夫久疟者。皆由伤暑及伤风所为也。热盛之时。发汗吐下过度。脏腑空虚。荣卫伤损。
邪气伏藏。所以引日不瘥。故止而复作。一岁发至三岁。或连日发不解。胁下有痞。治之。
不得
便自
（缺方名及主治）
野狐肝（一两腊月者） 雄黄（一两细研） 阿魏（半两） 朱砂（半两细研） 猢狲
头骨（一
两生用） 天灵盖（一两生用） 麝香（半两细研）
上件药。捣罗为末。入研了药。都研令匀。五月五日午时。炼蜜和丸。如梧桐子大。男
左女右。以青绢系一丸于中指上。嗅之。其病即瘥。难可者。更以醋汤服一服。
治久疟不瘥。羸瘦无力。寒热不能饮食。宜服此方。
乌梅内（一两微炒） 恒山（一两锉） 附子（一两炮裂去皮脐） 虎头骨（一两半涂
酥炙黄）
桃仁（半
两）
肉苁蓉（一
上件药。捣罗为末。炼蜜和捣三五百杵。丸如梧桐子大。每日空心。以粥饮下三十丸。
晚食前再服。
治疟累年不瘥者。宜用此方。
安息香（一两） 白芥子（一两） 桃奴（二七枚） 道人头（一两）
上件药。捣罗为末。炼蜜和捣百余杵。丸如梧桐子大。但于发时。男左女右。手把一丸
。永瘥。
治远年劳疟不瘥。宜服此方。
恒山（半两锉） 附子（半两炮裂去皮脐） 薄荷根（半两） 麝香（一钱细研） 阿
魏（一分
面裹煨面熟为度）
上件药。捣罗为末。和阿魏麝香。都研令匀。炼蜜和丸。如梧桐子大。每于食前。以温
酒下十五丸。
治疟久不瘥。神效方。
蜘蛛（五枚大者去脚研如膏） 蛇蜕皮（一条全者烧灰） 蝙蝠（一枚炙令微焦） 麝
香（半
两细研） 鳖甲（一枚涂醋炙令黄去裙 ）
上件药。捣罗为末。入研了药令匀。五月五日午时。以蜘蛛膏。入炼蜜。同和。丸如麻
子大。每服空心。以温酒下五丸。小儿以茶下二（三）丸。
治疟久不瘥。或止或发。继月连年。诸药无效者。宜用此方。
狗头骨（半两） 鼠头骨（半两） 蛇头（一枚） 牛头骨（半两） 虎头骨（半两） 兔
头骨（
半两） 狸头骨（半两）
两） 鳖
甲（半两） 龟甲（半
香（半两
细研）
上件药。并生用。捣罗为末。入研了药。更研令匀。以软饭和丸。如鸡头实大。以青绢
裹。男左女右。手中指上系一丸。如未定。即以醋茶下一丸。
又方。
川大黄（一两） 砒霜（半两） 绿豆粉（半两） 阿魏（半两） 麝香（半两）
上件药。都细研令匀。以软饭和丸。如小豆大。以醋茶下一丸。当吐即瘥。
治疟久不瘥。或发或止。淹延岁月。诸药无效。宜用此方。
朱砂（一分细研） 雄黄（一分细研） 麝香（一分细研） 砒霜（一两细研） 天灵
盖（一枚
生用） 猢狲头骨（一分生用） 绿豆（一两） 虎头骨〔一斤（分）生用〕
上件药。捣罗为末。入研了药令匀。炼蜜和丸。如梧桐子大。男左女右。手把一丸便睡
睡觉便瘥。
治久疟神效方。
狐粪（一两末） 雄黄（一两） 阿魏（一分） 黄丹（一两） 朱砂（一两） 丁香
（一分末）
麝香（一分）
上件药。都研令细。以醋煮面糊和丸。如鸡头实大。以绯帛裹一丸。男左女右。系在臂
上。即瘥。
又方。
砒霜（半两） 阿魏（一分） 川大黄（半两锉微炒） 朱砂（一分细研） 绿豆（二
十八粒）
上件药。捣罗为末。入研了药令匀。用醋饭和为丸。如梧桐子大。临发前。以冷水下一
丸。神效。忌食热物。
又方。
道人头（一两） 雄黄（三分细研） 砒霜（一分细研） 香豉（一合炙干） 荷叶〔三
（七）
枚〕 甘草（三分生用）
上件药。捣罗为末。入研了药令匀。炼蜜和丸。梧桐子大。发前。以冷醋汤下一丸。
立效。忌食热物。
又方。
虎睛（一对生用） 狗胆汁（一枚） 天灵盖（一分生用） 麝香（半钱细研）
上件药。捣罗为末。入麝香研匀。以狗胆汁和丸。如梧桐子大。以绯帛裹一丸。男左女
右。手中指上系之。如患多时者。生姜汤下一丸。
又方。
熊胆 五灵脂 恒山（锉） 野鸡粪（雄者各半分）
上件药。捣罗为末。以醋煮面糊和丸。如黑豆大。正发时。以冷水下一丸。
又方。
虾蟆（大者一枚生用） 砒黄（一分） 黄丹（一分）
上件药。二味。纳在虾蟆腹中。用盐泥固济。烧令通赤。取出。研为末。用醋煮面糊和
丸。如梧桐子大。每服。以冷醋汤下三丸。忌食热物。
Chronic malaria is caused by injury from summer-heat and wind-cold. During the period of intense heat, if sweating, vomiting, or purging are excessive, the zang-fu organs become empty, and Ying (Nutritive) and Wei (Defensive) Qi are damaged.
Pathogenic factors lie dormant, so the illness persists for a long time without recovery. Thus, symptoms stop and then recur, occurring annually for up to three years, or continuing daily without resolution, with masses under the hypochondrium. In treatment,
(The name of the prescription and its indications are missing here)
Vulpis Hepatis (Fox Liver, 1 liang, collected in the twelfth lunar month) Xionghuang (Realgar, 1 liang, finely ground) Awei (Ferulae Resina, 0.5 liang) Zhusha (Cinnabar, 0.5 liang, finely ground) Macaca Capitis Os (Monkey Skull Bone, 1 liang, raw use) Tianlinggai (Human Calvaria, 1 liang, raw use) Shexiang (Musk, 0.5 liang, finely ground)
The above medicines are crushed, sieved into powder, mixed with the already ground medicines, and thoroughly blended. At noon on the fifth day of the fifth lunar month, blend with refined honey to form pills the size of Sophora japonica seeds. Males hold one pill in the left hand, females in the right hand, tie it to the middle finger with green silk, and inhale its odor; the disease will heal. For difficult cases, take another dose with vinegar water.
For chronic malaria that does not resolve, accompanied by emaciation, weakness, alternating chills and fever, and inability to eat, this prescription is suitable.
Wumei (Fructus Mume, 1 liang, slightly stir-fried) Hengshan (Radix Dichroae, 1 liang, sliced) Fuzi (Radix Aconiti Lateralis Preparata, 1 liang, processed until cracked, skin and umbilicus removed) Huto Gu (Tigris Ossis Capitis, 1.5 liang, coated with butter and roasted until yellow) Taoren (Semen Persicae, 0.5 liang) Roushou Rong (Cibotii Rhizoma, 1 liang)
The above medicines are crushed, sieved into powder, blended with refined honey, and pounded 300–500 times to form pills the size of Sophora japonica seeds. Take 30 pills on an empty stomach daily with porridge drink. Take another dose before evening meal.
For malaria persisting for many years, this prescription is suitable.
Anshixiang (Styrax, 1 liang) Baijiezi (Sisymbrii Semen, 1 liang) Taonuo (Ramulus Pruni Persicae, 14 pieces) Daoren Tou (Buddhist Monk's Calvaria, 1 liang)
The above medicines are crushed, sieved into powder, blended with refined honey, and pounded over 100 times to form pills the size of Sophora japonica seeds. Simply hold one pill in the hand during attacks—males in the left hand, females in the right—and the disease will be permanently cured.
For remote chronic malaria (Lao Nue) that does not resolve, this prescription is suitable.
Hengshan (Radix Dichroae, 0.5 liang, sliced) Fuzi (Radix Aconiti Lateralis Preparata, 0.5 liang, processed until cracked, skin and umbilicus removed) Bohe Gen (Radix Menthae, 0.5 liang) Shexiang (Musk, 1 qian, finely ground) Awei (Ferulae Resina, 1 fen, wrapped in dough and baked until dough is cooked)
The above medicines are crushed, sieved into powder, and blended with Awei and Shexiang until uniform. Blend with refined honey to form pills the size of Sophora japonica seeds. Take 15 pills before meals with warm wine.
A miraculous formula for chronic malaria that does not resolve.
Zhi Zhu (Aranea, 5 large ones, legs removed and ground into paste) Tuipí (Ophichthidis Cutis Coriacea, 1 whole piece, burned to ash) Bianfu (Vespertilionis Carcass, 1 piece, roasted until slightly charred) Shexiang (Musk, 0.5 liang, finely ground) Biejia (Testudinis Carapax et Plastrum, 1 piece, coated with vinegar and roasted until yellow, skirt edges removed)
The above medicines are crushed, sieved into powder, mixed with the already ground medicines until uniform. At noon on the fifth day of the fifth lunar month, mix with Aranea paste and refined honey to form pills the size of Sesamum indicum seeds. Take 5 pills on an empty stomach with warm wine. Children take 2–3 pills with tea.
For chronic malaria that does not resolve, or stops and recurs, lasting months and years, where all other medicines are ineffective, this prescription is suitable.
Goutou Gu (Canis Cranium Os, 0.5 liang) Shutou Gu (Rattus Cranium Os, 0.5 liang) Shetou (Coluber Capitius, 1 piece) Niutou Gu (Bovis Cranium Os, 0.5 liang) Hutou Gu (Tigris Cranium Os, 0.5 liang) Toutou Gu (Leporis Cranium Os, 0.5 liang) Litou Gu (Vulpis Cranium Os, 0.5 liang) Biejia (Testudinis Carapax et Plastrum, 0.5 liang) Guijia (Chelonis Carapax et Plastrum, 0.5 liang) Shexiang (Musk, 0.5 liang, finely ground)
All above medicines are used raw, crushed, sieved into powder, mixed with the already ground medicines, and ground again until uniform. Blend with soft rice to form pills the size of Euryale ferox seeds. Wrap in green silk, males hold in left hand, females in right hand, tie to middle finger. If the condition is unstable, take one pill with vinegar tea.
Another prescription.
Dahuang (Rhei Radix et Rhizoma, 1 liang) Pishuang (Arsenici Sulfidum Rubrum, 0.5 liang) Lüdou Fen (Phaseoli Volubilis Semen Pulvis, 0.5 liang) Awei (Ferulae Resina, 0.5 liang) Shexiang (Musk, 0.5 liang)
All above medicines are finely ground until uniform. Blend with soft rice to form pills the size of Phaseolus angularis seeds. Take one pill with vinegar tea. Vomiting should occur, and the disease will heal.
For chronic malaria that does not resolve, or recurs or stops, dragging on for years, where all other medicines are ineffective, this prescription is suitable.
Zhusha (Cinnabar, 1 fen, finely ground) Xionghuang (Realgar, 1 fen, finely ground) Shexiang (Musk, 1 fen, finely ground) Pishuang (Arsenici Sulfidum Rubrum, 1 liang, finely ground) Tianlinggai (Human Calvaria, 1 piece, raw use) Macaca Capitis Os (Monkey Skull Bone, 1 fen, raw use) Lüdou (Phaseoli Volubilis Semen, 1 liang) Hutou Gu (Tigris Cranium Os, 1 jin [fen], raw use)
The above medicines are crushed, sieved into powder, mixed with the already ground medicines until uniform. Blend with refined honey to form pills the size of Sophora japonica seeds. Males hold one pill in the left hand, females in the right hand, and go to sleep; upon waking, the disease will heal.
A miraculous formula for chronic malaria.
Hufen (Vulpis Faeces, 1 liang, powdered) Xionghuang (Realgar, 1 liang) Awei (Ferulae Resina, 1 fen) Huangdan (Minium, 1 liang) Zhusha (Cinnabar, 1 liang) Dingxiang (Caryophylli Flos, 1 fen, powdered) Shexiang (Musk, 1 fen)
All above medicines are ground extremely fine. Blend with vinegar-boiled flour paste to form pills the size of Euryale ferox seeds. Wrap one pill in red silk, males hold in left hand, females in right hand, tie to arm; the disease will heal.
Another prescription.
Pishuang (Arsenici Sulfidum Rubrum, 0.5 liang) Awei (Ferulae Resina, 1 fen) Dahuang (Rhei Radix et Rhizoma, 0.5 liang, sliced and slightly stir-fried) Zhusha (Cinnabar, 1 fen, finely ground) Lüdou (Phaseoli Volubilis Semen, 28 grains)
The above medicines are crushed, sieved into powder, mixed with the already ground medicines until uniform. Blend with vinegar-rice to form pills the size of Sophora japonica seeds. Before onset, take one pill with cold water. Miraculous effect. Avoid hot foods.
Another prescription.
Daoren Tou (Buddhist Monk's Calvaria, 1 liang) Xionghuang (Realgar, 3 fen, finely ground) Pishuang (Arsenici Sulfidum Rubrum, 1 fen, finely ground) Xiangchi (Fermentatio Sojae Preparata, 1 he, roasted dry) Heye (Nelumbinis Folium, 3–7 pieces) Gancao (Glycyrrhizae Radix et Rhizoma, 3 fen, raw use)
The above medicines are crushed, sieved into powder, mixed with the already ground medicines until uniform. Blend with refined honey to form pills the size of Sophora japonica seeds. Before onset, take one pill with cold vinegar water. Immediate effect. Avoid hot foods.
Another prescription.
Hu Jing (Tigris Bulbus, 1 pair, raw use) Gou Danzhi (Canis Bile, 1 unit) Tianlinggai (Human Calvaria, 1 fen, raw use) Shexiang (Musk, 0.5 qian, finely ground)
The above medicines are crushed, sieved into powder, mixed with Shexiang and ground until uniform. Blend with Canis Bile to form pills the size of Sophora japonica seeds. Wrap one pill in red silk, males hold in left hand, females in right hand, tie to middle finger. For long-standing cases, take one pill with ginger water.
Another prescription.
Xiong Dan (Ursi Bile) Wulingzhi (Trogopterori Excrement) Hengshan (Radix Dichroae, sliced) Yeji Fen (Phasianus Colchicus Faeces, male, each half part)
The above medicines are crushed, sieved into powder, blended with vinegar-boiled flour paste to form pills the size of Glycine max seeds. At the exact time of onset, take one pill with cold water.
Another prescription.
Xama (Bufo, 1 large one, raw use) Pi Huang (Arsenic compound, 1 fen) Huangdan (Minium, 1 fen)
Place the two medicines inside the Bufo abdomen, seal firmly with salt mud, and burn until red-hot. Remove, grind into powder, and blend with vinegar-boiled flour paste to form pills the size of Sophora japonica seeds. Take 3 pills per dose with cold vinegar water. Avoid hot foods.