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Warm disease refers to the condition where cold pathogenic factors latent in winter transform into heat, manifesting in spring. This is what is meant by "the yang qi of spring arises from the latent cold of winter." Wind-warmth is a warm disease complicated by new wind pathogenic factors. After inducing sweating, the wind pathogen is expelled, but the warmth pathogen emerges, resulting in burning heat of the body. Warm plague (Wenyi) occurs when warmth qi becomes excessive and forms pestilential qi. Damp-warmth involves warmth qi combined with dampness pathogen; dampness can generate warmth, and warmth can also generate dampness. Warm toxin refers to warmth qi that fails to dissipate rapidly, becoming stagnant and transforming into toxin, similar to Yang Toxin and Yin Toxin in Cold Damage diseases. Warm malaria is a warm disease where the pathogen resides in the Shaoyang channel, characterized by intermittent symptoms that come and go.

Spring-warmth syndromes vary in severity. If there is pre-existing latent cold from winter and a new contraction of spring wind, if the cold follows the wind and aggregates externally, the condition is mild; if the wind follows the cold and aggregates internally, the condition is severe. For aggregation internally, treat the interior without neglecting the exterior; for aggregation externally, treat the exterior without neglecting the interior. If the previously latent cold has already transformed into heat, and is further aggravated by spring wind, the interaction between wind and heat often results in wind-malaria. If the pathogen is guided outwards, it is mild; if stimulation causes the pathogen to sink deeper inward, it is critical. Additionally, individuals suffering from emotional disturbances, overeating, or fatigue who are re-exposed to the six climatic pathogens (wind, cold, summer-heat, dampness, dryness, fire): if the pathogen moves inward and the interior pathology is more severe than the exterior, treat the exterior first, then regulate the interior; if the pathogen moves outward and the exterior pathology is more severe than the interior, treat the interior first, then regulate the exterior. Wang Haogu stated: When treating the interior while considering the exterior, one must not use cold purgatives; otherwise, the exterior pathogen will sink into the interior. When treating the exterior while considering the interior, one must not use hot diaphoretics; otherwise, internal heat will be exacerbated on the exterior. He further stated: When the exterior is heavy and the interior is light, treat the exterior first, then the interior. In cases of accumulated cold injuring the cold, where the pulse indicates a Yin syndrome, even if there are superficial symptoms (biao), they need not be treated; only the interior needs treatment. Once the interior is warmed, the superficial symptoms will cease and heal spontaneously. Why? Because releasing-the-exterior herbs are rarely devoid of hot properties. Thus it is said: For Yin syndromes, treat the root (ben) without treating the branch (biao); both branch and root are preserved. Treating the branch without the root results in the loss of both.

When warmth pathogens emerge, yin fluids are inevitably injured first. If dispersing and resolving methods are indicated, yin-nourishing substances must be included. Ancient practitioners added child's urine to Cong Chi Tang (Scallion and Fermented Soybean Decoction) and added Rehmanniae Radix (Dihuang) and Ophiopogonis Radix (Maidong) to Zhi Chi Tang (Gardenia and Fermented Soybean Decoction), embodying this principle.

The macules caused by Warm Toxin differ from those in Cold Damage. The pathogen of Warm Toxin originates from the interior and manifests externally; the pathogen of Cold Damage enters from the exterior into the interior. Therefore, in Warm Toxin macules, the pathogen leaves the interior and moves toward the exterior, indicating a milder condition. In Cold Damage macules, the pathogen is excessive internally and manifests externally, indicating a severe condition. When the pathogen is excessive internally, it must be purged downward; this corresponds to Hua Yuanyuan's statement that "purging is necessary to prevent the pathogen from remaining in the stomach." When the pathogen moves toward the exterior, it can be released through the surface, corresponding to Guo Baiyun's statement that "the toxin has been stagnant for a long time before erupting; the disease is not in the interior, so purging is contraindicated. One must treat according to the exterior syndrome, using herbs to release muscle-layer heat."