论曰小儿病面黄发直，时时壮热，饮食不生肌肤，头项生核，状如瘤赘，以无辜而得，
故名无辜疳。由小儿嗜肥甘过多，虫因甘动，内缓脾气，饮食不调所致也。治之当如治诸疳
之法
粉，
漏不
治小儿一切无辜黄瘦腹痛疳痢，或有虫冷热，悉治之。丹砂丸方
丹砂 雄黄（各一分研） 干虾蟆（一枚去头足涂酥炙焦为末研） 石菖蒲 漏芦（各
一两）
上六味，以菖蒲漏芦，捣罗为末，与余四味，入乳钵同研匀再罗，粟米饭为丸，如麻子
大，每服二丸，米饮化下，空心午后各一服，随儿大小加减。
治小儿无辜疳，肌瘦有虫。漏芦丸方
漏芦（去芦头二两） 猪肝（爆干去膜） 楮根（锉各半两）
上三味，捣罗为末，炼蜜为丸，如麻子大，一二岁儿每服三丸，三四岁儿每服五丸。温
水下，乳食前，日二服，如患泻，米饮下。
治小儿无辜疳，头干腹大，益脑。地榆散方
地榆（微炙一两半） 蜗牛壳（去土） 青黛（研各一两） 麝香 人粪（烧灰） 兰
香根（烧
上八味，捣研为散，五十日儿一字匕，百日儿一字强，二百日儿半钱匕，米饮调下，不
拘时候。随儿大小加减。
治小儿无辜疳。鳖甲丸方
鳖甲（醋炙黄去裙 ） 黄连（去须） 桔梗（炒） 夜明砂（各一两） 诃黎勒皮（两
枚一
上七味，捣罗为末，以糯米饭为丸，如绿豆大，粥饮下七丸，疳痢亦宜服，日三。量儿
大小加减。
治小儿一切无辜疳，瘦不下食、腹胀。犀角散方
犀角屑 琥珀（研） 芦荟（研） 酸石榴东南根皮（炙锉） 木香 诃黎勒皮 龙脑
（各三
上一十一味，捣罗为散，一二岁儿半钱匕，三四岁一钱匕，米饮调下，不以时候，量儿
大小加减。
治小儿无辜疳气，寒热积滞不化，心腹胀痛。芦荟散方
芦荟（研） 人中白（研） 虾蟆（炙黄各半两） 麝香（研一分）
上四味，捣研为散，再合研令细，每服一字，至半钱匕，熟水调下，不拘时候，日二服
，后当下恶物，量儿大小加减。
治小儿无辜疳，项细腹大，发干作穗。鳖甲汤方
鳖甲（去裙 炙令焦） 陈橘皮（汤浸去白焙） 苍术（去皮米泔浸一宿切焙） 赤茯
苓（
上六味，粗捣筛，一二岁儿一钱匕，水七分，煎至四分，去滓分温二服、日再。量儿大
小加减。
治小儿无辜疳。鳖甲散方
鳖甲（去裙 醋炙焦） 诃黎勒（去核） 苍术（去皮米泔浸切焙） 木香 赤茯苓（去
黑
上六味，捣罗为散，一二岁儿半钱匕，熟水调下。食前、日二服，量儿大小加减。
治小儿无辜疳痢。丹砂散方
丹砂（研） 丁香（各半两） 白马夜眼（一分微炒）
上三味，捣研为散，空心以井华水调半钱匕，后服雉肝散。
治小儿无辜疳。雉肝散方
雉肝（一具干者捣湿者熬为末）
上一味，分三服，每服丹砂散后，即一服，米饮调下半钱匕。
治小儿无辜疳。蜗牛煎方
蜗牛壳（七枚旧死者皮薄黄白色者是）
上一味净洗，不得小有尘土。漉干纳酥蜜壳中，瓷盏盛，纸糊头，炊饭上蒸之。下
时即坐甑中，装饭又蒸饭熟，细研如水淀，渐渐与服，一日服尽
治小儿十岁以下，至新生百日，无问痫热无辜等。皆疗之。雄黄丸方
雄黄 丹砂 牛黄 麝香 石膏（并研细） 蕤仁（去皮） 甘遂（微炒） 牡蛎（炒
研各半
上九味，捣研为末，炼蜜和捣，丸如粟米大，一二岁儿服二丸，米饮下，三四岁三丸，
微利为度，随儿大小加减。
治小儿无辜疳泻。四神散方
虾蟆（一枚炙） 黄连（去须为末） 铅丹（炒各半两） 麝香（半分）
上四味，细研为散，每服半钱匕，陈米饮调下。
治小儿无辜疳，腹胀气喘，四肢虚浮，乍热乍寒，或即泻痢，心腹坚痛。救生丸方
巴豆（去皮取仁半两米醋一升生姜半两切同煮醋尽取巴豆烂研） 雄黄（半两研） 丹
砂（
上三味，合研匀，以汤浸蒸饼心为丸，如黄米大，每日以芍药汤下二丸。
治小儿无辜疳。刘老丸方
陈粳米（一合炒过去火毒用） 黄连（去须一两锉炒放冷出火毒） 陈橘皮（去白半两）
干
上四味，捣为末，猪胆汁煮面糊为丸，如小豆大，每服七丸，米饮下，不拘时。
治小儿无辜疳，面黄发直，时时壮热，饮食不成肌肉。棘刚子丸方
棘刚子（为末如无以水银代之） 麝香（研） 蟾酥（研） 牛黄（研各一分） 白附
子末（半
上八味，并生用，同研细，面糊丸，如黍米大，每服十丸，薄荷汤下。乳汁亦得。
治小儿无辜疳，面黄发直，时发壮热，饮食不成肌肉。麝香熊胆丸方
麝香（研半两） 熊胆（研二钱） 芦荟（研三分） 胡黄连 黄连（去须各一两） 使
君子（
上七味，捣研为细末，以白面稀糊和丸，如绿豆大，每服十五丸至二十丸，米饮下。
治小儿无辜疳，面黄发直，时时壮热，食不生肌。长肌丸方
胡黄连（半两） 木香 无食子（各一分） 芦荟（研） 麝香（研） 牛黄（研） 黄
柏（去粗
上七味，捣罗四味为末，与三味研者拌匀，滴水和丸，如绿豆大，每服五七丸，温水下
，量儿大小加减。
治小儿无辜疳，发作穗，羸瘦腹胀面黄。蚺蛇胆丸方
蚺蛇胆（去脂炙） 黄芩（去黑心） 枳壳（去瓤面炒） 甘菊花 牛膝（酒浸切焙各
一分）
上七味，捣罗为末，炼蜜和丸，如绿豆大，每服五丸，空腹米饮下，更量儿大小加减。
治小儿诸疳无辜，鼻中出清水，眼上有白晕，或患痢体热，口干生疮，脚肿眼涩，腹中
有虫，喜饮冷水。胡粉散方
胡粉 龙骨末（各一钱匕）
上二味，并炒令黄，以鸡子清调，空心服半钱匕，日二。
Discussion: When infants and children suffer from illness, their faces appear yellow, hair stands straight and is dry, they frequently experience high fever, food intake fails to nourish muscles, lumps form on the head and neck resembling tumors or growths. This condition is contracted due to "Wugu" (a pathogenic factor), hence it is named "Wugu Gan" (Innocent Malnutrition Syndrome). It is caused by infants and children consuming excessive amounts of rich and sweet foods, which stimulates parasites to move due to the sweetness, internally damaging the Spleen Qi and causing dietary irregularities. Treatment should follow the methods used for treating various Gan syndromes.
Loulu Wan Formula: Treats all forms of Wugu Gan in infants and children characterized by yellow emaciation, abdominal pain, Gan dysentery, presence of parasites, and alternating cold and heat sensations.
Dansha Wan Formula
Cinnabar (Dan Sha), Realgar (Xiong Huang) (each 1 fen, ground); Dried Toad (Gan Xama) (one piece, remove head and feet, coat with butter, roast until scorched, then grind into powder); Acorus Tatarinowii Rhizome (Shi Chang Pu); Agrimony Root (Lou Lu) (each 1 liang).
The above six ingredients: Crush and sieve Shi Chang Pu and Lou Lu into powder. Mix with the remaining four ingredients in a mortar, grind uniformly, and sieve again. Form pills using millet rice paste, sized like hemp seeds. Administer two pills per dose, dissolved in rice drink. Take on an empty stomach and in the afternoon, adjusting dosage according to the child's age and size.
Loulu Wan Formula: Treats infantile Wugu Gan with muscle wasting and parasitic infection.
Agrimony Root (Lou Lu) (2 liang, remove root tips); Pig Liver (Bao Gan, remove membrane); Broussonetia Papyrifera Root (Chu Gen) (chopped, each 0.5 liang).
The above three ingredients: Crush and sieve into powder. Bind with refined honey into pills sized like hemp seeds. For children aged 1-2 years, administer 3 pills; for ages 3-4 years, administer 5 pills. Take with warm water before milk or meals, twice daily. If diarrhea is present, take with rice drink instead.
Diyu San Powder: Treats infantile Wugu Gan with dry scalp, distended abdomen, and benefits the brain.
Sanguisorba Officinalis Root (Di Yu) (lightly roasted, 1.5 liang); Snail Shell (Wo Niao Ke) (cleaned of soil); Indigo Naturalis (Qing Dai) (ground, each 1 liang); Moschus (She Xiang); Human Feces Ash (Ren Fen) (burned to ash); Litsea Cubeba Root (Lan Xiang Gen) (burned to ash, text implies processing).
The above eight ingredients: Crush and grind into powder. For infants 50 days old, use a "Yi Zi Bi" measure; for 100 days old, use a slightly larger Yi Zi Bi; for 200 days old, use half a Qian Bi measure. Mix with rice drink and administer at any time. Adjust dosage based on the child's age and size.
Biejia Wan Pill: Treats infantile Wugu Gan.
Tartar Testudinis (Bie Jia) (roasted with vinegar until yellow, remove skirt edge); Coptis Chinensis Rhizome (Huang Lian) (remove stamens); Platycodon Grandiflorus Root (Jie Geng) (stir-fried); Nyctibiidae Droppings (Ye Ming Sha) (each 1 liang); Terminalia Chebula Pericarpium (He Li Le Pi) (two pieces, text implies quantity).
The above seven ingredients: Crush and sieve into powder. Form pills using glutinous rice paste, sized like mung beans. Take seven pills with porridge drink. Also suitable for Gan dysentery, three times daily. Adjust dosage based on the child's age and size.
Xijiao San Powder: Treats all forms of infantile Wugu Gan with emaciation, anorexia, and abdominal distension.
Rhinoceros Horn (Xi Jiao) (shavings); Succinum (Hu Po) (ground); Aloe (Lu Hui) (ground); Acid Pomegranate Southeast Root Bark (Suan Shi Liu Dong Nan Gen Pi) (roasted and chopped); Costus Root (Mu Xiang); Terminalia Chebula Pericarpium (He Li Le Pi); Borneolum Syntheticum (Long Nao) (each 3 liang, text implies quantity).
The above eleven ingredients: Crush and sieve into powder. For children aged 1-2 years, use half a Qian Bi measure; for ages 3-4 years, use one Qian Bi measure. Mix with rice drink and administer at any time. Adjust dosage based on the child's age and size.
Luhui San Powder: Treats infantile Wugu Qi syndrome with stagnation of cold-heat, causing heart and abdominal distension and pain.
Aloe (Lu Hui) (ground); Human Urine Sediment Ash (Ren Zhong Bai) (ground); Toad (Xia Ma) (roasted yellow, each 0.5 liang); Moschus (She Xiang) (ground, 1 fen).
The above four ingredients: Crush and grind finely, then mix thoroughly. Administer one Yi Zi Bi to half a Qian Bi measure per dose, mixed with hot water, at any time, twice daily. After administration, foul matter should be expelled. Adjust dosage based on the child's age and size.
Biejia Tang Decoction: Treats infantile Wugu Gan with thin neck, distended abdomen, and hair forming tufts.
Tartar Testudinis (Bie Jia) (remove skirt edge, roast until scorched); Citrus Reticulata Pericarpium (Chen Ju Pi) (soaked in water, remove white pith, dried); Atractylodes Macrocephala Rhizome (Cang Zhu) (peeled, soaked in rice wash overnight, sliced, dried); Poria Cocos (Chi Fu Ling) (text implies preparation).
The above six ingredients: Coarsely crush and sieve. For children aged 1-2 years, use one Qian Bi measure. Add seven parts water, decoct to four parts, remove dregs, and divide into two warm doses daily. Adjust dosage based on the child's age and size.
Biejia San Powder: Treats infantile Wugu Gan.
Tartar Testudinis (Bie Jia) (remove skirt edge, roast with vinegar until scorched); Terminalia Chebilla Fruit (He Li Le) (remove pit); Atractylodes Macrocephala Rhizome (Cang Zhu) (peeled, soaked in rice wash, sliced, dried); Costus Root (Mu Xiang); Poria Cocos (Chi Fu Ling) (remove black skin, text implies quantity).
The above six ingredients: Crush and sieve into powder. For children aged 1-2 years, use half a Qian Bi measure. Mix with hot water. Take before meals, twice daily. Adjust dosage based on the child's age and size.
Dansha San Powder: Treats infantile Wugu Gan dysentery.
Cinnabar (Dan Sha) (ground); Clove (Ding Xiang) (each 0.5 liang); White Horse Night Eye (Bai Ma Ye Yan) (1 fen, lightly stir-fried).
The above three ingredients: Crush and grind into powder. On an empty stomach, mix half a Qian Bi measure with well water (Jing Hua Shui). Follow with Zhi Gan San.
Zhi Gan San Powder: Treats infantile Wugu Gan.
Pheasant Liver (Zhi Gan) (one piece; if dry, crush; if fresh, roast and grind into powder).
The above single ingredient: Divide into three doses. Immediately after taking Dansha San, take one dose of this powder, mixed with half a Qian Bi measure of rice drink.
Wo Niao Jian Decoction: Treats infantile Wugu Gan.
Snail Shell (Wo Niao Ke) (seven pieces, preferably old dead ones with thin, yellowish-white shells).
The above single ingredient: Clean thoroughly, ensuring no dust remains. Drain and place inside the shell with butter and honey. Contain in a porcelain cup, seal the top with paper, and steam over rice cooking. Once done, sit in the steamer, add rice, and steam again until cooked. Grind the contents finely until watery/starchy. Administer gradually throughout the day, finishing within one day.
Xionghuang Wan Pill: Treats children under ten years old down to newborns hundred days old, addressing epilepsy, heat, Wugu, etc.
Realgar (Xiong Huang); Cinnabar (Dan Sha); Calculus Bovis (Niu Huang); Moschus (She Xiang); Gypsum Fibrosum (Shi Gao) (all ground fine); Prunus Persica Kernel (Rui Ren) (skin removed); Kansui Radix (Gan Sui) (lightly stir-fried); Oyster Shell (Mu Li) (stir-fried and ground, each 0.5 liang, text implies quantity).
The above nine ingredients: Crush and grind into powder. Blend with refined honey and knead into pills sized like millet grains. For children aged 1-2 years, administer two pills with rice drink; for ages 3-4 years, three pills. The goal is mild laxative effect. Adjust dosage based on the child's age and size.
Sishen San Powder: Treats infantile Wugu Gan diarrhea.
Toad (Xia Ma) (one piece, roasted); Coptis Chinensis Rhizome (Huang Lian) (remove stamens, ground); Lead Oxide (Qian Dan) (stir-fried, each 0.5 liang); Moschus (She Xiang) (0.5 fen).
The above four ingredients: Finely grind into powder. Administer half a Qian Bi measure per dose, mixed with aged rice drink.
Jiusheng Wan Pill: Treats infantile Wugu Gan with abdominal distension, asthma, flaccid edema of limbs, alternating hot and cold, sudden dysentery, and hard painful abdomen.
Croton Seed (Ba Dou) (remove skin, take kernel 0.5 liang; boil with 1 sheng rice vinegar and 0.5 liang sliced ginger until vinegar is exhausted, take Ba Dou and grind rotten); Realgar (Xiong Huang) (0.5 liang, ground); Cinnabar (Dan Sha) (text implies quantity).
The above three ingredients: Mix and grind uniformly. Form pills using the center of steamed cake soaked in water, sized like yellow millet. Take two pills daily with Shaoyao Decoction.
Liu Lao Wan Pill: Treats infantile Wugu Gan.
Aged Glutinous Rice (Chen Jing Mi) (1 he, stir-fried to remove fire toxicity); Coptis Chinensis Rhizome (Huang Lian) (remove stamens, 1 liang, cut, stir-fried, cooled to remove fire toxicity); Aged Citrus Reticulata Pericarpium (Chen Ju Pi) (remove white pith, 0.5 liang); Dried Ginger (Gan Jiang) (text implies quantity).
The above four ingredients: Crush into powder. Cook with pig bile and flour paste to form pills sized like small beans. Take seven pills per dose with rice drink, at any time.
Jigangzi Wan Pill: Treats infantile Wugu Gan with yellow face, straight dry hair, frequent high fever, and failure of diet to build muscle.
Jigangzi (for powder; if unavailable, substitute Mercury/Shui Yin); Moschus (She Xiang) (ground); Toad Venom (Chan Su) (ground); Calculus Bovis (Niu Huang) (ground, each 1 fen); White Aconite Root (Bai Fu Zi) (powder, 0.5 liang, text implies quantity).
The above eight ingredients: Use raw, grind together finely. Form pills with flour paste, sized like broomcorn millet. Take ten pills per dose with Mint Decoction. Breast milk is also acceptable.
Shexiang Xiondan Wan Pill: Treats infantile Wugu Gan with yellow face, straight dry hair, intermittent high fever, and failure of diet to build muscle.
Moschus (She Xiang) (ground, 0.5 liang); Bear Bile (Xiong Dan) (ground, 2 qian); Aloe (Lu Hui) (ground, 3 fen); Picrorhiza Rhizome (Hu Huang Lian); Coptis Chinensis Rhizome (Huang Lian) (remove stamens, each 1 liang); Quisqualis Fructus (Shi Jun Zi) (text implies quantity).
The above seven ingredients: Crush and grind into fine powder. Bind with thin wheat flour paste into pills sized like mung beans. Take 15-20 pills per dose with rice drink.
Zhangji Wan Pill: Treats infantile Wugu Gan with yellow face, straight dry hair, frequent high fever, and failure of diet to build muscle.
Picrorhiza Rhizome (Hu Huang Lian) (0.5 liang); Costus Root (Mu Xiang); Noogall (Wu Shi Zi) (each 1 fen); Aloe (Lu Hui) (ground); Moschus (She Xiang) (ground); Calculus Bovis (Niu Huang) (ground); Phellodendron Bark (Huang Bo) (remove rough bark, text implies quantity).
The above seven ingredients: Crush four ingredients into powder, mix with the other three ground ingredients. Add drops of water to form pills sized like mung beans. Take 5-7 pills per dose with warm water. Adjust dosage based on the child's age and size.
Ranshe Dan Wan Pill: Treats infantile Wugu Gan with hair forming tufts, emaciation, abdominal distension, and yellow face.
Rattlesnake Gallbladder (Ranshe Dan) (remove fat, roast); Scutellaria Root (Huang Qin) (remove black heart); Aurantium Fruit (Zhi Ke) (remove pulp, stir-fried with flour); Chrysanthemum Morifolium Flower (Gan Ju Hua); Achyranthes Bidentata Root (Niu Xi) (wine-soaked, sliced, dried, each 1 fen).
The above seven ingredients: Crush and sieve into powder. Bind with refined honey into pills sized like mung beans. Take five pills per dose on an empty stomach with rice drink. Adjust dosage based on the child's age and size.
Hufen San Powder: Treats various Gan and Wugu conditions with clear fluid from nose, white halo around eyes, dysentery with fever, dry mouth with sores, swollen feet, gritty eyes, intestinal parasites, and craving for cold water.
Lead Carbonate (Hu Fen); Dragon Bone Powder (Long Gu Mo) (each 1 Qian Bi measure).
The above two ingredients: Stir-fry until yellow. Mix with egg white. Take half a Qian Bi measure on an empty stomach, twice daily.