素问曰。人之伤于寒也。则为病热。热虽甚不死。其两感于寒而
病者。必不免于死。
又曰。两感于寒者。病一日。则巨阳与少阴俱病。则头痛口干。
烦满而渴。二日。则阳明与太阴俱病。则腹满身热。不饮食。谵语。三
日。少阳与厥阴俱病。则耳聋囊缩而厥。水浆不入。不知人。六日死。
病源曰。水浆不入。不知人。则六日而死。其义甚明。
问曰。素问言不知人。六日死。又言三日其气乃尽。何也。雍曰。
两感之病。表里俱传。三日而六经竟。虽竟而气未绝。故经竟之后。
又三日。其气乃绝。其言三日者。谓三日而阳明之气方尽故也。言六
日者。通传经之日也。传经三日。气尽故言六日。何以明之。三日经
竟之时。五脏已伤。六腑不通。营卫不行。如是之后。又三日。气尽乃
死。帝以疑而问之。而岐伯告以阳明气血盛不知人。三日而后死也。
经既曰如是之后。则是传六经竟之后也。又曰不知人。三日。则是阳
明未绝之时也。经竟甚明。而或者谓其传六经而后死。夫能再传。则
不死矣。本以邪气传至少阳欲传太阴之间。而太阴已先与阳明同受
邪气。不能更受后来再传之邪。虽太阴复欲以邪传之三阳。而三阳
邪气亦皆满。亦不更尔容受。两邪相拒。六经皆满。俱不能流注传
泄。是以六腑不通。营卫不行。水浆不入。不知人。以待阳明之气尽
而后死矣。阳明。胃经也。胃为血气之海。朝夕灌注营卫六腑十二经
者。皆胃之气血也。诸经虽绝。独阳明气血未尽。故又三日而后死
也。六日死。三日死。只是两感一证。或者谓再传为六日死。邪气直
入阳明。为三日死。遂分两证。此说甚误。未通经意。又不当改经血
气盛为邪气盛。仍有血气随邪而尽之说。皆失也。反复读经。当自得
之。庞氏曰。两感之疾。素问无脉候。今详之。凡脉沉者。皆属阴也。
一日脉当沉而大。沉者。少阴也。大者。太阳也。二日脉当沉而长。三
日脉当沉而弦。乃以合表里之脉。沉长弦皆隐于沉大也。凡三阴无
合病。惟三阳有合病。今三阳与三阴合病。故其脉似沉紧而大。似沉
实而长。亦类革至之死脉也。
王仲弓监丞曰。本论言两感俱作。治有先后。发表攻里。本自不
同。近时张翊云。论有伤寒。医下之。利不止。身疼痛者。急当救里。
后身疼痛清便自调者。急当救表。今可根据仿而治。既云治有先后。则
宜先救里。内才温则可医。然救表亦不可缓也。朱氏曰。内尤为急
也。雍曰。救里药用四逆。救表药用桂枝汤。此法出于不得已。犹愈
于束手待毙矣。仲景曰。救里药用四逆。救表药用桂枝汤。更看临时
寒热多少参订之。幸有表里一轻者。则急治其重者也。然其治大宜
速。过三日。则水浆不入。虽有药不纳已。张亦未悟此也。
两感论曰。病患有不治之证。古人不复论方药者。立论固可如
此。医家亦可如此。而人有父兄母弟至亲。不幸遇疾如此。能坐视不
思拯援万死一生之术哉。孙真人论。精神困者。病久不瘥。欲死者。
但与药救之。十人中或瘥三四。以是言。则人虽有不治之病。其气未
绝之间。亦无不服药待尽之理。今观两感之证。以阴阳之经。邪气皆
满。不相来往传注。故为必死之候。乘其三日内邪气未满。营卫可通
之时。早为疗治。尚或不死。若六经邪气三日既满。则水浆不入。汤
药何缘可纳。势须于初觉之时急治之。然初感之日。谁能断然不疑。
知其为两感。拟议之间。已不及矣。是以必至于死也。雍谓汤药至
此。不如针灸。汤药虽可内攻。而内攻未必至。虽至而药病方有胜
负。针艾可以外泄。随其轻重。必有泄而出者。昔虢太子之死。扁鹊
治之。盖外泄之术也。方其厥气上行。绝阳破阴。有甚于两感不知人
之证。扁鹊以为阳脉下坠。阴脉上争。令气闭而不通。夫厥气。亦邪
气也。阳脉阴脉者。即阳经阴经也。阳脉下坠。犹传之阳也。阴脉上
争。相搏而不能受也。气闭不通。以阴阳俱邪实。故不通。不通则水
浆不入矣。越人于是不施汤剂。而遽用针石。外取三阳五会。有间。
太子苏。是知汤不能达于外。而针尚可泄于外也。既苏而得为五分
之熨以逐余邪。邪去然后得服汤药。二旬而复故。倘使汤先。必不能
得入。何缘有复苏之理。今两感之邪。与尸厥之邪。其暴杀人一也。
诚能效越人先针后汤之术。取之三阳。使三阳气缓。然后灼三阴之
会以泄其邪。邪气未尽。方以汤攻。使无所逃。既尽。则以汤养之。虽
生死未可必。而其为治。有所据而不谬矣。故愚意欲先取昆仑委中。
乃去其血以泄太阳。次取三里以泄阳明。后取邱墟阳陵泉。以泄少
阳。三阳气既缓。急灸三阴交穴。以泄三阴之邪。此穴亦难取。或上
下左右少差即能中。一阴二阴不中。必三阴俱中。仍须审度。再分
灸之。上阴陵泉可泄太阴。太溪可泄少阴。大敦可泄厥阴。炷如麦
粒。缓缓灸之。徐泄其气。不必以多为贵也。虽其如此。亦不可以不
灸三阴交。先并泄之。然后分得阴阳。得阴阳缓。乃可服汤。泄不患
多。治不厌速。盖有三日之期。不可待也。所以不敢用熨者。必为火
邪。故惟用汤。二者。皆阴气闭不通之疾。大略相似。而其为寒热则
异也。以是思之。则三阴合病之中。脉有负者。亦宜灸刺以治之。且
如阳明少阳合病。其脉负者。少阳木气盛也。泻邱墟阳陵泉。则少阳
木气不得不平。补三里。则阳明之土。不得不旺。或不精补泻者。第
以刺为泻。灸为补。古人皆有是法。如是。则虽死亦有可生理。所谓
十中三四愈者。未必不如孙氏之言也。虽然。天下之事。固有大小同
异。而其理一也。昔洪水横流。泛滥于中国。禹决九州。然后人得平
土而居之。愚因诵此。而得通病有外泄之理。使早得而熟之。则越人
氏之学。何难至之。颜渊曰。舜何人也。予何人也。有为者亦若是。况
卢扁乎。惜余得之暮年。所用之小也。然亦不敢不告诸来者。故备言
之。
The *Suwen* (Basic Questions) states: When humans are injured by cold pathogens, they develop febrile diseases. Even if the heat is severe, it will not result in death. However, for those who contract "Lianggan" (simultaneous contraction of exterior and interior meridians) from cold, death is inevitable.
It further states: In cases of Lianggan contracted from cold, on the first day, the Taiyang (Greater Yang) and Shaoyin (Lesser Yin) meridians are affected simultaneously, resulting in headache, dry mouth, vexation, fullness, and thirst. On the second day, the Yangming (Bright Yang) and Taiyin (Greater Yin) meridians are affected simultaneously, resulting in abdominal fullness, generalized fever, anorexia, and delirious speech. On the third day, the Shaoyang (Lesser Yang) and Jueyin (Terminal Yin) meridians are affected simultaneously, resulting in deafness, retraction of the scrotum, and cold extremities; the patient cannot take fluids or food and loses consciousness. Death occurs on the sixth day.
The *Bingyuan* (Source of Diseases) states: If the patient cannot take fluids or food and has lost consciousness, death will occur on the sixth day. The rationale is very clear.
A question arises: The *Suwen* states that loss of consciousness leads to death on the sixth day, yet it also says that "the qi exhausts after three days." What is the reason? Guo Yong replies: In Lianggan disease, the exterior and interior meridians transmit the pathogen simultaneously. After three days, the transmission through the six meridians is completed. Although the transmission process is complete, the vital qi has not yet completely exhausted. Therefore, three days after the completion of the meridian transmission, the qi finally exhausts. When it says "three days," it refers to the exhaustion of the Qi of the Yangming meridian at that time. When it says "six days," it refers to the total duration of the meridian transmission. The transmission takes three days, and the qi exhausts, hence the mention of the sixth day. How is this clarified? At the time when the six meridians' transmission completes on the third day, the five zang organs are already damaged, the six fu organs are obstructed, and the Ying (Nutritive) and Wei (Defensive) qi cease to circulate. After such a state persists for another three days, the qi exhausts and death ensues. The Yellow Emperor asked out of doubt, and Qibo answered that because the Qi and Blood of the Yangming meridian are abundant, the patient experiences loss of consciousness, and death occurs three days later. Since the text says "after such a state," it implies after the transmission through the six meridians is complete. It also says "loss of consciousness for three days," which indicates the period before the Yangming qi is completely exhausted. The process of meridian transmission is clear. However, some believe that death occurs after the transmission through the six meridians. If there were a second transmission, death would not occur. Originally, the pathogen transmits to the Shaoyang meridian and intends to transmit to the Taiyin meridian, but the Taiyin meridian has already received the pathogen simultaneously with the Yangming meridian and cannot accept subsequent transmitted pathogens. Although the Taiyin meridian might attempt to transmit the pathogen back to the Three Yang meridians, the pathogens in the Three Yang meridians are already full and cannot accommodate more. The two pathogens resist each other, filling all six meridians, preventing flow and discharge. Thus, the six fu organs are obstructed, the Ying and Wei qi do not circulate, fluids and food cannot be taken, and consciousness is lost, waiting only for the Qi of the Yangming meridian to exhaust before death. The Yangming meridian is the Stomach meridian. The Stomach is the sea of Qi and Blood; the Qi and Blood that nourish the Ying, Wei, six fu organs, and twelve meridians morning and evening are all derived from the Stomach. Although the Qi and Blood of all other meridians may be exhausted, the Qi and Blood of the Yangming meridian remain unexhausted, hence death occurs three days later. Whether stated as death on the sixth day or the third day, it refers to the single syndrome of Lianggan. Some argue that a second transmission causes death on the sixth day, while direct entry into Yangming causes death on the third day, thus dividing it into two syndromes. This view is erroneous, fails to understand the classic's intent, incorrectly changes "abundant Qi and Blood" to "abundant pathogen," and posits that "Qi and Blood exhaust along with the pathogen," all of which are mistakes. Repeatedly reading the classic will lead to natural understanding.
Pang Shi states: The *Suwen* does not record pulse diagnoses for Lianggan. Analyzing it now, any sinking pulse belongs to the Yin category. On the first day, the pulse should be sinking and large. Sinking represents Shaoyin; large represents Taiyang. On the second day, the pulse should be sinking and long. On the third day, the pulse should be sinking and wiry. These correspond to the exterior-interior pulse relationships. Sinking, long, and wiry pulses are all implicit within the sinking-large pulse. Generally, there are no combined diseases among the Three Yin meridians, only among the Three Yang meridians. Now, since the Three Yang and Three Yin meridians are involved in a combined disease, the pulse resembles sinking-tight and large, or sinking-solid and long, similar to the Ge (Leather) pulse or the Zhi (Arrival) pulse, which are signs of death.
Wang Zhonggong, Supervisor, states: The original treatise discusses Lianggan occurring simultaneously, with treatment having a sequence. Releasing the exterior and purging the interior are fundamentally different. Recently, Zhang Yi cited a case where a patient with Cold Damage was treated with purgatives, resulting in persistent diarrhea and body pain. In such cases, one should urgently rescue the interior. Later, when body pain ceases and bowel movements normalize, one should urgently rescue the exterior. One can follow this model for treatment. Since treatment has a sequence, rescuing the interior should come first. Only when the interior is warm can treatment proceed. However, rescuing the exterior should not be delayed. Zhu Shi states: Rescuing the interior is particularly urgent. Guo Yong states: For rescuing the interior, use Sini Tang (Four Reversal Decoction); for rescuing the exterior, use Guizhi Tang (Cinnamon Twig Decoction). This method is a last resort, but better than waiting passively for death. Zhang Zhongjing states: Use Sini Tang for rescuing the interior and Guizhi Tang for rescuing the exterior. Adjust based on the degree of cold and heat at the time. If both exterior and interior symptoms are mild, urgently treat the more severe one. However, treatment must be swift. After three days, the patient cannot take fluids; even if medicine is available, it cannot be retained. Zhang Yi did not grasp this point.
The *Treatise on Lianggan* states: There are syndromes considered incurable, so ancients did not discuss formulas for them. While theoretical discussion may proceed this way, physicians might adopt this attitude. However, when one's close relatives suffer from such diseases, how can one sit idly without seeking methods to save them from near-death situations? Sun Simiao stated that for patients with depleted spirit and prolonged illness nearing death, administering medicine might cure three or four out of ten. Thus, even for incurable diseases, while vital qi remains, there is no reason not to administer medicine until the end. Observing the Lianggan syndrome, the pathogens fill both Yin and Yang meridians, preventing mutual transmission, making it a fatal prognosis. If treated early, while within three days the pathogens have not fully filled the meridians and Ying-Wei circulation is still possible, survival might be achieved. However, if after three days the pathogens in all six meridians are full, the patient cannot take fluids, and how could decoctions enter? Urgent treatment is necessary at the initial stage. Yet, at the onset, who can definitively diagnose Lianggan without hesitation? By the time of deliberation, it is too late, leading inevitably to death. Guo Yong believes that at this stage, acupuncture and moxibustion are superior to herbal decoctions. Decoctions may not reach the target effectively, and even if they do, the outcome depends on the struggle between medicine and pathogen. Acupuncture and moxa can expel pathogens externally according to severity. In the case of the Crown Prince of Guo, Bian Que used external expulsion techniques. His condition involved upward-rushing Jue Qi (Rebellious Qi), severing Yang and breaking Yin, worse than the unconsciousness in Lianggan. Bian Que diagnosed descending Yang pulses and ascending Yin pulses, causing Qi blockage. Jue Qi is also a pathogen. Yang and Yin pulses refer to Yang and Yin meridians. Descending Yang pulses imply pathogen transmission to Yang meridians; ascending Yin pulses indicate conflict and inability to bear it. Qi blockage results from excess pathogens in both Yin and Yang meridians, leading to inability to take fluids. Bian Que did not use decoctions but immediately applied needles. He selected the San Yang Wu Hui (Three Yang Five Meetings) acupoint externally. After a while, the prince revived. This shows that decoctions cannot reach externally, whereas needles can expel externally. After revival, he used hot compresses (five fen thickness) to drive out residual pathogens. Once pathogens were cleared, decoctions were administered, and health returned in twenty days. Had decoctions been used first, they could not have entered, and revival would have been impossible. The sudden lethality of Lianggan pathogens is similar to that of Shijue (Corpse-like Coma) pathogens. If one could emulate Bian Que’s technique of needle first, then decoction, selecting points from the Three Yang meridians to缓 (slow/relax) their Qi, then burning intersection points of the Three Yin meridians to expel pathogens, and using decoctions only after pathogens are exhausted to nourish the body, although survival is not guaranteed, the treatment would be grounded and correct. My suggestion is to first select Kunlun (BL60) and Weizhong (BL40), bleed to expel Taiyang pathogens. Next, select Zusanli (ST36) to expel Yangming pathogens. Then, select Qiuxu (GB40) and Yanglingquan (GB34) to expel Shaoyang pathogens. Once the Three Yang Qi is relaxed, urgently moxa Sanyinjiao (SP6) to expel Three Yin pathogens. This point is difficult to locate accurately; slight deviation misses the point. All Three Yin meridians must be correctly targeted. Careful measurement is required. Subsequently, moxa Yinlingquan (SP9) above to expel Taiyin pathogens, Taixi (KI3) to expel Shaoyin pathogens, and Dazhuan (LR1) to expel Jueyin pathogens. Use wheat-grain-sized moxa cones, moxa slowly to gradually expel Qi; quantity is not as important as quality. Regardless, Sanyinjiao (SP6) must be moxa first to jointly expel, then balance Yin and Yang. Only when Yin-Yang Qi is relaxed can decoctions be taken. Expelling pathogens does not fear excess; treatment does not fear speed, as there is only a three-day window. I dare not use hot compresses due to the risk of Fire Pathogens, so I rely solely on decoctions. Both conditions involve blocked Yin Qi, sharing similarities but differing in cold/heat presentation. Considering this, in combined diseases of the Three Yin meridians with deficient pulses, moxa and acupuncture are also suitable. For example, in Yangming-Shaoyang combined disease with a deficient pulse, Shaoyang Wood Qi is excessive. Reducing Qiuxu and Yanglingquan calms Shaoyang Wood; tonifying Zusanli strengthens Yangming Earth. For those unfamiliar with tonification/reduction, using needle for reduction and moxa for tonification is an ancient method. Thus, even in fatal cases, there is hope for recovery, aligning with Sun Simiao’s statistic of 30-40% survival. Although matters vary in size and nature, the principle is one. Just as Yu the Great drained the floods to allow habitation, I realized that diseases can be treated via external expulsion. Had I mastered this earlier, Bian Que’s art would have been accessible. Yan Yuan said, "What kind of person was Shun? What kind of person am I? Those who act will be like him." How much more so for masters like Lu and Bian? I regret learning this in my twilight years, limiting its application, but I dare not withhold it from future generations. Hence, I state it fully.