夫时气二日。阳明受病。阳明主于肌肉。其脉络于鼻。入于目。故得病二日肉热鼻干。
不得眠也。夫诸阳在表。表始受病。故可摩膏火灸。发汗而愈也。
治时气二日。头痛壮热。宜服水解散方。
麻黄（二两去根节） 川大黄（一两锉碎微炒） 黄芩（一两） 桂心（一两） 甘草
（一两炙
微赤锉） 赤芍药（一两）
上件药。捣细罗为散。每服。不计时候。以温水调下二钱。良久再服。未服药前。先以
热汤淋浴后。便服此药。衣盖取汗。
治时气二日。壮热。头疼。宜服此方。
甘草（一两炙微赤锉） 生姜（三分） 栝蒌（一颗大者取瓤去子于碗内盛之）
上件药。先将生姜甘草。用无灰酒一大盏。煎取六分。去滓。热入栝蒌碗中绞取汁。不
计时候。分温二服。
治时气二日。壮热憎寒。头痛。腰脊强重。宜服柴胡散方。
柴胡（一两去苗） 麻黄（一两去根节） 葛根（三分锉） 桂心（三分） 甘草（一
分炙微赤
锉）
上件药。捣罗为散。每服四钱。以水一中盏。入豉五十粒。薄荷二七叶。煎至六分。去
滓。不计时候。先吃粥少许。后以热水淋浴。然后服此药。衣覆取汗。
治时气二日。头痛。背强。身热恶寒。宜服栀子散方。
栀子仁（一两） 黄芩（一两） 石膏〔一（二）两〕 杏仁（一两汤浸去皮尖双仁麸
炒微黄）
葛根（一两锉） 甘草（半两炙微赤锉）
上件药。捣罗为散。每服五钱。以水一大盏。入葱白二茎。豉五十粒。煎至五分。去滓
。不计时候。热服。衣覆取汗。
治时气二日。头痛。背强。心烦壮热。宜服葛根散方。
葛根（锉） 麻黄（去根节） 犀角屑（以上各一两）
上件药。捣罗为散。每服五钱。以水一大盏。入生姜半分。枣三枚。煎至五分。去滓。
不计时候。热服。衣覆取汗。
On the second day of a seasonal epidemic disease (Shi Qi Bing), the pathogen affects the Yangming channel. The Yangming channel governs the muscles, its collaterals connect to the nose, and it enters the eyes. Therefore, on the second day of illness, symptoms include muscle heat, dryness of the nose, and insomnia. Since all Yang channels are located at the exterior, and the exterior is just beginning to be affected by the pathogen, treatment can involve applying medicated ointments or moxibustion to induce sweating and achieve recovery.
For the second day of a seasonal epidemic disease, presenting with headache and high fever, the Shuijie San (Water-Resolving Powder) is indicated.
Ingredients: Ephedrae Herba (Mahuang, 麻黄) (2 liang, remove roots and nodes), Rheum Radix et Rhizoma (Chuan Dahuang, 川大黄) (1 liang, cut into small pieces and lightly stir-fried), Scutellariae Radix (Huangqin, 黄芩) (1 liang), Cinnamomi Cortex (Guixin, 桂心) (1 liang), Glycyrrhizae Radix et Rhizoma (Gancao, 甘草) (1 liang, honey-fried until slightly red and cut into small pieces), Paeoniae Rubra Radix (Chishaoyao, 赤芍药) (1 liang).
Preparation and Administration: Pulverize the above ingredients through a fine sieve to make a powder. Take 2 qian each time, at any time, mixed with warm water. Administer another dose after some time. Before taking the medicine, take a hot shower first, then immediately take this medicine, and cover the body with clothing to induce sweating.
For the second day of a seasonal epidemic disease, presenting with high fever and headache, this formula is indicated.
Ingredients: Glycyrrhizae Radix et Rhizoma (Gancao, 甘草) (1 liang, honey-fried until slightly red and cut into small pieces), Zingiberis Rhizoma Recens (Shengjiang, 生姜) (3 fen), Trichosanthis Fructus (Gualou, 栝蒌) (one large fruit, take the pulp, remove seeds, and place in a bowl).
Preparation and Administration: First, decoct the ginger and licorice root in one large cup of unadulterated wine until reduced to six-tenths. Strain the dregs. Pour the hot liquid into the bowl containing the trichosanthis pulp, squeeze to extract the juice. Take divided into two warm doses, at any time.
For the second day of a seasonal epidemic disease, presenting with high fever, aversion to cold, headache, and stiffness/heaviness of the waist and spine, the Chaihu San (Bupleurum Powder) is indicated.
Ingredients: Bupleuri Radix (Chaihu, 柴胡) (1 liang, remove sprouts), Ephedrae Herba (Mahuang, 麻黄) (1 liang, remove roots and nodes), Puerariae Radix (Gegen, 葛根) (3 fen, cut into small pieces), Cinnamomi Cortex (Guixin, 桂心) (3 fen), Glycyrrhizae Radix et Rhizoma (Gancao, 甘草) (1 fen, honey-fried until slightly red and cut into small pieces).
Preparation and Administration: Pulverize the above ingredients through a sieve to make a powder. Take 4 qian each time. Decoct with one medium cup of water, adding 50 grains of Sojae Preparata (Douchi, 豆豉) and 14 leaves of Menthae Haplocalycis (Bohe, 薄荷), until reduced to six-tenths. Strain the dregs. At any time, eat a little porridge first, then take a hot shower, followed by administering this medicine. Cover the body with clothing to induce sweating.
For the second day of a seasonal epidemic disease, presenting with headache, back stiffness, body heat, and aversion to cold, the Zhizi San (Gardenia Powder) is indicated.
Ingredients: Gardeniae Fructus (Zhizi Ren, 栀子仁) (1 liang), Scutellariae Radix (Huangqin, 黄芩) (1 liang), Gypsum Fibrosum (Shigao, 石膏) (1 or 2 liang), Pruni Semen Armeniacae Amarum (Xingren, 杏仁) (1 liang, soaked in water, remove skin and tips, discard double-kernel ones, stir-fried with bran until slightly yellow), Puerariae Radix (Gegen, 葛根) (1 liang, cut into small pieces), Glycyrrhizae Radix et Rhizoma (Gancao, 甘草) (0.5 liang, honey-fried until slightly red and cut into small pieces).
Preparation and Administration: Pulverize the above ingredients through a sieve to make a powder. Take 5 qian each time. Decoct with one large cup of water, adding 2 stems of Allii Fistulosi Bulbus (Congbai, 葱白) and 50 grains of Sojae Preparata (Douchi, 豆豉), until reduced to five-tenths. Strain the dregs. Take hot at any time, covering the body with clothing to induce sweating.
For the second day of a seasonal epidemic disease, presenting with headache, back stiffness, mental restlessness, and high fever, the Gegen San (Kudzu Powder) is indicated.
Ingredients: Puerariae Radix (Gegen, 葛根) (cut into small pieces), Ephedrae Herba (Mahuang, 麻黄) (remove roots and nodes), Cornu Bubali (Xijiao, 犀角) (each 1 liang).
Preparation and Administration: Pulverize the above ingredients through a sieve to make a powder. Take 5 qian each time. Decoct with one large cup of water, adding 0.5 fen of Zingiberis Rhizoma Recens (Shengjiang, 生姜) and 3 dates, until reduced to five-tenths. Strain the dregs. Take hot at any time, covering the body with clothing to induce sweating.