口为脾之外窍，脾热盛故掏之。又火邪客于心肺，心火炽盛，金受火克亦掏口，宜双解散主之，回后重用生石膏。
肝肺有毒，而毒冲于胃，肺胃受毒在内，故发干呕也。
冲任之火，上犯清道，干呕无物者，此脏腑内伤。若饮食而呕，此热呕也，宜用陈皮、黄芩、石膏、竹
茹。饮食而硬塞呕者，此咽中作痛闭塞而呕也，加味大力子汤。甘草、射干、豆根、
荆芥、防风、陈皮、连翘、苦参、大力、桔梗。
心肝火旺，相戈而鸣，又有胃热则切牙，肝热则寒战。肺热而切牙者治宜清解散。切牙者，乃足阳明胃经
主之，阳明主肌肉，其经走于上下齿龈，邪并阳明，故切牙且胃热，非石膏不为
功，黄芩次之。《经》云∶毒火深藏肾与肝，升沉二脏扰何安，
齿牙相戈声何惨，透解潜藏自贴然。此痘疹兼论。
火毒在肝，肝则藏血而养筋。毒在肾，肾则主骨而生肝还以养血。犹唇齿之邦，两受其虐而失其和，齿其
妄剧而自斗矣，但虚者则声松，实者声紧，痘疹皆同。
心经之症，邪毒蕴结于心，心主声言，心神安则声言自清。邪热在内，心神不安，故谵语，宜升解散少加
小草、石蒲、木通治之。狂言宜退火，痫声宜安神。
自汗者腠理流通，蕴毒发越，《经》云∶液汗通。皮润。又云∶毒从汗泄，不必止之。若汗出如淋者，
火炽极也。火扰于内，而汗涌于外，是汗为火逼可知。宜用桂枝合清火主之。
回后有此汗者，是余毒无所容，以汗而解也。验其人因汗而适快者是也，不宜再服收敛等药。
论汗者，血之液也。肾液从毛窍出者为汗，是汗亦血也。原其本，在肺之通调四布而得润乎一身，以滋
养四体，犹曰白露下降，草木敷荣可知。藏则存而为液，疏则泄而为汗，涸则皮毛枯涩，郁则肢体浮肿，
寒则凝，热则沸，血一枯则汗亦因而枯也，必矣。
口是脾的外窍，因脾热炽盛而导致口腔溃烂。另外，火邪侵犯心肺，心火亢盛，肺金受火克制，也会引起口腔溃烂，适宜用双解散为主方治疗，待痘疹回靥后重用生石膏。
肝主怒，肺主发声，毒邪结聚在肺肝之中，所以患者烦躁啼哭且声音不绝，通过泻火即可痊愈。
肝和肺中有毒邪，且毒气冲犯胃部，肺和胃受到内毒侵袭，所以出现干呕。
冲脉和任脉的火气上犯清窍，导致干呕无物，这是脏腑内部受损的表现。如果是进食后呕吐，这属于热性呕吐，适宜使用陈皮、黄芩、石膏、竹茹。如果饮食吞咽困难并引发呕吐，这是因为咽喉疼痛闭塞而导致的呕吐，适宜使用加味大力子汤（药物组成：甘草、射干、豆根、荆芥、防风、陈皮、连翘、苦参、牛蒡子、桔梗）。
心和肝火旺，相互刑克而发出声响；若有胃热则会出现磨牙，肝热则会出现寒战。肺热导致的磨牙，治疗适宜用清解散。磨牙这一症状，是由足阳明胃经所主，阳明经主管肌肉，其经脉行走于上下齿龈之间，邪气并入阳明经，所以出现磨牙且伴有胃热，非石膏不能奏效，黄芩次之。《内经》说：“毒火深藏于肾与肝，升沉二脏受扰如何安宁，牙齿相磨之声何等凄惨，透解潜藏之火自然贴服平静。”这是关于痘疹的综合论述。
火毒在肝，肝则贮藏血液以滋养筋脉。毒在肾，肾则主管骨骼并生髓，进而滋养肝血以养血。这就好比唇与齿的关系，两者共同遭受毒邪侵害而失去和谐，牙齿就会妄动剧烈而互相撞击。但是虚证的声音松弛，实证的声音紧促，痘疹病症中都是相同的道理。
心经的症状，是邪毒蕴结在心，心主声音言语，心神安宁则声音言语自然清晰。邪热在内，心神不安，所以出现胡言乱语，适宜用升解散少加小草、石菖蒲、木通来治疗。狂言适宜用退火法，痫病发出的声音适宜用安神法。
自汗是因为腠理通畅，蕴藏的毒邪向外发散，《内经》说：“津液通调则皮肤润泽。”又说：“毒邪随汗液排出，不必强行止汗。”如果出汗如淋雨般多，这是火气极盛的表现。火气扰乱于内，而汗液涌出於外，可知这是汗被火气逼迫所致。适宜用桂枝合清火方治疗。痘疹回靥后出现这种汗出的情况，是余毒无处容身，随汗液而解的表现。验证方法是看其人是否因出汗而感到舒适，这种情况不宜再服用收敛类药物。
论及汗，它是血的津液。肾中的津液从毛孔排出就成为汗，所以汗也是血的一种表现。追溯其本源，在于肺的通调功能散布全身从而滋润身体，以滋养四肢百骸，就像白露下降，草木繁茂一样可以知晓。津液在体内储存则为液，疏泄于体外则为汗，枯竭则皮毛枯涩，郁滞则肢体浮肿，寒冷则凝结，炎热则沸腾，血一旦枯竭，汗也必然随之枯竭。
The mouth is the external orifice of the Spleen; oral ulceration (taokou) occurs due to excessive heat in the Spleen. Additionally, when fire pathogens invade the Heart and Lungs, excessive Heart Fire causes Metal (Lung) to be controlled by Fire, also leading to oral ulceration. The primary formula for treatment is Shuangjie San (Double-Resolution Decoction), with heavy use of Shigao (Gypsum Fibrosum) after the eruption subsides.
The Liver governs anger, and the Lung governs vocalization. When toxins accumulate within the Lung and Liver, the patient becomes irritable and cries incessantly. This condition resolves through purging fire.
When toxins reside in the Liver and Lung and surge into the Stomach, causing internal toxicity in these organs, dry retching (gan'ou) occurs.
If fire from the Chong and Ren meridians invades the clear pathways upward, resulting in dry retching without vomitus, this indicates internal injury to the Zang-Fu organs. If vomiting occurs after eating, it is classified as heat-induced vomiting, treated with Chenpi (Citri Reticulatae Pericarpium), Huangqin (Scutellariae Radix), Shigao (Gypsum Fibrosum), and Zhuru (Bambusae Caulis in Taenia). If swallowing difficulties lead to vomiting due to pain and obstruction in the throat, Jiawei Dalizi Tang (Modified Burdock Seed Decoction) is indicated. Its ingredients include Gancao (Glycyrrhizae Radix et Rhizoma), Shegan (Belamcandae Rhizoma), Dougen (Derridis Radix), Jingjie (Schizonepetae Herba), Fangfeng (Saposhnikoviae Radix), Chenpi (Citri Reticulatae Pericarpium), Lianqiao (Forsythiae Fructus), Kushen (Sophorae Flavescentis Radix), Dalizi (Arctii Fructus), and Jiegeng (Platycodonis Radix).
Excessive fire in the Heart and Liver causes mutual aggression and noise; gastric heat leads to teeth grinding (qiya), while liver heat causes chills. For teeth grinding caused by lung heat, Qingjie San (Clear-Resolution Decoction) is appropriate. Teeth grinding is governed by the Foot-Yangming Stomach Meridian. The Yangming meridian governs muscles and runs along the upper and lower gingiva. When pathogens merge with the Yangming meridian, teeth grinding accompanied by gastric heat occurs. Only Shigao (Gypsum Fibrosum) can effectively address this, with Huangqin (Scutellariae Radix) being secondary. The Classic states: "Toxic fire hides deep in the Kidney and Liver; how can the ascending and descending organs remain peaceful? How tragic is the sound of grinding teeth! Resolving the hidden fire brings natural calm." This discusses varicella/smallpox conditions comprehensively.
Fire toxins in the Liver affect its function of storing blood and nourishing sinews. Toxins in the Kidney affect its function of governing bones and generating marrow, which subsequently nourishes Liver blood. Like lips and teeth, both suffer under toxin attack and lose harmony, causing teeth to grind violently. However, deficiency patterns present with loose sounds, while excess patterns present with tight sounds; this applies to all smallpox/varicella cases.
Symptoms of the Heart Meridian involve toxic accumulation in the Heart. Since the Heart governs speech, a tranquil Spirit results in clear speech. Internal pathogenic heat disturbs the Spirit, causing delirious speech (shanyu). Treatment involves Shengjie San (Ascending-Resolution Decoction) with minor additions of Xiaocao (Polygoni Avicularis Herba), Shipu (Acori Tatarinowii Rhizoma), and Mutong (Akebiae Caulis). Delirious speech requires fire-reducing methods, while sounds associated with epilepsy require spirit-calming methods.
Spontaneous sweating (zihan) indicates open pores and the venting of accumulated toxins. The Classic states: "Fluids flow freely, skin remains moist." It also says: "Toxins are expelled via sweat; there is no need to stop it forcibly." However, profuse sweating like pouring rain indicates extreme fire intensity. Internal fire disturbance forces sweat outward, proving that sweat is compelled by fire. Treatment uses Guizhi Tang (Cinnamon Twig Decoction) combined with fire-clearing agents. Sweating after the eruption subsides indicates residual toxins finding release through sweat. Verification lies in whether the patient feels comfortable after sweating; in such cases, astringent medicines should not be administered again.
Regarding sweat: it is the fluid of Blood. Fluids from the Kidney exiting through hair follicles become sweat; thus, sweat is related to Blood. Tracing its origin, the Lung's regulating and dispersing functions distribute fluids to moisten the body and nourish the limbs, akin to white dew descending and promoting lush vegetation. Stored internally, it is fluid; discharged externally, it is sweat. Depletion leads to dry skin; stagnation leads to edema. Cold causes coagulation; heat causes boiling. If Blood dries up, Sweat inevitably follows.