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Yi disease also has five types: Qi Yi (Qi-type dysphagia), You Yi (Worry-type dysphagia), Shi Yi (Food-type dysphagia), Lao Yi (Fatigue-type dysphagia), and Si Yi (Pensive-type dysphagia). "Yi" refers to obstruction in the throat, discomfort in the chest and heart, and the inability to swallow food. Treatment should be based on the specific symptoms of each type.

Guang Wuxing Ji records: During the Yonghui era, a monk in Jiangzhou suffered from Yi disease for several years. On his deathbed, he left instructions to have his throat cut open for examination. A creature was found resembling a fish but with two heads, its entire body covered in fleshy scales. When placed in a bowl, it jumped incessantly. Various foods thrown into the bowl dissolved into water within moments. At that time, the temple was harvesting knotweed to make indigo dye. A small amount of this dye was tested in the bowl; the creature shrank back in fear around the rim of the bowl and also dissolved into water within moments. People subsequently used indigo dye to treat Yi disease (from Liang Fang).

Using fine bran from the head of a pestle to treat sudden dysphagia. Tao Hongjing stated: In cases of sudden food impaction where swallowing is impossible, scraping a small amount and holding it in the mouth will expel the obstruction. This aligns with the principle of pounding/grinding. The principles of things in the world often influence each other in such ways. Ri Huazi stated: To treat dysphagia generally, decoct and sip the liquid (from Bencao).

Hua Tuo was walking on the road when he saw a person suffering from Yi disease who wanted to eat but could not swallow. His family loaded him onto a cart to seek medical treatment. Hearing the patient's groans, Hua Tuo stopped his carriage, approached, and said to him, "There is a pancake vendor by the road ahead. Take three sheng of garlic paste and vinegar, drink it, and your illness will heal." Following Hua Tuo's advice, the patient immediately vomited up a snake, which he hung by his carriage. The patient wished to visit Hua Tuo, but Hua Tuo had not yet returned home. Hua Tuo's child was playing at the gate and saw the patient approaching. The child said to others, "The object hanging by the carriage must mean we have met our Master." Upon entering and seeing Hua Tuo, the patient noticed dozens of similar snakes hanging on the north wall of Hua Tuo's house (from Taiping Yulan).

When Wu Tingshao served as the Director of the Imperial Medical Bureau, Emperor Liezu suffered from throat obstruction after eating maltose syrup. None of the imperial physicians could cure him. Wu Tingshao, then unknown, alone asserted that Chushu Tang (Breadfruit Decoction) should be administered. After one dose, the disease disappeared. The other doctors memorized this silently. Later, they tried other methods without success. When asked why, he replied, "Dysphagia arises from sweet substances; therefore, I treated it with Chushu Tang" (from Nan Tang Shu).

All diseases arise from Qi. Anger causes Qi to rise upward; joy causes Qi to slacken; grief causes Qi to dissipate; fear causes Qi to sink downward; cold causes Qi to contract; heat causes Qi to escape outward; shock causes Qi to become chaotic; labor causes Qi to be depleted; and contemplation causes Qi to knot. The nine types of Qi differ, leading to different pathological manifestations.

The numbers of Heaven and Earth begin above and end below. For the first half of the year, Heavenly Qi dominates; for the second half, Earthly Qi dominates. They interact, and the intersection of Qi serves as the master. Thus, the annual cycle completes.

Excess of pathogenic Qi constitutes an Excess syndrome; depletion of essential Qi constitutes a Deficiency syndrome. Qi deficiency manifests as Lung deficiency; Qi rebellion manifests as cold feet. If the disease occurs out of season, there is hope for survival; if it occurs during the corresponding season, death ensues. The same logic applies to the other Zang-Fu organs.