东垣曰仲景论内外不足发热自汗之证大禁发汗若饮食劳倦杂病发热自汗表虚之证认作有
余便用麻黄发之汗大出则表益虚也
谨按仲景论伤寒分例不可发汗者三十余条至一证有二禁者若寒热有血弱气虚者也况杂病
乎然误则致逆为祸至速所谓一逆尚引日再逆促命期矣
东垣云冯内翰之侄栎同病伤寒目赤而烦渴脉息七八至按之不鼓击经曰脉至而从按之不鼓
诸阳皆然此阴盛格阳于外非热也与姜附之剂汗出而愈(详见试效方)
按此与王海藏治狂言发斑身热脉沉细阴证例同东垣又有治脚膝痿弱下尻臀皆冷阴汗臊臭
精滑
不固脉沉数有力为火郁于内逼阴向外为阳盛拒阴用苦寒药下之者此水火征兆之微脉证治例之
妙王太仆曰纪于水火余气可知因并录之以劝
此事难知曰一身尽热先太阳也从外而之内者先无形也为外伤
谨按仲景论伤寒证例三阴俱有发热但微甚不同赵氏曰论中三阳皆有发热如少阴二证外又
有吐
利手足不逆冷反发热者不死少阴病一身手足尽热以热在膀胱必便血少阴病四逆散中用柴胡亦
有治发热意又厥阴病先厥后发热而利者必自止下利脉数有微热汗出今欲愈面赤身微热为郁冒
呕而发热小柴胡与夫太阴病中风四肢烦疼是三阴皆有发热明矣但寒伤阴经发热则为逆
手足不和两胁俱热如火先少阳也从内而之外者先有形也为内伤
内经曰人数醉若饱以入房气聚于脾中不得散酒气与谷气相搏热盛于中故热遍于身内热而
溺赤也
饮食不节起居不时者阴受之入六腑则身热不得卧上为喘呼
活人书曰伤食令人头痛脉数发热但左手人迎脉平和身不疼痛是也
难知曰脉人迎气口俱紧盛或举按皆实大发热而恶寒腹不和而口液此内外俱伤也
按以上辨内伤外感(详见内伤门)
内经曰身热脉弦数战栗而不恶寒者瘅疟也
要略曰发热身疼而身如熏黄者湿也 一身尽疼发热日晡所剧者此名风湿 汗出而身热者
风也
活人书云中脘有痰令人憎寒发热恶风自汗寸口脉浮胸痞满有类伤寒但头不痛项不强为异
孙尚云虚烦与伤寒相似身热脉不浮紧不恶寒但热而烦或不烦头不痛 香港脚为病大便坚脚
膝肿痛两胫或有肿满或枯细者方其发时亦有发热憎寒呕恶似伤寒证也
难经曰发热恶寒脉来浮数者温病也身热头疼自汗多眠阳脉浮滑阴脉濡弱者风温也
李东垣说:张仲景在论述因内伤或外感导致的正气不足、发热自汗的证候时,严禁使用发汗法。如果是饮食不节、劳倦过度引起的杂病,出现发热自汗且表虚的证候,如果误认为是实证而使用麻黄来发汗,导致大汗淋漓,那么体表的气血会更加虚弱。
我谨按:张仲景在《伤寒论》中论述了三十多条不可发汗的条文,甚至有一种证候包含两种禁忌(如寒热往来兼有血弱气虚)。何况是杂病呢?一旦误治就会造成逆证,祸患发生得非常迅速,正所谓“一次误治尚能拖延时日,再次误治则危及生命”。
李东垣记载:冯内翰的侄子栎同患有伤寒,症状为眼睛发红、烦躁口渴,脉搏跳动极快(每呼吸七八次),重按之下脉搏无力鼓动。《内经》说:“脉象表面看似顺从(浮大),但重按却无力鼓动,这是诸阳经皆有的现象。”这属于阴寒内盛、格拒阳气于外的假热证,并非真热。给予干姜、附子等温热药物治疗后,患者出汗而痊愈。(详见《试效方》)
按语:此案例与王海藏治疗的狂言乱语、发斑疹、身热但脉象沉细的阴证案例相同。李东垣还有治疗下肢痿弱、臀部及会阴部寒冷、阴汗腥臭、精关不固的案例;以及脉象沉数有力,判断为火邪郁结于内,逼迫阴液向外,表现为阳盛拒阴,使用苦寒药物攻下的案例。这些都是水火征兆细微之处,脉证治法的精妙体现。王冰(号太仆)曾说,记录这些水火余气的变化可知其理,因此一并录下以作劝诫。
《此事难知》说:全身尽皆发热,先由太阳经受邪引起;病邪由外向内传变,起初是无形的邪气侵袭。
我谨按:张仲景在《伤寒论》中论述伤寒证候时,三阴经都有发热,只是程度轻重不同。赵嗣真说:《伤寒论》中三阳经都有发热,如少阴病有两个证候,另外还有呕吐腹泻、手足不逆冷反而发热的,这种不会死亡;少阴病出现全身和手足都发热,是因为热邪在膀胱,必然会导致便血;少阴病四逆散中使用柴胡,也有治疗发热的意图;厥阴病先四肢厥冷后发热且伴有腹泻的,腹泻必定自行停止;腹泻脉数,微热出汗,表示将要痊愈;面部发红、身体微热、郁冒、呕吐且发热,用小柴胡汤治疗;以及太阴病中风导致四肢烦痛,这说明三阴经都有发热。但是,寒邪损伤阴经导致发热则属于逆证。
手足不和,两胁俱热如火,先由少阳经受邪引起;病邪由内向外传变,起初是有形的邪气积滞。
《内经》说:人如果在醉酒或饱食后行房事,精气聚积在脾中不得消散,酒气与谷气相互搏结,热邪盛于体内,所以全身发热,小便颜色深赤。
饮食没有节制,起居没有规律,阴气首先受邪。邪气传入六腑,则身体发热、无法安卧,向上表现为喘息呼叫。
《活人书》说:伤食会导致头痛、脉数、发热,但如果左手人迎脉平和,身体没有疼痛,就是这种情况。
《此事难知》说:人迎脉和气口脉都紧盛,或者举按都实大,发热且恶寒,腹部不适且口中津液多,这是内外都受伤的表现。
按语:以上辨别内伤和外感(详见内伤门)。
《金匮要略》说:发热、身体疼痛且面色像熏黄一样的,是湿病;全身疼痛、发热且在傍晚时分加剧的,这叫风湿;出汗且身体发热的,是风邪致病。
《活人书》说:中脘部位有痰饮,令人憎寒发热、恶风、自汗,寸口脉浮,胸膈痞满,症状类似伤寒,但头部不痛、项背不强,这是区别所在。
孙尚说:虚烦与伤寒相似,身体发热,脉象不浮紧,不恶寒,只是发热烦躁或不烦躁,头部不痛。香港脚病导致大便坚硬,脚膝肿痛,两小腿或有肿满或枯细的情况,在其发作时也有发热、憎寒、呕吐恶心等症状,类似伤寒证。
Li Dongyuan stated: Zhang Zhongjing, in discussing syndromes of fever and spontaneous sweating due to internal or external deficiency, strictly forbids the use of diaphoresis (sweating therapy). If a miscellaneous disease caused by improper diet or overwork presents with fever, spontaneous sweating, and exterior deficiency, and is mistakenly identified as an excess condition, using Ephedrae Herba (Mahuang, 麻黄) to induce heavy sweating will further deplete the exterior.
Commentary: In Zhang Zhongjing's discussion on Shaoyin Cold Damage (Shanghan), there are more than thirty clauses indicating conditions where diaphoresis is contraindicated, including cases with dual prohibitions, such as alternating chills and fever accompanied by blood deficiency and qi weakness. How much more so for miscellaneous diseases? Misdiagnosis leads to adverse reactions, causing rapid disaster, as stated: "One error may prolong life for a while, but two errors will shorten it."
Li Dongyuan recorded: The nephew of Hanlin Academician Feng, named Li Tong, suffered from cold damage with red eyes, irritability, thirst, and a pulse rate of seven to eight beats per breath. Upon deep palpation, the pulse did not surge forcefully. The *Neijing* states: "When the pulse appears compliant on the surface but does not surge upon pressure, this applies to all yang meridians." This indicates Yin excess repelling Yang to the exterior, presenting as false heat rather than true heat. Treatment with warming agents containing Dried Ginger (Ganjiang) and Prepared Aconite Root (Fuzi) resulted in sweating and recovery (see *Shixiao Fang*).
Note: This case is similar to Wang Haizang's treatment of maniacal speech, macules, fever with a deep and fine pulse, indicative of a Yin syndrome. Li Dongyuan also treated cases of lower limb flaccidity, coldness in the buttocks and perineum, foul-smelling genital sweat, and seminal emission; and another case where the pulse was deep, rapid, and forceful, indicating fire郁 (stagnation) internally forcing Yin outward, presenting as Yang excess rejecting Yin, treated with bitter-cold purgatives. These illustrate the subtle signs of Water and Fire and the sophistication of pulse-syndrome-treatment correlations. Wang Bing (styled Taipu) remarked that recording these residual effects of Water and Fire reveals their principles; thus, they are recorded here for encouragement.
*Cishi Nanzhi* states: Generalized body heat initially stems from the Taiyang meridian; pathogenic factors moving from exterior to interior begin as formless invasions.
Commentary: In Zhang Zhongjing's treatise on cold damage, fever can occur in all three Yin meridians, varying in severity. Zhao Sizhen noted that fever occurs in all three Yang meridians. For example, in Shaoyin disease, vomiting and diarrhea with warm extremities and fever indicate survival; generalized heat in hands, feet, and body suggests heat in the Bladder leading to hematochezia; Chaihu Si Ni San contains Bupleuri Radix (Chaihu) for treating fever; Jueyin disease starting with cold limbs followed by fever and diarrhea implies self-resolution of diarrhea; a rapid pulse with slight fever and sweating indicates impending recovery; facial redness, slight fever, vertigo, vomiting, and fever are treated with Xiao Chai Hu Tang; and Taiyang wind-strike causing painful limbs confirms that fever exists in all three Yin meridians. However, cold damaging the Yin meridians resulting in fever is considered an adverse reaction.
Coldness in hands and feet combined with bilateral hypochondriac heat like fire initially stems from the Shaoyang meridian; pathogenic factors moving from interior to exterior begin with有形 (formative) accumulation.
The *Neijing* states: After excessive drinking or full meals, engaging in sexual activity causes essence to accumulate in the Spleen without dispersing. The interaction between alcohol qi and grain qi generates intense internal heat, causing generalized body heat and dark urine.
Irregular diet and起居 (daily routine) injure the Yin. Pathogens entering the Six Fu organs cause body heat, insomnia, and upper respiratory distress (wheezing/calling).
*Huo Ren Shu* states: Food stagnation causes headache, rapid pulse, and fever. If the Renying pulse on the left hand is peaceful and the body lacks pain, it confirms this diagnosis.
*Cishi Nanzhi* states: Both Renying and Qikou pulses are tight and vigorous, or large and solid upon lifting and pressing, accompanied by fever, aversion to cold, abdominal discomfort, and excessive salivation, indicating simultaneous internal and external injury.
Note: The above distinguishes internal injury from external contraction (see Internal Injury section).
The *Neijing* states: Fever, wiry-rapid pulse, shivering without aversion to cold characterizes Dan Malaria.
*Jingui Yaolue* states: Fever, body ache, and a complexion resembling smoked yellow indicate Dampness; generalized body ache, fever worsening at dusk indicates Wind-Dampness; sweating with body heat indicates Wind pathogen.
*Huo Ren Shu* states: Phlegm in the Zhongwan area causes aversion to cold, fever, aversion to wind, spontaneous sweating, floating Cunkou pulse, and chest stuffiness. Symptoms resemble cold damage but differ by the absence of headache and neck stiffness.
Sun Shang stated: Deficiency vexation resembles cold damage, with fever, non-floating/non-tight pulse, no aversion to cold, only fever/vexation, and no headache. Hongjiao (Beriberi) causes hard stool, swollen/painful legs, either swollen/shiny or withered/thin calves. During attacks, symptoms include fever, aversion to cold, vomiting, and nausea, resembling cold damage.
*Nan Jing* states: Fever, aversion to cold, and floating-rapid pulse characterize Warm Disease; body heat, headache, spontaneous sweating, somnolence, floating-slippery Yang pulse, and weak-soft Yin pulse characterize Wind-Warmth.