《巢氏病源》寒疟候∶此由阴阳相并，阳虚则阴胜，阴胜则寒。寒发于内而并于外，所以内外俱寒，故病发
但战栗而鼓颔颐也。
《全生指迷》论大人、小儿疟疾∶若寒从背起，冷大如手，不甚战栗，似欲发热而汗出；或即头痛呕吐时作，
其脉迟小。此由脾胃素弱，因气寒而收聚，水谷不能克化，变而成痰。伏痰在内，阴上乘阳，阳为阴所乘，所
以作寒逼而成汗。宜服旋复花丸、半硫丸。（方并见本门。）
《圣惠》治大人、小儿寒疟不止。雄黄丸方
雄黄 硫黄 朱砂 桂心（末） 干姜（生用） 巴豆（去皮、心，以水二升煮水尽，压去油，
研如面。各一分） 麝香（半两） 阿魏（半分）
上件药相和，研令匀细，以醋煮面糊为丸如梧桐子大。未发前，以绵子裹一丸安在两耳中，及男左女右，
以绵帛系一粒于臂上。一粒可治七人。
《圣惠》治大人、小儿寒疟，手足鼓颤，心寒面青。宜用此方。
朱砂（细研） 虎头骨 猢狲头骨 砒霜 天灵盖 阿魏 安息香（以上各半两）
上件药生捣，罗为末，入朱砂研匀，于端午日午时，用白团和丸如豌豆大。男左女右，手把一丸定后，用
绯绢袋子系于中指上，若登溷，即暂解却。一丸可治七人。
《圣惠》又方
独头蒜（一颗） 黄丹（半两）
上件药相和，五月五日午时同捣一千杵，丸如黑豆大。候发时，以温茶下二丸。小儿粟米大一丸。
《圣惠》治大人、小儿寒疟，阳虚阴盛，内外俱寒，四肢颤掉。常山丸方
常山（半两） 臭黄 雌黄（各细研） 猢狲头骨 天灵盖 虎头骨 安息香 朱砂 野狸
头骨 砒霜 乳香 阿魏 白芥子（各一分） 绿豆
上件药并生用，捣、罗为末，用软饭和捣三、二百杵，丸如梧桐子大。修合之时，勿令孝子、女人知，五
月五日午时合为妙。如缓急，即不择日辰合。未发时，以绛囊盛，于中指上系一丸，男左女右。三日如不住，
以热水服一丸，立效。有娠妇人及小儿不得服，只得带。忌食热物。
张涣乌梅丹方 治小儿发寒热甚者。
乌梅肉（一两，炒干） 母丁香 干漆（微炒） 当归 桂心（各半两。以上捣，罗为细末，次入
麝） 麝香（一分，研细）
上件拌匀，炼蜜和丸如黍米大。每服十粒，粥饮下。量儿大小加减。
《全生指迷》旋复花丸
旋复花 桂心 枳实（麸炒） 人参（各五分） 干姜 芍药 白术（各六分） 茯苓 野狼毒 乌
头（泡，去皮） 矾石（火 一伏时。各八分）
细辛（去苗） 大黄（湿纸裹煨） 黄芩 葶苈（炒） 浓朴（去皮，姜汁炙） 吴茱萸（炒） 芫
花（炒） 橘皮（洗。各四分） 甘遂（三分，炒）
上为细末，炼蜜和丸如梧子大。米饮下三丸，未知加至七丸。小儿黄米大二丸。
《全生指迷》半硫丸
半夏（三两，汤洗七遍） 硫黄（二两，研飞）
上为末，生姜汁煮面糊丸如桐子大。每服三十丸，米饮下，不计时候。小儿黍米大三、五丸。
《巢氏病源》中关于寒疟的论述：这是由于阴阳相互搏结，阳气虚弱则阴气偏盛，阴气偏盛则产生寒象。寒气从体内发出并外达体表，因此内外都感到寒冷，所以发病时只是战栗且鼓动下巴和面颊。
《全生指迷》讨论成人和小儿的疟疾：如果寒气从背部升起，冷感大如手掌大小，战栗不明显，似乎要发热但随即出汗；或者立即出现头痛、呕吐且发作有时，脉象迟而细小。这是由脾胃素来虚弱，因气寒而收敛聚结，水谷不能消化，变化而成痰饮。伏留的痰饮在体内，阴邪上乘于阳位，阳气被阴邪所乘，所以产生寒象并逼迫津液外泄成为汗出。适宜服用旋复花丸、半硫丸。（方剂均见本门。）
《圣惠方》治疗成人、小儿寒疟不止的雄黄丸方
雄黄 硫黄 朱砂 桂心（研末） 干姜（生用） 巴豆（去皮、心，用水二升煮至水尽，压榨去油，研成粉末。各一分） 麝香（半两） 阿魏（半分）
以上药物混合，研磨均匀细腻，用醋煮面糊制作成梧桐子大小的药丸。未发作前，用棉球包裹一丸放入双耳中，以及男性左耳、女性右耳，用棉帛系一粒在手臂上。一丸可以治疗七人。
《圣惠方》治疗成人、小儿寒疟，手足颤抖，心中寒冷面色青紫。适宜使用此方。
朱砂（细研） 虎头骨 猴头骨 砒霜 天灵盖 阿魏 安息香（以上各半两）
以上药物生捣，过筛为末，加入朱砂研匀，在端午日午时，用白团药和丸如豌豆大小。男性左手、女性右手，手持一丸定神后，用红绢袋子系在中指上，若上厕所，就暂时解开。一丸可以治疗七人。
《圣惠方》又一方
独头蒜（一颗） 黄丹（半两）
以上药物混合，五月五日午时共同捣一千杵，制成黑豆大小的药丸。等待发作时，用温茶送服二丸。小儿粟米大一丸。
《圣惠方》治疗成人、小儿寒疟，阳气虚弱阴气盛，内外俱寒，四肢颤抖。常山丸方
常山（半两） 臭黄 雌黄（各细研） 猴头骨 天灵盖 虎头骨 安息香 朱砂 野狸头骨 砒霜 乳香 阿魏 白芥子（各一分） 绿豆
以上药物均生用，捣碎、过筛为末，用软饭和捣三、二百杵，制成梧桐子大小的药丸。配制时，不要让孝子、女人知道，五月五日午时配制最为妙。如有缓急，就不择日期配制。未发作时，用红色囊袋盛装，系在中指上，男性左、女性右。三天如不停止，用热水送服一丸，立刻见效。孕妇及小儿不得服用，只能佩戴。忌食热物。
张涣乌梅丹方 治疗小儿发寒热严重的。
乌梅肉（一两，炒干） 母丁香 干漆（微炒） 当归 桂心（各半两。以上捣碎，过筛为细末，再次加入麝香） 麝香（一分，研细）
以上拌匀，炼蜜和丸如黍米大小。每次服用十粒，粥饮送下。根据孩子大小加减剂量。
《全生指迷》旋复花丸
旋复花 桂心 枳实（麸炒） 人参（各五分） 干姜 芍药 白术（各六分） 茯苓 野狼毒 乌头（泡，去皮） 矾石（火烧一伏时。各八分）
细辛（去苗） 大黄（湿纸裹煨） 黄芩 葶苈（炒） 浓朴（去皮，姜汁炙） 吴茱萸（炒） 芫花（炒） 橘皮（洗。各四分） 甘遂（三分，炒）
以上为细末，炼蜜和丸如梧子大小。米饮送下三丸，无效加至七丸。小儿黄米大二丸。
《全生指迷》半硫丸
半夏（三两，汤洗七遍） 硫黄（二两，研飞）
以上为末，生姜汁煮面糊丸如桐子大小。每次服用三十丸，米饮送下，不限时候。小儿黍米大三、五丸。
Chao Shi Bing Yuan (Source of Diseases by Chao Yuanfang) on the Cold Malaria Syndrome: This arises from the intermingling of Yin and Yang. When Yang Qi is deficient, Yin prevails; when Yin prevails, cold manifests. Cold originates internally and merges externally, resulting in coldness both inside and out. Therefore, during an attack, there is merely shivering and trembling of the jaw and cheeks.
Quan Sheng Zhi Mi (Complete Life Guide to Enigma) discusses malaria in adults and children: If coldness rises from the back, feeling as large as a hand, with slight shivering, resembling a desire to fever but accompanied by sweating; or if headache and vomiting occur intermittently, with a slow and small pulse. This is due to inherent weakness of the Spleen and Stomach, where Qi becomes cold and gathers, preventing the digestion and transformation of water and grain, which transforms into phlegm. Latent phlegm resides internally, and Yin pathogen attacks Yang. Since Yang is overcome by Yin, coldness is forced, driving sweat out. It is appropriate to administer Xuanfu Hua Wan (Inula Flower Pill) and Banshu Wan (Pinellia-Sulfur Pill). (Formulas are found in this section.)
Sheng Hui Fang (Holy Benefit Formulary) treats persistent cold malaria in adults and children. Xionghuang Wan (Realgar Pill) Formula:
Xionghuang (Realgar), Liuhuang (Sulfur), Zhusha (Cinnabar), Guixin (Cinnamon Twig, powdered), Ganjiang (Dried Ginger, raw), Badou (Croton Seed, peeled, heart removed, boiled in two sheng of water until dry, pressed to remove oil, ground into powder. Each one fen), Shexiang (Musk, half liang), Awèi (Asafoetida, half fen).
Mix the above ingredients, grind until uniform and fine. Use vinegar-boiled wheat paste to form pills the size of paulownia seeds. Before the onset of symptoms, wrap one pill in cotton and place it in both ears, specifically the left ear for males and the right ear for females. Tie another pill to the arm with cotton cloth. One pill can treat seven people.
Sheng Hui Fang treats cold malaria in adults and children, characterized by trembling of hands and feet, cold sensation in the heart, and bluish complexion. The following formula is suitable:
Zhusha (Cinnabar, finely ground), Hutougu (Tiger Skull Bone), Husuntougu (Monkey Skull Bone), Pishuang (Arsenic Trioxide), Tianlinggai (Human Skull Cap), Awèi (Asafoetida), Anshixiang (Benzoin Resin). (Each half liang).
Grind the above ingredients raw, sieve into powder, mix evenly with Zhusha. On the noon hour of the Duanwu Festival (5th day of the 5th lunar month), use white dough to form pills the size of pea seeds. Hold one pill firmly in the left hand for males and right hand for females, then tie it to the middle finger using a crimson silk pouch. Remove temporarily when using the toilet. One pill can treat seven people.
Another formula from Sheng Hui Fang:
Doutousuan (Single-clove Garlic, one bulb), Huangdan (Red Lead, half liang).
Mix the above ingredients and pound together one thousand times at noon on the 5th day of the 5th lunar month. Form pills the size of black beans. When the malaria strikes, swallow two pills with warm tea. For children, one pill the size of millet grain.
Sheng Hui Fang treats cold malaria in adults and children, characterized by Yang deficiency and Yin excess, coldness inside and out, and trembling of limbs. Changshan Wan (Dichroa Root Pill) Formula:
Changshan (Dichroa Root, half liang), Chouhuang (Orpiment), Cihuang (Realgar, each finely ground), Husuntougu (Monkey Skull Bone), Tianlinggai (Human Skull Cap), Hutougu (Tiger Skull Bone), Anshixiang (Benzoin Resin), Zhusha (Cinnabar), Yeli tougu (Wild Cat Skull Bone), Pishuang (Arsenic Trioxide), Ruxiang (Frankincense), Awèi (Asafoetida), Baijiezi (White Mustard Seed, each one fen), Lüdou (Mung Bean).
Use all ingredients raw. Pound and sieve into powder. Mix with soft rice and pound three to two hundred times. Form pills the size of paulownia seeds. During preparation, do not let filial sons or women know. It is best to prepare on the noon hour of the 5th day of the 5th lunar month. In emergencies, any time is acceptable. Before onset, store in a crimson pouch and tie one pill to the middle finger (left for males, right for females). If symptoms persist for three days, take one pill with hot water for immediate effect. Pregnant women and children must not ingest it, only wear it. Avoid hot foods.
Zhang Huan's Wumei Dan (Mume Fruit Elixir) treats severe chills and fever in children.
Wumei Rou (Mume Fruit Flesh, one liang, stir-fried until dry), Mudingxiang (Mother Clove), Ganqi (Dried Lacquer), Danggui (Angelica Sinensis), Guixin (Cinnamon Twig, each half liang). (Pound and sieve the above into fine powder, then add Musk). Shexiang (Musk, one fen, finely ground).
Mix well, combine with refined honey to form pills the size of millet grains. Take ten pills per dose, washed down with gruel broth. Adjust dosage according to the child's age and size.
Quan Sheng Zhi Mi Xuanfu Hua Wan (Inula Flower Pill):
Xuanfuhua (Inula Flower), Guixin (Cinnamon Twig), Zhishi (Immature Bitter Orange, bran-fried), Renshen (Ginseng, each five fen), Ganjiang (Dried Ginger), Shaoyao (Peony Root), Baizhu (Atractylodes Macrocephala, each six fen), Fuling (Poria), Yelangdu (Stemona Root), Wutou (Aconite Root, soaked, peeled), Fanshi (Alum, fired for one fu period, each eight fen).
Xixin (Asarum, de-rooted), Dahuang (Rhubarb Root, wrapped in wet paper and baked), Huangqin (Scutellaria Root), Tingli (Lepidium Seed, fried), Houpo (Magnolia Bark, peeled, ginger-juice processed), Wuzhuyu (Evodia Fruit, fried), Yuanhua (Genkwa Flower, fried), Jupi (Citrus Peel, washed, each four fen), Gansui (Kansui Root, three fen, fried).
Grind into fine powder. Combine with refined honey to form pills the size of paulownia seeds. Take three pills with rice drink; if ineffective, increase to seven pills. For children, two pills the size of yellow millet.
Quan Sheng Zhi Mi Banshu Wan (Pinellia-Sulfur Pill):
Banxia (Pinellia Tuber, three liang, washed seven times in boiling water), Liuhuang (Sulfur, two liang, ground and floated).
Grind into powder. Use ginger juice and wheat paste to form pills the size of paulownia seeds. Take thirty pills per dose, washed down with rice drink, at any time. For children, three to five pills the size of millet grains.