锦绣花纹般的斑纹，咽喉疼痛，咳唾脓血。发病五天内可以治疗，到了第七天则难以治愈，应当服用以下方剂。
以上六味药，切碎，用水五升煎煮至二升半，分三次服用。按照行人行走五里路的时间间隔进服一次，服药后覆盖衣被以温暖手足，毒邪随汗液排出则病愈；若汗出后病未解，可再次煎服。服药后若能呕吐也是好的。（张仲景的方剂中没有桂心，有一片手掌大小的鳖甲，《肘后备急方》与《千金方》相同，《古今录验》中有栀子六铢、一片手掌大小的鳖甲。）
治疗伤寒初起一两天就结聚为阴毒，或者服药六七天以上直到十天转化为阴毒，症状表现为身体沉重、背部僵硬，腹中绞痛，咽喉不利，毒气攻心，心下部坚硬，呼吸短促不能深呼吸，呕吐逆气，嘴唇发青、面色发黑，四肢厥冷，脉象沉细紧数。张仲景说这是阴毒的症状，身体感觉像被打过一样，五六天内可以治疗，到了第七天则难以治愈。以下为此证所用的方剂。
以上五味药，切碎，用水五升煎煮至二升半，分三次服用。按照行人行走五里路的时间间隔再进服一次，覆盖衣被以发汗，毒邪应当从汗液中排出，汗出则痊愈。如果不出汗则病邪不能去除，需重新煎服。（张仲景的方剂中没有蜀椒。）
治疗伤寒引起的肢体关节疼痛，外感寒邪而体内有热，虚烦不安的方剂。
芍药 甘草（各二两） 干姜 黄芩（各三两） 桂心（四两） 大枣（十五枚）
以上六味药，切碎，用水一斗煎煮至五升，滤去药渣，温服一升，白天服三次，夜间服两次，覆盖衣被使身体微微出汗。
To treat Yang Poison (Yang Du, a severe toxic condition characterized by heat and toxicity) that develops into Yang Poison within one or two days of contracting Cold Damage (Shanghan), or transforms into Yang Poison after taking emetic or purgative medicines. Symptoms include heavy body, pain in the waist and back, mental restlessness and discomfort, delirious speech, wandering about, or hallucinations of seeing ghosts; hematemesis (vomiting blood) or dysentery may occur. The pulse is floating, large, and rapid. The face is red with mottled spots resembling brocade patterns. There is sore throat and expectoration of pus and blood. It is treatable within five days, but becomes untreatable after seven days. The following prescription should be taken.
Shengma (Rhizoma Cimicifugae), Gancao (Radix Glycyrrhizae) (each 0.5 liang); Danggui (Radix Angelicae Sinensis), Shujiao (Fructus Zanthoxyli), Xionghuang (Realgar), Guixin (Cortex Cinnamomi) (each 6 zhu).
The above six herbs are coarsely crushed. Boil in 5 sheng of water until reduced to 2.5 sheng. Divide into three doses. Administer one dose every interval equivalent to walking five li. Cover the patient warmly to warm the hands and feet. When the toxin is expelled through sweating, the disease resolves. If not resolved after sweating, prepare another dose. Vomiting after administration is also considered beneficial. (Zhang Zhongjing's formula does not contain Guixin but includes one piece of Biejia [Carapax et Plastrum Testudinis] the size of a hand; *Zhouhou* and *Qianjin* are identical to this; *Gujin Luyan* contains Zhizi [Fructus Gardeniae] 6 zhu and one piece of Biejia the size of a hand.)
To treat Yin Poison (Yin Du, a severe toxic condition characterized by cold and toxicity) that forms within one or two days of the onset of Cold Damage, or transforms into Yin Poison after taking medicines for six to seven days up to ten days. Symptoms include heavy body, stiffness of the back, colicky abdominal pain, difficulty in the throat, toxin qi attacking the heart, hardness below the heart, shortness of breath with inability to take deep breaths, vomiting and regurgitation, cyanosis of the lips, blackening of the face, and cold limbs. The pulse is deep, fine, tight, and rapid. Zhang Zhongjing states this is the presentation of Yin Poison, where the body feels as if beaten. It is treatable within five to six days, but becomes untreatable after seven days. The following prescription is indicated.
Gancao (Radix Glycyrrhizae), Shengma (Rhizoma Cimicifugae) (each 0.5 liang); Danggui (Radix Angelicae Sinensis), Shujiao (Fructus Zanthoxyli) (each 6 zhu); Biejia (Carapax et Plastrum Testudinis) (1 liang).
The above five herbs are coarsely crushed. Boil in 5 sheng of water until reduced to 2.5 sheng. Divide into three doses. Administer another dose after an interval equivalent to walking five li. Cover the patient to induce sweating. The toxin should be expelled through sweat; recovery occurs when sweat appears. If no sweat occurs, the pathogen is not eliminated, so prepare another dose. (Zhang Zhongjing's formula does not contain Shujiao.)
To treat limb and joint pain caused by Cold Damage, external cold invasion with internal heat, and empty vexation (Xu Fan).
Shaoyao (Radix Paeoniae Alba), Gancao (Radix Glycyrrhizae) (each 2 liang); Jiangjiang (Rhizoma Zingiberis Recens), Huangqin (Radix Scutellariae) (each 3 liang); Guixin (Cortex Cinnamomi) (4 liang); Dazao (Fructus Jujubae) (15 pieces).
The above six herbs are coarsely crushed. Boil in 1 dou of water until reduced to 5 sheng. Strain the dregs. Take 1 sheng warm. Administer three times during the day and twice at night. Cover the patient to induce slight sweating.