芍药 桔梗（炒） 吴蓝 山栀子仁〔各半分（一）〕 枇杷叶（三分拭去毛姜汁炙） 上
粗捣筛。
每
清凉散（出圣济总录）治阳毒伤寒。口干烦躁。大渴。发汗。
葛根（锉二两） 大黄（锉炒） 黄芩（去黑心） 朴硝 麻黄（去根节） 甘草（炙
锉各一两）
桂（去粗皮三分） 上捣罗为散。每服二钱匕。新汲水调下。
琥珀丸（出圣济总录）治阳毒伤寒。六七日间。服热药过度。致使阳气内伏。
身体微热。眼
琥珀（研一分） 黄连（去须） 黄柏（去粗皮） 大黄（煨锉各半两） 巴豆（去皮
心膜出油
取霜二钱） 上捣罗四味为细末。与巴豆霜拌匀。煮薄面糊和丸。如绿豆大。每服一（十）
丸。
柳枝
妙应汤（出圣济总录）治阳毒伤寒。遍身壮热。大喘上气。躁闷。
甘草（炙锉） 人参 赤茯苓（去黑皮各一两） 大黄（煨锉） 山栀子（去皮） 麻
黄（去根
节各半两） 陈橘皮（去白炒） 木香（各一分） 上粗捣筛。每服三钱匕。水一盏。入蜜
一匙。
生
铁粉散（出圣济总录）治阳毒伤寒。发狂走者。
铁粉 朴硝（各一两） 天竺黄（半两） 龙脑（一分） 右四味。研令匀细。每服二
钱匕。
鸡清水调下。不拘时。
水渍法（出活人书）治阳毒壮盛。内外结热。烦躁。
以新汲水。渍叠布数重。搭于胸上。须臾蒸热。再浸再搭。数换新水浸之。此良法也。
治阳毒伤寒。壮热头痛。心神烦躁。利胸膈。（出肘后方）
用生瓜菜。捣取自然汁。饮之。叶生捣。贴肿毒。
升麻汤 治伤寒一二日。便成阳毒。或服药吐下之后。变成阳毒。身重。腰背疼
痛。烦闷不安。狂言。或走。或见鬼神。或吐血下利。其脉浮大数。面赤斑斑如锦纹。
咽喉痛。唾脓血。五日可疗。至七日不可疗也。宜服升麻汤。肘后。阳毒升麻汤。治证
同。无栀子、鳖甲。
升麻（二分） 当归（二分） 蜀椒（出汗一分） 雄黄（研） 栀子 桂心（各一分）
甘草
〔三（二）分炙〕 鳖甲（大如手一片炙） 上件药切。以水五升。煮取二升半。分三服。
如人
行五里久。再服。温覆手足。毒出则汗。汗出则解。不解。重作服。亦取得吐。佳。阴毒去
雄黄。忌海藻、菘菜、生葱、苋菜。张仲景方。无栀子、桂心。阴毒去雄黄、蜀椒。
治阳毒伤寒。昏愦不知。药食隔断者。（出经验良方）
将早晚白米。用新汲水烂研作浆。频频灌之。能解诸毒。续谷气。
阳毒栀子汤（一名栀子仁汤出济生拔粹方）治阳毒伤寒。壮热。百节疼痛。
升麻 栀子仁 黄芩 芍药 石膏 知母 甘草 杏仁 柴胡（各等分） 上为粗末。
每
服五钱。生姜五片。豉百粒。水煎服。一方有大青。
治阳毒伤寒。面赤头痛。身上热如火。心神躁。眼赤睛迸露。头目昏眩。项背强
直。坐卧不
麻黄（去根） 杏仁（去尖） 山栀 黄芩 柴胡 前胡（各去毛） 大黄 白术 桔
梗通
草羌活 秦艽 干葛 牡丹皮（去心） 荆芥穗（各一分） 牵牛（一两） 半夏（四铢）
黄连
细辛（各三钱） 上捣罗为末。每服五钱匕。水一碗。生姜三片。葱三枝。同煎一两沸。食
后
热服。
浴肠汤 治阳厥发狂。将成疸。
大黄（四两湿纸裹） 大青（一两） 栀子（一两） 甘草（一两炙） 上水五升。煎
至二升。
纳朴硝五合。再熬去一升。分四服。量虚实与之。
治阳毒入胃。下血频。疼痛不可忍。
用郁金五个。大者。牛黄一皂荚子大。别细研二味。同为散。每服用醋浆一盏。同煎三
沸。温服。
【背景信息】
书名：普济方 作者：朱梓 朝代：明·永乐四年 章节：阳毒（附论）(2/2) 类别：方剂
芍药、桔梗（炒）、吴蓝、山栀子仁（各半分[注1]）。枇杷叶（三分，拭去毛，用姜汁炙）。以上药材粗捣筛过。
每服清凉散（出自《圣济总录》），治疗阳毒伤寒。症状包括口干烦躁、大渴。治法为发汗。
葛根（锉碎二两）、大黄（锉碎并炒）、黄芩（去掉黑心部分）、朴硝、麻黄（去掉根和节）、甘草（炙后锉碎，各一两）、桂（去掉粗皮，三分）。以上药材捣碎过罗制成散剂。每次服用二钱匕，用新汲水调服。
琥珀丸（出自《圣济总录》），治疗阳毒伤寒。在发病六七日间，因服用热性药物过度，致使阳气内伏。症状表现为身体微热、眼睛...（原文此处似有缺漏，依文意推测可能涉及眼部症状或神志异常，但严格按原文翻译）
琥珀（研细一分）、黄连（去掉须）、黄柏（去掉粗皮）、大黄（煨后锉碎，各半两）、巴豆（去皮、心膜，出油取霜二钱）。以上将前四味捣碎过罗成细末，与巴豆霜拌匀，煮薄面糊和丸，如绿豆大小。每次服用一（十）丸。柳枝...（原文此处“柳枝”二字孤立，疑为排版错误或残留字，暂按原文列出）
妙应汤（出自《圣济总录》），治疗阳毒伤寒。症状为遍身壮热、大喘上气、躁闷。
甘草（炙后锉碎）、人参、赤茯苓（去掉黑皮，各一两）、大黄（煨后锉碎）、山栀子（去掉皮）、麻黄（去掉根节，各半两）、陈橘皮（去掉白瓤并炒）、木香（各一分）。以上药材粗捣筛过。每次服用三钱匕，用水一盏，加入蜂蜜一匙，煎至...（原文“生”字疑似误植或截断，结合语境应为煎煮过程，此处仅译原文可见部分）
铁粉散（出自《圣济总录》），治疗阳毒伤寒。症状为发狂奔走者。
铁粉、朴硝（各一两）、天竺黄（半两）、龙脑（一分）。右四味药材，研令均匀细碎。每次服用二钱匕，用鸡清水调服，不拘时间。
水渍法（出自《活人书》），治疗阳毒壮盛。症状为内外结热、烦躁。
用新汲水，浸湿叠数重的布，搭在胸上。不久布变热，再浸水再搭。多次更换新水浸泡。这是良法。
治疗阳毒伤寒。症状为壮热头痛、心神烦躁、利胸膈。（出自《肘后方》）
用生瓜菜，捣取自然汁，饮用。叶子生捣，贴敷肿毒。
升麻汤，治疗伤寒一二日，便成为阳毒。或者服药吐下之后，变成阳毒。症状为身重、腰背疼痛、烦闷不安、狂言、或奔走、或见鬼神、或吐血下利。脉象浮大数。面色红赤，斑斑如锦纹。咽喉痛，唾脓血。五日可治疗，至七日不可治疗。宜服用升麻汤。《肘后备急方》中的阳毒升麻汤，主治证候相同，只是没有栀子、鳖甲。
升麻（二分）、当归（二分）、蜀椒（出汗一分）、雄黄（研细）、栀子、桂心（各一分）、甘草〔三（二）分炙〕、鳖甲（大如手一片，炙）。以上药材切碎，用水五升，煮取二升半，分三次服用。如果人行走五里路的久暂时间，再服用。温覆手足，毒邪外出则出汗，汗出则病解。若不解，重新制作服用，也能取得呕吐的效果，较好。阴毒去掉雄黄。忌食海藻、菘菜、生葱、苋菜。张仲景方，没有栀子、桂心。阴毒去掉雄黄、蜀椒。
治疗阳毒伤寒。症状为昏愦不知、药食隔断者。（出自《经验良方》）
将早晚的白米，用新汲水烂研作浆，频频灌之。能解诸毒，续谷气。
阳毒栀子汤（一名栀子仁汤，出自《济生拔粹方》），治疗阳毒伤寒。症状为壮热、百节疼痛。
升麻、栀子仁、黄芩、芍药、石膏、知母、甘草、杏仁、柴胡（各等分）。以上制成粗末。每次服用五钱，生姜五片，豉百粒，水煎服。另一版本有大青。
治疗阳毒伤寒。症状为面赤头痛、身上热如火、心神躁、眼赤睛迸露、头目昏眩、项背强直、坐卧不...（原文截断）
麻黄（去掉根）、杏仁（去掉尖）、山栀、黄芩、柴胡、前胡（各去毛）、大黄、白术、桔梗通草羌活秦艽干葛牡丹皮（去心）、荆芥穗（各一分）、牵牛（一两）、半夏（四铢）、黄连细辛（各三钱）。以上捣碎过罗成末。每次服用五钱匕，用水一碗，生姜三片，葱三枝，同煎一两沸。食后热服。
浴肠汤，治疗阳厥发狂。将成疸。
大黄（四两，湿纸裹）、大青（一两）、栀子（一两）、甘草（一两，炙）。以上用水五升，煎至二升。纳朴硝五合，再熬去一升，分四次服用。根据虚实给予剂量。
治疗阳毒入胃。症状为下血频繁、疼痛不可忍。
用郁金五个，大的。牛黄一皂荚子大。分别细研这两味药，同为散剂。每次服用用醋浆一盏，同煎三沸，温服。
Background Information:
Book: Pu Ji Fang (General Manual of Prescriptions); Author: Zhu Zi; Dynasty: Ming, Yongle 4th Year; Chapter: Yang Du (With Discussion) (2/2); Category: Formulas
Shao Yao (Radix Paeoniae Rubra), Jie Geng (Radix Platycodonis) (stir-fried), Wu Lan (Indigo Naturalis), Shan Zhi Zi Ren (Semen Gardeniae) [each 0.5 fen]. Pi Pa Ye (Folium Eriobotryae) (3 fen, wipe off hairs, stir-fry with ginger juice). The above herbs are coarsely pounded and sieved.
Qing Liang San (Cooling Powder) (from Sheng Ji Zong Lu): Treats Yang Du Shang Han (Yang Toxicity Cold Damage). Symptoms include dry mouth, irritability, and extreme thirst. Therapeutic method is to induce sweating.
Ge Gen (Radix Puerariae) (cut into pieces, 2 liang), Da Huang (Radix et Rhizoma Rhei) (cut into pieces and stir-fried), Huang Qin (Radix Scutellariae) (remove black heart), Po Xiao (Natrii Sulfas), Ma Huang (Herba Ephedrae) (remove roots and joints), Gan Cao (Radix Glycyrrhizae) (roasted and cut into pieces, each 1 liang), Gui (Cortex Cinnamomi) (remove coarse bark, 3 fen). The above herbs are pounded, sifted, and made into a powder. Take 2 qian bi (approx. 6g) per dose, mixed with fresh cold water.
Hu Po Wan (Amber Pill) (from Sheng Ji Zong Lu): Treats Yang Du Shang Han. Occurring between the 6th and 7th day, caused by excessive intake of hot-natured medicines, leading to internal entrapment of Yang Qi. Symptoms include slight body heat and eye [text incomplete in source].
Hu Po (Succinum) (ground, 1 fen), Huang Lian (Rhizoma Coptidis) (remove threads), Huang Bo (Cortex Phellodendri) (remove coarse bark), Da Huang (Radix et Rhizoma Rhei) (baked and cut into pieces, each 0.5 liang), Ba Dou (Fructus Crotonis) (remove skin, heart membrane, express oil to obtain resin, 2 qian). The above four herbs are pounded and sifted into fine powder, mixed evenly with Ba Dou Frost, and bound with thin wheat paste to form pills the size of mung beans. Take 1 (or 10) pills per dose. Liu Zhi (Willow Branch) [isolated term in source].
Miao Ying Tang (Miraculous Response Decoction) (from Sheng Ji Zong Lu): Treats Yang Du Shang Han. Symptoms include intense fever all over the body, severe panting with upward rushing of Qi, restlessness, and oppression.
Gan Cao (Radix Glycyrrhizae) (roasted and cut into pieces), Ren Shen (Radix Ginseng), Chi Fu Ling (Poria with Red Host) (remove black skin, each 1 liang), Da Huang (Radix et Rhizoma Rhei) (baked and cut into pieces), Shan Zhi Zi (Fructus Gardeniae) (remove skin), Ma Huang (Herba Ephedrae) (remove roots and joints, each 0.5 liang), Chen Ju Pi (Pericarpium Citri Reticulatae) (remove white pith and stir-fry), Mu Xiang (Radix Aucklandiae) (each 1 fen). The above herbs are coarsely pounded and sieved. Take 3 qian bi per dose, with one cup of water and one spoonful of honey, decocted [source text ends abruptly with "Sheng"].
Tie Fen San (Iron Powder Powder) (from Sheng Ji Zong Lu): Treats Yang Du Shang Han. Symptoms include madness and running about.
Tie Fen (Ferrum Oxydatum Rubrum), Po Xiao (Natrii Sulfas) (each 1 liang), Tian Zhu Huang (Calculus Bovis), Long Nao (Borneolum Syntheticum) (each 0.5 liang and 1 fen respectively). The right four ingredients are ground until uniform and fine. Take 2 qian bi per dose, mixed with chicken clear water. Take at any time without restriction.
Shui Zi Fa (Water Soaking Method) (from Huo Ren Shu): Treats vigorous Yang Du. Symptoms include internal and external accumulated heat, irritability.
Use fresh cold water to soak several layers of cloth, place it on the chest. After a short while, when it becomes hot, re-soak and re-place. Repeat changing to new water multiple times. This is an excellent method.
Treats Yang Du Shang Han. Symptoms include intense fever, headache, mental irritability, and clearing of the chest and diaphragm. (from Zhou Hou Bei Ji Fang)
Use raw Gua Cai (vegetable melon), pound to extract natural juice, and drink it. Leaves pounded raw can be applied externally to swellings and sores.
Sheng Ma Tang ( Cimicifugae Decoction): Treats Shang Han (Cold Damage) that becomes Yang Du within one or two days. Or transforms into Yang Du after vomiting or purging treatment. Symptoms include heavy body, pain in waist and back, restlessness and unease, delirious speech, running about, seeing ghosts or spirits, hematemesis, or diarrhea. Pulse is floating, large, and rapid. Face is red with spots like brocade patterns. Sore throat, spitting of pus and blood. Treatable within five days; untreatable after seven days. Should take Sheng Ma Tang. Yang Du Sheng Ma Tang from Zhou Hou Bei Ji Fang has the same indications but lacks Zhi Zi and Bie Jia.
Sheng Ma (Rhizoma Cimicifugae) (2 fen), Dang Gui (Radix Angelicae Sinensis) (2 fen), Shu Jiao (Fructus Zanthoxyli) (sweat out moisture, 1 fen), Xiong Huang (Realgar) (ground), Zhi Zi (Fructus Gardeniae), Gui Xin (Cortex Cinnamomi) (each 1 fen), Gan Cao (Radix Glycyrrhizae) [3 (or 2) fen roasted], Bie Jia (Carapax et Plastrum Testudinis) (one piece as large as a hand, roasted). The above herbs are cut. Decoct in five sheng of water to obtain two and a half sheng. Divide into three doses. If a person walks for the duration of five li, take the next dose. Cover hands and feet warmly. When toxins exit, sweat will occur, and the disease resolves upon sweating. If not resolved, prepare and take again; inducing vomiting is also effective and desirable. For Yin Du (Yin Toxicity), remove Xiong Huang. Avoid Hai Zao (Sargassum), Song Cai (Chinese Cabbage), raw Cong (Scallion), and Xian Cai (Amaranth). Zhang Zhongjing's formula lacks Zhi Zi and Gui Xin. For Yin Du, remove Xiong Huang and Shu Jiao.
Treats Yang Du Shang Han. Symptoms include coma/confusion, inability to take medicine or food. (from Jing Yan Liang Fang)
Take morning and evening white rice, grind thoroughly with fresh cold water to make a slurry, and administer frequently. It can resolve various toxins and replenish Gu Qi (Grain Qi).
Yang Du Zhi Zi Tang (Yang Toxicity Gardenia Decoction) (also known as Zhi Zi Ren Tang, from Ji Sheng Ba Cui Fang): Treats Yang Du Shang Han. Symptoms include intense fever and pain in all joints.
Sheng Ma (Rhizoma Cimicifugae), Zhi Zi Ren (Semen Gardeniae), Huang Qin (Radix Scutellariae), Shao Yao (Radix Paeoniae Rubra), Shi Gao (Gypsum Fibrosum), Zhi Mu (Rhizoma Anemarrhenae), Gan Cao (Radix Glycyrrhizae), Xing Ren (Semen Armeniacae Amarum), Chai Hu (Radix Bupleuri) (each equal parts). Make into coarse powder. Take 5 qian per dose, with 5 slices of Sheng Jiang (Rhizoma Zingiberis Recens) and 100 grains of Chi Dou (Semen Glycines Preparatum), decoct in water. Another version includes Da Qing (Folium Isatidis).
Treats Yang Du Shang Han. Symptoms include red face and headache, body heat like fire, mental restlessness, red eyes with bulging eyeballs, dizziness of head and eyes, stiffness of neck and back, inability to sit or lie down [text incomplete in source].
Ma Huang (Herba Ephedrae) (remove roots), Xing Ren (Semen Armeniacae Amarum) (remove tips), Shan Zhi Zi (Fructus Gardeniae), Huang Qin (Radix Scutellariae), Chai Hu (Radix Bupleuri), Qian Hu (Radix Peucedani) (each remove hairs), Da Huang (Radix et Rhizoma Rhei), Bai Zhu (Rhizoma Atractylodis Macrocephalae), Jie Geng (Radix Platycodonis), Tong Cao (Medulla Tetrapanacis), Qiang Huo (Rhizoma Notopterygii), Qin Jiao (Radix Gentianae Macrophyllae), Gan Ge (Radix Puerariae), Mu Dan Pi (Cortex Moutan) (remove heart), Jing Jie Sui (Spica Schizonepetae) (each 1 fen), Qian Niu (Semen Pharbitidis) (1 liang), Ban Xia (Rhizoma Pinelliae) (4 zhu), Huang Lian (Rhizoma Coptidis), Xi Xin (Herba Asari) (each 3 qian). The above are pounded and sifted into powder. Take 5 qian bi per dose, with one bowl of water, 3 slices of Sheng Jiang, and 3 stems of Cong Bai (Bulbus Allii Cepae), decoct together for one boil. Take warm after meals.
Yu Chang Tang (Intestinal Bathing Decoction): Treats Yang Jue (Yang Reversal) with madness. Approaching Jaundice.
Da Huang (Radix et Rhizoma Rhei) (4 liang, wrapped in wet paper), Da Qing (Folium Isatidis) (1 liang), Zhi Zi (Fructus Gardeniae) (1 liang), Gan Cao (Radix Glycyrrhizae) (1 liang, roasted). Decoct in five sheng of water to two sheng. Add Po Xiao (Natrii Sulfas) 5 he, boil further to reduce by one sheng. Divide into four doses. Administer according to deficiency or excess.
Treats Yang Du entering the Stomach. Symptoms include frequent bloody stool and unbearable pain.
Use Yu Jin (Radix Curcumae) five pieces, large ones. Niu Huang (Calculus Bovis) the size of a soap pod. Grind these two separately into fine powder, then mix as a powder. For each dose, use one cup of vinegar grain water, decoct together for three boils, and take warm.