夫疟者。皆因风寒之气所为也。故夏伤于暑。秋必病疟。邪气客于阳明。则寒栗鼓颔。
巨阳虚。即头项腰脊痛。三阳俱虚。即骨寒而痛。故中外皆寒。阴气逆极。即复出之外。故
阳盛
伤于
藏
至
远
夫肝病为疟者。令人色苍苍然。气息喘闷战掉。状如死者。若人本来少于悲恚。忽尔嗔
怒。
所伤
夫心病为疟者。令人心烦。其病欲饮清水。多热少寒。若人本来心性和雅。而忽卒急。
反于常伦。或言未终。便住。以手剔脚爪。其人必死。名曰行尸。此心病之证也。虚则补之。
实
出
肺
尔
里
手
己
弦小紧者可下之。弦迟者宜温药。若脉数而紧者。可发其汗。凡脉浮大者。不可针灸也。凡
疗疟。于发前先如食顷。乃可以治之。过则失时也。
治肝疟。上焦壅滞。心烦头疼。寒热不止。肌肤消瘦。不能下食。知母散方。
知母（一两） 虎头骨（一两半涂酥炙黄） 地骨皮（一两） 川升麻（一两） 鳖甲
（二两涂
醋炙令黄去裙 ）
两去
苗） 石膏（二两）
上件药。捣筛为散。每服四钱。以水一中盏。入香豉五十粒。煎至六分。去滓。不计时
候温服。
治肝热。或为肝疟。颜色苍苍。颤掉气喘。变成劳疟。积年不瘥。宜服蜀漆丸方。
蜀漆（半两） 乌梅肉（半两微炒） 石膏（一两细研） 鳖甲（一两涂醋炙令黄去裙
） 恒
山（
麝香
（半两
上件药。捣罗为末。入研了药。都研令匀。炼蜜和捣三二百杵。丸如梧桐子大。每服空
心。以温酒下二十丸。晚食前再服。粥饮下亦得。
治肝疟久不瘥。乌梅丸方。
乌梅肉（一两酒拌微炒） 恒山（一两锉） 知母（半两） 犀角屑（半两） 朱砂（半
两细研）
龙骨（半
两）
甘草（半两
上件药。捣罗为末。入研了药。都研令匀。炼蜜和捣三二百杵。丸如梧桐子大。每服空
心。以温酒下二十丸。晚食前再服。
治心疟。令人心烦渴。欲得饮水。寒热不歇。乍来乍去。不思饮食。恒山散方。
恒山（一两锉） 柴胡（一两去苗） 栀子仁（一两） 石膏（二两） 乌梅肉（三七
枚微炒）
甘草（一两炙微赤锉） 蜀漆（二两） 鳖甲（二两涂醋炙令黄去裙 ）
上件药。捣粗罗为散。每服五钱。以水一大盏。入竹叶二七片。豉五十粒。煎
至五分。去滓。不计时候温服。
治心疟。发歇不定。大黄丸方。
川大黄（半两锉碎微炒） 恒山〔一两（分）〕 香豉（四十九粒） 砒霜（一分细研）
鳖甲
（
上件药。捣罗为末。入后三味。研令匀。以醋煮面糊和丸。如梧桐子大。每服食前。用
桃仁冷醋汤下二丸。忌食热物。
治心疟。神验朱砂丸方。
光明砂（半两细研） 恒山（一两） 杏仁（十枚汤浸去皮尖双仁麸炒微黄）
上件药。捣罗为末。研入朱砂令匀。炼蜜和丸。如梧桐子大。未发前。以粥饮下十五丸
欲发时再服。
又方。
麝香（一分） 金箔（三十片） 黄丹（一分炒令紫色） 朱砂（一两） 砒霜（一分）
上件药。都细研令匀。用粳米饭和丸。如梧桐子大。男左女右。中指节上。用绯帛裹系
一丸。发前。以冷醋汤下一丸。忌食热物。
治脾疟。由热气内伤不泄。故为脾疟。令人病肠中热痛。外寒。肠中鸣。转汗出。
恒山
恒山（一两锉） 甘草（半两炙微赤锉） 知母（一两） 豉（一合） 鳖甲（一两涂
醋炙令黄
去裙 ） 麝香（一分细研）
上件药。捣罗为末。入麝香研匀。炼蜜和丸。如梧桐子大。未发前。以温酒服二十丸。
临发再服。
治脾疟。霍乱吐逆下利。人参丸方。
人参（一两去芦头） 鳖甲（一两涂醋炙令黄去裙 ） 高良姜（一两锉） 白茯苓（一
两）
桂心（一两） 甘草（一两炙微赤锉） 麝香（一分细研）
上件药。捣罗为末。入麝香研匀。炼蜜和捣三二百杵。丸如弹子大。以温酒一合半。纳
药一丸。研破。食前服之。
治肺疟。来去不定。其状。令人心寒。甚即发热。热则多惊。如有所见者。犀角散
方。
（半两
锉） 糯米（八十一粒） 甘草（半两炙微赤锉）
上件药。都捣令碎。以水五大盏。煎至二盏半。去滓。分为五服。于发时前。不计时候
温服。
治肺疟。烦热呕逆方。
知母（一两） 柴胡（二两去苗） 人参（一两去芦头） 甘草（半两炙微赤锉） 麦
门冬（一
两去心） 杏仁（一两汤浸去皮尖双仁麸炒微黄）
上件药。捣筛为散。每服四钱。以水一中盏。煎至六分。去滓。不计时候温服。
治肾疟。腰背痛。手足寒。食少无力。乌梅丸方。
乌梅肉（一两微炒） 桂心（一两） 甘草（一两炙微赤锉） 虎头骨（二两涂酥炙令
黄） 人
参（一
香
（一分细
（一
两） 肉苁蓉（一两酒
上件药。捣罗为末。入麝香研匀。炼蜜和捣三五百杵。丸如梧桐子大。每于食前。以粥
饮下二十丸。渐加至三十丸。
治肾热为疟。令人凄凄。腰脊痛宛转。大便难。忽然手足寒。恒山散方。\x
恒山（一两） 乌梅肉〔一两（二七枚）捣〕 香豉（一合） 葱白（一握） 桃仁（半
两汤浸
去
皮尖麸炒微黄）
上件药。细锉。都以水二大盏。煎至一盏半。去滓。分为三服。于欲发时前服尽。
Malaria is a disease caused by the invasion of wind-cold pathogenic factors. Therefore, if one is injured by summer-heat in summer, one will inevitably suffer from malaria in autumn. If the pathogenic factor lodges in the Yangming channel, chills and mandibular tremors occur.
If the Juyang (Taiyang) channel is deficient, pain in the head, neck, waist, and spine results. If all three Yang channels (Taiyang, Yangming, Shaoyang) are deficient, bone coldness and pain ensue, causing coldness throughout the interior and exterior of the body. When Yin qi reverses to an extreme, it returns to the exterior, leading to... [Text fragmentary].
In cases of malaria originating from Liver pathology, the complexion appears cyanotic, breathing is panting and obstructed, and the body trembles and quivers, resembling a corpse. If a person who was previously free from sorrow and anger suddenly becomes enraged... [Text fragmentary].
In cases of malaria originating from Heart pathology, the patient experiences mental restlessness, desires to drink clear water, and exhibits more heat than cold. If a person whose nature is typically gentle and elegant suddenly becomes irritable, deviating from their usual demeanor, or stops speaking abruptly, picking at their toenails, such a patient will surely die; this condition is named "Walking Corpse." This is the syndrome of Heart malaria. Deficiency syndromes are treated with tonification... [Text fragmentary].
A pulse that is wiry, small, and tight indicates that purgation may be used. A wiry and slow pulse suggests the suitability of warm herbs. If the pulse is rapid and tight, sweating therapy may be applied. For any pulse that is floating and large, acupuncture and moxibustion are contraindicated. In treating malaria, intervention should be performed approximately the time it takes to eat a meal before the onset of symptoms; otherwise, the timing is missed.
For Liver Malaria characterized by stagnation in the Upper Jiao, mental restlessness, headache, unremitting alternating chills and fever, emaciation, and inability to eat: Zhi Mu San Powder.
Zhi Mu (Motherwort Root, 1 liang), Hutou Gu (Tiger Skull Bone, 1.5 liang, processed with butter until yellow), Digupi (Cortex Lycii, 1 liang), Chuan Shengma (Rhizoma Cimicifugae, 1 liang), Biejia (Carapax et Plastrum Testudinis, 2 liang, processed with vinegar until yellow, remove skirt), [Missing Herb] (2 liang, remove sprouts), Shigao (Gypsum Fibrosum, 2 liang).
Crush and sieve the above ingredients into a powder. Take 4 qian per dose, add 50 grains of Xiangchi (Prepared Soybean), and decoct in one zhong of water until reduced to 6 fen. Strain and take warm at any time.
For Liver Heat or Liver Malaria presenting with cyanotic complexion, trembling, panting, evolving into chronic malaria (Lao Malaria) persisting for years: Shuqi Wan Pill.
Shuqi (Herba Euphorbiae Humifusae, 0.5 liang), Wumei Rou (Sarcocarpus Pruni Mume, 0.5 liang, slightly stir-fried), Shigao (Gypsum Fibrosum, 1 liang, finely ground), Biejia (Carapax et Plastrum Testudinis, 1 liang, processed with vinegar until yellow, remove skirt), [Missing Herb, likely Changshan, 1 liang], Shexiang (Moschus, 0.5 liang).
Pulverize the ingredients, mix thoroughly with the ground components. Combine with refined honey and pound 300-200 times to form pills the size of Sophora seeds. Take 20 pills on an empty stomach with warm wine, and another dose after evening meal. Decoction with congee water is also acceptable.
For chronic Liver Malaria not resolving: Wumei Wan Pill.
Wumei Rou (Sarcocarpus Pruni Mume, 1 liang, mixed with wine and slightly stir-fried), [Changshan/Shan Jin, 1 liang, crushed], Zhi Mu (Motherwort Root, 0.5 liang), Xi Jiao Xie (Horn Rhinocerotis, 0.5 liang), Zhusha (Cinnabar, 0.5 liang, finely ground), Longgu (Os Draconis, 0.5 liang), Gancao (Radix Glycyrrhizae, 0.5 liang).
Pulverize, mix thoroughly with ground components. Combine with refined honey and pound 300-200 times to form pills the size of Sophora seeds. Take 20 pills on an empty stomach with warm wine, and another dose after evening meal.
For Heart Malaria presenting with mental restlessness, thirst, desire for water, unremitting alternating chills and fever, irregular onset, and loss of appetite: Hengshan San Powder.
Hengshan (Radix Dichroae, 1 liang, crushed), Chaihu (Radix Bupleuri, 1 liang, remove sprouts), Zhizi Ren (Semen Gardeniae, 1 liang), Shigao (Gypsum Fibrosum, 2 liang), Wumei Rou (Sarcocarpus Pruni Mume, 27-21 pieces, slightly stir-fried), Gancao (Radix Glycyrrhizae, 1 liang, honey-fried until slightly red, crushed), Shuqi (Herba Euphorbiae Humifusae, 2 liang), Biejia (Carapax et Plastrum Testudinis, 2 liang, processed with vinegar until yellow, remove skirt).
Coarsely pulverize. Take 5 qian per dose, add 14 leaves of Zhuye (Bamboo Leaf) and 50 grains of Chi (Prepared Soybean), decoct in one da zhong of water until reduced to 5 fen. Strain and take warm at any time.
For Heart Malaria with irregular intervals of attack: Dahuang Wan Pill.
Chuan Dahuang (Radix et Rhizoma Rhei, 0.5 liang, crushed, slightly stir-fried), Hengshan (Radix Dichroae, 1 liang), Xiangchi (Prepared Soybean, 49 grains), Pishuang (Arsenic Trioxide, 0.1 fen, finely ground), Biejia (Carapax et Plastrum Testudinis, [missing]).
Pulverize, mix with the subsequent three ingredients. Bind with paste made from flour boiled in vinegar to form pills the size of Sophora seeds. Take 2 pills before meals with cold vinegar decoction of Taoren (Semen Persicae). Avoid hot foods.
For Heart Malaria, Divine Effect Zhusha Wan Pill:
Guangmingsha (Lapis Cinabris, 0.5 liang, finely ground), Hengshan (Radix Dichroae, 1 liang), Xingren (Semen Armeniacae Amarum, 10 pieces, soaked in water, skin and pointed end removed, double-kernel, bran-fried until slightly yellow).
Pulverize, mix thoroughly with Zhusha (Cinnabar). Combine with refined honey to form pills the size of Sophora seeds. Take 15 pills with congee water before onset. Repeat when symptoms are imminent.
Another Prescription:
Shexiang (Moschus, 0.1 fen), Jinbo (Folium Aurum, 30 pieces), Huangdan (Minium, 0.1 fen, fried until purple), Zhusha (Cinnabar, 1 liang), Pishuang (Arsenic Trioxide, 0.1 fen).
Finely grind and mix uniformly. Bind with Jingmi (Oryza Sativa Glutinosa Rice) paste to form pills the size of Sophora seeds. For males, tie one pill wrapped in crimson silk to the joint of the left middle finger; for females, the right middle finger. Before onset, take one pill with cold vinegar decoction. Avoid hot foods.
For Spleen Malaria caused by internal injury from heat qi failing to vent: Hengshan San Powder.
This condition causes heat pain in the intestines, external aversion to cold, borborygmus, and sweating.
Hengshan (Radix Dichroae, 1 liang, crushed), Gancao (Radix Glycyrrhizae, 0.5 liang, honey-fried until slightly red, crushed), Zhi Mu (Motherwort Root, 1 liang), Chi (Prepared Soybean, 1 he), Biejia (Carapax et Plastrum Testudinis, 1 liang, processed with vinegar until yellow, remove skirt), Shexiang (Moschus, 0.1 fen, finely ground).
Pulverize, mix thoroughly with Shexiang. Combine with refined honey to form pills the size of Sophora seeds. Take 20 pills with warm wine before onset. Repeat dose just before symptoms appear.
For Spleen Malaria presenting with Huoluan (Colic with vomiting and diarrhea): Renshen Wan Pill.
Renshen (Radix Ginseng, 1 liang, remove rhizome), Biejia (Carapax et Plastrum Testudinis, 1 liang, processed with vinegar until yellow, remove skirt), Gaoliangjiang (Rhizoma Alpiniae Officinarum, 1 liang, crushed), Baifuling (Poria, 1 liang), Guixin (Cortex Cinnamomi, 1 liang), Gancao (Radix Glycyrrhizae, 1 liang, honey-fried until slightly red, crushed), Shexiang (Moschus, 0.1 fen, finely ground).
Pulverize, mix thoroughly with Shexiang. Combine with refined honey and pound 300-200 times to form pills the size of a bullet. Dissolve one pill in 1.5 he of warm wine, crush, and take before meals.
For Lung Malaria with irregular onset, characterized by initial chill followed by high fever, frequent fright, and visual hallucinations: Xijiao San Powder.
[Xijiao/Rhinoceros Horn, 0.5 liang, crushed], Nuomi (Oryza Sativa Glutinosa, 81 grains), Gancao (Radix Glycyrrhizae, 0.5 liang, honey-fried until slightly red, crushed).
Crush all ingredients. Decoct in 5 da zhang of water until reduced to 2.5 zhang. Strain. Divide into five doses. Take warm at any time before onset.
For Lung Malaria with irritability, heat, and vomiting:
Zhi Mu (Motherwort Root, 1 liang), Chaihu (Radix Bupleuri, 2 liang, remove sprouts), Renshen (Radix Ginseng, 1 liang, remove rhizome), Gancao (Radix Glycyrrhizae, 0.5 liang, honey-fried until slightly red, crushed), Maidong (Radix Ophiopogonis, 1 liang, remove heart), Xingren (Semen Armeniacae Amarum, 1 liang, soaked in water, skin and pointed end removed, double-kernel, bran-fried until slightly yellow).
Pulverize and sieve. Take 4 qian per dose, decoct in one zhong of water until reduced to 6 fen. Strain and take warm at any time.
For Kidney Malaria presenting with lower back and leg pain, cold hands and feet, poor appetite, and weakness: Wumei Wan Pill.
Wumei Rou (Sarcocarpus Pruni Mume, 1 liang, slightly stir-fried), Guixin (Cortex Cinnamomi, 1 liang), Gancao (Radix Glycyrrhizae, 1 liang, honey-fried until slightly red, crushed), Hutou Gu (Tiger Skull Bone, 2 liang, processed with butter until yellow), Renshen (Radix Ginseng, 1 liang), [Missing Herb, likely Shexiang, 0.1 fen, finely ground], [Missing Herb, 1 liang], Roushou Rong (Cynomorium, 1 liang, wine-soaked).
Pulverize, mix thoroughly with Shexiang. Combine with refined honey and pound 300-500 times to form pills the size of Sophora seeds. Take 20 pills with congee water before meals, gradually increasing to 30 pills.
For Malaria caused by Kidney Heat, presenting with shivering, waist and spine pain with rolling discomfort, difficult defecation, and sudden coldness of hands and feet: Hengshan San Powder.
Hengshan (Radix Dichroae, 1 liang), Wumei Rou (Sarcocarpus Pruni Mume, 1 liang or 14 pieces, crushed), Xiangchi (Prepared Soybean, 1 he), Congbai (Scallion White, one handful), Taoren (Semen Persicae, 0.5 liang, soaked in water, skin and pointed end removed, bran-fried until slightly yellow).
Finely crush. Decoct in 2 da zhang of water until reduced to 1.5 zhang. Strain. Divide into three doses. Take completely just before onset.