病源蛊注者，住也，言其病迟滞停住，死，又注易旁人也，蛊者是聚蛇蛊之类，以器皿
盛之，令其自相啖食，余有一个存者为蛊也，而能变化，人有造作钦事之者，以毒害于他，
多于饮食内而行用之，中之者心闷腹痛，其食五脏尽则死，有缓有急，急者仓猝，十数日便
死，缓者延引岁月，游走腹内，常气力羸惫，骨节沉重，发则心腹烦懊而痛，令人所食之物
，亦变化为蛊，渐侵食腑脏尽而死，死则病流注染着旁人，故为蛊注也。（出第二十四卷中）
范汪疗蛊注百病， 瘕积聚，酸削骨肉，大小便不利，猝忤遇恶风，胪胀腹满，淋水转
相注，殚门尽户，延及男女外孙，医所不能疗，更生十七物紫参丸方。
紫参 人参 半夏（洗） 藜芦 代赭 桔梗 白薇 肉苁蓉（各三分） 石膏（一
分） 大黄（一分） 牡蛎（一分熬） 丹参（一分） 虾蟆灰 乌头（炮四分） 野狼毒（一
分）
上药捣筛，蜜和为丸，以饮下如小豆一丸，日三服，老小以意减之，蜂虿所螫，以涂其
上神良。忌羊肉冷水。（一方无虾蟆有干姜四分出第十四卷中）
短剧雄黄丸，疗蛊注，四肢浮肿，肌肤消索，咳逆，腹大如水状，漏泄死后注易家人方
，一名蛊胀方。
雄黄（研） 巴豆 莽草（炙） 鬼臼（各四分） 蜈蚣（三枚炙）
上五味捣筛为末，蜜和，更捣三千杵，药成，密器封之，勿令泄气，宿勿食，服如小豆
一丸，
葱豉粥
集验疗鬼注蛊注，毒瓦斯变化无常，鲛鱼皮散方。
鲛鱼皮（鹊鱼斑皮是） 犀角 麝香（研） 龙骨 丹砂（研） 雄黄（研） 荷叶 鹿
角（炙各一分） 蜈蚣（一枚炙） 椒（一分汗） 干姜（一分） 贝子（十枚） 鸡舌香
（一分）
上十三味捣筛为散，空心酒服一钱匕，日三服。（出第一卷中）
The etiology of *Gu Zhu* (Gu Infestation) refers to the stagnation and immobility of pathogenic factors. The term "stagnation" implies that the disease progresses slowly, while "Zhu" also denotes the transmission of the disease to others. "Gu" refers to the accumulation of venomous creatures such as snakes and insects, placed in a vessel to devour each other until only one survivor remains, which is then called "Gu". This Gu can transform its form. Individuals who create Gu for malicious purposes often administer it through food and drink. Those infected experience chest oppression, abdominal pain, and if the five Zang organs are completely eroded, death ensues. The condition varies in acuity: acute cases develop rapidly, leading to death within ten days; chronic cases drag on over years, with the pathogen wandering within the abdomen. Patients suffer from general weakness, fatigue, and heavy joints. Upon onset, they experience mental restlessness, irritability, and pain. It is believed that ingested food transforms into Gu, gradually consuming the viscera until death. After death, the pathogenic qi flows and infects others, hence the name "Gu Zhu". (From Volume 24)
Fan Wang's treatment for various diseases caused by Gu Zhu, including *Jia Ji Ju* (abdominal masses), emaciation of flesh and bone, difficulty in urination and defecation, sudden exposure to evil wind, abdominal distension, dripping sensations resembling water flow, and the spread of illness throughout households affecting men, women, and grandchildren beyond medical cure, prescribes the Zi Shen Wan (Purple Ginseng Pill) formula consisting of seventeen ingredients.
Zi Shen (Codonopsis Radix or similar, literal: Purple Root), Ren Shen (Ginseng Radix), Ban Xia (Pinelliae Rhizoma, washed), Li Lu (Veratri Rhizoma), Dai Zhe Shi (Haematitum), Jie Geng (Platycodonis Radix), Bai Wei (Cynanchi Atrati Radix), Rou Cong Rong (Cistanche Caulis), each at three fen; Shi Gao (Gypsum Fibrosum) at one fen; Da Huang (Rhei Radix et Rhizoma) at one fen; Mu Li (Ostreae Concha, calcined) at one fen; Dan Shen (Salviae Miltiorrhizae Radix) at one fen; Xia Ma Hui (Bufo Skin Ash); Wu Tou (Aconiti Lateralis Radix Praeparata, processed) at four fen; Ye Lang Du (Stellerae Radix) at one fen.
Pulverize and sieve the above herbs, mix with honey to form pills. Take one pill the size of a small bean, dissolved in water, three times daily. Dosage for elderly and children should be adjusted accordingly. For stings from bees or scorpions, apply topically for excellent results. Avoid mutton and cold water. (Another version excludes Bufo Skin Ash and includes Gan Jiang [Zingiberis Rhizoma] at four fen; From Volume 14).
The Xiong Huang Wan (Realgar Pill) from the *Duan Ju* text treats Gu Zhu characterized by edema of the four limbs, wasting of skin and muscle, cough and counterflow qi, abdominal distension resembling water retention, leakage/diarrhea, and the transmission of disease to family members after death. This formula is also known as the Gu Zhang (Gu Distension) Formula.
Xiong Huang (Realgar, pulverized), Ba Dou (Crotonis Fructus), Mang Cao (Illicii Anisi Stellati Herba, roasted), Gui Jiu (Podophylli Peltati Rhizoma), each at four fen; Wu Gong (Scolopendra, three pieces, roasted).
Pulverize and sieve the five herbs into powder, mix with honey, and pound for three thousand strokes. Seal tightly in a container to prevent gas leakage. Fast overnight before administration. Take one pill the size of a small bean.
Scallion and Fermented Soybean Porridge
The Jiao Yu Pi San (Shark Skin Powder) from the *Ji Yan* text treats Gui Zhu and Gu Zhu, where toxic vapors change unpredictably.
Jiao Yu Pi (Skin of Shark/Seabream, specifically Que Yu Ban Pi), Xi Jiao (Rhino Horn, substituted typically with Buffalo Horn in modern practice but translated literally here), She Xiang (Moschus, pulverized), Long Gu (Fossilia Ossis Mastodi et Scapulae), Dan Sha (Cinnabaris, pulverized), Xiong Huang (Realgar, pulverized), He Ye (Nelumbinis Folium), Lu Jiao (Cervi Cornus Pantotrichum, roasted, each one fen), Wu Gong (Scolopendra, one piece, roasted), Jiao (Zanthoxyli Pericarpium, one fen), Gan Jiang (Zingiberis Rhizoma, one fen), Bei Zi (Concha Meretricis et Cyclinae, ten pieces), Ji She Xiang (Cardamomi Semen, one fen).
Pulverize and sieve the thirteen herbs into powder. Take one qian bi (a traditional measure) with wine on an empty stomach, three times daily. (From Volume 1).