素问黄帝曰∶夫热病者,皆伤寒之类也,或愈或死,其死皆以六七日间,其愈皆以十日
以上者何也。岐伯曰∶巨阳者,诸阳之属也,其脉连于风府,故为诸阳主气也,人之伤于寒
也则为病热,热虽甚不死,其两感于寒而病者必死。帝曰愿闻其状。岐伯曰∶一日巨阳受之,
故头项痛腰脊强。二日阳明受之,阳明主肌肉,其脉夹鼻络于目,故身热目疼而鼻干不得卧
。三日少阳受之少阳主胆,其脉循胁络于耳,故胸胁痛而耳聋三阳经络皆受其病,而未入于
脏者故可汗而已。四日太阴受之,太阴脉布胃中络于隘,故腹满而隘干。五日少阴受之,少
阴脉贯肾络肺系舌本,故口燥舌干而渴。六日厥阴受之,厥阴脉循阴器而终于肝,故烦满而
囊缩。三阴三阳五脏六腑皆受病,营卫不行,五脏不通,则死矣。其不两感于寒者,七日巨
阳病衰,头痛少愈。八日阳明病衰,身热少愈。九日少阳病衰,耳聋微闻。十日太阴病衰,
腹减如故,则思饮食。十一日少阴病衰,渴止不满,舌干已而嚏。十二日厥阴病衰,囊纵少
腹微下,大气皆去,病日已矣。
帝曰∶治之奈何。岐伯曰∶治之各通其脏。脉病日衰已矣,其未满三日者可汗而已,其
满三日可泄而已。
又帝曰∶其病两感于寒者其脉应与其病形何如。岐伯曰∶两感于寒病者,病一日则巨阳
与少阴俱病则头痛口干烦满而渴也。二日则阳明与太阴俱病,则腹满身热不欲食,谵语。三
日则少阳与厥服俱病,则耳聋囊缩厥逆,水浆不入,不知人则六日而死。
帝曰∶五脏已伤,六腑不通,营卫不行,如是之后,三日乃死,何也。岐伯曰∶阳明者
十二经脉之长也,其气血盛,故不知人,三日其气乃尽,故死。(出第九卷中甲乙太素同)
病源伤寒一日,太阳受病,太阳者,小肠之经也,为三阳之首,故先受病,其脉络于腰
脊,主于头项,故得病一日而头项背膊腰脊痛也。
又伤寒二日,阳明受病,阳明者,胃之经也,主于肌肉,其脉络鼻入目,故得病二日,
内热鼻干不得眠也,诸阳在表表始受病在皮肤之间,故可摩膏火灸发汗而愈。(出第七卷中)
仲景伤寒论伤寒一二日,心中悸而烦,小建中汤主之方。
桂心(三两) 甘草(炙二两) 生姜(三两) 大枣(十二枚擘) 胶饴(一升) 芍
药(六两)
上六味切,以水七升,先煮五味,取三升,去滓纳饴,更上火微煮,令消解,温服一升
,日三服,如呕家不可服建中汤,以甜故也。忌海藻菘菜生葱。(千金翼同出第三卷中)
(张仲景伤寒论伤寒一二日内麻黄汤主之此云小建中汤非也此方但治心中悸而烦)
病源伤寒三日,少阳受病,少阳者,胆之经也,其脉循于胁上于颈耳,故得病三日,胸
胁痛而耳聋也,三阳经络始相传病,未入于脏,故皆可汗而解。(出第七卷中)
仲景伤寒论,疗太阳病三日发其汗,病不解,蒸蒸发热者,属调胃承气汤方。
甘草(炙三两) 芒硝(半升) 大黄(四两)
上三味切,以水三升煮二物取一升去滓,纳芒硝更煮微沸,温温顿服,以调胃承气则愈
。忌海藻菘菜,经心录同。(出第十卷中,张仲景伤寒论三日亦可服麻黄汤此云调胃承气汤
非也此方但治三日发汗不解蒸蒸发热者)
病源∶伤寒四日,太阴受病,太阴者,脾之经也,为三阴之首,是知三日以前,阳受病
讫,传之于阴,而太阴受病焉,其脉络于脾,主于喉嗌,故得病四日腹满而嗌干,其病在胸
膈也,故可吐而愈。
又伤寒五日,少阴受病,少阴者,肾之经也,其脉贯肾络肺系于舌,故得病五日,口燥
舌干,渴而引饮也,其病在腹,故可下而愈矣。(并出第七卷中)
仲景伤寒论∶伤寒四五日,身热恶风,颈项强,胁下满,手足温而渴者,小柴胡汤主之
方。
柴胡(半斤) 栝蒌根(四两) 桂心(三两) 黄芩(三两) 牡蛎(三两) 甘草
(炙二两) 干姜(三两)
上七味切,以水一斗二升,煮取六升,去滓更煎取三升,温服一升,日三服,初服微烦
,温覆汗出者便愈也。忌生葱海藻菘菜。(范汪同出第三卷中,仲景伤寒论名柴胡姜桂也合
用柴胡人参甘草黄芩半夏生姜大枣七味小柴胡汤是也玉函千金翼同)
病源∶伤寒六日,厥阴受病,厥阴者肝之经也,其脉循阴器络于肝,故得病六日烦满而
囊缩也,此则阴阳俱受病,毒瓦斯在胸,故可下而愈。
又伤寒七日,太阳病衰,头痛少愈,伤寒七日病法当小愈,阴阳诸经传尽故也,今七日
以后,病反甚不除者,欲为再经病也,再经病者,是阴阳诸经络重受病故也。(并出第七卷
中)
仲景伤寒论∶疗伤寒不大便六七日,头痛有热,与承气汤,其人小便反清者,知不在里
,仍在表也,当须发汗,若头痛者必衄血,宜桂枝汤方。(士弱氏曰药非衄后用乃当汗时用
则不衄矣先未汗故衄耳)
桂枝汤方
桂枝 芍药(各三两) 甘草(炙二两) 生姜(三两) 大枣(十二枚擘)
上五味切,以水七升,煮取三升,去滓,温服一升,须臾吃稀粥一升助药力,覆取微汗
。忌生葱海藻菘菜。(集验备急文仲范汪同,仲景伤寒论此方六七日病在表者可服之)
又伤寒五六日,呕而发热者,柴胡汤证具,而以他药下之,柴胡证仍在,故可与柴胡汤
,此虽已下之不为逆,必蒸蒸而振却,发热汗出而解。
病源∶伤寒八日,阳明病衰,身热少愈,伤寒八日,病不解者,或者诸阴阳经络重受于
病,或因发汗吐下之后,毒瓦斯未尽,所以病证犹存也。
又伤寒九日,少阳病衰,耳聋微闻,伤寒九日以上病不除者,或初一经受病,即不能相
传,或已传三阳讫,而不能传于阴,致停滞累日,病证不罢者,或三阳三阴传病已毕,又重
感于寒,故日数多而病候改变。(出第七卷中)
仲景伤寒论∶疗伤寒八九日,风湿相搏,身体疼痛而烦,不能自转侧,不呕不渴,下之
脉浮虚而涩者,属桂枝附子汤。若大便硬,小便自利者,附子白术汤。
桂枝附子汤方
桂心(四两) 附子(三枚炮去皮) 生姜(三两) 甘草(二两炙) 大枣(十二枚
擘)
上五味切,以水六升,煮取二升,去滓,温分三服。忌生葱猪肉海藻菘菜。
附子白术汤方
白术(四两) 大枣(十二枚) 甘草(炙一两) 生姜(二两) 附子(三枚炮去皮
四破)
上五味切,以水六升,煮取二升,去滓,温分三服,初一服其人身如痹,半日许复服之
都尽,其人如冒状者勿怪,此以附子术并走皮中逐水气未除,故使人如冒状也,本云附子一
枚,今加之二枚,名附子汤,忌葱猪肉菘菜海藻桃李雀肉等。(千金翼同出第十一卷中,张
仲景论法当加桂枝四两此本一方二法以大便硬小便自利故去桂也以大便不硬小便不利当加桂
附
病源,伤寒十日,太阴病衰,腹减如故,则思饮食,十一日少阴病衰,渴止不满,舌干
已而嚏,十二日,厥阴病衰,囊纵,少腹微下,大气皆去,病日已矣。(出第七卷中素问太
素甲乙并同)
仲景伤寒论∶疗吐下之后,不大便,五六日至十余日,日晡所发潮热,不恶寒,独语如
见鬼状,若剧者发则不识人,循衣摸床,惕而不安,微喘,但发热谵(谵疾而寤寐自语也)
语
者,属大承气汤方。
大黄(去皮四两) 陈枳实(炙五枚) 芒硝(三合) 浓朴(半斤)
上四味切,以水一斗,先煮二物,取五升,去滓,纳大黄煮取二升去滓,纳芒硝煮一二
沸,分为两服,初一服便得利者止,后服不必尽剂。(千金方并翼同出第五卷中)
又太阳病过经十余日,及二三下之后,四五日柴胡证仍在者,先与小柴胡汤,呕不止,
心下急,(一云呕止小安)郁郁微烦者,为未解也,可与大柴胡汤下之即愈方。
柴胡(半斤) 黄芩 芍药(各三两) 半夏(半斤水洗) 大枣(十三枚擘) 生姜
(五两) 枳实(四枚
上七味切,以水一斗二升煮至六升,去滓,更煎,取三升温服一升,日三服,一方加大
黄二两,今不加大黄恐不名为大柴胡汤也。忌羊肉饧兼主天行。(千金翼肘后同)
又伤寒十三日不解,胸胁满而呕,日晡所发潮热,热毕而微利,此本柴胡证,下之不得
利,今反利者,知 以丸药下之,此非其治也,潮热者实也,先宜服小柴胡汤以解其外后以
柴胡加芒硝汤主之方。
柴胡(二两十六铢) 黄芩 人参 甘草(炙) 生姜(各一两) 半夏(五枚) 大
枣(四枚
擘) 芒硝(二合)
上八味切,以水四升,煮七味,取二升去滓,下芒硝,更上火煎一二沸,分为两服,未
解更作,忌海藻菘菜羊肉饧等。(出玉函经一方芒硝三合桑螵蛸五个大黄四分煮取一升半温
服五合微下愈本云柴胡汤再服以解其外取愈一方外加芒硝大黄桑螵蛸是也)
《素问》中黄帝问道:热病,都是属于伤寒一类的疾病,有的痊愈,有的死亡,那些死亡的都在发病后六七天之间,而痊愈的都在十天以上,这是为什么呢?岐伯回答说:巨阳经(即太阳经),是诸阳经的统领,它的经脉连接于风府穴,所以它是诸阳经的主气。人受寒邪侵袭就会患热病,热势虽然严重也不会死,但如果两感于寒(同时感受寒邪,表里同病)而患病的人必定死亡。黄帝说:我想听听它的症状表现。岐伯说:第一天,巨阳经受邪,所以出现头痛、项强、腰脊疼痛。第二天,阳明经受邪,阳明经主肌肉,其经脉夹鼻络于目,所以出现身热、目痛、鼻干、不能安卧。第三天,少阳经受邪,少阳经主胆,其经脉循行胁肋络于耳,所以出现胸胁疼痛和耳聋。三阳经的经络都受了病邪,但尚未传入内脏,所以可以通过发汗的方法治愈。第四天,太阴经受邪,太阴经分布于胃中并络于咽喉,所以出现腹部胀满和咽喉干燥。第五天,少阴经受邪,少阴经贯穿肾脏络于肺系和舌根,所以出现口燥、舌干而渴。第六天,厥阴经受邪,厥阴经循行阴器而终于肝脏,所以出现心烦腹满和睾丸收缩。如果三阴三阳、五脏六腑都受了病邪,营卫之气运行停滞,五脏气机不通,那么就会死亡。那些没有两感于寒的患者,第七天巨阳经的病势衰退,头痛减轻。第八天阳明经的病势衰退,身热减轻。第九天少阳经的病势衰退,耳聋稍微能听到声音。第十天太阴经的病势衰退,腹部胀满消退如常,开始想吃东西。第十一天少阴经的病势衰退,口渴停止,腹胀消除,舌干已愈并开始打喷嚏。第十二天厥阴经的病势衰退,睾丸松弛,少腹微降,大邪之气都已去除,病一天天好了。
黄帝说:如何治疗呢?岐伯说:治疗要分别疏通各脏腑的经脉。病势日渐衰退了,病程未满三天的,可以通过发汗治愈;病程已满三天的,可以通过泄下治愈。
又黄帝问道:两感于寒的患者,其脉象和病症表现是怎样的?岐伯说:两感于寒的患者,第一天巨阳经与少阴经同时受病,则出现头痛、口干、心烦腹满和口渴。第二天阳明经与太阴经同时受病,则出现腹部胀满、身热、不想吃东西、说胡话。第三天少阳经与厥阴经同时受病,则出现耳聋、睾丸收缩、四肢厥冷,水浆不进,神志昏迷,这样六天后就会死亡。
黄帝说:五脏已经受伤,六腑不通,营卫不行,在此之后三天才死亡,这是为什么呢?岐伯说:阳明经是十二经脉之长,气血旺盛,所以患者神志昏迷,经过三天,其气血耗尽,所以死亡。(出自第九卷,《甲乙经》《太素》相同)
病源:伤寒第一天,太阳经受病,太阳经是小肠的经脉,为三阳之首,所以先受病,其脉络于腰脊,主于头项,所以得病第一天就出现头项、背膊、腰脊疼痛。
又伤寒第二天,阳明经受病,阳明经是胃的经脉,主于肌肉,其脉络鼻入目,所以得病第二天,出现内热、鼻干、不能安眠。诸阳经在体表,表始受病在皮肤之间,所以可以用摩膏、火灸等方法发汗而愈。(出自第七卷)
张仲景《伤寒论》:伤寒一二日,心中悸动而烦乱,用小建中汤主治。方剂组成:桂心(三两)、甘草(炙二两)、生姜(三两)、大枣(十二枚,掰开)、胶饴(一升)、芍药(六两)。以上六味药切碎,用水七升,先煮前五味,取三升药液,去渣,加入胶饴,再上火微煮,令其溶解,温服一升,每日三次。如果是呕吐患者不可服用小建中汤,因为甜味故也。忌食海藻、菘菜、生葱。(《千金翼方》相同,出自第三卷)
(张仲景《伤寒论》中伤寒一二日内用麻黄汤主治,这里说用小建中汤是不对的,此方只治疗心中悸动而烦乱。)
病源:伤寒第三天,少阳经受病,少阳经是胆的经脉,其脉循行于胁上至颈耳,所以得病第三天,出现胸胁疼痛和耳聋。三阳经络刚开始相传病邪,未入于脏,所以都可以用发汗法解除。(出自第七卷)
张仲景《伤寒论》:治疗太阳病三天,发汗后,病未解,蒸蒸发热的,属于调胃承气汤证。方剂组成:甘草(炙三两)、芒硝(半升)、大黄(四两)。以上三味药切碎,用水三升,煮前二味(大黄、甘草),取一升药液,去渣,加入芒硝,再微煮至沸,温顿服,用调胃承气汤即可痊愈。忌食海藻、菘菜,《经心录》相同。(出自第十卷,张仲景《伤寒论》中三日也可服麻黄汤,这里说用调胃承气汤是不对的,此方只治疗三日发汗不解、蒸蒸发热的情况。)
病源:伤寒第四天,太阴经受病,太阴经是脾的经脉,为三阴之首,可知三天以前,阳经受病完毕,传之于阴,而太阴经受病。其脉络于脾,主于喉嗌,所以得病第四天出现腹部胀满和咽喉干燥,病位在胸膈,所以可以用吐法治愈。
又伤寒第五天,少阴经受病,少阴经是肾的经脉,其脉贯肾络肺系于舌,所以得病第五天,出现口燥、舌干、口渴想喝水,病位在腹,所以可以用下法治愈。(均出自第七卷)
张仲景《伤寒论》:伤寒四五日,身热、恶风、颈项强直、胁下满闷、手足温暖而口渴的,用小柴胡汤主治。方剂组成:柴胡(半斤)、栝蒌根(四两)、桂心(三两)、黄芩(三两)、牡蛎(三两)、甘草(炙二两)、干姜(三两)。以上七味药切碎,用水一斗二升,煮取六升,去渣,再煎取三升,温服一升,每日三次。初服后微微烦闷,温覆取汗出的就好了。忌食生葱、海藻、菘菜。(范汪方相同,出自第三卷,张仲景《伤寒论》名为柴胡姜桂汤,合用柴胡、人参、甘草、黄芩、半夏、生姜、大枣七味,就是小柴胡汤,《玉函经》《千金翼方》相同。)
病源:伤寒第六天,厥阴经受病,厥阴经是肝的经脉,其脉循行阴器络于肝,所以得病第六天出现心烦腹满和睾丸收缩。这则是阴阳俱受病,毒瓦斯在胸,所以可以用下法治愈。
又伤寒第七天,太阳经病衰,头痛稍减。伤寒七日病法应当小愈,因为阴阳诸经传遍的缘故。现在七日以后,病反而加重不除的,是想成为再经病(重复传经)。再经病者,是阴阳诸经络再次受病的缘故。(均出自第七卷)
张仲景《伤寒论》:治疗伤寒不大便六七日,头痛有发热,给予承气汤。其人小便反清亮的,知道病不在里,仍在表,应当需要发汗。如果头痛的必定流鼻血,宜用桂枝汤。方剂组成:桂枝、芍药(各三两)、甘草(炙二两)、生姜(三两)、大枣(十二枚,掰开)。以上五味药切碎,用水七升,煮取三升,去渣,温服一升,须臾喝稀粥一升以助药力,覆盖取微汗。忌食生葱、海藻、菘菜。(《集验方》《备急文仲》《范汪方》相同,张仲景《伤寒论》认为此方六七日病在表者可服之。)
又伤寒五六日,呕而发热者,柴胡汤证具备,如果用其他药物攻下,柴胡证仍在,所以可以给予柴胡汤。此虽已攻下不为逆,必然会出现蒸蒸而振栗,随后发热汗出而解。
病源:伤寒第八天,阳明经病衰,身热稍减。伤寒八日,病不解的,或者是诸阴阳经络再次受病,或者是因为发汗、吐、下之后,毒瓦斯未尽,所以病证犹存。
又伤寒第九天,少阳经病衰,耳聋稍微能听到声音。伤寒九日以上病不除的,或者初一经受病,即不能相传,或者已传三阳完毕,而不能传于阴,导致停滞数日,病证不罢的,或者三阳三阴传病已毕,又重感于寒,所以日数多而病候改变。(出自第七卷)
张仲景《伤寒论》:治疗伤寒八九日,风湿相搏,身体疼痛而烦,不能自转侧,不呕不渴,下之脉浮虚而涩的,属于桂枝附子汤证。若大便硬,小便自利的,属于附子白术汤证。
桂枝附子汤方:桂心(四两)、附子(三枚,炮去皮)、生姜(三两)、甘草(二两,炙)、大枣(十二枚,掰开)。以上五味药切碎,用水六升,煮取二升,去渣,温分三次服。忌食生葱、猪肉、海藻、菘菜。
附子白术汤方:白术(四两)、大枣(十二枚)、甘草(炙一两)、生姜(二两)、附子(三枚,炮去皮,四破)。以上五味药切碎,用水六升,煮取二升,去渣,温分三次服。初一服后其身如痹,半日许复服之,都尽后,其人如冒状者勿怪,这是因为附子、术并走皮中逐水气未除,所以使人如冒状也。原本云附子一枚,今加之二枚,名附子汤。忌葱、猪肉、菘菜、海藻、桃李、雀肉等。(《千金翼方》相同,出自第十一卷,张仲景论法当加桂枝四两,此本一方二法,以大便硬、小便自利故去桂枝,以大便不硬、小便不利当加桂枝附子。)
病源:伤寒第十天,太阴经病衰,腹部胀满消退如常,则思饮食。第十一天少阴经病衰,口渴停止,腹胀消除,舌干已愈而打喷嚏。第十二天,厥阴经病衰,睾丸松弛,少腹微降,大气皆去,病一天天好了。(出自第七卷,《素问》《太素》《甲乙经》并同。)
张仲景《伤寒论》:治疗吐下之后,不大便,五日至十余日,日晡所发潮热,不恶寒,独语如见鬼状,若剧者发则不识人,循衣摸床,惕而不安,微喘,但发热谵语的,属于大承气汤证。方剂组成:大黄(去皮四两)、陈枳实(炙五枚)、芒硝(三合)、浓朴(半斤)。以上四味药切碎,用水一斗,先煮枳实、厚朴二物,取五升,去渣,纳大黄煮取二升,去渣,纳芒硝煮一二沸,分为两服,初一服便得利者止,后服不必尽剂。(《千金方》及《千金翼方》相同,出自第五卷。)
又太阳病过经十余日,及二三下之后,四五日柴胡证仍在的,先与小柴胡汤,呕不止,心下急(一说呕止小安),郁郁微烦的,为未解也,可与大柴胡汤下之即愈。方剂组成:柴胡(半斤)、黄芩、芍药(各三两)、半夏(半斤,水洗)、大枣(十三枚,掰开)、生姜(五两)、枳实(四枚)。以上七味药切碎,用水一斗二升煮至六升,去渣,再煎,取三升,温服一升,每日三次。一方加大黄二两,现在不加大黄,恐怕不名为大柴胡汤。忌羊肉、饧,兼主天行(时行疫病)。(《千金翼方》《肘后备急方》相同。)
又伤寒十三日不解,胸胁满而呕,日晡所发潮热,热毕而微利,此本柴胡证,下之不得利,今反利的,知是以丸药下之,此非其治也,潮热者实也,先宜服小柴胡汤以解其外,后以柴胡加芒硝汤主治。方剂组成:柴胡(二两十六铢)、黄芩、人参、甘草(炙)、生姜(各一两)、半夏(五枚)、大枣(四枚,掰开)、芒硝(二合)。以上八味药切碎,用水四升,煮七味,取二升,去渣,下芒硝,更上火煎一二沸,分为两服,未解更作。忌海藻、菘菜、羊肉、饧等。(出自《玉函经》,一方芒硝三合、桑螵蛸五个、大黄四分,煮取一升半,温服五合,微下愈。原本云柴胡汤再服以解其外取愈,一方外加芒硝、大黄、桑螵蛸是也。)
In the *Suwen* (Basic Questions), the Yellow Emperor asked: Heat diseases are all of the category of Cold Damage (Shanghan). Some recover, some die. Those who die do so within six or seven days, while those who recover take more than ten days. Why is this? Qibo replied: Juyang (Great Yang, i.e., Taiyang) is the leader of all Yang meridians. Its vessels connect to the Fengfu acupoint, thus it governs the Qi of all Yang meridians. When humans are injured by cold pathogens, they develop heat diseases. Even if the heat is severe, death will not occur. However, those who suffer from "Lianggan" (simultaneous contraction of cold on both exterior and interior) will inevitably die. The Emperor said: I wish to hear about their manifestations. Qibo said: On the first day, Juyang receives the pathogen, resulting in headache, stiffness of the neck and back, and pain in the waist and spine. On the second day, Yangming receives the pathogen. Yangming governs the muscles; its vessels run alongside the nose and connect to the eyes. Thus, there is body heat, eye pain, dry nose, and inability to lie down. On the third day, Shaoyang receives the pathogen. Shaoyang governs the Gallbladder; its vessels follow the costal region and connect to the ears. Thus, there is pain in the chest and hypochondrium, and deafness. When the meridians of the three Yang channels are all affected but the disease has not entered the Zang organs, it can be cured by sweating. On the fourth day, Taiyin receives the pathogen. Taiyin vessels distribute in the stomach and connect to the throat. Thus, there is abdominal fullness and dry throat. On the fifth day, Shaoyin receives the pathogen. Shaoyin vessels pass through the Kidney, connect to the Lung system and the root of the tongue. Thus, there is dry mouth, dry tongue, and thirst. On the sixth day, Jueyin receives the pathogen. Jueyin vessels follow the genitalia and end at the Liver. Thus, there is irritability, fullness, and retraction of the scrotum. If the three Yin and three Yang, as well as the five Zang and six Fu organs, are all diseased, Ying and Wei Qi cease to circulate, and the five Zang organs become blocked, death ensues. For those not suffering from Lianggan, on the seventh day, the disease in Juyang declines, and the headache slightly improves. On the eighth day, the disease in Yangming declines, and body heat slightly subsides. On the ninth day, the disease in Shaoyang declines, and hearing slightly returns. On the tenth day, the disease in Taiyin declines, abdominal distension reduces to normal, and appetite returns. On the eleventh day, the disease in Shaoyin declines, thirst stops, fullness resolves, dry tongue heals, and sneezing occurs. On the twelfth day, the disease in Jueyin declines, the scrotum relaxes, the lower abdomen slightly descends, the great pathogenic qi departs, and the illness gradually cures.
The Emperor asked: How should it be treated? Qibo replied: Treatment requires unblocking the meridians of each respective organ. As the disease declines day by day, if the duration is less than three days, it can be cured by sweating; if the duration is three days or more, it can be cured by purging.
Again, the Emperor asked: What are the pulse and clinical manifestations for those with Lianggan? Qibo replied: In cases of Lianggan, on the first day, both Juyang and Shaoyin are diseased, presenting with headache, dry mouth, irritability, fullness, and thirst. On the second day, both Yangming and Taiyin are diseased, presenting with abdominal fullness, body heat, anorexia, and delirium. On the third day, both Shaoyang and Jueyin are diseased, presenting with deafness, scrotal retraction, cold extremities, inability to swallow fluids, and unconsciousness. Death occurs after six days.
The Emperor asked: The five Zang organs are damaged, the six Fu organs are blocked, Ying and Wei Qi do not circulate. After this, death occurs three days later. Why? Qibo replied: Yangming is the head of the twelve meridians, and its Qi and Blood are abundant. Therefore, the patient becomes unconscious. After three days, its Qi is exhausted, hence death. (From Volume 9; identical in *Jiayijing* and *Taisu*.)
Pathogenesis: On the first day of Cold Damage, the Taiyang channel is affected. Taiyang is the meridian of the Small Intestine and the chief of the three Yang channels, so it is affected first. Its vessels connect to the waist and spine and govern the head and neck. Therefore, on the first day of illness, there is pain in the head, neck, back, shoulders, waist, and spine.
Furthermore, on the second day of Cold Damage, the Yangming channel is affected. Yangming is the meridian of the Stomach and governs the muscles. Its vessels connect to the nose and enter the eyes. Therefore, on the second day, there is internal heat, dry nose, and insomnia. All Yang channels are on the exterior; when the exterior is initially attacked, the pathogen lies between the skin and hair. Thus, it can be cured by applying ointments, moxibustion, or inducing sweating. (From Volume 7.)
Zhang Zhongjing's *Shanghan Lun*: In Cold Damage during the first or second day, if there is palpitation and irritability, Xiaojianzhong Tang (Minor Construct the Middle Decoction) is the primary formula. Ingredients: Guixin (Cinnamon Twig, 3 liang), Gancao (Licorice Root, prepared, 2 liang), Shengjiang (Fresh Ginger, 3 liang), Dazao (Jujube, 12 pieces, split), Jiaoyi (Maltose, 1 sheng), Shaoyao (Peony Root, 6 liang). Cut the above six ingredients. Add 7 sheng of water, decoct the first five ingredients to obtain 3 sheng, remove the dregs, add the maltose, and simmer gently over fire until dissolved. Take 1 sheng warm, three times a day. Patients prone to vomiting should not take Xiaojianzhong Tang due to its sweetness. Avoid Seaweed, Chinese Cabbage, and raw Green Onion. (*Qianjin Yifang* is identical; From Volume 3.)
(Note: Zhang Zhongjing's *Shanghan Lun* states that Mahuang Tang (Ephedra Decoction) should be used for Cold Damage on the first or second day. Saying Xiaojianzhong Tang is incorrect here; this formula only treats palpitation and irritability.)
Pathogenesis: On the third day of Cold Damage, the Shaoyang channel is affected. Shaoyang is the meridian of the Gallbladder. Its vessels follow the hypochondrium up to the neck and ears. Therefore, on the third day, there is pain in the chest and hypochondrium, and deafness. The transmission of disease among the meridians of the three Yang channels begins; since it has not entered the Zang organs, it can be resolved by sweating. (From Volume 7.)
Zhang Zhongjing's *Shanghan Lun*: Treating Taiyang disease for three days, if sweating fails to resolve the condition and there is steaming heat, it belongs to the Tiaowei Chengqi Tang (Regulate the Stomach and Order the Qi Decoction) pattern. Ingredients: Gancao (Licorice Root, prepared, 3 liang), Mangxiao (Mirabilite, half sheng), Dahuang (Rhubarb Root, 4 liang). Cut the above three ingredients. Add 3 sheng of water, decoct the two items (Dahuang and Gancao) to obtain 1 sheng, remove the dregs, add Mangxiao, and boil gently until bubbling. Take warm in one dose. Tiaowei Chengqi Tang will cure it. Avoid Seaweed and Chinese Cabbage. (*Jingxinlu* is identical; From Volume 10. Note: Zhang Zhongjing's *Shanghan Lun* also allows Mahuang Tang on the third day; stating Tiaowei Chengqi Tang is incorrect here unless treating steaming heat after failed sweating on the third day.)
Pathogenesis: On the fourth day of Cold Damage, the Taiyin channel is affected. Taiyin is the meridian of the Spleen and the chief of the three Yin channels. It is known that before the third day, Yang channels were affected, then transmitted to Yin, affecting Taiyin. Its vessels connect to the Spleen and govern the throat. Therefore, on the fourth day, there is abdominal fullness and dry throat. The disease is located in the chest and diaphragm, so it can be cured by emesis.
Furthermore, on the fifth day of Cold Damage, the Shaoyin channel is affected. Shaoyin is the meridian of the Kidney. Its vessels pass through the Kidney, connect to the Lung system and the tongue. Therefore, on the fifth day, there is dry mouth, dry tongue, thirst, and desire to drink. The disease is located in the abdomen, so it can be cured by purgation. (Both from Volume 7.)
Zhang Zhongjing's *Shanghan Lun*: In Cold Damage on the fourth or fifth day, if there is body heat, aversion to wind, stiff neck, fullness under the ribs, warm hands and feet, and thirst, Xiaochaihu Tang (Minor Bupleurum Decoction) is the primary formula. Ingredients: Chaihu (Bupleurum Root, half jin), Gualougen (Trichosanthes Root, 4 liang), Guixin (Cinnamon Twig, 3 liang), Huangqin (Scutellaria Root, 3 liang), Muli (Oyster Shell, 3 liang), Gancao (Licorice Root, prepared, 2 liang), Jiangjiang (Dried Ginger, 3 liang). Cut the above seven ingredients. Add 12 sheng of water, decoct to obtain 6 sheng, remove dregs, and decoct again to obtain 3 sheng. Take 1 sheng warm, three times a day. Initially, slight irritability may occur; covering warmly to induce sweating will lead to recovery. Avoid raw Green Onion, Seaweed, and Chinese Cabbage. (Fan Wang's formula is identical; From Volume 3. Zhang Zhongjing's *Shanghan Lun* names this Chaihu Jianggui Tang. Combined with Renshen, Gancao, Huangqin, Banxia, Shengjiang, and Dazao, these seven ingredients constitute Xiaochaihu Tang. *Yuhan Jing* and *Qianjin Yifang* are identical.)
Pathogenesis: On the sixth day of Cold Damage, the Jueyin channel is affected. Jueyin is the meridian of the Liver. Its vessels follow the genitalia and connect to the Liver. Therefore, on the sixth day, there is irritability, fullness, and scrotal retraction. This indicates that both Yin and Yang are diseased, and toxic factors are in the chest. Thus, it can be cured by purgation.
Furthermore, on the seventh day of Cold Damage, the Taiyang disease declines, and the headache slightly improves. According to the law of Cold Damage, the disease should slightly improve on the seventh day because the transmission through all Yin and Yang channels is complete. If after the seventh day the disease worsens and does not resolve, it indicates a recurrence of transmission (Rejing). Recurrence means the meridians of Yin and Yang have been affected again. (Both from Volume 7.)
Zhang Zhongjing's *Shanghan Lun*: Treating Cold Damage with constipation for six or seven days, accompanied by headache and fever, administer Chengqi Tang. If the urine is clear, it indicates the disease is not in the interior but remains in the exterior, requiring sweating. If there is headache, epistaxis (nosebleed) will likely occur; Guizhi Tang (Cinnamon Twig Decoction) is appropriate. Ingredients: Guizhi (Cinnamon Twig), Shaoyao (Peony Root, 3 liang each), Gancao (Licorice Root, prepared, 2 liang), Shengjiang (Fresh Ginger, 3 liang), Dazao (Jujube, 12 pieces, split). Cut the above five ingredients. Add 7 sheng of water, decoct to obtain 3 sheng, remove dregs. Take 1 sheng warm. Shortly after, drink 1 sheng of thin rice gruel to assist the medicinal power. Cover to induce slight sweating. Avoid raw Green Onion, Seaweed, and Chinese Cabbage. (*Jiyan Fang*, *Beiji Wenzhong*, and *Fan Wang* are identical. Zhang Zhongjing's *Shanghan Lun* states this formula can be taken when the disease is in the exterior on the sixth or seventh day.)
Furthermore, in Cold Damage on the fifth or sixth day, if there is vomiting and fever, the Chaihu Tang syndrome is complete. If purgatives were incorrectly administered, but the Chaihu syndrome persists, Chaihu Tang can still be given. Although purgation has occurred, it is not a counteraction. There will inevitably be chills followed by fever and sweating, leading to resolution.
Pathogenesis: On the eighth day of Cold Damage, the Yangming disease declines, and body heat slightly subsides. If the disease does not resolve by the eighth day, it may be due to repeated infection of the Yin and Yang meridians, or because toxic factors remain after sweating, emesis, or purgation, so symptoms persist.
Furthermore, on the ninth day of Cold Damage, the Shaoyang disease declines, and hearing slightly returns. If the disease does not resolve after the ninth day, it may be because the initial channel infection did not transmit, or transmission through the three Yang was completed but did not proceed to Yin, causing stagnation for several days. Alternatively, after transmission through all three Yin and three Yang is complete, a secondary contraction of cold occurs, leading to prolonged duration and changing symptoms. (From Volume 7.)
Zhang Zhongjing's *Shanghan Lun*: Treating Cold Damage on the eighth or ninth day where Wind-Dampness intertwines, causing body pain and irritability, inability to turn over, no vomiting, no thirst, and a floating, deficient, and choppy pulse after purgation, belongs to the Guizhi Fuzi Tang (Cinnamon Twig and Aconite Decoction) pattern. If the stool is hard and urination is free, it belongs to the Fuzi Baizhu Tang (Aconite and Atractylodes Macrocephala Decoction) pattern.
Guizhi Fuzi Tang Formula: Guixin (Cinnamon Twig, 4 liang), Fuzi (Prepared Aconite Root, 3 pieces, roasted and peeled), Shengjiang (Fresh Ginger, 3 liang), Gancao (Licorice Root, 2 liang, prepared), Dazao (Jujube, 12 pieces, split). Cut the above five ingredients. Add 6 sheng of water, decoct to obtain 2 sheng, remove dregs. Divide into three warm doses. Avoid raw Green Onion, pork, Seaweed, and Chinese Cabbage.
Fuzi Baizhu Tang Formula: Baizhu (Atractylodes Macrocephala Rhizome, 4 liang), Dazao (Jujube, 12 pieces), Gancao (Licorice Root, 1 liang, prepared), Shengjiang (Fresh Ginger, 2 liang), Fuzi (Prepared Aconite Root, 3 pieces, roasted, peeled, and cut into four). Cut the above five ingredients. Add 6 sheng of water, decoct to obtain 2 sheng, remove dregs. Divide into three warm doses. After the first dose, the body may feel numb. Half a day later, if the remaining dose is taken and the patient feels dizzy, do not be alarmed. This is because Fuzi and Baizhu move through the skin to expel water dampness which has not yet been cleared. Originally, one piece of Fuzi was used; now two are added, naming it Fuzi Tang. Avoid Green Onion, pork, Chinese Cabbage, Seaweed, peaches, plums, and sparrow meat. (*Qianjin Yifang* is identical; From Volume 11. Zhang Zhongjing's method suggests adding Guizhi 4 liang. This text presents one formula with two methods: removing Guizhi due to hard stool and free urination; adding Guizhi and Fuzi if stool is not hard and urination is difficult.)
Pathogenesis: On the tenth day of Cold Damage, the Taiyin disease declines, abdominal fullness reduces to normal, and appetite returns. On the eleventh day, the Shaoyin disease declines, thirst stops, fullness resolves, dry tongue heals, and sneezing occurs. On the twelfth day, the Jueyin disease declines, the scrotum relaxes, the lower abdomen slightly descends, the great pathogenic qi departs, and the illness gradually cures. (From Volume 7; identical in *Suwen*, *Taisu*, and *Jiayijing*.)
Zhang Zhongjing's *Shanghan Lun*: Treating post-emetic/purgative constipation lasting five to ten-plus days, with tidal fever in the late afternoon, no aversion to cold, talking alone as if seeing ghosts, and in severe cases, unconsciousness, grasping at clothes and bedrails, restlessness, slight wheezing, and only fever with delirium, belongs to the Dachengqi Tang (Major Order the Qi Decoction) pattern. Ingredients: Dahuang (Rhubarb Root, peeled, 4 liang), Chen Zhishi (Aged Immature Bitter Orange, roasted, 5 pieces), Mangxiao (Mirabilite, 3 he), Houpo (Magnolia Bark, half jin). Cut the above four ingredients. Add 10 sheng of water, decoct the first two (Zhishi and Houpo) to obtain 5 sheng, remove dregs, add Dahuang, decoct to obtain 2 sheng, remove dregs, add Mangxiao, boil for one or two boils. Divide into two doses. If bowel movement occurs after the first dose, stop taking it; the second dose need not be finished. (*Qianjin Fang* and *Qianjin Yifang* are identical; From Volume 5.)
Furthermore, if Taiyang disease has passed its stage for more than ten days, and after two or three purgations, the Chaihu syndrome persists on the fourth or fifth day, first administer Xiaochaihu Tang. If vomiting continues, urgency in the epigastrium (or relief of vomiting with slight comfort), and mild depression/irritability indicate the disease is unresolved. Dachengchaihu Tang (Major Bupleurum Decoction) can be administered to purge, leading to cure. Ingredients: Chaihu (Bupleurum Root, half jin), Huangqin (Scutellaria Root), Shaoyao (Peony Root, 3 liang each), Banxia (Pinellia Tuber, half jin, washed), Dazao (Jujube, 13 pieces, split), Shengjiang (Fresh Ginger, 5 liang), Zhishi (Immature Bitter Orange, 4 pieces). Cut the above seven ingredients. Add 12 sheng of water, decoct to 6 sheng, remove dregs, decoct again to obtain 3 sheng. Take 1 sheng warm, three times a day. One variant adds Dahuang 2 liang; currently, Dahuang is not added, lest it no longer be named Dachengchaihu Tang. Avoid mutton and maltose. Also treats epidemic febrile diseases. (*Qianjin Yifang* and *Zhouhou Beiji Fang* are identical.)
Furthermore, if Cold Damage persists for thirteen days without resolution, with fullness in the chest and hypochondrium, vomiting, tidal fever in the late afternoon, and slight diarrhea after the fever subsides, this is originally a Chaihu syndrome. Purging should not cause diarrhea; if it does, it is known that pill-based purgatives were used, which is incorrect treatment. Tidal fever indicates excess. First, administer Xiaochaihu Tang to resolve the exterior, then treat with Chaihu Jia Mangxiao Tang (Bupleurum Decoction plus Mirabilite). Ingredients: Chaihu (2 liang 16 zhu), Huangqin (Scutellaria Root), Renshen (Ginseng Root), Gancao (Licorice Root, prepared), Shengjiang (Fresh Ginger, 1 liang each), Banxia (Pinellia Tuber, 5 pieces), Dazao (Jujube, 4 pieces, split), Mangxiao (Mirabilite, 2 he). Cut the above eight ingredients. Add 4 sheng of water, decoct the seven ingredients to obtain 2 sheng, remove dregs, add Mangxiao, boil for one or two boils. Divide into two doses. If unresolved, prepare another batch. Avoid Seaweed, Chinese Cabbage, mutton, and maltose. (From *Yuhan Jing*. One variant: Mangxiao 3 he, Sangpiaoxiao (Mantis Egg Case) 5 pieces, Dahuang 4 fen, decoct in water to obtain 1.5 sheng, take 5 he warm, slight purgation leads to cure. Originally stated: take Chaihu Tang twice to resolve the exterior. Another variant adds Mangxiao, Dahuang, and Sangpiaoxiao.)