原病式云或曰白痢既为热病何故服辛热之药亦有愈者耶盖辛热之药能开发肠胃郁结使气
液宣
流通湿润燥气和而已盖病微者可愈甚者郁结不开其病转加而死矣凡治热甚吐泻亦然夫治诸痢
者莫若以辛苦寒药治之或微加辛热佐之则可盖辛能发散开通郁结苦能燥湿寒能胜热使气宣平
而已如钱氏香连丸之类是也故治诸痢者黄连黄柏为君以其至苦大寒正主湿热之病乃若世传
辛热金石毒药治诸吐泻下痢或有愈者以其善开郁结故也然虽亦有验者或不中效反更加害
按治痢用辛苦寒之剂开郁燥湿胜热三法俱备世之用辛热金石毒药者诚非也然亦有久痢肠
胃虚滑者亦当求责
子和云夫下痢脓血腹痛不止可用调胃承气汤加姜枣煎更下藏用丸泻讫以五苓益元散调下
又一
男子泻痢不止如倾不敢冷坐诸医皆以为寒治延二十载两手寸脉皆滑余不以为寒所以寒者水也
以茶调散涌寒水五七升又以无忧散泄积水数十行乃通因通用之法也次以淡剂利水道
按此用吐下以治痢本内经通因通用之说使肠胃虚滑者其可下乎中气虚弱者其可吐乎今云
可下者谓有积滞在肠胃壅不通者也可吐者谓有痰饮在膈上气不能降以致大肠不能收敛者也
丹溪曰积湿成痰在肺中宜大肠之不固也清其源则流自清矣正是此意
丹溪曰泄痢一证局方用钟乳健脾丸朝真丹诃藜勒丸大温脾丸等药皆用热药为主治涩药为
佐使
当为肠虚感寒而成滑者设也彼泻痢者将无热证耶将无积滞耶内经曰痢有脓血多属滞下夫泻痢
证其类尤多先贤曰湿多成泄此确论也然有挟风者固不可得而同矣况风与湿之外又有杂合受邪
似难例用涩热之药局方出证有兼治里急者有兼治后重者有兼治里急后重者此岂非滞下病乎今
泻痢与滞下衮同论治实实虚虚之患将不俟终日矣经曰暴注下迫皆属于热又曰暴注皆属火又曰
下痢清白属于寒属火热者二属水寒者一泻痢一证似乎属热者多属寒者少局方专以涩热为用若
用之于下痢清白为寒者或可矣所谓下迫者即里急后重之谓也其病属火相火所为具毒甚于热矣
投以涩药非杀而何
《原病式》中说:有人问,白痢既然属于热病,为什么服用辛热性质的药物也有治愈的情况呢?这是因为辛热药物能够开发肠胃中的郁结之气,使气机和津液宣通流畅,滋润干燥,调和燥气罢了。病情轻微的可以痊愈;如果病情严重,郁结之气不能开通,那么病情就会加重而导致死亡。凡是治疗热邪极盛导致的呕吐和腹泻,也是同样的道理。
大凡治疗各种痢疾,不如用辛苦寒性质的药物来治疗,或者稍微加入一些辛热药物作为辅助即可。因为辛味能发散、开通郁结,苦味能燥湿,寒性能胜热,从而使气机宣畅平和。例如钱乙的香连丸就是这类方剂。所以治疗各种痢疾,以黄连、黄柏为君药,因为它们味道极苦、性质大寒,正主治湿热之病。至于世间流传的用辛热金石毒药治疗各种吐泻下痢,有的也能治愈,是因为它们善于开通郁结的缘故。然而虽然也有见效的,但如果不中效,反而会更加有害。
按:治疗痢疾使用辛苦寒的方剂,开郁、燥湿、胜热三法兼备。世医使用辛热金石毒药,确实是不对的。但是也有久痢导致肠胃虚弱滑脱的患者,也应当寻求其他治疗方法。
张子和说:对于下痢脓血、腹痛不止的情况,可以使用调胃承气汤加生姜、大枣煎煮,再服用藏用丸泻下。之后用五苓散合益元散调服。又有一男子,泻痢不止,如倾泻般严重,不敢坐冷处。各位医生都认为是寒证进行治疗,拖延了二十年,两手寸脉皆滑。我不认为这是寒证。所谓寒,是水饮。于是用茶调散涌吐寒水五七升,又用无忧散泄去积水数十行,这就是“通因通用”的治疗方法。随后用淡渗利水的方剂疏通水道。
按:此处用吐法和下法治疗痢疾,本是依据《内经》中“通因通用”的理论。如果是肠胃虚弱滑脱的患者,可以用下法吗?中气虚弱的患者,可以用吐法吗?现在说可以下法,是指有积滞停留在肠胃,壅塞不通的情况;说可以吐法,是指有痰饮停留在膈上,气不能下降,导致大肠不能收敛的情况。
朱丹溪说:湿气积聚成痰,存在于肺中,适宜大肠不固的情况。清除源头,水流自然清澈。正是这个意思。
朱丹溪说:泄痢这一病症,《局方》使用钟乳健脾丸、朝真丹、诃黎勒丸、大温脾丸等药物,都是以热药为主治,涩药为辅佐。这些方剂应该是为肠道虚弱感受寒邪而形成的滑脱证设立的。那些泻痢患者,难道没有热证吗?难道没有积滞吗?《内经》说:痢疾有脓血的,多属于滞下。至于泻痢证,其类别尤其多。先贤说:湿气多则形成泄泻,这是确切的论断。然而有夹杂风邪的,固然不能一概而论。况且在风与湿之外,又有杂合受邪的情况,似乎难以例用涩热药物。《局方》提出的证候,有兼治里急的,有兼治后重的,有兼治里急后重的,这难道不是滞下病吗?现在将泻痢与滞下混同论治,会造成实证实证用补、虚证虚证用泻(实实虚虚)的祸患,恐怕不久就会发生。经文说:暴注下迫,皆属于热。又说:暴注皆属火。又说:下痢清白属于寒。属于火热的是两种,属于水寒的是一种。泻痢一证,似乎属热的多,属寒的少。《局方》专门以涩热为用途,如果用于下痢清白属寒的患者或许还可以。所谓“下迫”,就是指里急后重。这种病属于火,是相火所为,毒性比热更甚。投以涩药,岂不是等于杀人吗?
*Yuan Bing Shi* (Treatise on the Original Causes of Disease) states: Someone asked, "Since white dysentery is a heat disease, why are there cases where administering acrid-hot medicines also result in recovery?" This is because acrid-hot medicines can open up stagnation and knotting in the stomach and intestines, allowing the qi and fluids to circulate freely, moisten dryness, and harmonize the dry qi. If the pathogen is mild, recovery is possible; however, if the condition is severe and the stagnation cannot be resolved, the disease will worsen, leading to death. The same principle applies to treating vomiting and diarrhea caused by extreme heat.
Generally, when treating various types of dysentery, it is best to use bitter, acrid, and cold medicines, or slightly add acrid-hot medicines as adjuvants. Acrid flavors can disperse and open stagnation; bitter flavors can dry dampness; cold properties can overcome heat. This allows the qi to circulate smoothly and peacefully. For example, Qian Yi's *Xianglian Wan* (Fragrant Coptis Pill) belongs to this category. Therefore, for treating various dysenteries, *Huanglian* (Coptidis Rhizoma) and *Huangbai* (Phellodendri Cortex) serve as sovereign drugs, as their extreme bitterness and great coldness directly address damp-heat conditions. As for the worldly practice of using acrid-hot mineral and metal toxic drugs to treat various vomiting, diarrhea, and dysentery, some may recover because these substances are good at opening stagnation. However, although some show efficacy, if they fail to work, they may cause further harm.
In analysis: Treating dysentery with bitter, acrid, and cold formulas encompasses three methods: resolving stagnation, drying dampness, and overcoming heat. It is indeed incorrect for physicians of the world to use acrid-hot mineral and metal toxic drugs. Nevertheless, for patients with chronic dysentery resulting in deficiency and slipping of the stomach and intestines, other treatment approaches should be sought.
Zi He said: For dysentery with pus and blood accompanied by unceasing abdominal pain, one may use *Tiaowei Chengqi Tang* (Regulate the Stomach Order Qi Decoction) added with ginger and jujube, decocted, followed by the administration of *Zangyong Wan* (Store Use Pill) to induce purgation. Thereafter, administer *Wuling San* (Five-Ingredient Powder with Poria) combined with *Yiyuan San* (Benefit Origin Powder) mixed with water. In another case, a male patient suffered from incessant diarrhea and dysentery, flowing like a pour, and dared not sit on cold surfaces. All physicians treated it as a cold syndrome, delaying care for twenty years. His pulses at both cun positions were slippery. I did not consider it a cold syndrome. What is considered 'cold' here is actually water retention. Thus, I used *Chatiao San* (Tea Regulation Powder) to induce emesis, expelling five to seven sheng of cold water, and then used *Wuyou San* (Carefree Powder) to drain accumulated water, resulting in dozens of bowel movements. This is the method of "treating obstruction with unblocking agents" (Tong Yin Tong Yong). Subsequently, bland diuretic formulas were used to benefit the water passages.
Analysis: Using emesis and purgation to treat dysentery originates from the *Neijing*'s (Classic of Internal Medicine) concept of "treating obstruction with unblocking agents." Can purgation be used for patients with deficient and slipping stomach and intestines? Can emesis be used for those with weak middle qi? When it is stated that purgation is applicable, it refers to cases where accumulation and stagnation block the stomach and intestines, preventing free flow. When it is stated that emesis is applicable, it refers to cases where phlegm-fluids reside above the diaphragm, preventing qi descent, thereby causing the large intestine to lose its ability to consolidate.
Danxi said: Accumulated dampness transforms into phlegm residing in the lungs, which predisposes to instability of the large intestine. Clearing the source ensures the flow becomes clear naturally. This embodies the correct meaning.
Danxi said: Regarding the syndrome of diarrhea and dysentery, *Ju Fang* (Formulas of the Bureau of Medical Relief) employs medicines such as *Zhongru Jianpi Wan* (Oyster Shell Spleen-Strengthening Pill), *Zhaozhen Dan*, *Helile Wan*, and *Da Wenpi Wan*. These primarily use hot medicines as sovereigns and astringent medicines as assistants. These prescriptions seem designed for cases of intestinal deficiency compounded by cold invasion leading to slipping. Do patients with diarrhea and dysentery lack heat syndromes? Do they lack accumulation and stagnation? The *Neijing* states: Dysentery with pus and blood mostly belongs to *Lixia* (Dysentery with tenesmus). The categories of diarrhea and dysentery are numerous. Ancient sages stated: "Excessive dampness leads to diarrhea," which is an accurate conclusion. However, cases complicated by wind pathogens certainly cannot be treated uniformly. Moreover, beyond wind and dampness, there are complex combinations of pathogenic factors, making it difficult to uniformly apply astringent and hot medicines. *Ju Fang* addresses syndromes including urgency (*lijí*), heaviness in the rectum (*houchong*), or both. Are these not *Lixia* (dysentery)? Now, equating diarrhea/dysentery with *Lixia* in treatment leads to the error of reinforcing excess and depleting deficiency (*Shi Shi Xu Xu*), a disaster that will not wait long. The Classics state: "Violent diarrhea and downward pressure belong to heat." Also: "Violent diarrhea belongs to fire." Also: "Clear and white dysentery belongs to cold." Two categories belong to fire/heat, one to water/cold. In the syndrome of diarrhea and dysentery, heat seems more common than cold. *Ju Fang* specializes in astringent and hot applications. If used for clear, white dysentery attributed to cold, it might be acceptable. However, what is called "downward pressure" refers to urgency and heaviness in the rectum. This pathology belongs to fire, specifically ministerial fire, whose toxicity is greater than ordinary heat. Administering astringent medicines in such cases is tantamount to killing.