【方歌】结毒杨梅毒结生，原于误服劫药成，日久逢虚始倒发，
脑鼻喉目任蚀攻。
【注】此证因生杨梅方炽，误服水银升炼悍燥劫药，希图速效
，疮痂尽落，一时侥幸而愈，不知遗害久远，引毒潜藏
骨髓关窍之中，其毒积久，因经虚外攻，故名结毒倒发
。其始先从筋骨疼痛，随处结肿，皮色如常；将烂时，
色方紫红，腐臭不堪，以致脑顶塌陷，腮唇鼻梁损坏，
穿喉蚀目，手足拘挛等患，终成痼疾。初起结肿，筋骨
疼痛时，宜服搜风解毒汤。若遍身破烂臭秽，而兼筋骨
疼痛，气实毒盛者，宜服化毒散；气衰者，猪胰子汤主
之。若结毒肿块，经年难愈，诸法罔效者，宜西圣复煎
丸主之；若结毒攻于口鼻者，宜五宝散主之。年久臭烂
，鼻破损坏者，宜服结毒紫金丹。若入巅顶，头痛如破
者，内服天麻饼子，鼻吸碧云散；若鼻塞不通，宜吹通
鼻散，甚效。毒攻咽喉，腐烂臭蚀者，宜服硫黄不二散
，兼吹结毒灵药，兑人中白。若结毒筋骨疼痛，朝轻夜
重，喜热手按揉者，系犯寒凉，宜铅回散主之。结毒臭
烂不敛，宜贴解毒紫金膏，兼撒结毒灵药。壮实者，以
解毒为主；虚弱者，以兼补为法。以上之证，各随次第
，如法调治，重者一年，轻者半年，自然可痊，永无后
患，慎勿妄求速效，以自贻误也。
方剂：搜风解毒散
组成：土茯苓（一两） 白藓皮
金银花 薏苡仁
防风 木通
木瓜（各五分） 皂角子（四分）
水二钟，煎一钟服之，一日三服。
气虚加人参七分，血虚加当归七分。
忌清茶、牛、羊、鸡、鹅、鱼、肉、烧酒、房欲等
件。
【方歌】搜风解毒汤倒发，初肿拘急骨痛加，土苓白藓银花薏，
皂角防风通木瓜。
又方：化毒散
组成：生大黄（一两） 穿山甲（炙）
当归尾（各五钱） 白僵蚕（炒，三钱）
蜈蚣（炙黄，一条）
共研细末，每服二钱，温酒调下，一日二服。
【方歌】化毒散医结毒盛，破秽气实筋骨疼，大黄山甲僵归尾，
蜈蚣研末酒调成。
又方：猪胰子汤
组成：猪胰子（切碎，一两） 黄耆（盐水炒）
金银花（各三钱） 当归
白芍（酒炒，各一钱五分） 天花粉
贝母（去心研） 穿山甲（炙，研）
白藓皮 青风藤
白芷 木瓜
皂刺 甘草节（各一钱）
黄栝蒌（连仁研烂，一个） 防己（七分）
鳖虱胡麻（炒，研，二钱）
白色土茯苓四两，河水四大碗，煎汤三碗，去滓将
群药入汤内，煎一大碗，通口服；胃弱者分为二服。日
三服。
【方歌】猪胰汤治结毒虚，归芍天花蒌贝耆，胡麻银甲鲜藤芷，
木瓜己刺草苓宜。
又方：西圣复煎丸
组成：乳香 没药
孩儿茶 丁香（各一两）
血竭 阿魏
白花蛇（各四钱）
飞罗面（炒焦黄色，一斤）共研细，
炼蜜六两，煎滚香油四两，大枣肉二十枚，捣膏共
和为丸，如弹子大，每服一丸；土茯苓二两，水二钟，
煎至一钟，将药丸入内，再煎至半钟，澄去渣温服。
【方歌】西圣复煎丸结毒，肿块经年服自无，乳没儿茶丁血竭，
阿魏白蛇面炒和。
又方：结毒紫金丹
组成：龟板（放在炭火上炙焦，用白酒浆涂之再灸，以焦黄为
度，研末）
朱砂（六钱）
石决明（用九孔大者，〔火段〕红童便淬一次，六钱）
细各研细末，共和匀，烂米饭为丸，麻子大。每服
一钱，量病上、下，食前后服之。筋骨疼痛酒下；腐烂
者土茯苓汤下。
【方歌】结毒紫金丹龟板，石决朱砂米饭丸，年久毒攻鼻损破，
土苓汤服臭烂痊。
又方：天麻饼子
组成：天麻 薄荷
甘松 白附子（去皮）
白芷 苍术（米泔水浸，炒）
川芎 川乌（汤泡，去皮）
草乌（汤泡，去皮） 防风
细辛 甘草（生，各一钱）
雄黄 全蝎（各三钱）
上为细末，寒食面打糊为丸，如豌豆大，捻作饼子
。每服二、三十饼，葱白煎汤送下。
【方歌】天麻饼子薄甘松，雄黄白附芷苍芎，川草乌蝎防细草，
结毒攻巅头痛平。
又方：通鼻散
组成：壶卢壳（烧灰） 石钟乳
胆矾 冰片（各等分）
共为末，吹入鼻内，出黄水，日吹二、三次，三、
二日即通。
【方歌】通鼻散吹结毒证，毒塞鼻中息不通，石钟乳与壶卢壳，
胆矾冰片等分同。
又方：硫黄不二散
组成：硫黄（一钱） 靛花（一分）
共研细，用凉水一酒钟调服。
【方歌】硫黄不二毒攻喉，腐臭烂蚀痛不休，凉水调服疼立止，
靛花少兑不须忧。
又方：结毒灵药
组成：水银（一两） 朱砂
硫黄 雄黄（各三钱）
共研细，入阳城罐内，泥固铁盏粱，兜固紧封口，
其火候俱按红升丹之炼法，火毕，次日取出，盏底灵药
约有一两五、六钱，治寻常腐烂之证，灵药五钱、轻粉
五钱，同研细，小罐盛收，以纱封之；临用时，甘草汤
洗净患处，将罐倒悬，纱眼内筛药患上。油纸盖之，男
妇咽喉烂者，灵药一钱，加人中白二分，研细吹之，日
用三次。
【方歌】结毒灵药化腐方，水银研砂硫雄黄，共研入罐用泥固，
兜紧火升三炷香。
又方：铅回散
组成：黑铅（铜杓化开，倾入水中，取起再化再倾，以铅化尽
为度，澄去水，将铅灰倾在三重纸上，下用灰收
干水气，铅灰日中晒干）
硫黄
各等分，共研细，每服一钱，温酒调服。至重者，
不过三次即效。
【方歌】铅回散疗筋骨痛，寒触结毒夜间重，铅化成灰兑硫黄，
每服五钱酒调送。
又方：五宝散（见下部疳疮）
碧云散（见头部头风伤目）
结毒紫金膏（见胫部〔月廉〕疮）
[Formula Song] The condyloma acuminatum (genital wart) and syphilitic toxin arise from knots; originally caused by the mistaken ingestion of drastic purgatives. After a long time, when deficiency occurs, it erupts retrogradely, allowing the toxin to erode the brain, nose, throat, and eyes at will.
[Annotation] This condition arises because, during the intense phase of chancre (syphilis), one mistakenly ingests drastic purgatives refined from mercury, which are harsh and dry, hoping for a rapid cure. The scabs fall off completely, and there is a temporary, fortuitous recovery. However, this does not realize that it leaves lasting harm, drawing the toxin to hide secretly within the bone marrow and orifices. As the toxin accumulates over time, it attacks outward due to channel deficiency; hence it is named "condyloma acuminatum retrograde eruption." Initially, it begins with pain in the sinews and bones, swelling forming anywhere, with normal skin color; when about to ulcerate, the color becomes purple-red, with unbearable foul odor, leading to collapse of the crown of the head, damage to the cheeks, lips, and nasal bridge, perforation of the throat and erosion of the eyes, contracture of the hands and feet, and other ailments, ultimately becoming an intractable disease. When initially presenting with swelling and pain in the sinews and bones, one should take Sofeng Jiedu Decoction (Wind-Searching Toxin-Resolving Decoction). If the whole body is ulcerated and foul-smelling, accompanied by pain in the sinews and bones, and the Qi is excess with abundant toxin, one should take Huadu Powder (Toxin-Resolving Powder); if the Qi is deficient, Zhuyizi Decoction (Pig Pancreas Decoction) should be used as the main treatment. If the condyloma acuminatum lumps cannot heal after years and all methods fail, Xisheng Fujian Pills (Western Sage Re-Decoction Pills) should be used as the main treatment; if the condyloma acuminatum toxin attacks the mouth and nose, Wubao Powder (Five Treasures Powder) should be used as the main treatment. For long-standing foul rot and broken nose, one should take Jiedu Zijin Pill (Condyloma Acuminatum Purple Gold Pill). If it enters the vertex, causing headache as if breaking, internally take Tianma Bingzi (Gastrodia Biscuits) and insufflate Biyun San (Green Cloud Powder) into the nose; if nasal congestion prevents breathing, insufflate Tongbi San (Nose-Unblocking Powder), which is very effective. If the toxin attacks the throat, causing rotting and foul erosion, take Liuhuang Bu'er San (Sulfur Unmatched Powder) and simultaneously insufflate Jiedu Lingyao (Condyloma Acuminatum Spiritual Medicine) mixed with Narenzhongbai (Human Urine Deposit). If the condyloma acuminatum causes pain in the sinews and bones, lighter in the morning and heavier at night, preferring warm hand massage, it is due to cold-cold injury; Qianhui San (Lead Return Powder) should be used as the main treatment. For condyloma acuminatum foul rot that does not heal, apply Jiedu Zijin Ointment (Toxin-Resolving Purple Gold Ointment) and sprinkle Jiedu Lingyao. For robust individuals, focus on resolving toxin; for weak individuals, use a method combining tonification. For the above conditions, treat according to the sequence and method; severe cases take one year, mild cases half a year, naturally recovering without future complications. Do not recklessly seek rapid cures to cause self-harm.
Formula: Sofeng Jiedu San (Wind-Searching Toxin-Resolving Powder)
Composition: Tufuling (Smilax Glabra Rhizome, 1 liang), Baixianpi (Dermatophyllum Root Bark), Jinyinhua (Lonicerae Japonicae Flos), Yiyiren (Coicis Semen), Fangfeng (Saposhnikoviae Radix), Mutong (Akebiae Caulis), Mugua (Chaenomelis Fructus, each 5 fen), Zaojiaozì (Gleditsiae Sinensis Spina, 4 fen).
Boil 2 zhong of water until reduced to 1 zhong, take orally, three times a day.
For Qi deficiency, add Renshen (Ginseng Radix et Rhizoma, 7 fen); for Blood deficiency, add Danggui (Angelicae Sinensis Radix, 7 fen).
Avoid clear tea, beef, mutton, chicken, goose, fish, meat, distilled liquor, and sexual activity.
[Formula Song] Sofeng Jiedu Tang treats retrograde eruption, adding for initial swelling, stiffness, and bone pain: Tufuling, Baixianpi, Jinyinhua, Yiyiren, Zaojiao, Fangfeng, Mutong, Mugua.
Another Formula: Huadu San (Toxin-Resolving Powder)
Composition: Sheng Dahuang (Rhei Radix et Rhizoma, 1 liang), Chuanshanjia (Pangolin Scales, roasted), Dangguiwei (Angelicae Sinensis Radix Tail, each 5 qian), Baijiangcan (Bombyx Batryticatus, stir-fried, 3 qian), Wugong (Centipedae Corpus, roasted yellow, 1 piece).
Grind into fine powder, take 2 qian per dose, mixed with warm wine, twice a day.
[Formula Song] Huadu San treats excessive condyloma acuminatum toxin, breaking filth, excess Qi, and sinew-bone pain: Dahuang, Chuanshanjia, Jiangcan, Dangguiwei; grind Wugong into powder and mix with wine.
Another Formula: Zhuyizi Tang (Pig Pancreas Decoction)
Composition: Zhuyizi (Pig Pancreas, chopped, 1 liang), Huangqi (Astragali Radix, stir-fried with salt water), Jinyinhua (Lonicerae Japonicae Flos, each 3 qian), Danggui (Angelicae Sinensis Radix), Baishao (Paeoniae Radix Alba, stir-fried with wine, each 1.5 qian), Tianhuafen (Trichosanthis Radix), Beimu (Fritillariae Bulbus, dehearted and ground), Chuanshanjia (Pangolin Scales, roasted and ground), Baixianpi (Dermatophyllum Root Bark), Qingfengteng (Sinomenii Caulis), Baizhi (Angelicae Dahuricae Radix), Mugua (Chaenomelis Fructus), Zaoci (Gleditsiae Sinensis Spina), Gancaojie (Glycyrrhizae Radix et Rhizoma Nodes, each 1 qian), Huanggualou (Trichosanthis Fructus, including seeds, ground soft, 1 fruit), Fangji (Stephaniae Tetrandrae Radix, 7 fen), Bieshi Huma (Cannabis Semen, stir-fried and ground, 2 qian).
White Tufuling (Smilax Glabra Rhizome, 4 liang), four large bowls of river water, decoct to three bowls, remove dregs, add the group of herbs into the decoction, decoct to one large bowl, take orally all at once; for those with weak stomachs, divide into two doses. Three times a day.
[Formula Song] Zhuyizi Tang treats deficient condyloma acuminatum: Danggui, Baishao, Tianhuafen, Gualou, Beimu, Huangqi; Huma, Jinyinhua, Chuanshanjia, Qingfengteng, Baizhi, Mugua, Fangji, Zaoci, Gancao, Tufuling are suitable.
Another Formula: Xisheng Fujian Wan (Western Sage Re-Decoction Pills)
Composition: Ruxiang (Olibanum), Moyao (Myrrha), Haiercha (Child's Tea), Dingxiang (Caryophylli Flos, each 1 liang), Xuexie (Dracaenae Sangue), Awei (Ferulae Resina), Baihuashe (Bungarus Parvus, each 4 qian), Feiluomian (Fine Wheat Flour, stir-fried to scorched yellow, 1 jin). Grind together finely, refine honey 6 liang, boil sesame oil 4 liang, twenty jujube meats, pound into paste, mix together to form pills like bullet size, take one pill per dose; Tufuling (Smilax Glabra Rhizome) 2 liang, water 2 zhong, decoct to 1 zhong, put the pill inside, decoct again to half zhong, filter dregs, take warm.
[Formula Song] Xisheng Fujian Wan treats condyloma acuminatum, lumps persisting for years disappear upon taking: Ruxiang, Moyao, Haiercha, Dingxiang, Xuexie, Awei, Baihuashe, stir-fried flour mixed.
Another Formula: Jiedu Zijin Dan (Condyloma Acuminatum Purple Gold Pill)
Composition: Guiban (Testudinis Carapax et Plastrum, roasted over charcoal until scorched, coated with white wine slurry and roasted again until scorched yellow, then ground into powder), Zhusha (Cinnabar, 6 qian), Shijueming (Haliotidis Concha, use large nine-hole ones, roast red and quench in child's urine once, 6 qian).
Grind each finely, mix evenly, form pills with rotten rice flour, size of hemp seeds. Take 1 qian per dose, measure upper or lower disease location, take before or after meals. For sinew-bone pain, take with wine; for rotting, take with Tufuling decoction.
[Formula Song] Jiedu Zijin Dan uses Guiban, Shijueming, Zhusha, rice flour pills; for long-standing toxin attacking nose causing breakage, take with Tufuling decoction to cure foul rot.
Another Formula: Tianma Bingzi (Gastrodia Biscuits)
Composition: Tianma (Gastrodiae Rhizoma), Bohe (Menthae Haplocalycis Herba), Gansong (Nardostachyos Radix et Rhizoma), Baifuzi (Typhonii Rhizoma, peeled), Baizhi (Angelicae Dahuricae Radix), Cangzhu (Atractylodis Rhizoma, soaked in rice wash water, stir-fried), Chuanxiong (Chuanxiong Rhizoma), Chuanwu (Aconiti Radix, soaked in water, peeled), Caowu (Aconiti Kusnezoffii Radix, soaked in water, peeled), Fangfeng (Saposhnikoviae Radix), Xixin (Asari Radix et Rhizoma), Gancao (Glycyrrhizae Radix et Rhizoma, raw, each 1 qian), Xionghuang (Realgar), Quanxie (Scorpio, each 3 qian).
Make into fine powder, use Han Shi Mian (Cold Food Noodle) to make paste, form pills like pea size, shape into biscuits. Take 20-30 biscuits per dose, send down with scallion white decoction.
[Formula Song] Tianma Bingzi uses Bohe, Gansong, Xionghuang, Baifuzi, Baizhi, Cangzhu, Chuanxiong, Chuanwu, Caowu, Quanxie, Fangfeng, Xixin, Gancao; treats condyloma acuminatum attacking vertex, calming headache.
Another Formula: Tongbi San (Nose-Unblocking Powder)
Composition: Huluke (Calabash Shell, burnt to ash), Shizhongru (Gypsum Fibrosum), Danfan (Alumen), Bingpian (Borneolum Syntheticum, equal parts).
Grind into powder, insufflate into nose, yellow fluid comes out, insufflate 2-3 times a day, unblocked in 2-3 days.
[Formula Song] Tongbi San insufflates for condyloma acuminatum condition, toxin blocking nose preventing breath: Shizhongru, Huluke shell, Danfan, Bingpian in equal parts.
Another Formula: Liuhuang Bu'er San (Sulfur Unmatched Powder)
Composition: Liuhuang (Sulfur, 1 qian), Dianhua (Indigo Naturalis, 1 fen).
Grind finely, mix with cool water (one wine cup) and take orally.
[Formula Song] Liuhuang Bu'er San treats toxin attacking throat, rotting, foul erosion, ceaseless pain: Mix with cool water, pain stops immediately; add little Dianhua, no need to worry.
Another Formula: Jiedu Lingyao (Condyloma Acuminatum Spiritual Medicine)
Composition: Shuiyin (Mercurius, 1 liang), Zhusha (Cinnabar), Liuhuang (Sulfur), Xionghuang (Realgar, each 3 qian).
Grind finely, put into Yangcheng jar, seal with mud and iron lid tightly, fire control follows the refining method of Hongshengdan (Red Ascending Pill). After firing, take out next day, spiritual medicine at bottom of lid is about 1.5-1.6 liang. Treats ordinary rotting conditions: 5 qian spiritual medicine, 5 qian Qingfen (Calomel), grind together finely, store in small jar, seal with gauze; when using, wash lesion with Gancao decoction, hang jar upside down, sieve medicine onto lesion through gauze holes. Cover with oil paper. For men and women with rotten throat, 1 qian spiritual medicine, add 2 fen Narenzhongbai (Human Urine Deposit), grind finely and insufflate, three times daily.
[Formula Song] Jiedu Lingyao resolves rotting formula: Shuiyin ground with Shaju, Liuhuang, Xionghuang; grind together, put in jar, seal with mud, tighten lid, fire ascends for three incense sticks.
Another Formula: Qianhui San (Lead Return Powder)
Composition: Heiqian (Black Lead, melt in copper spoon, pour into water, take out, melt and pour again until lead is exhausted, filter water, pour lead ash onto triple-layer paper, collect dry water vapor with ash underneath, dry lead ash in sun), Liuhuang (Sulfur).
Equal parts, grind finely, take 1 qian per dose, mix with warm wine. For severe cases, effective within three doses.
[Formula Song] Qianhui San treats sinew-bone pain, cold touching condyloma acuminatum heavy at night: Lead melted into ash mixed with Liuhuang, take 5 qian per dose mixed with wine.
Another Formula: Wubao San (Five Treasures Powder) (See Lower Body Chancre)
Biyun San (Green Cloud Powder) (See Head Wind Injuring Eyes)
Jiedu Zijin Gao (Condyloma Acuminatum Purple Gold Ointment) (See Shin Ulcer)