丹溪曰∶梦遗精滑，专主乎热，热则流通，宜滋阴降火。劳神思者，安神养心。久而虚
脱者，须兼补药及收涩之药，无有不愈。
薛立斋曰∶按前证若肾气不足，用益志汤、金锁正元丹；肝肾虚热者，用六味丸、加味
逍遥散；脾虚热者，用六味丸、补中益气汤。凡此悉属不足之证，宜用十全大补汤，或用萆
厘清饮送八味丸。又曰∶按前证属足三阴亏损所致。若肝肾虚热者，用四物加柴胡、山栀
、山茱萸、山药。脾胃气虚者，用补中益气加山茱萸、山药。思虑伤脾者，兼用归脾汤加山
茱萸、山药。肝肾亏损者，六味丸。真阳虚败者，八味丸。心肾不交，用萆 厘清饮。心气
虚热者，清心莲子饮。
楼全善《纲目》云∶一壮年梦遗白浊，与涩精药益甚，知其郁滞，改用导赤散，大剂服
之，遗浊皆止。又一中年梦遗，与涩药勿效，改与神芎丸下之，下后与猪苓丸，遂愈。
徐东皋云∶梦遗因心经有火，神思不宁，所以梦与人交而精泄，治当用清心、安神、温
胆等剂，加黄连、生地、人参、远志、茯神、枣仁、羚羊角之类。有自遗者，乃气血虚而下
脱，有因热而流通者，当分虚实，须用八物汤加龙骨、牡蛎、樗根皮之类。有小便后精出不
可禁者，或不小便而自出者，或茎中出而痒痛，常如欲小便者，并宜先服辰砂妙香散，或威
喜丸，或厘清饮，别以绵裹龙骨同煎，或加五倍子、牡蛎、白茯苓、五味子之属煎服。
王宇泰曰∶凡病精泄不禁，自汗头眩，虚极，或寒或热，用补涩之药不效，其脉浮软而
散，盖非虚也，亦非房室过度，此无他，心有所睹，因有所慕，意有所乐，欲想方兴，不遂
所欲，而致斯疾，既以药补且固，不效，将何以治之？缘心有爱则神不归，意有想则志不宁
，当先和营卫，营卫和则心安。次调其脾，脾气和则志舍定。心肾交媾，精神内守，其病自
愈。其法用人参三钱，当归一钱，洗焙为末，作三服，糯米饮调下，服毕自汗出而寒热退。
若头眩未除，用川芎三钱，人参一钱，焙为末，作三服，沸汤调下。头眩瘥而精不禁者，用
芍药半两，丁香三钱，木香三钱，锉散，每服用生姜五片，枣二枚，以水同煎，空心
服。即心安神定，精固神悦。
朱丹溪说：梦遗和滑精，主要归因于热证。热邪会导致精气流通失控，治疗应当滋阴并降火。对于因过度劳神思虑导致者，应安神养心。若病程长久导致虚脱，必须配合使用补益药及收敛固涩的药物，没有不治愈的。
薛立斋说：按照上述病症，如果是肾气不足，使用益志汤、金锁正元丹；如果是肝肾虚热，使用六味丸、加味逍遥散；如果是脾虚有热，使用六味丸、补中益气汤。凡此种种都属于虚损不足的证候，适宜使用十全大补汤，或者用萆厘清饮送服八味丸。他又说：按照上述病症，属于足三阴经亏损所致。若是肝肾虚热，使用四物汤加入柴胡、山栀、山茱萸、山药。若是脾胃气虚，使用补中益气汤加入山茱萸、山药。若是思虑损伤脾气，兼用归脾汤加入山茱萸、山药。若是肝肾亏损，使用六味丸。若是真阳虚败，使用八味丸。若是心肾不交，使用萆厘清饮。若是心气虚热，使用清心莲子饮。
楼全善在《本草纲目》中记载：有一位壮年男子出现梦遗和白浊，服用涩精药物后病情反而加重，判断其为郁滞之证，改用导赤散，大剂量服用，遗精和白浊都停止了。又有一位中年男子梦遗，服用涩精药物无效，改用神芎丸攻下，泻下后再服用猪苓丸，于是痊愈。
徐东皋说：梦遗是因为心经有火，神志思虑不安，所以在梦中与人交合而精液外泄，治疗应当使用清心、安神、温胆等方剂，加入黄连、生地、人参、远志、茯神、枣仁、羚羊角等药物。有自行遗精者，是气血虚弱而下脱；有因热邪导致流通失控者，应当分辨虚实，需要使用八物汤加入龙骨、牡蛎、樗根皮等药物。有小便之后精液流出不可控制者，或者不排尿而自行流出者，或者尿道口流出且伴有痒痛，经常感觉想小便的，都适宜先服用辰砂妙香散，或威喜丸，或厘清饮，另外用绵布包裹龙骨同煎，或者加入五倍子、牡蛎、白茯苓、五味子等药材煎服。
王宇泰说：凡是患有精液泄漏无法控制，伴随自汗、头晕目眩，极度虚弱，或怕冷或发热，使用补益和固涩药物无效，脉象浮软而散的，这并非单纯的虚证，也不是房事过度所致。这没有其他原因，是因为心中有所目睹，因而有所爱慕，意念有所喜好，欲望刚刚兴起，却未能满足欲望，从而导致这种疾病。既然用药补益且固涩无效，又将如何治疗呢？原因是心中有所爱则神不归位，意念有所想则志不宁静，应当先调和营卫，营卫调和则心安。其次调理脾胃，脾气调和则志舍安定。心肾相交媾，精神内守，病自然痊愈。其方法是用三钱人参，一钱当归，洗净焙干研为细末，分为三次服用，用糯米饮调服，服完后自然会出汗，寒热症状消退。如果头晕目眩未消除，使用三钱川芎，一钱人参，焙干研为细末，分为三次服用，用沸水调服。头晕目眩痊愈但精液仍不禁者，使用半两芍药，三钱丁香，三钱木香，锉成散剂，每次服用时加生姜五片，大枣二枚，与水同煎，空腹服用。这样就能使心安神定，精液固摄，神气愉悦。
Zhu Danxi stated: Nocturnal emission and spermatorrhea are primarily attributed to Heat. Heat causes the uncontrolled flow of essence; treatment should focus on nourishing Yin and descending Fire. For cases caused by excessive mental labor and overthinking, one should calm the Spirit and nourish the Heart. If the condition persists for a long time leading to deficiency collapse, tonifying herbs combined with astringent herbs must be used, and there is no case that will not heal.
Xue Lizhai stated: Regarding the aforementioned conditions, if Kidney Qi is insufficient, Yizhi Tang (Yi Zhi Decoction) or Jin suo Zheng yuan Dan (Golden Lock Correcting Origin Pill) should be used; if there is Deficient-Heat in the Liver and Kidneys, Liuwei Wan (Six-Ingredient Pill with Rehmannia) or Jiawei Xiaoyao San (Modified Free and Easy Wanderer Powder) should be used; if there is Spleen deficiency with Heat, Liuwei Wan or Buzhong Yiqi Tang (Tonify the Middle and Augment the Qi Decoction) should be used. All these belong to deficiency syndromes suitable for Shiquan Dabu Tang (Ten Complete Great Tonifying Decoction), or using Bilixi Qingyin (Bilixi Clearing Drink) to deliver Bawei Wan (Eight-Ingredient Pill). He further stated: Regarding the aforementioned conditions, they result from the depletion of the three Yin meridians of the foot. If there is Deficient-Heat in the Liver and Kidneys, Siwu Tang (Four Substance Decoction) added with Chai Hu (Bupleuri Radix), Shan Zhi (Gardeniae Fructus), Shan Zhu Yu (Corni Fructus), and Shan Yao (Dioscoreae Rhizoma) should be used. If there is Spleen and Stomach Qi deficiency, Buzhong Yiqi Tang added with Shan Zhu Yu and Shan Yao should be used. If overthinking damages the Spleen Qi, Guipi Tang (Restore the Spleen Decoction) added with Shan Zhu Yu and Shan Yao should be used concurrently. If there is Liver and Kidney depletion, Liuwei Wan should be used. If True Yang is deficient and failing, Bawei Wan should be used. If Heart and Kidney fail to interact, Bilixi Qingyin should be used. If there is Heart Qi deficiency with Heat, Qingxin Lianzi Yin (Clear Heart Lotus Seed Drink) should be used.
Lou Quanshan recorded in Bencao Gangmu (Compendium of Materia Medica): A young man suffered from nocturnal emission and white turbidity; after taking astringent herbs for essence retention, his condition worsened. Recognizing it as stagnation, he switched to Daochi San (Guide Out Redness Powder), administered in large doses, which stopped both emission and turbidity. Another middle-aged man suffered from nocturnal emission; astringent herbs were ineffective. He was treated with Shenxiong Wan (Shenxiong Pill) to purge, followed by Zhuling Wan (Polyporus Pill) after purgation, resulting in recovery.
Xu Donggao stated: Nocturnal emission occurs due to Fire in the Heart meridian and unsettled Spirit/thoughts, causing ejaculation during dreams of sexual intercourse. Treatment should employ formulas that clear the Heart, calm the Spirit, and warm the Gallbladder, adding Huang Lian (Coptidis Rhizoma), Sheng Di (Rehmanniae Radix), Ren Shen (Ginseng Radix et Rhizoma), Yuan Zhi (Polygalae Radix), Fu Shen (Poria with Hostwood), Suan Zao Ren (Ziziphi Spinosae Semen), Ling Yang Jiao (Antelopi Cornu), and similar herbs. For spontaneous emission, this is due to Qi and Blood deficiency leading to downward collapse; for those caused by Heat leading to uncontrolled flow, one must differentiate between deficiency and excess, using Bawu Tang (Eight Substance Decoction) added with Long Gu (Fossilia Ossis Mastodi) and Mu Li (Ostreae Concha), Chu Gen Pi (Stemonae Rhizomatis Cortex), and similar herbs. For cases where essence flows uncontrollably after urination, or flows spontaneously without urination, or flows from the urethra accompanied by itching and pain with a constant sensation of needing to urinate, one should first take Chensha Miaoxiang San (Cinnabar Wonderful Fragrance Powder), or Weixi Wan (Weixi Pill), or Liqing Yin (Liqing Drink). Additionally, Long Gu wrapped in cotton should be decocted together, or Wubeizi (Galla Chinensis), Mu Li, Bai Fu Ling (Poria), and Wu Wei Zi (Schisandrae Fructus) may be added to the decoction for administration.
Wang Yutai stated: In cases of uncontrolled seminal leakage accompanied by spontaneous sweating, dizziness, extreme weakness, alternating chills and fever, where tonifying and astringent herbs are ineffective, and the pulse is floating, soft, and scattered, this is not merely a deficiency syndrome, nor is it caused by excessive sexual activity. The cause lies in the mind having witnessed something, thereby developing affection; the intent has desires, and when arousal arises but remains unsatisfied, this disease results. Since medicinal tonification and consolidation have failed, how else can it be treated? The reason is that when the Heart loves, the Spirit does not return; when the Intent thinks, the Will is not peaceful. One must first harmonize Ying and Wei (Nutritive and Defensive levels); when Ying and Wei are harmonized, the Heart becomes calm. Next, regulate the Spleen; when Spleen Qi is harmonized, the residence of the Will stabilizes. When Heart and Kidney interact and Essence and Spirit remain within, the disease heals naturally. The method involves using 3 qian of Ren Shen, 1 qian of Dang Gui, cleaned and dried, ground into powder, divided into three doses, taken with Rice Decoction (Nuomi Yin). After completion, sweating will occur naturally, and chills and fever will subside. If dizziness persists, use 3 qian of Chuan Xiong (Chuanxiong Rhizoma) and 1 qian of Ren Shen, dried and ground into powder, divided into three doses, taken with boiling water. If dizziness resolves but seminal control remains poor, use 0.5 liang of Shao Yao (Paeoniae Radix Alba), 3 qian of Ding Xiang (Caryophylli Flos), and 3 qian of Mu Xiang (Aucklandiae Radix), crushed into a powder. Each dose should be decocted with five slices of Sheng Jiang (Zingiberis Rhizoma Recens) and two dates (Da Zao), taken on an empty stomach. This will calm the Heart, stabilize the Spirit, secure the essence, and bring joy to the Shen.