夫身体发疮。皆是风热所为。然虚者易伤于邪。若重触风寒。则冷气入于疮。令血涩不
行。其疮则顽冷不知痛痒。亦经久难瘥。名为冷疮也。
治冷疮久不瘥。芜荑散方。
芜荑（一两微炒） 藜芦（一两去芦头） 薰黄（半两） 青矾（半两） 雄黄（半两
细研） 苦
参（三分锉） 附子（三分炮裂去皮脐）
上件药。捣罗为末。先以温水洗疮去痂。干拭。以生油调涂之。
治冷疮。发歇疼痛。脓水不止。生肌乌贼鱼骨散方。
乌贼鱼骨（一两烧令烟尽） 黄连（一分去须） 槟榔（一枚） 诃黎勒皮（一分） 白
龙骨（
一钱半） 赤石脂 麝香（一钱）
上件药。捣细罗为散。于乳钵内。入麝香龙骨赤石脂相和。研令匀。每用时。先暖盐浆
水洗疮。拭令干后。以散敷。日二用之。
治冷疮不瘥。神效槟榔散方。
槟榔（半两） 甘草（半两锉） 郁金（半两） 木香（半两） 黄连（半两去须） 麝
香（一分
细研）
上件药。捣细罗为散。研和令匀。先取砒霜少许安疮上。用生油调散敷之。有脓水。即
干掺于上如法系裹。日再换之。
治冷疮。疼痛不止方。
蛇床子（一两） 乳香（半两） 薤白（临时）
上二味。捣罗为末。入薤白捣。看稀稠得所。可疮上贴之。
治积年风冷疮疼痛。宜用此方。
麝香〔二（一）分〕 乳香（一分） 龙骨（一分）
上件药。都细研。用黄蜡。临时看疮口大小。于锅内熔蜡。如软面。入前药相和。热用
在疮口上。不过三两上瘥。
治冷疮。日夜发歇疼痛。附子散方。
附子（半两炮裂去皮脐） 川椒（一分去目） 白矾（三分烧令汁尽细研） 腻粉（二
钱） 雄
黄（一分细研）
上件药。附子椒二味。捣罗为末。次入白矾腻粉雄黄。相和令匀。每使时。以清麻油调
令得所。以敷疮上。日二换之。
又方。
龙骨（一两烧灰） 蜂窠（一两烧灰） 蛇床子（半两末）
上件药。都研令细。以生油调涂。日二换之。
Whenever sores appear on the body, they are caused by Wind-Heat pathogenic factors. However, individuals with deficiency are prone to invasion by external pathogens. If severely exposed to Cold-Wind again, Cold Qi enters the sore, causing blood stasis and impaired circulation. Consequently, the sore becomes hard, cold, and insensate (loss of pain and itch sensation), and it is difficult to heal over a long period. This condition is named "Cold Sore" (Leng Chuang).
For treating chronic Cold Sores that fail to heal, use Wuyi San Powder Formula.
Herbs: Myristica Seed (Wuyi, 1 liang, lightly stir-fried), Veratrum Rhizome (Lilu, 1 liang, remove rhizome head), Realgar (Xunhuang, 0.5 liang), Green Vitriol (Qingfan, 0.5 liang), Realgar (Xionghuang, 0.5 liang, finely ground), Sophora Root (Kushen, 3 fen, chopped), Aconite Root (Fuzi, 3 fen, processed until cracked, skin and umbilical scar removed).
Preparation and Administration: Pound the above herbs and sieve them into powder. First, wash the sore with warm water to remove scabs, then dry thoroughly. Mix the powder with raw sesame oil and apply to the affected area.
For treating Cold Sores characterized by intermittent pain and continuous purulent discharge, promoting tissue regeneration, use Oyster Shell Powder Formula (Wuzeiyu Gu San).
Herbs: Cuttlefish Bone (Wuzeiyu Gu, 1 liang, burned until smoke ceases), Coptis Rhizome (Huanglian, 1 fen, remove roots), Areca Nut (Binglang, 1 piece), Chebula Fruit Peel (Helile Pi, 1 fen), White Dragon Bone (Bailonggu, 1.5 qian), Red Kaolin (Chishizhi), Musk (Shexiang, 1 qian).
Preparation and Administration: Pound the above herbs and sieve them into a fine powder. In a mortar, mix Musk, Dragon Bone, and Red Kaolin, grinding them evenly. For each application, first wash the sore with warm saline solution, dry it, and then apply the powder. Use twice daily.
For treating persistent Cold Sores, use the Highly Effective Areca Nut Powder Formula (Shenxiao Binglang San).
Herbs: Areca Nut (Binglang, 0.5 liang), Licorice Root (Gancao, 0.5 liang, chopped), Turmeric Tuber (Yujin, 0.5 liang), Aucklandia Root (Muxiang, 0.5 liang), Coptis Rhizome (Huanglian, 0.5 liang, remove roots), Musk (Shexiang, 1 fen, finely ground).
Preparation and Administration: Pound the above herbs and sieve them into a fine powder, mixing evenly. Place a small amount of Arsenic Trioxide (Pishuang) directly onto the sore, then cover with the powder mixed with raw sesame oil. If there is purulent discharge, sprinkle the dry powder directly onto the lesion and bandage as usual. Change the dressing twice daily.
For treating Cold Sores with unceasing pain.
Herbs: Cnidium Fruit (Shechuangzi, 1 liang), Frankincense (Ruxiang, 0.5 liang), Shallot Bulb (Xiebai, appropriate amount).
Preparation and Administration: Pound the first two herbs into powder, add Xiebai, and pound together until the consistency is suitable for topical application. Apply to the sore.
For treating chronic Wind-Cold Sores with pain accumulated over years, this formula is recommended.
Herbs: Musk (Shexiang, 2 fen or 1 fen), Frankincense (Ruxiang, 1 fen), Dragon Bone (Longgu, 1 fen).
Preparation and Administration: Finely grind all the above herbs. Use yellow beeswax; determine the amount based on the size of the sore. Melt the wax in a pot until it resembles soft dough, mix in the herbal powder, and apply while hot to the sore. Healing can be expected within no more than three liang of treatment.
For treating Cold Sores with intermittent pain occurring day and night, use Aconite Powder Formula (Fuzi San).
Herbs: Aconite Root (Fuzi, 0.5 liang, processed until cracked, skin and umbilical scar removed), Sichuan Pepper (Chuanjiao, 1 fen, remove seeds/eyes), Alum (Baifan, 3 fen, burned until liquid evaporates, finely ground), Calomel (Nifen), Realgar (Xionghuang, 1 fen, finely ground).
Preparation and Administration: Pound Fuzi and Chuanjiao into powder. Then add Baifan, Nifen, and Xionghuang, mixing evenly. For each application, mix with pure sesame oil to an appropriate consistency and apply to the sore. Change twice daily.
Another Formula.
Herbs: Dragon Bone (Longgu, 1 liang, burned to ash), Beehive (Fengke, 1 liang, burned to ash), Cnidium Fruit (Shechuangzi, 0.5 liang, powdered).
Preparation and Administration: Grind all the above herbs finely. Mix with raw sesame oil and apply. Change twice daily.