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Indicated for Yin deficiency with hyperactive fire, pulmonary atrophy with hemoptysis, bone-steaming night sweats, and consumptive disease syndromes.
Huangbai (Phellodendri Cortex), stir-fried with salt wine; Zhimu (Anemarrhenae Rhizoma), stir-fried with salt water; each 4 liang. Shudi (Rehmanniae Radix Praeparata), steamed with wine; Biejiia (Testudinis Carapax et Plastrum), fried with su (rendered pork fat); each 6 liang. Mix with pig spinal cord and refined honey to make small pills, dried in the sun. Take 3 qian per dose, washed down with light salt water decoction.

[Annotation] Zhu Zhenheng stated: Yin is often insufficient, while Yang is often in excess. One should constantly nourish Yin so that Yin and Yang are balanced; then Water can control Fire, and thus no disease will occur. People nowadays indulge in desires frequently; once Jing (Essence) and Blood are depleted, Ministerial Fire (Xianghuo) must become hyperactive. True Yin becomes increasingly exhausted, and solitary Yang acts recklessly, causing all symptoms of consumptive disease (Laozai), tidal fever, night sweats, bone-steaming, cough, hemoptysis, and hematemesis to manifest. Therefore, among those suffering from these diseases due to hyperactive fire, eight or nine out of ten are affected; only two or three out of a hundred suffer from this due to deficient fire. Zhenheng elucidated the profound principles of the ancient sages that remained unexplored for a millennium; his merit is great! This formula can rapidly tonify True Yin and restrain Ministerial Fire, being more effective than Liuwei Dihuang Wan (Six-Ingredient Rehmannia Pill). Generally, using Liuwei Dihuang Wan to tonify Water at this stage cannot generate Water immediately; using Shengmai San (Generate Pulse Powder) to protect Metal may leave Lung Metal still dry. Only by urgently using the bitter property of Huangbai to firm the Kidney can Dragon Fire be controlled; subsequently, using the cooling property of Zhimu to cool the Lung can preserve injured Lung Metal. If one ignores the root, even if the illness leaves, recurrence is feared. Therefore, Shudi and Biejiia are used to greatly tonify Yin, which is called "cultivating the root and clearing the source." Although these symptoms exist, if there is poor appetite and loose stools, it indicates Spleen/Stomach deficiency, and this formula should not be used lightly.

Indicated for nocturnal emission, spermatorrhea, and "ghost intercourse" (hallucinatory sexual experiences due to mental disturbance).
Huangbai, Sharen (Amomi Fructus), Gancao (Glycyrrhizae Radix et Rhizoma). Grind into powder, mix with honey to make pills. Take 3 qian per dose.

[Collected Annotations] Zhao Yuhuang said: The Classic states: The Kidney governs Water and receives the Essence of the Five Zang and Six Fu organs to store it. It also states: The Kidney is the foundation of hibernation and sealing/storing, the residence of Essence. The Kidney is a solid organ, mostly deficient rather than excess. Since Liver Wood is the child of Kidney Water, it tends to drain the mother's Qi. Once Jueyin Fire moves, Essence flows out externally. Moreover, the Liver stores Hun (Ethereal Soul); if Hun and Shen (Spirit) are not contained, it is no wonder that night-time "ghost intercourse" and seminal emission occur. Fengsui Dan is an important herb for consolidating Essence. In this formula, Huangbai is the Sovereign herb because its flavor and nature are bitter and cold, capable of firming the Kidney. When Kidney function is firm, Yin Water need not fear flooding; Cold nature clears and purifies, preventing Dragon Fire from raging. When Water and Fire interact and contain each other, how can Essence fail to remain in its place? Gancao is added as an Assistant; Sweetness can relieve urgency, clear various Fires and internal disturbance of Liver Fire, and harmonize Water and Earth to achieve solid storage. As for Sharen, its pungent and warm nature enters the Kidney well. The Kidney dislikes dryness, and only Pungency can moisten it. Sharen unblocks the Triple Burner and promotes fluid distribution, allowing the Essence of the Five Zang and Six Fu to return to the Kidney. When Kidney Qi is stored, Marrow within the Kidney is naturally preserved. This takes inspiration from the meaning of "Fengsui" (Sealing Marrow). Wang Ang said: Adding Tiantong (Asparagi Radix), Dihuang (Rehmanniae Radix), and Renshen (Ginseng Radix) to this formula creates Santai Fengsui Dan. Tiantong tonifies Lung to generate Water; Dihuang tonifies Kidney to benefit Essence; Renshen tonifies Spleen to transform food into Essence. Because the herbs correspond to Heaven, Earth, and Man, and their tonifying effects cover Upper, Lower, and Middle Jiao, with Heaven and Earth establishing positions and Renshen assisting in the middle, it is called Santai (Three Capacities/Heaven-Earth-Man). Yu Chang said: Adding Huangbai enters the Kidney to nourish Yin; Sharen enters the Spleen to move stagnation; Gancao slightly modifies the bitterness of Tiantong and Huangbai, enabling them to jointly establish Middle Qi with Renshen, thereby extending the authority of Renshen. This is certainly not comparable to arbitrarily adding ingredients to existing formulas.