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[Verse] Leprosy (Mafen) generally results from the formation of toxic pestilential qi. Its etiology involves three aspects: damage to the five zang organs by wind, the appearance of five death signs indicating a true malignant prognosis, and the possibility of survival if treatment is adhered to strictly in the early stage.

[Note] This condition was formerly known as "Li Feng" (Leprosy/Pestilential Wind), which refers to wind pathogenic factors possessing toxicity. The Classics state: "Wind entering the vessels becomes Li." It also states: "In Li, Ying Qi (Nutritive Qi) is hot and corrupt, and its qi is not clear." Consequently, this leads to the collapse of the nasal bridge, deterioration of complexion, and ulceration of the skin. When toxic wind lodges in the vessels and does not depart, it is named Li Feng, now commonly called Leprosy (Da Ma Feng). There are three causes: first, it arises from local climatic and geographical conditions; it is rare in Central China but common in miasma-prone areas; second, it is contagious, occurring through contact with individuals suffering from leprosy, or transmission among parents, spouses, or family members, or due to lack of hygiene outdoors, or uncleanliness in latrines, houses, beds, bedding, or clothing; third, it results from improper self-care, such as bathing while exposed to cool air for temporary comfort, sleeping exposed to wind, or lying on damp ground, allowing toxic wind to invade the blood vessels. Although these causes have different names, they all belong to the pestilential qi of heaven and earth. After infection, one may not notice it immediately; if not vented promptly, it accumulates over time before manifesting. Symptoms include numbness all over the body, followed by the appearance of white scales and red macules, spreading like petechiae, resembling snake skin, and shedding in patches. At onset, progression from top to bottom is considered favorable (Shun), while from bottom to top is unfavorable (Ni); gradual onset is treatable, whereas sudden onset is difficult to cure. When wind-toxin enters the interior and transforms into worms, these worms erode the five zang organs, leading to five types of physical damage: Lung involvement causes eyebrow loss first; Liver involvement causes purple blisters on the face; Kidney involvement causes perforation in the soles of the feet first; Spleen involvement causes the whole body to resemble tinea; Heart involvement damages the eyes first. These are critical conditions. There are also five types of death signs: numbness and insensibility indicate "Skin Death"; inability to feel pain upon cutting indicates "Flesh Death"; ulceration without pus indicates "Blood Death"; detachment of hands and feet indicates "Sinew Death"; collapse of the nasal bridge, rupture of eyelids, eversion of lips, and hoarseness indicate "Bone Death". If any one of the five death signs appears, it signifies a deteriorating, incurable prognosis. Upon initial sensation of the disease, administer Wan Ling Dan (Ten Thousand Spirit Pill) to induce sweating. Subsequently, administer Shen Ying Xiao Feng San (Divine Response Wind-Expelling Powder), Zhui Feng San (Wind-Chasing Powder), and Mo Feng Wan (Wind-Grinding Pills) in sequence. For bleeding gums, rinse with a decoction of equal parts Huang Lian (Coptidis Rhizoma) and Guan Zhong (Cyatheae Spicosa). Externally apply Lei Ju Qu Feng San (Gathered Wind-Expelling Powder), combined with a bath/fumigation using Di Gu Pi (Lycii Cortex), Jing Jie (Schizonepetae Herba), Ku Shen (Sophorae Flavescentis Radix), and Xi Xin (Asari Radix), each two liang, decocted in river water. For cases involving tissue destruction, if located in the upper body, use Zui Xian San (Intoxicating Immortal Powder); if in the lower body, use Tong Tian Zai Zao San (Heaven-Penetrating Rebirth Powder). If the nasal bridge has collapsed, use Huan Ji San (Muscle-Replacing Powder) internally. If the patient shows slight deficiency signs, administer Bu Qi Xie Rong Tang (Tonify Qi and Drain Ying Decoction) and drink He Shou Wu Jiu (Polygoni Multiflori Wine). If one can cultivate mental clarity and reduce desires, observe dietary restrictions, and seek early treatment, there may be hope for recovery. However, if one cannot maintain a bland diet or abstain from sexual activity, recurrence is inevitable even after apparent recovery, ultimately leading to death.

Formula: Shen Ying Xiao Feng San (Divine Response Wind-Expelling Powder)
Composition: Quan Xie (Scorpio), Bai Zhi (Angelicae Dahuricae Radix), Ren Shen (Ginseng Radix et Rhizoma) (each 1 liang).
Pulverize into fine powder. Take 2 qian per dose. Avoid dinner. The next morning, take on an empty stomach mixed with warm wine. Mild bodily restlessness indicates efficacy.

[Verse] Shen Ying Xiao Feng San treats Leprosy, with body numbness, white scales, and red macules appearing. Quan Xie, Bai Zhi, and Ren Shen are each one liang; taken with wine on an empty stomach, numbness subsides.

Another Formula: Zhui Feng San (Wind-Chasing Powder)
Composition: Jin Wen Da Huang (Rhei Radix et Rhizoma, six liang), Chuan Yu Jin (Curcumae Longae Radix, stir-fried, 1.8 liang), Zao Jiao Ci (Gleditsiae Sinensis Spina) (1.5 liang).
Grind into fine powder. Take 5 qian per dose, add 1.5 qian of Feng Zi You (Aleuritidis Fructus Oil), and 1 qian of Po Xiao (Natrii Sulfas). Mix with warm wine and take at dawn (Wu Geng) on an empty stomach. Wait until Chen hour (7-9 AM), then take another dose as before, adding a little cooked honey to relieve the taste. Do not lie down. Several episodes of painful diarrhea are acceptable; replenish with thin congee. If Shen Ying Xiao Feng San is taken on the first day, take this formula on the second day, and Mo Feng Wan on the third day, repeating the cycle. For emaciated patients, take Zhui Feng San only once within ten days; do not administer to elderly or weak patients.

[Verse] Zhui Feng San uses Chuan Yu Jin, Zao Ci and Da Huang ground evenly. First take Xiao Feng San, then this one; mixed with wind oil and wine, it works miraculously.

Another Formula: Mo Feng Wan (Wind-Grinding Pills)
Composition: Xi Xian Cao (Siegesbeckiae Herba), Niu Bang Zi (Arctii Fructus, stir-fried), Ma Huang (Ephedrae Herba), Cang Er Cao (Xanthii Herba), Xi Xin (Asari Radix), Chuan Xiong (Ligustici Chuanxiong Rhizoma), Dang Gui (Angelicae Sinensis Radix), Jing Jie (Schizonepetae Herba), Man Jing Zi (Viticis Semen), Fang Feng (Saposhnikoviae Radix), Che Qian Zi (Plantaginis Semen), Wei Ling Xian (Clematidis Radix et Rhizoma), Tian Ma (Gastrodiae Rhizoma), He Shou Wu (Polygoni Multiflori Radix), Qiang Huo (Notopterygii Rhizoma et Radix), Du Huo (Angelicae Pubescentis Radix) (each 1 liang).
Grind into powder, make pills with wine and wheat paste, size of Sophora seeds. Take 60-70 pills per dose, washed down with warm wine, twice daily.

[Verse] Mo Feng Wan contains Xi Xian, Niu Bang, Ma Huang, Cang Er, Xi Xin, Chuan Xiong, Dang Gui, Jing Jie, Man Jing, Fang Feng, Che Qian, Wei Ling, Tian Ma, He Shou Wu, Qiang Huo, and Du Huo. Use this formula after taking Zhui Feng San.

Another Formula: Lei Ju Qu Feng San (Gathered Wind-Expelling Powder)
Composition: Liu Huang (Sulfur), Han Shui Shi (Halloysitum Rubrum), Ku Bai Fan (Alumen Exsiccatum), Guan Zhong (Cyatheae Spicosa) (each 2 liang), She Chuang Zi (Cnidii Fructus) (1 liang), Po Xiao (Natrii Sulfas) (5 qian).
Grind into fine powder. In the twelfth lunar month, mix with lard until smooth and apply externally.

[Verse] Lei Ju Qu Feng San contains Liu Huang, Han Shui Shi, Ku Bai Fan, Po Xiao, and She Chuang Zi. Guan Zhong is finely ground and mixed with lard; specifically applied to leprous sores all over the body.

Another Formula: Zui Xian San (Intoxicating Immortal Powder)
Composition: Niu Bang Zi (Arctii Fructus, stir-fried), Hu Ma (Sesami Fructus), Gou Qi Zi (Lycii Fructus), Man Jing Zi (Viticis Semen) (each 1 liang), Ku Shen (Sophorae Flavescentis Radix), Bai Ji Li (Tribuli Fructus), Fang Feng (Saposhnikoviae Radix), Hua Fen (Trichosanthis Radix) (5 qian).
Grind into fine powder. Take 1 qian per dose, add 1.2 li of Qing Fen (Calomel), mix well, and take with tea infusion. Take once in the morning, noon, and evening. After 5-7 days, foul yellow saliva will emerge from the teeth gaps, accompanied by whole-body pain and oppression as if crushed. Then, pus, blood, foul matter, and odor will be discharged via defecation, eliminating the root of the disease.

[Verse] Zui Xian San is heavy for upper-body Leprosy. It contains Niu Bang, Hu Ma, Gou Qi, Man Jing Zi, Ku Shen, Bai Ji Li, Fang Feng, and Hua Fen. Add Qing Fen when taking, mixed with tea infusion.

Another Formula: Tong Tian Zai Zao San (Heaven-Penetrating Rebirth Powder)
Composition: Da Huang (Rhei Radix et Rhizoma, roasted, 1 liang), Zao Jiao Ci (Gleditsiae Sinensis Spina) (1.5 liang), Yu Jin (Curcumae Longae Radix) (5 qian), Bai Qian Niu (Pharbitidis Semen, head powder, half raw, half stir-fried, 6 qian).
Grind into fine powder. Take 2-3 qian per dose. In the morning, face east, and take with strong wine. Efficacy is indicated by the discharge of foul matter (pus or worms) on the same day.

[Verse] Tong Tian Zai Zao San treats Leprosy, attacking destructive lesions starting from the lower body. Yu Jin, Da Huang, Qian Niu, and Zao Ci are taken in the morning with wine, facing east.

Another Formula: Huan Ji San (Muscle-Replacing Powder)
Composition: Wu Shao She (Zaocys), Bai Hua She (Bungarus multicinctus), Qiu Yin (Earthworm, cleaned, each 1 liang), Xi Xin (Asari Radix), Mu Bie Zi (Momordicae Semen), Bai Zhi (Angelicae Dahuricae Radix), Tian Ma (Gastrodiae Rhizoma, with stem), Chi Shao (Paeoniae Radix Rubra), Man Jing Zi (Viticis Semen), Dang Gui (Angelicae Sinensis Radix), Wei Ling Xian (Clematidis Radix et Rhizoma), Jing Jie Sui (Schizonepetae Spica), Gan Ju Hua (Chrysanthemi Flos), Bu Hui Mu (Asbestus), Zi Shen (Bistortae Rhizoma), Ku Shen (Sophorae Flavescentis Radix), Sha Shen (Glehniae Radix seu Adenophorae Radix), He Shou Wu (Polygoni Multiflori Radix), Shi Chang Pu (Acori Tatarinowii Rhizoma), Mu Zei (Equiseti Herba), Tian Dong (Asparagi Radix, heart removed), Chuan Xiong (Ligustici Chuanxiong Rhizoma), Bai Ji Li (Tribuli Fructus), Gan Cao (Glycyrrhizae Radix et Rhizoma, roasted), Hu Ma Ren (Sesami Semen), Cang Zhu (Atractylodis Rhizoma, soaked in rice wash water, stir-fried), Cao Wu (Aconiti Radix Preparata, boiled and peeled, each 3.5 qian).
Grind into fine powder. Take 5 qian per dose, mixed with warm wine; more wine is better. Zi Shen and Bu Hui Mu are optional.

[Verse] Huan Ji San treats severe leprous sores where toxin attacks causing eyebrow loss and nasal collapse. It contains Wu Shao She, Bai Hua She, Earthworm, Xi Xin, Mu Bie Zi, Bai Zhi, Tian Ma, Chi Shao, Man Jing Zi, Dang Gui, Wei Ling Xian, Jing Jie Sui, Gan Ju Hua, Bu Hui Mu, Zi Shen, Ku Shen, Sha Shen, He Shou Wu, Shi Chang Pu, Mu Zei, Tian Dong, Chuan Xiong, Bai Ji Li, Gan Cao, Hu Ma Ren, Cang Zhu, and Cao Wu.

Another Formula: Bu Qi Xie Rong Tang (Tonify Qi and Drain Ying Decoction)
Composition: Lian Qiao (Forsythiae Fructus, heart removed), Sheng Ma (Cimicifugae Rhizoma) (each 6 fen), Jie Geng (Platycodonis Radix) (5 fen), Huang Qin (Scutellariae Radix), Sheng Di Huang (Rehmanniae Radix) (each 4 fen), Huang Lian (Coptidis Rhizoma), Qiu Yin (Earthworm, wine-fried, cleaned), Dang Gui (Angelicae Sinensis Radix), Huang Qi (Astragali Radix), Su Mu (Sappan Lignum), Quan Xie (Scorpio) (each 3 fen), Ren Shen (Ginseng Radix et Rhizoma), Bai Dou Kou (Amomi Fructus Rotundus) (each 2 fen), Gan Cao (Glycyrrhizae Radix et Rhizoma, raw, 1 fen).
Add 2 zhong of water and 1 zhong of wine. Decoct to 1 zhong, strain. Separately, grind Hu Tong Lei (Populi Tears), 3 Shui Zhi (Hirudo, stir-fried), 3 Meng Chong (Tabanidae, stir-fried), 5 li of She Xiang (Moschus), and 3 Tao Ren (Persicae Semen, pounded into paste) into powder. Add this powder to the decoction, simmer to 0.7 zhong, and take after meals.

[Verse] Bu Qi Xie Rong Tang is suitable for deficiency in Leprosy. It contains Huang Qin, Huang Lian, Ren Shen, Jie Geng, Qiu Yin, Dang Gui, Huang Qi, Su Mu, Sheng Di, Sheng Ma, Quan Xie, Lian Qiao, Bai Dou Kou, Gan Cao, Hu Tong Lei, Shui Zhi, Meng Chong, She Xiang, and Tao Ren paste.

Another Formula: He Shou Wu Jiu (Polygoni Multiflori Wine)
Composition: He Shou Wu (Polygoni Multiflori Radix) (4 liang), Dang Gui Shen (Ginseng Radix et Rhizoma part? No, Angelicae Sinensis Radix - root stock), Dang Gui Wei (Angelicae Sinensis Radix - tail), Chuan Shan Jia (Manis Squama, roasted), Sheng Di Huang (Rehmanniae Radix), Shu Di Huang (Rehmanniae Radix Preparata), Xia Ma (Bufo bufo gargarizans or similar toad, each 1 liang), Ce Bai Ye (Platycladi Cacumen), Song Zhen (Pinus needle), Wu Jia Pi (Acanthopanacis Cortex), Chuan Wu (Aconiti Radix Preparata, boiled and peeled), Cao Wu (Aconiti Radix Preparata, boiled and peeled, each 4 qian).
Place herbs in a summer cloth bag, tie tightly. Add 20 jin of yellow wine to a jar, place the herb bag inside, seal tightly. Boil in a double boiler for the time it takes three incense sticks to burn. Bury and store for seven days. Open the jar, take the wine, drink regularly until slightly intoxicated, induce sweating, and avoid wind.

[Verse] He Shou Wu Jiu treats severe Leprosy. It contains Dang Gui Shen/Wei, Chuan Shan Jia, Song Zhen, Sheng/Shu Di Huang, Ce Bai Ye, Xia Ma, Wu Jia Pi, Chuan Wu, and Cao Wu. Wine-boiled to nourish Ying and extinguish toxin.

Another Formula: Wan Ling Dan (Ten Thousand Spirit Pill) (See Swollen Ulcer Section)