发斑，下证未全，凉膈散（二十三）。未曾下，胃热发斑，白虎汤（二十二）加人参、白术。
阳明胃热发斑，脉沉须下者，三一承气汤（十三）下之。伤寒胃热发斑，凉膈散加滑石调五苓散（二十四）
甚妙。伤寒七、八日，发黄有斑，微热、腹满者，或痰实壅上，虽诸承气汤不过者，仲景曰∶寸脉浮滑
者可用瓜蒂散（二十六）吐之。
伤寒，发狂奔走，骂詈不避亲疏，此阳有余、阴不足，三一承气汤（十三）加当归、姜、枣名当
归承气汤，以利数行，候微缓以三圣散（二十七）吐之，后用凉膈散（二十三），黄连解毒汤（二十一）
调之。谵妄发狂，逾垣上屋，赴井投河，皆
为阳热极甚，用三一承气合解毒下之。惊悸癫狂，三一承气汤。发狂极甚，投河入井者，三下不过，
不可攻下，盒饭涌之，以瓜蒂散（二十六），吐出痰涎、宿物，一扫而愈，后以甘露饮（三十四）之类调之。
凡热病大汗将出而反寒战者，表之正气与邪气并甚于里，火热亢极而反兼水化制之，反为寒战，脉
微欲绝者，三一承气汤（十三）或十枣汤（三十一）下之。凡欲作汗，无问病之微甚，或已经新下者，或
下证未全者，但以凉膈散（二十三）调之；甚者黄连解毒汤（二十一）。或下后二、三日，或未经下，腹满
烦渴，脉沉实而有里证者，三一承气汤下之，势恶者加黄连解毒汤。或战不快者，或战后汗出
不快者，或战数次，经大战而汗不当者，乃并之太甚，而法之不达，通宜三一承
气汤，或更加黄连解毒汤下之，以解怫热而开郁结也。
Maculae (skin eruptions) occur when the indications for purgation are not yet complete; use Liangge San (Cooling the Diaphragm Powder). If no purgation has been performed previously, and maculae arise due to Stomach heat, add Ren Shen (Ginseng Radix et Rhizoma), Bai Zhu (Atractylodis Macrocephalae Rhizoma) to Baihu Tang (White Tiger Decoction).
For maculae caused by Yangming Stomach heat, if the pulse is deep and purgation is required, use Sanyi Chengqi Tang (Three-One Purging Decoction) to purge. For maculae in cold damage due to Stomach heat, Liangge San added with Hua Shi (Talcum) combined with Wuling San (Five-Ingredient Powder with Poria) regulates effectively. In cold damage lasting seven or eight days, with jaundice and maculae, slight fever, and abdominal fullness, or if phlegm-solidity obstructs the upper jiao and various Chengqi Decoctions fail, Zhang Zhongjing states: if the cun (inch) pulse is floating and slippery, Gouti San (Melon Seed Powder) may be used to induce vomiting.
In cold damage, manic running away, cursing without distinction between kin and stranger indicates excess Yang and deficient Yin. Use Sanyi Chengqi Tang (Three-One Purging Decoction) added with Dang Gui (Angelica Sinensis Radix), Sheng Jiang (Zingiberis Rhizoma Recens), Da Zao (Jujubae Fructus), named Danggui Chengqi Tang (Dang Gui Purging Decoction), to promote defecation several times. Wait until symptoms slightly ease, then use Sansheng San (Three-Sage Powder) to induce vomiting, followed by regulation with Liangge San (Cooling the Diaphragm Powder) and Huanglian Jiedu Tang (Coptis Decoction for Detoxification). Delirium and mania, such as climbing over walls, roofs, or jumping into wells and rivers, all result from extreme Yang heat. Use Sanyi Chengqi Tang combined with a detoxifying decoction to purge. Palpitations, epilepsy, and mania are treated with Sanyi Chengqi Tang. For extreme mania involving jumping into wells or rivers, if three purgations fail, do not continue purging; instead, induce vomiting using Gouti San (Melon Seed Powder) to expel phlegm-saliva and retained pathogenic factors, leading to immediate recovery, followed by regulation with Ganlu Yin (Sweet Dew Drink) or similar formulas.
In febrile diseases, if chills occur just before profuse sweating, it indicates that the healthy Qi on the exterior and the pathogenic factor are intensely conflicting within the interior. Extreme fire heat counteracts with water transformation, manifesting as chills. If the pulse is faint and nearly imperceptible, use Sanyi Chengqi Tang (Three-One Purging Decoction) or Shizao Tang (Ten-Jujube Decoction) to purge. For any case preparing to sweat, regardless of severity, whether recently purged or purgative indications are incomplete, regulate with Liangge San (Cooling the Diaphragm Powder); for severe cases, use Huanglian Jiedu Tang (Coptis Decoction for Detoxification). If two or three days after purgation, or without prior purgation, abdominal fullness, irritability, and thirst occur with a deep, solid pulse indicating interior syndrome, purge with Sanyi Chengqi Tang; for critical conditions, add Huanglian Jiedu Tang (Coptis Decoction for Detoxification). If shivering does not resolve, or sweating is inadequate post-shiver, or multiple shivers occur with abnormal sweating after intense conflict, this results from excessive conflict and ineffective therapeutic methods. Generally, use Sanyi Chengqi Tang, or add Huanglian Jiedu Tang (Coptis Decoction for Detoxification) to purge, thereby resolving constrained heat and opening stagnation.