因天行邪气，客于三阳之经，头目俱肿而为病也。太阳头顶、脑项赤肿，宜荆防败毒散加羌活
、本。阳明鼻额面肿，二目不开，气喘口干，普济消毒饮；内实，防风通圣散间服。少阳耳之上
下、前后、头角赤肿，寒热胁痛，小柴胡加消毒药；头面大肿、发热骨痛，冲和汤、冬麻黄汤，汗
出肿消。
天行邪气，客于少阳，颈项并腮俱肿大，如虾蟆样，故名。宜用消风清热之药，宜败毒散，倍
羌活，加酒炒黄芩、大黄，随病加减，不可峻用降药。内实虽用硝、黄，须细细呷之。如有大热狂
证，可用承气汤、白虎汤等治之，或水渍法，看轻重用。
普济消毒饮子 疫疠初觉憎寒壮热，头面渐肿，咽喉不利，服之即愈。
黄连（酒炒） 黄芩（酒炒。各五钱） 人参（三钱，无亦可） 陈皮（去白） 甘草 玄参
（各二钱） 马勃 连翘 牛蒡子 桔梗 板蓝根（各一钱） 柴胡（八分） 升麻 僵蚕（各七
分）
上为末，半用汤调，卧床慢服；半用蜜丸噙化，如上法。或加防风、川芎、薄荷、当归、细辛
，水煎服。如大便秘，加酒煮大黄（一钱或二钱）以利之。头疼骨痛、身热，宜先汗之。
二黄汤 治大头瘟。
黄连 黄芩（俱酒炒） 生甘草（等分）
上为末，每五钱水煎服，慢呷；未退加牛蒡、芒硝。加引经药∶太阳羌活、防风；阳明石膏；
少阳柴胡。渴加栝蒌根，或口干，葛根；身痛，羌活、防风、芍药。
水渍法 治内外热极（法见伤寒。）
简便方 治瘟疫瘟热。大渴欲饮水者，蚯蚓泥擂新水饮之。
又方 晚蚕沙，擂水滤清汁饮。
又方 向东桃枝叶煎汤浴，席围汗出。
又方 以真降香烧，辟邪，小儿带之。
又方 赤小豆囊置井中，三日取起，向东立，水吞。男三十粒，女二十粒。举家服之，不染瘟
疫。
瘟疫咒法（并治邪病，宜戒房室、荤酒。）
用枣一枚，咒曰∶“华表柱”，念七遍，望天罡取气一口吹枣上，令病患嚼吃，汤下。此三字
鬼之祖
名也。
宣圣辟瘟丹（孔氏六十余代用之）法以腊月二十四日五更初，取井花水，在乎旦第一汲，盛净
器中，量人口多少，浸乳香至岁旦五更，令温暖。从小至大，每人以乳香汤饮之，香一小豆块吞下
，则一年不患时疫。
五瘟丹 黄连 黄柏 黄芩 山栀 香附 紫苏 甘草梢
上七味，生为末。将大黄三倍煎汁熬膏，和丸鸡子大，朱砂、雄黄为衣，金箔贴。每用一丸，
取泉水七碗，浸化，可服七人。前方，乙庚年黄芩为君；丁壬，山栀；丙辛，黄柏；戊癸，黄连。
甲己，甘草为君者，加一倍也，余减半。
鸡子清饮 治热病。五、六日壮热之甚，狂言欲走。
鸡子（二枚，取清） 芒硝（研细） 软石膏（研细。各二钱）
上先取新汲水调硝石末，次下清，搅匀，分二服。
由于时行邪气，侵袭三阳经脉，导致头目同时肿胀而发病。太阳经受邪表现为头顶、后脑及项部红肿，适宜使用荆防败毒散加羌活、藁本。阳明经受邪表现为鼻部、前额及面部肿胀，双眼难以睁开，气喘口干，适宜使用普济消毒饮；若体内实热积滞，可交替服用防风通圣散。少阳经受邪表现为耳部上下、前后及头角红肿，伴有寒热往来和胁肋疼痛，适宜使用小柴胡汤加入清热解毒药物；若头面严重肿胀、发热且骨痛，可使用冲和汤或冬麻黄汤，待汗出则肿胀消退。
时行邪气侵袭少阳经，导致颈项及腮部同时肿大，形状如虾蟆（青蛙），因此得名。适宜使用疏风清热的药物，首选败毒散，加倍羌活用量，加入酒炒黄芩、大黄，根据病情加减，不可猛烈使用降泄药物。若体内实热虽需用芒硝、大黄，也必须细细啜饮。若出现高热狂躁症状，可使用承气汤、白虎汤等治疗，或采用水渍法，视病情轻重选用。
普济消毒饮子：适用于瘟疫初起，感觉恶寒壮热，头面逐渐肿胀，咽喉不利，服用此方即可痊愈。
黄连（酒炒） 黄芩（酒炒，各五钱） 人参（三钱，若无也可不用） 陈皮（去白） 甘草 玄参（各二钱） 马勃 连翘 牛蒡子 桔梗 板蓝根（各一钱） 柴胡（八分） 升麻 僵蚕（各七分）
将上述药材研为细末，一半用开水调服，卧床缓慢服用；另一半制成蜜丸含化，用法同上。也可加入防风、川芎、薄荷、当归、细辛，水煎服。若大便秘结，加入酒煮大黄（一钱或二钱）以通便。若头疼骨痛、身热，宜先采用发汗法。
二黄汤：治疗大头瘟。
黄连 黄芩（均酒炒） 生甘草（等分）
将上述药材研为细末，每次取五钱水煎服，缓慢啜饮；若热势未退，加入牛蒡子、芒硝。加入引经药：太阳经用羌活、防风；阳明经用石膏；少阳经用柴胡。口渴加栝蒌根，或口干加葛根；身痛加羌活、防风、芍药。
简便方：治疗瘟疫瘟热。大渴想喝水的人，用蚯蚓泥研磨后兑入新汲水饮用。
又一方：晚蚕沙研磨后加水过滤取清汁饮用。
又一方：向东生长的桃树枝叶煎汤沐浴，围坐席中出汗。
又一方：将赤小豆装入囊中放入井中，三天后取出，面向东方站立，用水吞服。男性三十粒，女性二十粒。全家服用，可不被瘟疫感染。
瘟疫咒法（兼治邪病，宜戒房事、荤腥酒类。）
用一枚枣，念咒曰：“华表柱”，念七遍，望向天罡星方向吸气一口吹在枣上，让病患嚼食，汤送下。这三个字是鬼的祖先名字。
宣圣辟瘟丹（孔氏六十余代沿用之法）：于腊月二十四日五更初，取清晨第一次汲取的井花水，盛放在干净容器中，根据人口多少浸泡乳香至元旦五更，使其温暖。从小到大，每人用乳香汤饮用，吞下一小块如大豆大小的乳香，则一年不患时疫。
五瘟丹：黄连 黄柏 黄芩 山栀 香附 紫苏 甘草梢
将上述七味药生研为细末。用三倍量的大黄煎汁熬成膏，与药末混合制成如鸡蛋大的丸剂，以朱砂、雄黄为衣，贴金箔。每次服用一丸，取七碗泉水浸泡化开，可供七人服用。前方中，乙庚年以黄芩为君药；丁壬年以山栀为君药；丙辛年以黄柏为君药；戊癸年以黄连为君药。甲己年以甘草为君药的，加一倍量，其余减半。
鸡子清饮：治疗热病。病程五、六日，壮热严重，胡言乱语欲奔跑。
鸡蛋（两枚，取蛋清） 芒硝（研细） 软石膏（研细，各二钱）
先取新汲水调匀硝石末，再加入蛋清，搅匀，分两次服用。
Due to epidemic pathogenic factors invading the three Yang meridians, swelling occurs in both the head and eyes. Invasion of the Taiyang meridian manifests as redness and swelling of the vertex, occiput, and neck; Jingfang Baidu San (Astragalus and Saposhnikovia Decoction) with Qianghuo (Notopterygii Rhizoma et Radix) and Bencao (Ligustici Chuanxiong Rhizoma) is appropriate. Invasion of the Yangming meridian manifests as swelling of the nose, forehead, and face, inability to open the eyes, panting, and dry mouth; Puji Xiaodu Yin (Great Relief Detoxification Decoction) is appropriate. If there is internal excess heat, Fengtang Tongsheng San (Saposhnikovia and Gardenia Powder for Unblocking the Interior) may be taken alternately. Invasion of the Shaoyang meridian manifests as redness and swelling above, below, before, and behind the ears, as well as at the temporal angles, accompanied by alternating chills and fever and hypochondriac pain; Xiao Chaihu Tang (Minor Bupleurum Decoction) with heat-clearing and detoxifying herbs is appropriate. If there is severe head and facial swelling, fever, and bone pain, Chonghe Tang or Dongmayang Tang may be used; once sweating occurs, the swelling subsides.
Epidemic pathogenic factors invading the Shaoyang meridian cause simultaneous swelling of the neck, nape, and parotid regions, resembling a frog (Xiamu), hence the name. It is appropriate to use wind-dispelling and heat-clearing herbs. Baiku San is preferred, with doubled Qianghuo, plus Jiu Chao Huangqin (Scutellariae Radix fried with wine) and Dahuang (Rhei Radix et Rhizoma). Dosages should be adjusted according to the condition; drastic purgative drugs should not be used vigorously. Although Mangxiao (Natrii Sulfas) and Dahuang are used for internal excess, they must be sipped slowly. If high fever and maniacal symptoms occur, Chengqi Tang (Gastrointestinal Draining Decoction) or Baihu Tang (White Tiger Decoction) may be used, or the Shuizi Fa (Water Immersion Method) may be applied depending on severity.
Puji Xiaodu Yinzi: Suitable for the initial stage of plague, characterized by aversion to cold and high fever, gradual swelling of the head and face, and throat obstruction. Taking this formula leads to recovery.
Huanglian (Scutellariae Radix, wine-fried) and Huangqin (Scutellariae Radix, wine-fried), each 5 qian; Renshen (Ginseng Radix), 3 qian (optional); Chenpi (Citri Reticulatae Pericarpium, pith removed); Gancao (Glycyrrhizae Radix et Rhizoma); Xuanshen (Scrophulariae Radix), each 2 qian; Mabo (Stemonitis Rhizoma); Lianqiao (Forsythiae Fructus); Niubangzi (Arctii Fructus); Jiegeng (Platycodonis Radix); Banlangen (Isatidis Radix), each 1 qian; Chaihu (Bupleuri Radix), 8 fen; Shengma (Cimicifugae Rhizoma); Jiangcan (Bombyx Batryticatus), each 7 fen.
Grind into powder. Half is mixed with water and taken slowly while lying down; the other half is made into honey pills for sucking. Alternatively, Fangfeng (Saposhnikoviae Radix), Chuanxiong (Ligustici Chuanxiong Rhizoma), Bohe (Menthae Haplocalycis Herba), Danggui (Angelicae Sinensis Radix), and Xixin (Asari Radix et Rhizoma) may be added and decocted in water. If constipation occurs, Jiuzhu Dahuang (Rhei Radix et Rhizoma boiled with wine), 1-2 qian, is added to promote bowel movement. For headache, bone pain, and fever, diaphoresis should be induced first.
Erhuang Tang: Treats Datouwen (Big Head Plague).
Huanglian (Scutellariae Radix) and Huangqin (Scutellariae Radix), both wine-fried; Sheng Gancao (Raw Glycyrrhizae Radix et Rhizoma), equal parts.
Grind into powder. Take 5 qian per dose, decoct in water, and sip slowly. If heat persists, add Niubangzi (Arctii Fructus) and Mangxiao (Natrii Sulfas). Add guiding herbs: Qianghuo (Notopterygii Rhizoma et Radix) and Fangfeng (Saposhnikoviae Radix) for Taiyang; Shigao (Gypsum Fibrosum) for Yangming; Chaihu (Bupleuri Radix) for Shaoyang. For thirst, add Gualougen (Trichosanthis Radix); for dry mouth, Gegen (Puerariae Lobatae Radix); for body ache, Qianghuo, Fangfeng, and Shaoyao (Paeoniae Radix).
Shuizi Fa (Water Immersion Method): Treats extreme internal and external heat (method described in Shanghan Lun).
Jianbian Fang (Simple Formula): Treats plague heat. For those with intense thirst desiring water, grind earthworm mud and mix with fresh well water for drinking.
Another formula: Grind Wancansa (Bombyx Batryticatus residue), filter the juice with water, and drink.
Another formula: Bath in decoction of peach branches and leaves growing towards the east, then sit wrapped in mats to induce sweating.
Another formula: Burn Zhen Jiangxiang (Aquilariae Lignum Resinatum) to dispel evil; children may wear it.
Another formula: Place Chi Xiaodou (Vigna Angularis Seed) in a bag and put it in a well for three days. Take it out, stand facing east, and swallow with water. Men take 30 grains, women take 20 grains. The whole family takes it to avoid plague infection.
Plague Mantra (also treats evil diseases; abstain from sexual activity, meat, and alcohol):
Take one jujube and chant: "Huabiao Zhu" (Ornamental Pillar of Hua), seven times. Inhale air facing the Tiangang star and blow onto the jujube. Let the patient chew and swallow with water. These three characters are the ancestral names of ghosts.
Xuansheng Piwen Dan (Confucius's Plague-Dispelling Pill, used by Confucius's descendants for over sixty generations): On the morning of the 24th day of the twelfth lunar month, collect the first draw of well water ("Jinghua Shui"). Soak Rushen (Frankincense) in it until the early morning of New Year's Day, keeping it warm. Everyone drinks the Rushen-infused water, swallowing a small bean-sized piece of frankincense, ensuring immunity from seasonal epidemics for one year.
Wuwen Dan (Five Plagues Pill): Huanglian (Scutellariae Radix), Huangbai (Phellodendri Cortex), Huangqin (Scutellariae Radix), Shanzhi (Gardeniae Fructus), Xiangfu (Cyperi Rhizoma), Zisu (Perillae Folium), Gancao Shao (Tip of Glycyrrhizae Radix et Rhizoma).
Grind these seven ingredients into powder. Prepare a paste by boiling three times the amount of Dahuang (Rhei Radix et Rhizoma) in water. Mix the powder with the paste to form pills the size of chicken eggs. Coat with Zhusha (Cinnabar) and Xionghuang (Realgar), and apply gold leaf. One pill is dissolved in seven bowls of spring water, sufficient for seven people. In different years, the sovereign herb changes: Huangqin in Yi-Geng years; Shanzhi in Ding-Ren years; Huangbai in Bing-Xin years; Huanglian in Wu-Gui years. In Jia-Ji years, Gancao is the sovereign herb, doubled in quantity, while others are halved.
Jizi Qing Yin (Chicken Egg White Drink): Treats febrile disease. Used when high fever peaks around the fifth or sixth day, accompanied by delirium and restlessness.
Two chicken eggs (take the white); Mangxiao (Natrii Sulfas), finely ground; Ruan Shigao (Soft Gypsum Fibrosum), finely ground, each 2 qian.
First, dissolve Mangxiao powder in fresh well water, then add the egg white, stir well, and divide into two doses.