一、痘当靥之时，色转苍羸，成紫葡萄色者，一二日，决从口鼻四边靥起，腹中收至两腿，然额上和
脚一齐收靥，落皮而愈，此乃吉证也，不必惊疑下药。
一、痘当靥之时，遍身臭烂，如拼搭不可近，目中无神者，决死。
一、痘当靥之时，遍身发痒，抓搭无脓者，皮卷如豆壳干者，决死。
一、痘当靥之时，寒战，手足颤掉，切牙噤口，即死。
一、痘当靥之时，目闭无神，腹胀，足冷过膝者，决死。
一、痘当靥之时，声哑气急，痰响，小便少，大便频者，决死。
一、痘当靥之时，痘瘢雪白，全无血色，过后亦死，急用消毒
散二帖，后用助气血药以养脾胃，或可得也，宜预先治之。
方
败草散 治痘疮抓搔成脓，血淋漓。
用盖房多年烂草，或盖墙烂草亦可，其草经霜露，感天地阴阳之气，善解疮毒，其功不能尽述，取
草不拘多少，晒干，或焙干，为末，干贴疮上，若浑身疮破，脓水不绝，粘贴衣裳，难以坐卧，
可用二三升摊于席上，令儿坐卧，其效如神，仍服木香散，加丁香、官桂同煎服。
硝胆膏
硝胆膏医口不收，疮瘢臭烂血脓流，宜研猪胆芒硝细末，患处涂之病自瘳。
猪胆汁、芒硝二味研匀，如膏，涂之。
脱甲散 治疮甲不落，不能靥者。
雄黄 蝉蜕皮（去土） 人顶骨（烧灰，各一钱）
上为细末，每服三分，米汤下。
雄黄散 治小儿牙断，生疳蚀疮。
雄黄（一钱） 铜绿（二钱）
二味共研极细末，量儿大小，干掺上。
绵茧散 治痘疮，身体肢节上有疳蚀疮，脓水不绝。
空蚕茧（须是出蚕蛾了者）
一味不拘多少，用生白矾研细入内，茧内令满，以炭火烧，令白矾汁干尽，取出研极细，每用干贴疮口上。
猪尾膏
龙脑（半字许，研细，旋滴猪心血为丸，辰砂为衣，紫草汤化下）
1. When the smallpox pustules are scabbing and falling off, if the color turns pale and emaciated, presenting a purple grape-like hue, within one or two days, the scabs will begin to form around the mouth and nose, receding from the abdomen down to both legs. However, if the forehead and feet scab simultaneously, healing after the skin peels off, this is an auspicious sign; there is no need for alarm or suspicion, nor should purgative medicines be administered.
2. When the smallpox pustules are scabbing and falling off, if the entire body is putrid and rotting, appearing as if stitched together and unapproachable due to foul odor, and the eyes lack spirit, death is certain.
3. When the smallpox pustules are scabbing and falling off, if the entire body itches, scratching yields no pus, and the skin curls up like dry bean pods, death is certain.
4. When the smallpox pustules are scabbing and falling off, if chills occur, limbs tremble, teeth are clenched, and the mouth is locked shut, death ensues immediately.
5. When the smallpox pustules are scabbing and falling off, if the eyes are closed without spirit, the abdomen is distended, and the feet are cold extending beyond the knees, death is certain.
6. When the smallpox pustules are scabbing and falling off, if the voice is hoarse with rapid breathing, phlegm rattles in the throat, urine output is scant, and bowel movements are frequent, death is certain.
7. When the smallpox pustules are scabbing and falling off, if the scar marks are snow-white with no blood color, death will follow later. Urgently administer two doses of Xiaodu San (Detoxification Powder), followed by herbs that tonify Qi and Blood to nourish the Spleen and Stomach; recovery may be possible. Treatment should be initiated in advance.
Formulas:
Baicao San (Rotten Grass Powder)
Indications: Smallpox sores becoming suppurative due to scratching, with dripping blood.
Usage: Use rotten grass from roofs used for many years, or rotten grass from walls. These grasses, having been exposed to frost and dew, absorb the Yin and Yang Qi of Heaven and Earth, and possess excellent properties for resolving sore toxins, though their full efficacy cannot be fully described. Take an unspecified amount of grass, dry it in the sun or bake it until dry, and grind it into powder. Apply the dry powder directly onto the sores. If the entire body is broken out with incessant pus, sticking to clothes and making sitting or lying difficult, spread two or three sheng [a traditional unit of volume] on the mat, allowing the child to sit or lie upon it. The effect is miraculous. Continue to administer Muxiang San (Costus Root Powder), decocted with Dingxiang (Clove) and Guigui (Cinnamon Twig).
Xiaodan Gao (Niter and Gallbladder Ointment)
Indications: Inability of the mouth/lips to close, foul-smelling scars with flowing bloody pus.
Usage: Grind Zhu Dan (Pig Gallbladder) and Mangxiao (Mirabilite) into fine powder. Apply to the affected area; the disease will heal spontaneously.
Preparation: Grind Pig Gallbladder and Mirabilite evenly to form an ointment, then apply.
Tuojia San (Falling Nail Powder)
Indications: Sores where the crusts/nails do not fall off, preventing proper scabbing.
Ingredients: Xionghuang (Realgar), Chantuitui (Cicada Slough, cleaned of soil), Rendingonggu (Human Vertex Bone, burnt to ash), each 1 qian.
Usage: Grind all ingredients into a fine powder. Take 3 fen per dose, washed down with rice water.
Xionghuang San (Realgar Powder)
Indications: Children with broken teeth, developing gan ulcers (nutritional deficiency sores) and erosive sores.
Ingredients: Xionghuang (Realgar) 1 qian, Tonglv (Malachite) 2 qian.
Usage: Grind both ingredients into an extremely fine powder. Apply dry powder appropriately according to the child's size.
Mianjian San (Silkworm Cocoon Powder)
Indications: Smallpox with gan erosive sores on the body and joints, with incessant pus.
Ingredients: Kong Canjian (Empty Silkworm Cocoon, specifically those from which moths have emerged).
Usage: Take an unspecified amount of empty cocoons. Fill them finely ground Sheng Baifan (Raw Alum). Burn over charcoal until the alum juice is completely dried. Remove, grind into an extremely fine powder, and apply dry powder to the sore openings.
Zhuwei Gao (Pig Tail Ointment)
Ingredients: Nao (Borneol, approx. half zi/grain, finely ground), mixed with fresh Pig Heart Blood to form pills, coated with Zhensha (Cinnabar).
Usage: Dissolve and administer with Zicao Tang (Arnebia Decoction).