七十四难曰。从其首系其数。
间象 在表 五化叠元 以应望闻
肝 青（大敦水井）臊（白泉水合）酸（中封金经）呼（大冲土俞）泣（行间水荥）
心 赤（少府火荣）焦（少冲木井）苦（少海水合）言（灵道金经）汗（神门土俞）
脾 黄（太白土俞）香（大都火荣）甘（隐白水井）歌（阴陵泉水合）涎（商丘金经）
肺 白（经渠金经）腥（大渊土俞）辛（鱼际火荣）哭（少商水井）涕（天泽水合）
肾 黑（阴谷水合）腐（复溜金经）咸（太溪土俞）呻（然谷火荣）液（涌泉水井）
六十八难曰。元证脉合。复生五象。
井（心下满）胆（元证） 身热 体重（节痛）喘嗽（寒热）逆气（泄）荣（身热）心下满（小肠）元
证体重 寒热 逆气
俞（体重节痛）心下满（胃）身热 元证 寒热 逆气
经（喘咳寒热）心下满（大肠）身热 体重 元证 逆气
合（逆气而泄）心下满（膀胱）身热 体重 寒热 元证
假令胆病善洁。面青善怒。（元证）得弦脉。（脉合）又病心下满。（当刺胆井）如见善洁面
青善
怒。脉又弦又病身热。（当利胆荣）又病体重节痛。（当刺胆俞）如见善洁面青善怒。脉又弦又
病喘咳寒热。（当刺胆合）余经例仿此。假令肝经淋溲便难转筋。春刺井。夏刺荣。秋刺经。
冬刺合。
【五音五色五化对应表】
位于体表的征象，通过五行之气的叠加变化来对应望诊和闻诊的内容：
肝脏：青色（井穴大敦属水），臊味（合穴泉门属水），酸味（经穴中封属金），呼出声（俞穴大冲属土），哭泣声（荥穴行间属水）。
心脏：赤色（荥穴少府属火），焦味（井穴少冲属木），苦味（合穴少海属水），言语声（经穴灵道属金），汗液（俞穴神门属土）。
脾脏：黄色（俞穴太白属土），香味（荥穴大都属火），甘味（井穴隐白属水），歌声（合穴阴陵泉属水），涎液（经穴商丘属金）。
肺脏：白色（经穴经渠属金），腥味（俞穴太渊属土），辛味（荥穴鱼际属火），哭声（井穴少商属水），涕液（合穴尺泽属水）。
肾脏：黑色（合穴阴谷属水），腐味（经穴复溜属金），咸味（俞穴太溪属土），呻吟声（荥穴然谷属火），尿液/津液（井穴涌泉属水）。
《难经》第六十八难说：五输穴的主证与脉象相合，进而衍生出五种征象。
井穴主证：心下痞满；胆经井穴主证为……；身体发热；体重沉重（或关节疼痛）；气喘咳嗽（或寒热往来）；气逆（或泄泻）；营分病变表现为身体发热；心下痞满与小肠有关；……
体重沉重、寒热往来、气逆等症状也出现在其他穴位的主治中。
俞穴主证：体重沉重、关节疼痛；心下痞满与胃有关；身体发热；……寒热往来、气逆。
经穴主证：气喘咳嗽、寒热往来；心下痞满与大肠有关；身体发热；体重沉重；……气逆。
合穴主证：气逆且伴有泄泻；心下痞满与膀胱有关；身体发热；体重沉重；寒热往来；……
举例来说，如果患有胆病，表现为爱干净、面色发青、容易发怒（这是胆病的典型征象），切得弦脉（这是脉象相符），并且伴有心下痞满的症状（应当针刺胆经的井穴）。如果见到患者爱干净、面色发青、容易发怒，脉象又呈弦象，并且伴有身体发热的症状（应当清利胆经的荥穴）。如果又出现体重沉重、关节疼痛的症状（应当针刺胆经的俞穴）。如果见到患者爱干净、面色发青、容易发怒，脉象又呈弦象，并且伴有气喘咳嗽、寒热往来的症状（应当针刺胆经的合穴）。其他经脉的情况都仿照这个例子。
再比如肝经病变，出现小便淋漓不畅、排便困难、筋脉拘挛抽搐等症状。春季应针刺井穴，夏季应针刺荥穴，秋季应针刺经穴，冬季应针刺合穴。
The Seventy-fourth Difficulty states: Determine the acupoints for acupuncture based on the location of the disease.
[Correspondence Table of Five Sounds, Five Colors, and Five Transformations]
Manifestations at the exterior are matched with observation (Wang) and listening/smelling (Wen) through the overlapping changes of the Five Elements (Wu Xing):
Liver: Green color (Jing-Well point Dazhun [LR1], Water element); Fishy odor (He-Sea point Quanmen [GB24? Note: Text says Baiquan Shui He, likely a specific textual variant or error in source, usually GB24 is He-Sea but belongs to Gallbladder. Here attributed to Liver context in text structure, but anatomically Dazhun is LR1. The text lists "Baiquan Shui He" which might refer to a specific point or is a typo for a Gallbladder point, but strictly translating the text's attribution]: White water spring He-Sea point, Water element); Sour taste (Jing-River point Zhongfeng [LR4], Metal element); Shouting sound (Shu-Stream point Dachong [LR3], Earth element); Crying sound (Ying-Spring point Xingjian [LR2], Water element).
Heart: Red color (Ying-Spring point Shaofu [HT8], Fire element); Scorched odor (Jing-Well point Shaochong [HT9], Wood element); Bitter taste (He-Sea point Shaohai [HT3], Water element); Speech sound (Jing-River point Lingdao [HT4], Metal element); Sweat (Shu-Stream point Shenmen [HT7], Earth element).
Spleen: Yellow color (Shu-Stream point Taibai [SP3], Earth element); Fragrant odor (Ying-Spring point Dabu [SP2], Fire element); Sweet taste (Jing-Well point Yinbai [SP1], Water element); Singing sound (He-Sea point Yinlingquan [SP9], Water element); Saliva/Drool (Jing-River point Shangqiu [SP5], Metal element).
Lung: White color (Jing-River point Jingqu [LU8], Metal element); Raw/Fishy odor (Shu-Stream point Taiyuan [LU9], Earth element); Pungent taste (Ying-Spring point Yuji [LU10], Fire element); Crying sound (Jing-Well point Shaoshang [LU11], Water element); Nasal discharge (He-Sea point Chize [LU5], Water element).
Kidney: Black color (He-Sea point Yinggu [KI10], Water element); Rotten odor (Jing-River point Fuliu [KI7], Metal element); Salty taste (Shu-Stream point Taixi [KI3], Earth element); Moaning sound (Ying-Spring point RanGu [KI2], Fire element); Urine/Essence (Jing-Well point Yongquan [KI1], Water element).
The Sixty-eighth Difficulty states: The indications of the Five Shu points correspond with the pulse, thereby generating five manifestations.
Jing-Well points indicate: Fullness below the heart; Gallbladder Jing-Well indication...; Fever; Heavy body (or joint pain); Asthma and cough (or alternating cold and heat); Rebellious Qi (or diarrhea); Ying-level pathology manifests as fever; Fullness below the heart relates to the Small Intestine...
Heavy body, alternating cold and heat, and rebellious Qi also appear in the indications of other points.
Shu-Stream points indicate: Heavy body and joint pain; Fullness below the heart relates to the Stomach; Fever... Alternating cold and heat, rebellious Qi.
Jing-River points indicate: Asthma, cough, alternating cold and heat; Fullness below the heart relates to the Large Intestine; Fever; Heavy body... Rebellious Qi.
He-Sea points indicate: Rebellious Qi accompanied by diarrhea; Fullness below the heart relates to the Bladder; Fever; Heavy body; Alternating cold and heat...
For example, if one suffers from Gallbladder disease, manifesting as a preference for cleanliness, a greenish complexion, and irritability (typical signs of Gallbladder disease), and the pulse is wiry (pulse matches), and there is accompanying fullness below the heart (one should needle the Jing-Well point of the Gallbladder channel). If one observes a preference for cleanliness, greenish complexion, irritability, a wiry pulse, and accompanying fever (one should drain the Ying-Spring point of the Gallbladder). If there is additionally heavy body and joint pain (one should needle the Shu-Stream point of the Gallbladder). If one observes a preference for cleanliness, greenish complexion, irritability, a wiry pulse, and accompanying asthma, cough, and alternating cold and heat (one should needle the He-Sea point of the Gallbladder). Other meridians follow this pattern.
Another example: If Liver channel pathology presents with dribbling dysuria, difficult defecation, and tendon spasm/cramps. In Spring, one should needle the Jing-Well point; in Summer, the Ying-Spring point; in Autumn, the Jing-River point; and in Winter, the He-Sea point.