东垣云四肢发热者或口干舌干咽干盖心生大小肠生热火热来乘主位乃湿热相合故烦躁闷
乱也
四肢者脾土也火乘之故四肢发热也 或身体沉重走注疼痛盖湿热相搏而风热郁而不得伸也
谨按诸病表热有相类则脉气病本之不同也因类以上诸例是故仲景论伤寒卒病发热而恶寒
者发
于阳也其脉浮紧而涩为风寒客于荣卫之中也分六经传变脉证至二百余例有因坏误所致及温疟
风温温疫等证皆冬伤于寒发为诸脉证之变此伤寒论之所以作也河间刘守真论热病因阳气怫郁
而为热或郁结转甚而恶寒所谓亢则害承乃制阳拯反似阴与伤寒皆相类此原病式之所以作也东
垣李明之论内伤脾胃之证始得之多气高而喘身热而烦其脉洪大而头痛或渴不止其皮肤不任风
寒而生寒热与外感伤寒多相似此脾胃论之所以作也斯三君子之论本推明内经病机之旨条热证
标本之不同勿视此以为彼也然学人不审其义而各为专门是以丹溪朱先生曰学先仲景书者以伤
寒为主恐误内伤作外感先东垣书者以胃气为主恐误外感为内伤先河间书者以热为主恐误以寒
为热不若先主于内经则自然活泼泼地盖内经之义则精而博者也然则微三君子之论又何由知经
义之积隐乎但不审其义而各为专门者视此以为彼误人多矣吁丹溪之旨微哉切观仲景之法必凭
脉验证施治变化无穷深合内经之旨如寒邪在表以辛温之药汗之在里以辛热之药温之传变在半
表里者以甘寒之药和解之传变入里者以苦寒之药下之凉剂亦未尝委而不用也大抵固凭脉验证
以自通变不可执论专方如此矧人身之病有水火征兆之微若王太仆曰热来复去昼见夜伏夜发昼
见时节而动是无火也是例固河间论亢则害承乃制病式亦庶几矣丹溪更有论阴阳为恶寒非寒恶
热非热者因人身之病水火征兆幽显莫测先哲推论亦且至矣然仲景论伤寒脉法亦未尝不引杂病
河间论热证脉法而且未详学人能本仲景参叔和脉法自辨内伤外感之分殊如王海藏曰仲景言弦
涩为阴叔和言弦涩为阳虽有阴阳之别则不离诸数为热诸迟为寒仲景叔和言本两途非相违背合
而论之皆是也仲景所言伤寒自外从气而入以弦脉为阴邪从外入先太阳也叔和所言杂病自内从
血而出以弦脉为阳病自内生先少阳也如此则形证有相类脉气病本之不同学人审是则自然通变
不致视此以为彼拘于执论专方而已也
李东垣说:四肢发热,或者口干、舌干、咽干,这是因为心与小肠生热,火热之邪来侵犯主位,乃是湿热相合,所以导致烦躁闷乱。
四肢属于脾土,火邪侵犯它,所以四肢发热。或者身体沉重、游走性疼痛,这是因为湿热相互搏结,风热郁滞而不能舒展所致。
谨按:各种疾病的表热症状有相似之处,但脉象和病本却不同。因此分类以上诸例,张仲景论述伤寒卒病(急性外感热病),发热而恶寒的,是发于阳经;其脉浮紧而涩,是风寒客居于营卫之中;分为六经传变,脉证多达二百余例,有因误治坏病所致的,以及温疟、风温、温疫等证候,都是冬天感受寒邪,后来发展为各种脉证的变化,这就是《伤寒论》之所以作的原因。刘河间(刘守真)论述热病,认为病因是阳气怫郁(郁结不通)而产生热,或者郁结转甚而恶寒,所谓“亢则害,承乃制”,阳盛极反而似阴,这与伤寒症状相似,这就是《原病式》之所以作的原因。李东垣(李明之)论述内伤脾胃的证候,初起时多气高而喘,身热而烦,其脉洪大而头痛或口渴不止,其皮肤不耐风寒而生寒热,这与外感伤寒多相似,这就是《脾胃论》之所以作的原因。这三位君子的论述,根本在于推明《内经》病机的旨意,条理地分析热证标本的不同,不要把这个看作那个。然而学者不审察其义理,各自成为专门之学,所以丹溪朱先生说道:学习先读仲景书的人,以伤寒为主,恐怕误将内伤当作外感;先读东垣书的人,以胃气为主,恐怕误将外感当作内伤;先读河间书的人,以热为主,恐怕误将寒当作热。不如先以《内经》为主,则自然活泼泼地。因为《内经》的义理精博。那么没有这三位君子的论述,又从哪里知道经义的积隐呢?只是不审察其义理而各自成为专门之学的人,把这个看作那个,误人很多了。唉!丹溪的宗旨微妙啊。切观仲景的方法,必定凭脉验证,施治变化无穷,深合《内经》的旨意。如寒邪在表,用辛温的药发汗;在里,用辛热的药温之;传变在半表半里的,用甘寒的药和解;传变入里的,用苦寒的药下之。凉剂也未尝废弃不用。大抵固然凭脉验证以自通变,不可执着于固定的理论和专方。况且人身之病有水火征兆的细微差别,正如王太仆所说:“热来复去,昼见夜伏,夜发昼见,时节而动,是无火也。”这个例子确实符合河间论述“亢则害,承乃制”的病式,也差不多。丹溪更有论述阴阳为恶寒非寒、恶热非热者,因为人身之病水火征兆幽显莫测,先哲推论也已至矣。然而仲景论述伤寒脉法,也未尝不引用杂病;河间论述热证脉法,而且未详尽。学者能本于仲景,参考叔和脉法,自行辨别内伤外感的分殊。如王海藏说:仲景言弦涩为阴,叔和言弦涩为阳,虽然有阴阳之别,则不离诸数为热,诸迟为寒。仲景与叔和所言本两途,并非相违背,合而论之,皆是也。仲景所言伤寒,自外从气而入,以弦脉为阴邪,从外入先太阳也;叔和所言杂病,自内从血而出,以弦脉为阳病,自内生先少阳也。如此则形证有相似之处,但脉气和病本不同,学者审察这一点,则自然通变,不致视此以为彼,拘执于理论和专方罢了。
Li Dongyuan stated: Fever in the four limbs, or dryness of the mouth, tongue, and throat, occurs because heat arises from the Heart and Small Intestine. The pathogenic fire attacks the main position, resulting in a combination of damp-heat, which causes restlessness and confusion.
The four limbs belong to Spleen Earth; when Fire attacks them, fever in the four limbs results. Alternatively, heaviness of the body and wandering pain occur because damp-heat struggles with each other, and wind-heat is constrained and unable to extend freely.
Respectfully noted: Various diseases presenting with exterior heat may have similar symptoms, but their pulse qualities and pathological origins differ. Therefore, categorizing the above examples: Zhang Zhongjing discussed cold damage (Shanghan) and acute febrile diseases. Fever accompanied by aversion to cold indicates onset in the Yang aspect; a floating, tight, and choppy pulse indicates Wind-Cold lodging in the Ying (Nutrient) and Wei (Defensive) levels. He divided the transmission into Six Channels, detailing over two hundred pulse-syndrome patterns, including those caused by mismanagement and complications, as well as warm malaria, wind-warmth, and warm epidemics. These are all variations arising from winter cold injury manifesting later as various pulse-syndrome changes, which is why the *Treatise on Cold Damage* (*Shanghan Lun*) was written. Liu Wansu (Liu Shouzhen) discussed heat diseases, attributing them to the constraint of Yang Qi generating heat, or severe constraint causing aversion to cold. This refers to "Excess leads to harm, restraint brings regulation," where extreme Yang resembles Yin. These resemble cold damage, which is why the *Book on Original Disease Patterns* (*Yuanbing Shi*) was written. Li Dongyuan (Li Mingzhi) discussed internal injury to the Spleen and Stomach. Initially, there is often shortness of breath with panting, fever, and irritability; the pulse is large and forceful with headache or unceasing thirst. The skin cannot withstand wind and cold, leading to alternating chills and fever, which closely resembles exterior cold damage. This is why the *Treatise on the Spleen and Stomach* (*Piwei Lun*) was written. The theories of these three gentlemen fundamentally aim to elucidate the principles of disease mechanisms in the *Inner Canon* (*Neijing*), systematically distinguishing the root and branch of heat syndromes, preventing one from mistaking one for another. However, scholars who fail to examine the underlying principles become specialized in narrow fields. Thus, Master Zhu Danxi said: Those who study Zhang Zhongjing first focus on cold damage, fearing the mistake of treating internal injury as exterior excess; those who study Li Dongyuan first focus on Stomach Qi, fearing the mistake of treating exterior excess as internal injury; those who study Liu Wansu first focus on heat, fearing the mistake of treating cold as heat. It is better to prioritize the *Inner Canon*, which naturally becomes flexible and vibrant, as its principles are profound and comprehensive. Without the treatises of these three gentlemen, how would one understand the accumulated obscurities of the classics? Yet, those who fail to examine principles and become narrowly specialized mistake one for another, misleading many people. Alas, Zhu Danxi's insights are subtle. Observing Zhang Zhongjing's methods, treatment relies on pulse verification, allowing infinite variation, deeply aligning with the *Inner Canon*. For example, if cold pathogen is at the exterior, use acrid-warm herbs to induce sweating; if in the interior, use acrid-hot herbs to warm; if transmitted to the half-exterior/half-interior level, use sweet-cold herbs to harmonize; if transmitted deep into the interior, use bitter-cold herbs to purge. Cooling agents are not abandoned either. Generally, one must rely on pulse verification to achieve flexibility, rather than adhering rigidly to fixed theories or specific formulas. Moreover, human diseases present subtle signs of Water and Fire. As Wang Bing (Wai Tai Pu) stated: "Heat comes and goes, appears by day and hides by night, emerges by night and hides by day, moving with seasons—this is absence of Fire." This example aligns with Liu Wansu's discussion on "Excess leads to harm, restraint brings regulation" in the *Book on Disease Patterns*. Zhu Danxi further discussed Yin-Yang, stating that aversion to cold does not necessarily mean cold, and aversion to heat does not necessarily mean heat, because the signs of Water and Fire in the human body are obscure and unpredictable. The ancients' deductions were thorough. However, Zhang Zhongjing's pulse methodology for cold damage also cited miscellaneous diseases; Liu Wansu's pulse methodology for heat syndromes was not exhaustive. Scholars should base themselves on Zhang Zhongjing, reference He Suo's pulse methods, and distinguish between internal injury and exterior excess. As Wang Haizang said: Zhang Zhongjing considers wiry and choppy pulses as Yin, while He Suo considers them as Yang. Although there is a distinction between Yin and Yang, they do not depart from the principle that numerous pulses indicate heat, and slow pulses indicate cold. Zhang Zhongjing and He Suo approached from different paths but did not contradict each other; combined, both are correct. Zhang Zhongjing's discussion on cold damage posits that pathogens enter from the exterior via Qi, considering the wiry pulse as a Yin pathogen entering from outside, affecting the Taiyang channel first. He Suo's discussion on miscellaneous diseases posits that pathology originates internally from Blood, considering the wiry pulse as a Yang disease originating inside, affecting the Shaoyang channel first. In this way, although clinical manifestations may be similar, the pulse quality and pathological origin differ. If scholars examine this carefully, they will naturally adapt and avoid mistaking one condition for another or being confined to rigid theories and specific formulas.