严用和云素问谓疟生于风又夏伤于暑此四时之气也或乘凉饮冷当风卧湿饥饱失时致脾胃
不和痰积中脘遂成此疾所谓无痰不成疟一日一发易治间日一发难愈三日一发者尤其难愈
按此谓胃气不和痰积中脘而成疟则自内而生病于外也与素问风暑外伤虽异然外既受伤则
内气
必郁亦生痰此自外而生病于内也疟而挟痰诚有之矣其引以无痰不成疟之一句则失之偏也其用
药治法亦且未详
病机机要云经曰夏伤于暑秋必 疟伤之浅者近而暴伤之重者远而为 者久疟也是知夏
伤暑气
闭而不能发泄于外邪气内行至秋而为疟也有中三阳者有中三阴者其证各殊同伤寒也在太阳经
谓之寒疟治多汗之在阳明经谓之热疟治多下之在少阳经谓之风疟治多和之此三阳受病谓之暴
疟发在夏至后处暑前此乃伤之浅者近而暴也在阴经则不分三经总谓之湿疟当从太阴经论之发
在处暑后冬至前此乃伤之重者远而为 者老也居西方宜毒药疗之
按此分风暑所伤有阴阳浅深之异发前人所未论也
详见后论中
子和云内经既以夏伤于暑而为疟何世医皆以脾寒治之用姜附硫黄之类甚者归之祟怪良可
笑耶
又或因夏月饮食生冷之类指为食疟此又非也岂知内经之论则不然皆夏伤于暑遇秋风寒而后作
也邪热浅则连日邪热深则间日并入于里则寒并入于表则热若此论则了不相干于脾也治平之时
其
民夷静虽用砒石辰砂有毒之药以热治热亦能取效扰攘之时其民劳苦内火与外火俱动以热攻热
转为吐血泻血疮疡呕吐之疾岂与夷静之人同治哉余尝用张长沙汗吐下三法愈疟病极多大忌错
作脾寒治之
按此云无脾寒及鬼疟皆是得之于暑又谓平治与扰攘之时治疟不同皆确论也然食疟则世亦
有之
者然观其用药以白虎加人参汤小柴胡五苓桂苓甘露之类则调之也甚者脏用承气大紫胡下之更
不愈以常山散吐之悉是寒药降火之剂盖以疟从火之化也又有谓治刍荛贫贱之人与富贵膏粱不
同之论固是然仍用温脾散辰砂丹劫药贫贱之人岂与治平时人同欤贫贱者脾胃虚寒其可用劫剂
欤此恐非出于子和之笔也学人试思之
或问俗以疟为脾寒何也曰此亦有理天地之间惟吴楚闽广人患此至多为阳气之所盛处其地
卑湿
长夏之时人多患 疟霍乱泻痢伤湿热也本暑盛阳极人伏阴在内脾困体倦腠理开发或因纳凉于
水间木阴及泉水澡浴而微寒客于肌肉之间经所谓遇夏气凄怆之小寒迫之是也或劳役饥饱内伤
而即病作故指肌肉属脾发则多恶寒战栗乃谓之脾寒尔实由风寒湿 之邪郁于腠理夏时毛窍疏
通而不为病至秋气敛之际表邪不能发越故进退不已往来寒热病势如凌疟人之状所以名疟即
四时之伤寒故十二经皆能为病古方治法多兼于理内伤取效脾胃和而精气疏通阴阳和解诸邪悉
散此实非脾病也但病气随经升降其发早暮日次不等内经具病例已详专世以发表解肌温经散寒
等法亦未尝执于燥脾劫剂也又曰既疟本夏伤于暑为病世有不服药饵或人与符咒厌之亦止何也
曰此夏时天地气交百物生发湿热熏蒸禽虫吐毒之际人因暑热汗出神气虚耗感得时间乖戾之气
为病故与厌之亦止若移精变气之谓也然古人称疟不得为脾寒者正恐人专于温脾之说不明造化
之源而失病机气宜之要故也
严用和说:《素问》提到疟疾生于风邪,又说是夏季感受暑气,这是四时之气的影响。有的人乘凉、饮冷,当风而卧、处于潮湿环境,或者饥饱无常,导致脾胃不和,痰湿积聚在中脘,于是形成这种疾病。这就是所谓的“无痰不成疟”。一天发作一次的容易治疗,隔天发作一次的就难痊愈,三天发作一次的就更加难愈。
按语:这里说胃气不和、痰积中脘而成疟,是从内部生病而表现于外部;与《素问》所说风暑从外部侵袭虽然不同,但既然外部受了邪气,内部的正气必然郁结,也会生痰,这是从外部生病而影响内部。疟疾夹杂痰湿确实存在,但引用“无痰不成疟”这一句则失之偏颇。其用药治法也没有详细说明。
《病机机要》说:经文记载:“夏季伤于暑气,秋季必定发生疟疾。”受伤轻浅的,发病近且急;受伤重的,发病远且久。由此可知,夏季暑气闭郁不能发泄于外,邪气内行,到了秋天就发为疟疾。其中有侵犯三阳经的,有侵犯三阴经的,证候各不相同,如同伤寒一样。在太阳经称为寒疟,治疗多用发汗法;在阳明经称为热疟,治疗多用攻下法;在少阳经称为风疟,治疗多用和解法。这三阳经受病称为暴疟,发作在夏至后、处暑前,这是受伤轻浅、发病近且急的情况。在阴经受病则不分三经,总称为湿疟,应当从太阴经来论述。发作在处暑后、冬至前,这是受伤重、发病远且久的情况。居住在西方的人适宜用毒药治疗。
按语:这里区分了风暑所伤有阴阳、浅深、轻重的不同,阐发了前人未曾论述的观点。详见后文论述。
张子和说:《内经》既然认为疟疾是因为夏季伤于暑气所致,为什么后世医生都用脾寒来治疗?使用干姜、附子、硫黄之类的药物,严重的甚至归结为鬼神作祟,这真是可笑啊!
另外,有人因为夏季饮食生冷之类,将其指为食疟,这也不对。哪里知道《内经》的论述并非如此,都是夏季伤于暑气,遇到秋风寒邪而后发作。邪热浅则连日发作,邪热深则隔天发作,并入于里则恶寒,并入于表则发热。如果像这样解释,那就完全与脾无关了。在太平时期,百姓安宁,即使使用砒石、辰砂等有毒的药物以热治热,也能取得疗效;但在动乱时期,百姓劳苦,内火与外火俱动,以热攻热反而会导致吐血、泻血、疮疡、呕吐等疾病,怎么能与安宁时期的病人同样治疗呢?我曾经用张仲景的汗、吐、下三法治愈了很多疟疾病人,非常忌讳错误地当作脾寒来治疗。
按语:这里说没有脾寒及鬼疟,都是得之于暑气,又说太平时期与动乱时期治疗疟疾不同,都是确切的论述。然而食疟世间也确实存在。观察他使用的药物,如白虎加人参汤、小柴胡汤、五苓散、桂苓甘露饮之类,都是调理性质的。病情严重的用承气汤或大柴胡汤攻下,更不愈的用常山散催吐,全都是寒凉降火的方剂,大概是因为疟疾从火化而来。又有说治疗贫贱草野之人与富贵膏粱之人不同的理论,固然是对的,但仍然使用温脾散、辰砂丹等劫药,对于贫贱之人难道能与治疗平时的人相同吗?贫贱者脾胃虚寒,岂可用劫剂呢?这恐怕不是出于张子和的手笔,学习者请仔细思考。
有人问:世俗认为疟疾是脾寒,为什么呢?回答说:这也是有道理的。天地之间,只有吴楚闽广地区的人患此病最多,这是因为阳气旺盛的地方,地势低洼潮湿。长夏之时,人们多患疟疾、霍乱、泻痢,损伤湿热。此时暑气极盛,阳极则伏阴在内,脾困体倦,腠理开发。有的人在水边纳凉,或在树荫下、泉水中洗澡,微寒客于肌肉之间,这就是《内经》所说的“遇夏气凄怆之小寒迫之”。或者因劳役、饥饱内伤而立即发病,所以指肌肉属脾,发作时多恶寒战栗,因此称之为脾寒。实际上是由风寒湿邪郁于腠理,夏季毛窍疏通而不发病,到了秋气收敛之际,表邪不能发散,所以进退不已,往来寒热,病势如凌虐人之状,所以名为疟,即四时的伤寒,故十二经都能为此病。古方治法多兼于理内伤,取效在于脾胃调和而精气疏通,阴阳和解,诸邪悉散,这实在不是脾的病。只是病气随经络升降,发作早晚日期不等,《内经》病例已详述。世人只用发表解肌、温经散寒等方法,也未曾执着于燥脾劫剂。又问:既然疟疾本是夏季伤于暑气所致,世间也有不服药饵,或者让人念符咒厌胜它就停止的,为什么呢?回答说:这是因为夏季天地气交,百物生发,湿热熏蒸,禽虫吐毒之际,人因暑热汗出,神气虚耗,感得时间乖戾之气为病,所以用厌胜之法也能停止,这就是所谓移精变气的方法。然而古人称疟疾不得为脾寒,正是担心人们专门执着于温脾的说法,不明白造化的本源,而失去病机气宜的要领。
Yan Yonghe stated: The *Suwen* (Basic Questions) mentions that malaria arises from wind pathogens, and also states that it results from summer heat injury. These are influences of the qi of the four seasons. Some people cool themselves, drink cold substances, lie in the wind, dwell in dampness, or suffer from irregular eating habits, leading to disharmony of the spleen and stomach and accumulation of phlegm-dampness in the middle jiao (middle burner), thus forming this disease. This is what is meant by "no phlegm, no malaria." Malaria occurring once a day is easy to treat; occurring every other day is difficult to cure; occurring every three days is even more difficult to cure.
Commentary: Here, it is said that malaria is formed due to disharmony of stomach qi and accumulation of phlegm in the middle jiao, meaning illness originates internally and manifests externally. Although different from the *Suwen*'s description of wind and summer heat invading from the exterior, once the exterior is injured, internal qi must become stagnant, which also generates phlegm; this means illness originates externally and affects internally. It is true that malaria can be complicated by phlegm, but citing the phrase "no phalkm, no malaria" is biased. The medication and treatment methods are not detailed.
*Bingji Jiyao* (Essentials of Pathogenesis) states: The classic says, "Summer injury by summer heat leads to malaria in autumn." If the injury is shallow, onset is near and sudden; if severe, onset is distant and prolonged. Thus, it is known that summer heat qi becomes closed and cannot vent outward; the pathogen moves inward, and upon reaching autumn, malaria erupts. There are cases involving the Three Yang meridians and those involving the Three Yin meridians, with distinct syndromes, similar to Cold Damage (Shanghan). Involvement of the Taiyang meridian is called Cold Malaria, treated mostly with sweating methods; involvement of the Yangming meridian is called Heat Malaria, treated mostly with purgation methods; involvement of the Shaoyang meridian is called Wind Malaria, treated mostly with harmonizing methods. Illness in these Three Yang meridians is called Sudden Malaria, occurring between Summer Solstice and End of Heat, representing shallow injury with near and sudden onset. Involvement of the Yin meridians, regardless of the specific meridian, is collectively called Damp Malaria, discussed primarily through the perspective of the Taiyin meridian. Occurring between End of Heat and Winter Solstice, this represents severe injury with distant and prolonged onset. Those residing in the West are suitable for treatment with toxic drugs.
Commentary: This distinguishes the differences in yin/yang, depth/shallowness, and severity of wind and summer heat injuries, expounding on points not previously discussed. See further discussion below.
Zi He (Zhang Congzheng) said: Since the *Neijing* (Inner Canon) attributes malaria to summer heat injury in summer, why do later physicians all treat it as Spleen Cold? Using herbs such as Ganjiang (Dried Ginger), Fuzi (Prepared Aconite Root), and Liuhuang (Sulfur), and in severe cases attributing it to demonic influence, is truly laughable!
Furthermore, some attribute it to Food Malaria because of consuming raw and cold foods in summer, which is also incorrect. Does one not know that the *Neijing* does not say this? All cases involve summer heat injury followed by onset upon encountering autumn wind-cold. If pathogenic heat is shallow, it occurs daily; if deep, it occurs every other day. Entering interior causes chills; entering exterior causes fever. Such explanations have nothing to do with the Spleen. In times of peace, when people are tranquil, even using toxic drugs like Pishi (Realgar) and Chensha (Cinnabar) to treat heat with heat can yield results. However, in times of turmoil, when people are laborious and suffering, internal fire and external fire move together; treating heat with heat may turn into hematemesis, hematochezia, sores, ulcers, and vomiting. How can they be treated the same as tranquil people? I once used Zhang Zhongjing's sweating, vomiting, and purging methods to cure many malaria patients. It is strictly forbidden to mistakenly treat it as Spleen Cold.
Commentary: This states there is no Spleen Cold or Ghost Malaria, but rather acquisition from summer heat, and that treatment differs between peaceful and turbulent times; these are accurate discussions. However, Food Malaria does exist in the world. Observing his medications, such as Baihu Jia Renshen Tang (White Tiger Plus Ginseng Decoction), Xiaochaihu Tang (Minor Bupleurum Decoction), Wuling San (Five-Ling Powder), Guiling Ganlu Yin (Cassia Twig and Poria Sweet Dew Drink), these are regulating agents. For severe cases, Chengqi Tang (Chengqi Decoction) or Dachaihu Tang (Major Bupleurum Decoction) are used for purging; if still uncured, Changsan San (Changshan Powder) is used to induce vomiting. All are cold-natured drugs that descend fire, likely because malaria transforms from fire. There is also a theory that treating poor/commoners differs from treating wealthy/nourished individuals. While correct, using Wenspi San (Warm Spleen Powder) and Chensha Dan (Cinnabar Pill), which are coercive drugs, on poor people—can they be treated the same as ordinary people? Poor people have deficient-cold spleen and stomach; how can coercive drugs be used? This is likely not written by Zi He; students should ponder this.
A question was asked: Why do common people consider malaria to be Spleen Cold? The answer is: There is reason for this. Among all regions under heaven, only Wu, Chu, Min, and Guang regions have the highest incidence, because these are places where yang qi is abundant, terrain is low and damp. During late summer, people often suffer from malaria, cholera, and dysentery, damaging them with damp-heat. At this time, summer heat is extreme; extreme yang implies hidden yin within, causing spleen stagnation and fatigue, and opening of the cou li (pores). Some cool off by water, rest in tree shade, or bathe in springs, allowing slight cold to lodge in the muscles. This is what the Classic calls "encountering the chilling small cold of summer air pressing upon one." Or, illness arises immediately due to internal injury from labor or irregular diet. Therefore, muscles are attributed to the Spleen; during attacks, there is often aversion to cold and shivering, hence called Spleen Cold. Actually, it is caused by wind-cold-damp pathogens stagnating in the cou li. In summer, pores are open and no disease occurs; when autumn qi converges, exterior pathogens cannot vent, so they advance and retreat endlessly, causing alternating chills and fever. The condition feels like the person is being tormented, hence named Malaria, which is essentially Cold Damage of the four seasons; thus, all twelve meridians can be affected. Ancient formulas often combine regulation of internal injury. Efficacy lies in harmonizing the spleen and stomach, unblocking essence and qi, reconciling yin and yang, and dispersing all pathogens. This is truly not a disease of the Spleen itself. Only the pathogenic qi ascends and descends along the meridians, with varying onset times. The *Neijing* details these cases thoroughly. People generally use only exterior-releasing, muscle-relaxing, meridian-warming, and cold-dispersing methods, without adhering strictly to drying-spleen coercive agents. Another question: Since malaria is fundamentally caused by summer heat injury in summer, why do some stop the disease without medicine, or by having others chant spells to suppress it? The answer is: This is because in summer, heaven and earth qi interact, all things grow, damp-heat steams, and birds/insects release toxins. Due to summer heat and sweating, spirit and qi are depleted; one contracts erratic qi from the environment. Thus, suppression methods can also stop it, which is referred to as "shifting spirit and changing qi." However, ancients stated malaria should not be considered Spleen Cold precisely to prevent people from exclusively focusing on warming the spleen, failing to understand the source of creation, and missing the essentials of pathogenesis and qi suitability.