冷热不调，饮食不节，使人阴阳清浊之气相干，而变乱于肠胃之间，则成霍乱。霍乱而
大吐下后，其肠胃俱虚，乃至汗出，其脉欲绝，手足皆冷，名为四逆。四逆者，谓阴阳卒厥
绝也。
冷热不调，饮食不节，使人阴阳清浊之气相干，而变乱于肠胃之间，则成霍乱。霍乱而
转筋者，由冷气入于筋故也。足之三阴三阳之筋起于人足指，手之三阴三阳之筋，起于手指
，并循络于身。夫霍乱大吐下之后，阴阳俱虚，其血气虚极，则手足逆冷，而荣卫不理，冷
搏于筋，则筋为之转。冷入于足之三阴三阳，则脚筋转；入于手之三阴三阳，则手筋转。随
冷所入之筋，筋则转。转者，皆由邪冷之气击动其筋而移转也。
冷热不调，饮食不节，使人阴阳清浊之气相干，而变乱于肠胃之间，则成霍乱。而云中
恶者，谓鬼气卒中于人也。其状卒然心腹绞痛，而客邪内击，与饮食、寒冷相搏，致阴阳之
气亦相干乱，肠胃虚，则变吐利烦毒，为中恶霍乱也。
霍乱之病，由冷热不调，饮食不节，阴阳错乱，清浊之气相干在肠胃之间。发则心腹绞
痛吐利。腑脏虚弱，或烦，或渴，或呕哕，或手足冷，或本挟宿疹，今因虚而发也。
冷热不调，饮食不节，使人阴阳清浊之气相干，而变乱于肠胃之间，则成霍乱。而霍乱
之后，荣卫未和调，腑脏尚虚冷，或吐痢不止，呕逆未定，或宿疹乘虚而发，更生诸病也。
冷热失调，饮食无度，导致人体阴阳清浊之气相互干扰，在肠胃之间发生紊乱，从而形成霍乱。霍乱患者在剧烈呕吐和腹泻之后，肠胃功能极度虚弱，甚至出现出汗、脉搏微弱欲绝、四肢冰冷等症状，这被称为“四逆”。“四逆”是指阴阳之气突然厥逆断绝。
若霍乱患者出现肢体抽搐（转筋），是因为寒气侵入筋脉所致。足部的三条阴经和三条阳经的筋脉起于足趾，手部的三条阴经和三条阳经的筋脉起于手指，它们都沿着经络循行分布于全身。霍乱患者在剧烈呕吐和腹泻后，阴阳两虚，气血极度亏虚，导致手足逆冷，营卫之气运行不畅，寒气与筋脉相搏结，致使筋脉发生抽搐。寒气侵入足部三阴三阳经的筋脉，则脚部筋脉抽搐；侵入手部三阴三阳经的筋脉，则手部筋脉抽搐。寒气侵入哪条筋脉，哪条筋脉就会发生抽搐。所谓“转筋”，都是因为邪寒之气冲击并扰动筋脉，使其位置移动而发生抽搐。
若霍乱发作时伴有“中恶”症状，是指鬼气（此处指突发的强烈致病邪气）突然袭击人体。其表现为突然的心腹剧烈绞痛，外来邪气在内冲击，与体内的饮食停滞、寒气相互搏结，导致阴阳之气进一步混乱，肠胃空虚，从而引发呕吐、腹泻、烦躁及毒热症状，这称为“中恶霍乱”。
霍乱这一疾病，是由于冷热失调、饮食不节，导致阴阳错乱，清浊之气在肠胃之间相互干扰。发病时会出现心腹剧烈绞痛、呕吐和腹泻。由于脏腑虚弱，可能伴有烦躁、口渴、干呕呃逆、手足冰冷等症状；或者原本就有旧疾，如今因身体虚弱而诱发。
霍乱病之后，如果营卫之气尚未调和，脏腑仍然虚冷，可能会出现呕吐腹泻不止、恶心呕吐未平息，或者旧疾乘虚复发，从而产生其他各种病症。
Disharmony of cold and heat, and irregular diet, cause the Qi of Yin-Yang, clear and turbid to interfere with each other, leading to disorder between the intestines and stomach, resulting in Huoluan (cholera-like syndrome). After severe vomiting and purging in Huoluan, the intestines and stomach become deficient, potentially leading to sweating, a pulse that is faint and nearly imperceptible, and coldness of the hands and feet; this condition is named "Sini" (Four Coldness/Reversal of Extremities). "Sini" refers to the sudden jue-ni (reversal) and interruption of Yin-Yang Qi.
If Huoluan is accompanied by muscle cramps (Zhuanjin), it is due to cold Qi entering the sinews. The sinews of the three Yin and three Yang meridians of the foot originate from the toes, and those of the hand originate from the fingers, all circulating through the body via the collaterals. After severe vomiting and purging in Huoluan, both Yin and Yang are deficient, and Blood and Qi are extremely depleted, causing coldness of the extremities and disordered Ying-Wei (Nutritive and Defensive) Qi. When cold attacks the sinews, they undergo cramping. If cold enters the sinews of the foot's three Yin and three Yang meridians, the leg sinews cramp; if it enters the hand's three Yin and three Yang meridians, the arm sinews cramp. Whichever sinew the cold enters becomes cramped. Cramping occurs because pathogenic cold Qi strikes and agitates the sinews, causing them to shift and spasm.
If Huoluan presents with "Zhong'e" (sudden attack by malevolent Qi), it refers to sudden invasion by ghostly Qi (pathogenic factors). The presentation involves sudden, severe colicky pain in the heart and abdomen, where external pathogenic Qi strikes internally, combing with retained food and cold, further disrupting Yin-Yang Qi. With deficient intestines and stomach, this leads to vomiting, diarrhea, irritability, and toxic heat, termed "Zhong'e Huoluan."
The disease of Huoluan arises from disharmony of cold and heat and irregular diet, causing disorder of Yin-Yang and interference of clear and turbid Qi within the intestines and stomach. Upon onset, there is severe colicky pain in the heart and abdomen, vomiting, and diarrhea. Due to deficiency of the fu and zang organs, symptoms may include irritability, thirst, retching or hiccups, coldness of the hands and feet, or the recurrence of chronic conditions triggered by current deficiency.
After Huoluan, if Ying-Wei Qi remains unharmonized and the fu and zang organs remain deficient and cold, one may experience persistent vomiting and diarrhea, unresolved nausea and vomiting, or the reactivation of chronic diseases due to deficiency, giving rise to various other ailments.