（宋《开宝》）
【释名】留求子。
志曰∶俗传潘州郭使君疗小儿多是独用此物，后医家因号为使君子也。
时珍曰∶按嵇含《南方草木状》谓之留求子，疗婴孺之疾。则自魏、晋已用，但名异耳。
【集解】志曰∶生交、广等州。形如栀子，棱瓣深而两头尖，似诃黎勒而轻。
颂曰∶今岭南州郡皆有之，生山野中及水岸。其茎作藤，如手指大。其叶青，如两指头，
长二寸。三月生花淡红色，久乃深红，有五瓣。七、八月结子如拇指大，长一寸许，大类栀
子而有五棱，其壳青黑色，内有仁白色，七月采之。
宗 曰∶其仁味如椰子。医家亦兼用壳。
时珍曰∶原出海南、交趾。今闽之邵武，蜀之眉州，皆栽种之，亦易生。其藤如葛，绕
树而上。叶青如五加叶。五月开花，一簇一、二十葩，红色轻盈如海棠。其实长
合成，有棱。先时半黄，老则紫黑。其中仁长如榧仁，色味如栗。久则油黑，不可用。
【气味】甘，温，无毒。
【主治】小儿五疳，小便白浊，杀虫，疗泻痢（《开宝》）。
病疮癣（时珍）。
【发明】时珍曰∶凡杀虫药多是苦辛，惟使君子、榧子甘而杀虫，亦异也。凡大人小儿
有虫病，但每月上旬侵晨空腹食使君子仁数枚，或以壳煎汤咽下，次日
七生七煨食亦良。忌饮热茶，犯之即泻。此物味甘气温，既能杀虫，又益脾胃，所以能敛虚
热而止泻痢，为小儿诸病要药。俗医乃谓杀虫至尽，无以消食，鄙俚之言也。树有蠹，屋有
蚁，国有盗，福耶祸耶？修养者先去三尸，可类推矣。
【附方】新六。
小儿脾疳∶使君子、芦荟等分，为末。米饮每服一钱。（《儒门事亲》）
肌瘦面黄，渐成疳疾∶使君子仁三钱，木鳖子仁五钱，为末，水丸龙眼大。每以一丸，用鸡
子一个破顶，入药在内，饭上蒸熟，空心食之。（杨起《简便单方》）
小儿蛔痛，口流涎沫∶使君子仁为末，米饮五更调服一钱。（《全幼心鉴》）
小儿虚肿，头面阴囊俱浮∶用使君子一两，去壳，蜜五钱炙尽，为末。每食后米汤服一
钱。（《简便方》）
鼻渣面疮∶使君子仁，以香油少许，浸三、五个。临卧时细嚼，香油送下，久
（《普济方》）
虫牙疼痛∶使君子煎汤频漱。（《集简方》）
（引自宋代《开宝本草》）
【释名】别名留求子。
苏颂记载：民间传说潘州的郭使君治疗小儿疾病多单独使用此物，后来的医家因此称它为“使君子”。
李时珍说：查阅嵇含的《南方草木状》，称之为留求子，用于治疗婴幼儿的疾病。这说明从魏、晋时期就已经开始使用，只是名称不同罢了。
【集解】苏颂记载：产于交州、广州等州。形状像栀子，棱瓣深且两头尖，比诃黎勒轻。
苏颂又说：现在岭南各州郡都有生长，生于山野中及水岸边。它的茎是藤本，有手指粗。叶子青色，像两个指头宽，长二寸。三月开出淡红色的花，时间久了变成深红色，有五片花瓣。七、八月结出果实，大小如拇指，长约一寸左右，大体像栀子但有五个棱，外壳青黑色，里面有白色的种仁，七月采收。
陈承说：它的种仁味道像椰子。医家也兼用其壳。
李时珍说：原产于海南、交趾。现在福建邵武、四川眉州等地都有栽种，也容易生长。它的藤蔓像葛藤，缠绕树木向上生长。叶子青色，像五加叶。五月开花，一簇有一二十朵花，红色轻盈像海棠花。果实长形，有棱。起初半黄，老了变成紫黑色。里面的种仁长像榧子仁，颜色和味道像栗子。放久了会变黑油亮，就不能使用了。
【气味】味甘，性温，无毒。
【主治】小儿五疳，小便白浊，杀虫，治疗泻痢（出自《开宝本草》）。
治疗疮癣（李时珍补充）。
【发明】李时珍说：凡是杀虫药大多味苦辛，只有使君子、榧子味甘而能杀虫，这也是独特的地方。凡是大人小孩有寄生虫病，只要每月上旬清晨空腹吃几枚使君子仁，或者用壳煎汤喝下去，第二天早上生吃或煨熟吃也很好。忌喝热茶，否则就会腹泻。此物味甘气温，既能杀虫，又能补益脾胃，所以能收敛虚热并止住泻痢，是治疗小儿各种疾病的要药。庸俗的医生却说它杀虫太尽，导致无法消化食物，这是粗鄙浅陋的说法。树里有蛀虫，屋里有蚂蚁，国家里有盗贼，这是福还是祸呢？修道养生的人先除去三尸虫，道理可以类推了。
【附方】新收录六首。
小儿脾疳：使君子、芦荟各等分，研成粉末。每次用米汤送服一钱。（出自《儒门事亲》）
身体消瘦面色发黄，逐渐形成疳疾：使君子仁三钱，木鳖子仁五钱，研成粉末，用水做成梧桐子大的水丸。每次取一丸，用一个鸡蛋打破顶部，将药放入蛋内，在饭上蒸熟，空腹食用。（出自杨起《简便单方》）
小儿蛔虫疼痛，口流涎沫：使君子仁研成粉末，五更时用米汤调服一钱。（出自《全幼心鉴》）
小儿虚肿，头面阴囊都浮肿：使用使君子一两，去掉壳，用五钱蜂蜜炙烤至干，研成粉末。每次饭后用米汤送服一钱。（出自《简便方》）
鼻部赘生物和面部疮疡：使君子仁，用少许香油浸泡三到五个。临睡前细细咀嚼，用香油送下，长期服用有效。（出自《普济方》）
虫牙疼痛：用使君子煎汤频繁漱口。（出自《集简方》）
(Sourced from the Song Dynasty *Kaibao Bencao*)
[Names] Also known as Liuqiu Zi.
Su Song recorded: Folk legends state that Guo Shijun (Official Guo) of Panzhou often treated pediatric diseases using this herb exclusively, leading later physicians to name it "Shijunzi" (Quisqualis Fruit).
Li Shizhen stated: According to Ji Han's *Nanfang Caomuzhuang* (Records of Plants in the Southern Regions), it is called Liuqiu Zi and used to treat infant ailments. This indicates its use dates back to the Wei and Jin dynasties, differing only in nomenclature.
[Collection and Explanation] Su Song recorded: It grows in Jiaozhou, Guangzhou, and other prefectures. Its shape resembles Gardenia jasminoides fruit (Zhizi), with deep lobes and pointed ends, lighter than Chebula terminalia fruit (Helile).
Su Song further noted: It is now found in all prefectures of Lingnan, growing in mountains, wild areas, and along waterbanks. The stem is a vine, about the thickness of a finger. The leaves are green, two fingers wide, and two cun long. In the third lunar month, it produces pale red flowers that deepen to dark red over time, featuring five petals. Fruits appear in the seventh and eighth lunar months, thumb-sized and about one cun long, resembling Zhizi but with five ridges. The shell is blue-black, containing white kernels, harvested in the seventh lunar month.
Chen Cheng stated: The kernel tastes like coconut. Physicians also utilize the shell.
Li Shizhen stated: Originally originating from Hainan and Jiaozhi, it is now cultivated in Shaowu, Fujian, and Meizhou, Sichuan, where it grows easily. The vine resembles Kudzu (Ge), climbing trees. The leaves are green, similar to Acanthopanax senticosus leaves (Wujia). It flowers in the fifth lunar month, with clusters of ten to twenty light red blossoms resembling Crabapple (Haitang). The fruit is elongated with ridges; initially half-yellow, turning purple-black when mature. The kernel resembles Torreyaspermum pinetii kernel (Feiren) in shape, with the color and taste of a chestnut. If stored too long, it becomes oily and black, rendering it unusable.
[Properties and Flavor] Sweet, warm, non-toxic.
[Indications] Pediatric wu-gang (five types of malnutrition syndromes in children), turbid white urine, expelling parasites, treating diarrhea and dysentery (*Kaibao Bencao*).
Treating skin sores and tinea (Li Shizhen).
[Elucidation] Li Shizhen stated: Most anthelmintic herbs are bitter and acrid, whereas Quisqualis fruit (Shijunzi) and Torreyaspermum pinetii seeds (Feizi) are sweet yet effective against parasites, which is unique. For adults and children with parasitic infections, consuming several kernels of Quisqualis fruit on an empty stomach early in the morning during the first ten days of the lunar month is effective. Alternatively, decocting the shell for oral administration, followed by eating raw or roasted kernels the next morning, is also beneficial. One must avoid drinking hot tea, as doing so induces diarrhea. Due to its sweet flavor and warm nature, this herb not only expels parasites but also benefits the Spleen and Stomach, thereby consolidating deficiency heat and stopping diarrhea/dysentery. It is a crucial medicine for various pediatric conditions. Vulgar physicians claim that excessive parasite elimination impairs digestion; this is a vulgar and ignorant statement. Just as trees have borers, houses have ants, and states have thieves—whether these are blessings or curses can be analogized. Cultivators of longevity first eliminate the Three Corpses (San Shi); the principle is analogous.
[Attached Prescriptions] Six new prescriptions.
Pediatric Pi-gang (Spleen Malnutrition): Equal parts Quisqualis fruit (Shijunzi) and Aloe (Luhui), powdered. Take one qian with rice water (*Rumen Shiqin*).
Emaciation and sallow complexion progressing to Gang disease: 3 qian of Quisqualis kernel, 5 qian of Momordica charantia seed kernel (Mubiezi), powdered. Form pills the size of longan fruits. Take one pill per dose: crack an egg, insert the pill inside, steam thoroughly over rice, and consume on an empty stomach (*Jianbian Danfang* by Yang Qi).
Pediatric ascariasis pain with salivation: Powdered Quisqualis kernel, taken at dawn (wugeng) mixed with rice water, one qian (*Quanyou Xinjian*).
Pediatric edema with swelling of the head, face, and scrotum: Use 1 liang of Quisqualis fruit, shelled, and stir-fried with 5 qian of honey until dry. Powder the mixture. Take one qian with rice soup after meals (*Jianbian Fang*).
Nasal polyps and facial sores: Soak Quisqualis kernels in a small amount of sesame oil for three to five units. Chew finely before bed and swallow with sesame oil; long-term use is effective (*Puji Fang*).
Parasitic toothache: Rinse frequently with a decoction of Quisqualis fruit (*Jijian Fang*).