〔《灵》〕黄帝曰∶夫百病者，多以旦慧、昼安、夕加、夜甚，何也？岐伯曰∶朝则人气
始生，病气衰，故旦慧。日中人气长，长则胜邪，故安。夕则人气始衰，邪气始生，故加。
夜半人气入脏，邪独居于身，故甚也。黄帝曰∶其时有反者，何也？岐伯曰∶是不应四时之
气，脏独主其病者，是必以脏气之所不胜时者，甚；以其所胜时者，起也。（《一日分为四
时篇》）
〔《素》〕肝主春，足厥阴少阳主治，其日甲乙。病在肝，愈于夏。夏不愈，甚于秋。秋
不死，持于冬。起于春，禁当风。肝病者，愈在丙丁。丙丁不愈，加于庚辛。庚辛不死，持
于壬癸，起于甲乙。肝病者，平旦慧，下晡甚，夜半静。心主夏，手少阴太阳主治，其日丙
丁。病在心，愈在长夏。长夏不愈，甚于冬。冬不死，持于春。起于夏，禁温食热衣。心病
者，愈在戊己。戊己不愈，加于壬癸。壬癸不死，持于甲乙，起于丙丁。心病者，日中慧，
夜半甚，平旦静。脾主长夏，足太阴、阳明主治，其日戊己。病在脾，愈在秋。秋不愈，甚
于春。春不死，持于夏。起于长夏，禁温食、饱食、湿地、濡衣。脾病者，愈在庚辛。庚辛
不愈，加于甲乙。甲乙不死，持于丙丁，起于戊己。脾病者，日 慧，日出甚，下晡静
。肺主秋，手太阴、阳明主治，其日庚辛。病在肺，愈在冬。冬不愈，甚于夏。夏不死，持
于长夏，起于秋，禁寒饮食寒衣。肺病者，愈在壬癸。壬癸不愈，加于丙丁。丙丁不死，持
于戊己，起于庚辛。肺病者，下晡慧，日中甚，夜半静。肾主冬，足少阴、太阳主治，其日
壬癸。病在肾，愈在春。春不愈，甚于长夏。长夏不死，持于秋。起于冬，禁犯 HT
热食，温炙衣。肾病者，愈在甲乙。甲乙不愈，甚于戊己。戊己不死，持于庚辛，起于壬
癸。肾病者，夜半慧，四季甚，不晡静。夫邪气之客于身也，以胜相加，至其所生而愈，至
其所不胜而甚，至其所生而持，自得其位而起，必先定五脏之脉，乃可言间甚之时，死生之
期也。（《脏气法时论》）
上以五脏时日占病愈甚极准，钱仲阳深得此理，学人究心而又扩充之。
〔《灵》〕病在脏，沉而大者，其病易已，小为逆。病在腑，浮而大者，其病易已。脉口
滑小紧以沉者，病益甚，在中。人迎气大紧以浮者，其病益甚，在外。脉口滑以沉者，病日
进，在内。人迎脉滑盛以浮者，病日进，在外。脉口浮滑者，病日进。人迎沉而滑者，病日
损。（《五色篇》）
[From *Ling Shu*] The Yellow Emperor said: Among various diseases, most manifest as lucidity in the morning, tranquility during the day, exacerbation in the evening, and severity at night. Why is this? Qibo replied: In the morning, the *Zhen Qi* (Upright Qi) begins to generate, and the pathogenic qi declines; therefore, there is lucidity in the morning. At noon, the *Zhen Qi* grows strong; when strong, it overcomes the evil; therefore, there is tranquility. In the evening, the *Zhen Qi* begins to decline, and the pathogenic qi begins to arise; therefore, there is exacerbation. At midnight, the *Zhen Qi* enters the Zang organs, leaving the pathogenic qi alone in the body; therefore, there is severity. The Yellow Emperor asked: What if there are cases contrary to this pattern? Qibo replied: This occurs when the condition does not follow the Qi of the Four Seasons, but is solely governed by the Zang organs. In such cases, the disease becomes severe during the time element that the Zang organ cannot overcome (Sheng); it improves during the time element that the Zang organ can overcome (Ke). (From "Chapter on Dividing One Day into Four Times")
[From *Su Wen*] The Liver governs Spring, with the Foot Jueyin (Liver) and Foot Shaoyang (Gallbladder) meridians taking charge, corresponding to the Jia and Yi days. When disease is in the Liver, it heals in Summer. If it does not heal in Summer, it exacerbates in Autumn. If it does not lead to death in Autumn, it stabilizes in Winter. It rises/recovers in Spring; wind exposure should be avoided. For Liver disease, recovery occurs on Bing and Ding days. If not recovered on Bing and Ding days, it exacerbates on Geng and Xin days. If it does not lead to death on Geng and Xin days, it stabilizes on Ren and Gui days, and rises/recovers on Jia and Yi days. Patients with Liver disease feel lucid at dawn, severe in the late afternoon, and quiet at midnight. The Heart governs Summer, with the Hand Shaoyin (Heart) and Hand Taiyang (Small Intestine) meridians taking charge, corresponding to the Bing and Ding days. When disease is in the Heart, it heals in Late Summer. If it does not heal in Late Summer, it exacerbates in Winter. If it does not lead to death in Winter, it stabilizes in Spring. It rises/recovers in Summer; warm food and hot clothing should be prohibited. For Heart disease, recovery occurs on Wu and Ji days. If not recovered on Wu and Ji days, it exacerbates on Ren and Gui days. If it does not lead to death on Ren and Gui days, it stabilizes on Jia and Yi days, and rises/recovers on Bing and Ding days. Patients with Heart disease feel lucid at noon, severe at midnight, and quiet at dawn. The Spleen governs Late Summer, with the Foot Taiyin (Spleen) and Foot Yangming (Stomach) meridians taking charge, corresponding to the Wu and Ji days. When disease is in the Spleen, it heals in Autumn. If it does not heal in Autumn, it exacerbates in Spring. If it does not lead to death in Spring, it stabilizes in Summer. It rises/recovers in Late Summer; warm food, overeating, damp places, and wet clothing should be prohibited. For Spleen disease, recovery occurs on Geng and Xin days. If not recovered on Geng and Xin days, it exacerbates on Jia and Yi days. If it does not lead to death on Jia and Yi days, it stabilizes on Bing and Ding days, and rises/recovers on Wu and Ji days. Patients with Spleen disease feel lucid during the day, severe at sunrise, and quiet in the late afternoon. The Lung governs Autumn, with the Hand Taiyin (Lung) and Hand Yangming (Large Intestine) meridians taking charge, corresponding to the Geng and Xin days. When disease is in the Lung, it heals in Winter. If it does not heal in Winter, it exacerbates in Summer. If it does not lead to death in Summer, it stabilizes in Late Summer, and rises/recovers in Autumn; cold food and cold clothing should be prohibited. For Lung disease, recovery occurs on Ren and Gui days. If not recovered on Ren and Gui days, it exacerbates on Bing and Ding days. If it does not lead to death on Bing and Ding days, it stabilizes on Wu and Ji days, and rises/recovers on Geng and Xin days. Patients with Lung disease feel lucid in the late afternoon, severe at noon, and quiet at midnight. The Kidney governs Winter, with the Foot Shaoyin (Kidney) and Foot Taiyang (Bladder) meridians taking charge, corresponding to the Ren and Gui days. When disease is in the Kidney, it heals in Spring. If it does not heal in Spring, it exacerbates in Late Summer. If it does not lead to death in Late Summer, it stabilizes in Autumn. It rises/recovers in Winter; hot food and clothes heated by moxibustion/fire should be avoided. For Kidney disease, recovery occurs on Jia and Yi days. If not recovered on Jia and Yi days, it exacerbates on Wu and Ji days. If it does not lead to death on Wu and Ji days, it stabilizes on Geng and Xin days, and rises/recovers on Ren and Gui days. Patients with Kidney disease feel lucid at midnight, severe at the end of each season (Chen, Xu, Chou, Wei), and quiet in the late afternoon. Generally, when pathogenic Qi invades the body, it acts according to the cycle of overcoming (Ke). It heals when reaching the generating (Sheng) phase, becomes severe when reaching the overcoming phase, stabilizes when reaching the generating phase again, and recovers when returning to its own position. One must first determine the pulse of the Five Zang organs to discuss the times of remission and exacerbation, as well as the periods of life and death. (From "Chapter on the Methods and Times of Zang Organs")
The above methods for predicting disease recovery and exacerbation based on the Five Zang organs and time/day are extremely accurate. Qian Zhongyang (Qian Yi) deeply understood this principle. Students of medicine should study it carefully and expand upon it.
[From *Ling Shu*] When the disease is in the Zang organs, a pulse that is deep and large indicates the disease will easily heal; a small pulse is adverse. When the disease is in the Fu organs, a pulse that is floating and large indicates the disease will easily heal. A Cun Kou (Radial artery) pulse that is slippery, small, tight, and deep indicates the disease is worsening, located internally. a Ren Ying (Carotid artery) pulse that is large, tight, and floating indicates the disease is worsening, located externally. A Cun Kou pulse that is slippery and deep indicates the disease is progressing daily, located internally. A Ren Ying pulse that is slippery, vigorous, and floating indicates the disease is progressing daily, located externally. A Cun Kou pulse that is floating and slippery indicates the disease is progressing daily. A Ren Ying pulse that is deep and slippery indicates the disease is diminishing daily. (From "Chapter on Five Colors")