岭南一大商病疟胸中痞闷烦躁昏不知人愿得凉药清利上膈其症上热下寒脉沉而微以生姜
附
子作汤浸冷俾服超时苏醒自言胸膈疏爽然不知实用附子也若庸工见其胸中痞闷投以凉药下之
十无一生然此法惟山岚瘴气所致下体虚冷之人宜施若暑疟痰疟则别处治可也
吴中王省 遇仙丹治风淫末疾而四肢为四末也脾主四肢风邪客于肝则淫脾脾为肝克故疾
在末若风寒湿痹而气滞不行或麻木作痛手足不仁此为有余之症法当行气胜湿服此丹有功若痿痹
之
症得之血虚所致认作有余而治去生不远或有问余曰此方纯阳真人所授何西北之人服者多效东
南之人服者几危其理殆不可晓余曰西北水深土浓禀气盛是以乌附姜桂之剂可以胜之脾恶湿得
燥则愈南方禀气弱木动火明阳气易升投之为害甚矣故曰天有四时寒暑迭用地有五方高下随宜
此之谓欤
成化丁酉年七月间钦天监张台官景芳领朝命往陕西秦邸兴平王治HT 张至半途偶获腹胀之
症医
莫能疗寓居卧龙寺待尽而已抵夜见 眉一叟忽过访自云能治此疾张延诊视两手脉即口授一方
以杏仁陈皮海螵蛸等分为细末佐以 树叶槐树叶桃树枝各七件翌日正午时汲水五桶煎三四沸
至星止时再煎一沸患者就浴令壮人以手汤中按摩脐之上下百数少时转矢气病即退矣张领教一
如
其法黎明此老复至病去十之七八矣酬以礼物纤毫不受是夕肿胀平复此老更不复见矣或谓张景
芳遇仙云(客座新闻)
岭南地区有一位大商人患疟疾，感到胸中痞闷、烦躁不安，甚至昏迷不省人事。他希望能得到凉性药物来清利上焦膈部。然而他的症状表现为上热下寒，脉象沉而微弱。医生用生姜和附子煎煮成汤剂，冷却后让他服用。服完后不久，患者苏醒过来，自述胸膈部位舒畅清爽，但他自己并不知道实际上使用的是附子这味药。如果是一般庸医见到他胸中痞闷，就投以凉药攻下，这样的病人十有八九无法存活。然而这种方法只适用于因山岚瘴气所致、且下体虚冷的患者才适宜施用；如果是暑疟或痰疟，则应另外施治。
吴中的王省使用“遇仙丹”治疗风邪引起的四肢疾病。因为四肢被称为“四末”，脾主四肢，风邪客居于肝则会侵犯脾脏（木克土），所以病症表现在四肢末端。如果是风寒湿痹导致的气滞不行，或者出现麻木疼痛、手足不知痛痒的症状，这属于实证（有余之症），治疗方法应当行气胜湿，服用此丹会有功效。如果是痿痹之症，多由血虚引起，若误认为是实证而按实证治疗，离死亡就不远了。有人问我：这个方子是纯阳真人传授的，为什么西北地区的人服用大多有效，而东南地区的人服用却几乎造成危险？其中的道理大概难以理解。我回答说：西北地区水深土厚，人的禀赋之气旺盛，所以乌头、附子、干姜、肉桂等温热药剂可以胜任并治愈疾病。脾脏厌恶湿气，得到燥热之气则痊愈。南方人禀赋之气较弱，木气易动，火气易明，阳气容易升发，此时投以温热药物危害很大。所以说，天有四时变化，寒暑交替；地有五方差异，高低不同，用药需因地制宜，说的就是这个道理吧。
成化丁酉年（1477年）七月间，钦天监的天官张景芳奉朝廷命令前往陕西秦王府兴平王处办事。张景芳走到半路，偶然患上了腹胀的病证，医生们都无法治疗。他寄住在卧龙寺，等待死亡罢了。到了夜晚，一位长着长眉的老者忽然来访，自称能治好这种病。张景芳请老者诊视，老者把了两手脉后，口头传授了一个方子：用杏仁、陈皮、海螵蛸各等分研成细末，佐以桑树叶、槐树叶、桃树枝各七件。第二天正午时分，汲水五桶，煎煮三四沸，直到星星出现时再煎一沸。让患者在热水中沐浴，让壮汉用手在汤水中按摩患者脐部上下数百次。过了一会儿，患者放屁，病随即消退。张景芳完全按照这个方法去做。黎明时分，那位老人又出现了，此时病痛去除了十分之七八。张景芳赠送礼物酬谢，老人一丝一毫都不接受。当晚，肿胀完全平复，这位老人再也不见踪影了。有人说这是张景芳遇仙的故事。（出自《客座新闻》）
In the Lingnan region, a wealthy merchant suffered from malaria, experiencing chest fullness and oppression, irritability, and unconsciousness. He desired cool-natured medicines to clear and drain the upper jiao (upper burner). However, his symptoms presented as heat above and cold below, with a deep and faint pulse. The physician prepared a decoction of Shengjiang (Zingiberis Rhizoma) and Fuzi (Aconiti Lateralis Radix Praeparata), cooled it, and administered it. After taking it, the patient soon regained consciousness, reporting that his chest and diaphragm felt open and comfortable, though he was unaware that Fuzi had actually been used. If mediocre physicians, seeing his chest fullness, were to administer cool medicines to purge downwards, ten out of ten would likely die. Nevertheless, this method is only suitable for patients suffering from mountain miasma who have deficiency-cold in the lower body; for cases of summerheat malaria or phlegm-malaria, different treatments should be applied.
Wang Sheng from Wuzhong used "Yuxian Dan" (Immortal-Encounter Pill) to treat limb diseases caused by wind pathogenic factors. Since the four limbs are referred to as the "four extremities," and the Spleen governs the limbs, when wind pathogens lodge in the Liver, they overact on the Spleen (Wood overacting on Earth); thus, the disease manifests in the extremities. In cases of Bi syndrome caused by wind-cold-dampness leading to qi stagnation and obstruction, or presenting with numbness, pain, and insensitivity of the hands and feet, these are excess syndromes (syndromes of surplus). The treatment principle should be to promote qi circulation and overcome dampness, and taking this pill will yield merit. However, Wei-Bi (flaccidity and obstruction) syndromes often result from blood deficiency; if mistaken for excess and treated accordingly, death is not far off. Someone asked me: This formula was transmitted by Chunyang Zhenren (Pure Yang True Person). Why does it work well for people in the Northwest but nearly endanger those in the Southeast? The rationale seems inexplicable. I replied: In the Northwest, waters are deep and soils thick; people possess robust constitutional qi. Therefore, warm and hot agents such as Wutou (Aconiti Radix), Fuzi, Ganjiang (Zingiberis Rhizoma), and Rougui (Cinnamomi Cortex) can effectively treat their conditions. The Spleen dislikes dampness and recovers upon receiving dryness/heat. People in the South have weaker constitutions; Wood qi moves easily, Fire qi shines brightly, and yang qi ascends readily. Administering such [warm/hot] agents there causes great harm. Thus it is said: Heaven has four seasons, alternating cold and heat; Earth has five directions, varying in elevation. Medication must suit the locality—this is what is meant.
In July of the Dingyou year of the Chenghua era (1477), Zhang Jingfang, an astronomer official from the Imperial Astronomical Bureau, led a mission to Xingping Prince's residence in Shaanxi. On the way, Zhang suddenly developed abdominal distension, which physicians could not cure. He lodged at Wolong Temple, awaiting death. At night, an old man with long eyebrows visited him unexpectedly, claiming he could cure this ailment. Zhang invited him to examine his pulse. After palpating both wrists, the old man orally prescribed a formula: equal parts of Xingren (Armeniacae Semen Amarum), Chenpi (Citri Reticulatae Pericarpium), and Haipiaoxiao (Sepiae Endoconcha) ground into fine powder, supplemented with seven leaves each of Sangye (Mori Folium), Huaishu Ye (Sophorae Tonkinensis Folium), and Taozhi (Persicae Ramulus). The next day at noon, five buckets of water were drawn and boiled for three or four boils, then boiled once more when stars appeared. The patient took a bath in this water, while strong men massaged the area above and below his umbilicus hundreds of times in the water. After a short while, the patient passed flatus, and the illness subsided. Zhang followed the instructions exactly. At dawn, the old man reappeared; by then, seventy to eighty percent of the illness had vanished. Zhang offered gifts in gratitude, but the old man refused even a hair's breadth. That night, the swelling completely resolved, and the old man never appeared again. Some say this story concerns Zhang Jingfang meeting an immortal. (From *Kezuo Xinwen*)