夫时气发狂者。由热毒瓦斯盛。则弃衣而走。登高而歌。或不食数日。逾垣上屋。非是素
所能
盛于
治时气热毒攻心。面目俱赤。发狂。不识人。宜服栀子散方。
栀子仁 葳蕤 茯神 麦门冬（去心） 川升麻 知母 犀角屑 沙参（去芦头） 黄
芩
川大黄（锉碎微炒） 甘草（炙微赤锉以上各一两）
上件药。捣筛为散。每服四钱。以水一中盏。煎至六分。去滓。不计时候。温服。
治时气心神狂躁。言语无度。宜服此方。
鸡子（二枚取清） 白蜜（半合） 生地黄汁（一合） 川大黄（半两锉碎微炒杵末）
上件药。相和令匀。顿服之。以利为度。
治时气大热。心狂欲走。宜服白藓皮散方。
白藓皮（一两半） 大青 羚羊角屑 玄参 栀子仁 子芩 川大黄（炙微赤锉） 地
骨皮
（以上各三分）
上件药。捣筛为散。每服五钱。以水一大盏。煎至五分。去滓。不计时候。温服。
又方。
麦门冬（三两去心） 杏仁〔一（二）两汤浸去皮尖双仁麸炒微黄〕 甘草（一两炙微
赤锉）
白藓皮（二两） 生干地黄（二两） 黄芩（一两）
上件药。捣筛为散。每服五钱。以水一大盏。入葱白二茎。煎至五分。去滓。不计时候
。温服之。
治时气热毒攻心。言语不定。心狂烦乱。不得睡卧。宜服犀角散方。
犀角屑 龙齿 子芩 沙参（去芦头） 葳蕤 麦门冬（去心） 川升麻 赤茯苓 赤
芍药
杏
甘
草（
上件药。捣筛为散。每服五钱。以水一大盏。煎至五分。去滓。不计时候。温服之。
治时气发狂。叫呼。不识人。宜服此方。
黄连（一两去须） 秦艽（一两去苗） 栀子仁（一两） 铁粉（二两）
上件药。捣细罗为散。每服不计时候。以新汲水调下二钱。
又方。
栀子仁（半两） 豉（一合） 葱白（五茎）
上件药。以水二大盏。煎至一盏。去滓。分温二服。
治时气发狂方。
寒水石（一两） 马牙硝（一两）
上件药。细研如面。不计时候。以新汲水调下一钱。
又方。
秦艽（半两去苗） 大青（半两） 甘草（半两炙微赤锉）
上件药。捣细罗为散。不计时候。以生地黄汁。调下二钱服。
治时气热盛癫狂。或时昏沉方。
寒水石（半两） 朱砂（一分） 铅霜（一分）
上件药都研如粉。以软饭和丸。如梧桐子大。每服不计时候。以温水下十丸。
治时气得汗后。心神狂乱方。
铁粉（半两） 野猪粪（半两烧灰） 生地黄（二两烧灰）
上件药都细研为末。以粟米饭和丸。如梧桐子大。不计时候。以人参汤下三十丸。
治时气已得汗。热毒不解。心烦躁闷。言语不定。小便赤涩。大便不通。狂乱欲走
。宜
川大黄（二两锉碎微炒） 黄芩（一两半） 栀子仁（一两半） 大青（二两） 龙胆
（一两去
芦头） 苦参（一两锉） 川朴硝（二两细研）
上件药。捣罗为末。入朴硝研匀。炼蜜和捣三五百杵。丸如梧桐子大。不计时候。以麦
门冬汤。下三十丸。
治时气热毒。心神烦躁。狂乱欲走。宜服珠粉丸方。
珠粉（一两研） 犀角屑（一两） 朱砂（半两细研） 甘草（二两锉生用） 苦参（一
两锉）
川朴硝（一两细研）
上件药。捣罗为末。入研了药令匀。炼蜜和丸。如梧桐子大。不计时候。以人参汤。下
三十丸。
又方。\x
上以蓝靛半大匙。以新汲水一盏。调分匀。顿服之。
Formulas for Treating Epidemic Febrile Diseases Manifesting as Mania
Epidemic febrile diseases manifesting as mania are caused by the flourishing of heat-toxin qi. Patients may discard their clothes and run, climb to high places and sing, or go without food for several days, scaling walls and climbing onto roofs. These behaviors are not actions they would normally perform.
For epidemic febrile diseases where heat-toxin attacks the heart, causing redness of the face and eyes, mania, and loss of recognition, the Gardenia Powder Formula (Zhizi San) is suitable.
Ingredients: Zhizi Ren (Gardeniae Fructus), Weirui (Polygonati Rhizoma), Fushen (Poria with Hostwood), Maimendong (Ophiopogonis Radix, core removed), Chuan Shengma (Cimicifugae Rhizoma), Zhi Mu (Anemarrhenae Rhizoma), Xijiao Xie (Rhinocerotis Cornu, shaved), Shashen (Adenophorae Radix, radix head removed), Huangqin (Scutellariae Radix), Chuan Dahuang (Rhei Radix et Rhizoma, sliced and slightly stir-fried), Gancao (Glycyrrhizae Radix et Rhizoma, honey-fried until slightly red and sliced). Each ingredient weighs one qianliang (approx. 30g in Song dynasty context, here kept as 'one liang').
Preparation and Administration: Pound and sieve the above ingredients into a powder. Take four qian (approx. 12g) per dose. Add one zhong (approx. 200ml) of water, decoct until six fen remains, remove dregs. Take warm at any time.
For epidemic febrile diseases causing mental restlessness and mania with excessive speech, this formula is suitable.
Ingredients: Jizi (Chicken Egg, take two egg whites), Baimi (White Honey, half he), Shengdihuang Zhi (Fresh Rehmanniae Radix Juice, one he), Chuan Dahuang (Rhei Radix et Rhizoma, half liang, sliced, slightly stir-fried, and pounded into powder).
Preparation and Administration: Mix the above ingredients evenly and take in one dose. Continue until bowel movement occurs.
For epidemic febrile diseases with severe heat, mental mania, and urge to run, the Dictamni Powder Formula (Baixianpi San) is suitable.
Ingredients: Baixianpi (Dictamni Cortex, one and a half liang), Daqing (Baphicacanthi Cuspidis Folium et Caulis), Lingyangjiao Xie (Saigae Tataricae Cornu, shaved), Xuanshen (Scrophulariae Radix), Zhizi Ren (Gardeniae Fructus), Ziqin (Scutellariae Radix), Chuan Dahuang (Rhei Radix et Rhizoma, honey-fried until slightly red and sliced), Digupi (Lycii Cortex). Each of the above weighs three fen.
Preparation and Administration: Pound and sieve the above ingredients into a powder. Take five qian (approx. 15g) per dose. Add one da zhan (approx. 250ml) of water, decoct until five fen remains, remove dregs. Take warm at any time.
Another Formula.
Ingredients: Maimendong (Ophiopogonis Radix, three liang, core removed), Xingren (Armeniacae Semen, one or two liang, soaked in water, skin and tip removed, double-kernel removed, bran-fried until slightly yellow), Gancao (Glycyrrhizae Radix et Rhizoma, one liang, honey-fried until slightly red and sliced), Baixianpi (Dictamni Cortex, two liang), Shenggan Dihuang (Dry Rehmanniae Radix, two liang), Huangqin (Scutellariae Radix, one liang).
Preparation and Administration: Pound and sieve the above ingredients into a powder. Take five qian per dose. Add one da zhan of water and two stems of Congbai (Allii Fistulosi Bulbus), decoct until five fen remains, remove dregs. Take warm at any time.
For epidemic febrile diseases where heat-toxin attacks the heart, causing unstable speech, mental mania, irritability, and inability to sleep or lie down, the Rhinoceros Horn Powder Formula (Xijiao San) is suitable.
Ingredients: Xijiao Xie (Rhinocerotis Cornu, shaved), Longchi (Dentis Mamuthi Fosilia), Ziqin (Scutellariae Radix), Shashen (Adenophorae Radix, radix head removed), Weirui (Polygonati Rhizoma), Maimendong (Ophiopogonis Radix, core removed), Chuan Shengma (Cimicifugae Rhizoma), Chi Fuling (Poria cum Risu, red), Chishaoyao (Paeoniae Radix Rubra), Xingren (Armeniacae Semen), Gancao (Glycyrrhizae Radix et Rhizoma).
Preparation and Administration: Pound and sieve the above ingredients into a powder. Take five qian per dose. Add one da zhan of water, decoct until five fen remains, remove dregs. Take warm at any time.
For epidemic febrile diseases manifesting as mania, shouting, and loss of recognition, this formula is suitable.
Ingredients: Huanglian (Coptidis Rhizoma, one liang, mustache removed), Qinjiao (Gentianae Macrophyllae Radix, one liang, sprout removed), Zhizi Ren (Gardeniae Fructus, one liang), Tiefen (Ferrum Oxydatum Rubrum, two liang).
Preparation and Administration: Pound and sieve finely into a powder. Take two qian at any time, mixed with fresh drawn water.
Another Formula.
Ingredients: Zhizi Ren (Gardeniae Fructus, half liang), Chi (Sojae Semen Praeparatum, one he), Congbai (Allii Fistulosi Bulbus, five stems).
Preparation and Administration: Add two da zhan of water, decoct until one zhan remains, remove dregs. Divide into two warm doses.
Formula for Treating Epidemic Febrile Disease Manifesting as Mania.
Ingredients: Hanshuishi (Aragonitum, one liang), Mayaxiao (Natrii Sulfas, one liang).
Preparation and Administration: Grind finely into powder. Take one qian at any time, mixed with fresh drawn water.
Another Formula.
Ingredients: Qinjiao (Gentianae Macrophyllae Radix, half liang, sprout removed), Daqing (Baphicacanthi Cuspidis Folium et Caulis, half liang), Gancao (Glycyrrhizae Radix et Rhizoma, half liang, honey-fried until slightly red and sliced).
Preparation and Administration: Pound and sieve finely into a powder. Take two qian at any time, mixed with Shengdihuang Zhi (Fresh Rehmanniae Radix Juice).
Formula for Treating Epidemic Febrile Disease with Excessive Heat Leading to Epileptic Mania or Occasional Coma.
Ingredients: Hanshuishi (Aragonitum, half liang), Zhusha (Cinnabaris, one fen), Qianshuang (Plumbum Subcarbonas, one fen).
Preparation and Administration: Grind all ingredients into fine powder. Mix with soft cooked rice to form pills the size of Sophora seeds. Take ten pills at any time with warm water.
Formula for Treating Mental Mania After Sweating from Epidemic Febrile Disease.
Ingredients: Tiefen (Ferrum Oxydatum Rubrum, half liang), Yezhufen (Excreta Porci, half liang, burnt to ash), Shengdihuang (Rehmanniae Radix, two liang, burnt to ash).
Preparation and Administration: Grind all ingredients finely into powder. Mix with millet rice to form pills the size of Sophora seeds. Take thirty pills at any time with Renshen Tang (Ginseng Decoction).
For epidemic febrile disease where sweating has occurred but heat-toxin remains unresolved, causing mental irritability, unstable speech, dark and scanty urination, constipation, and manic urge to run, this formula is suitable.
Ingredients: Chuan Dahuang (Rhei Radix et Rhizoma, two liang, sliced and slightly stir-fried), Huangqin (Scutellariae Radix, one and a half liang), Zhizi Ren (Gardeniae Fructus, one and a half liang), Daqing (Baphicacanthi Cuspidis Folium et Caulis, two liang), Longdan (Gentianae Radix, one liang, radix head removed), Kushen (Sophorae Flavescentis Radix, one liang, sliced), Chuan Puxiao (Natrii Sulfas, two liang, finely ground).
Preparation and Administration: Pound and sieve into powder, mix with Puxiao evenly. Knead with refined honey for 300-500 strikes to form pills the size of Sophora seeds. Take thirty pills at any time with Maimendong Tang (Ophiopogon Decoction).
For epidemic febrile diseases with heat-toxin, mental irritability, and manic urge to run, the Pearl Powder Pill Formula (Zhu Fen Wan) is suitable.
Ingredients: Zhu Fen (Margarita Pulvis, one liang, ground), Xijiao Xie (Rhinocerotis Cornu, one liang), Zhusha (Cinnabaris, half liang, finely ground), Gancao (Glycyrrhizae Radix et Rhizoma, two liang, sliced and used raw), Kushen (Sophorae Flavescentis Radix, one liang, sliced), Chuan Puxiao (Natrii Sulfas, one liang, finely ground).
Preparation and Administration: Pound and sieve into powder, mix thoroughly with the already ground ingredients. Knead with refined honey to form pills the size of Sophora seeds. Take thirty pills at any time with Renshen Tang (Ginseng Decoction).
Another Formula.
Administration: Take half a large spoonful of Lanyi (Indigo Naturalis), mix with one zhan of fresh drawn water, stir evenly, and take in one dose.